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M. thermoresistible (build 8) TH_0435 (pnp)

annotation: PROBABLE 5'-METHYLTHIOADENOSINE PHOSPHORYLASE PNP (MTA PHOSPHORYLASE)
coordinates: 952737 - 953513
length: 259

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_0435 pnp - 100% (259) PROBABLE 5'-METHYLTHIOADENOSINE PHOSPHORYLASE PNP (MTA PHOSPHORYLASE)
M. thermoresistible (build 8) TH_2259 deoD 7e-10 28.88% (232) PROBABLE PURINE NUCLEOSIDE PHOSPHORYLASE DEOD (INOSINE

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0549 pnp 1e-114 74.42% (258) 5'-methylthioadenosine phosphorylase
M. gilvum PYR-GCK Mflv_4828 - 1e-10 28.14% (231) purine nucleoside phosphorylase
M. tuberculosis H37Rv Rv0535 pnp 1e-114 74.42% (258) 5'-methylthioadenosine phosphorylase
M. leprae Br4923 MLBr_00707 deoD 4e-09 27.31% (227) purine nucleoside phosphorylase
M. abscessus ATCC 19977 MAB_3956c - 1e-118 79.07% (258) 5'-methylthioadenosine phosphorylase
M. marinum M MMAR_0881 pnp 1e-117 76.36% (258) 5'-methylthioadenosine phosphorylase, Pnp
M. avium 104 MAV_4610 mtaP 1e-116 75.58% (258) 5'-methylthioadenosine phosphorylase
M. smegmatis MC2 155 MSMEG_0990 mtaP 1e-128 83.33% (258) 5'-methylthioadenosine phosphorylase
M. ulcerans Agy99 MUL_0634 pnp 1e-116 75.97% (258) 5'-methylthioadenosine phosphorylase
M. vanbaalenii PYR-1 Mvan_0881 - 1e-126 81.01% (258) 5'-methylthioadenosine phosphorylase

CLUSTAL 2.0.9 multiple sequence alignment


Mb0549|M.bovis_AF2122/97            ----------------------MHNNGRMLGVIGGSGFY----TFFGSDT
Rv0535|M.tuberculosis_H37Rv         ----------------------MHNNGRMLGVIGGSGFY----TFFGSDT
MMAR_0881|M.marinum_M               ----------------------MHNNEPMLAVIGGSGFY----SFFESDV
MUL_0634|M.ulcerans_Agy99           ----------------------MHNNEPMLAVIGGSGFY----SFFESDV
MAV_4610|M.avium_104                ----------------------MHHNGRMLGVIGGSGFY----IFFGSDA
MSMEG_0990|M.smegmatis_MC2_155      ---------------------------MMLGVIGGSGFY----TFFGSDA
Mvan_0881|M.vanbaalenii_PYR-1       ----------------------------MLGVIGGSGFY----SFFGSDA
TH_0435|M.thermoresistible__bu      ----------------------------MLAVIGGSGFY----SFFGPDA
MAB_3956c|M.abscessus_ATCC_199      ----------------------------MLAVIGGSGFY----SFFDKPV
Mflv_4828|M.gilvum_PYR-GCK          ----MDDPGVLAQQAADELRRRTGVDTHDVAVVLGSGWAPAATSLGEPDA
MLBr_00707|M.leprae_Br4923          MTYTLLDPDELARRAAQVIGERTGILKHDVAVVLGSGWSSAVAALGSSRA
                                                                 :.*: ***:      :    .

Mb0549|M.bovis_AF2122/97            RTVNSDTP-YGQPSAPITIG---TIGVHDVAFLPRHGAHHQYSAHAVPYR
Rv0535|M.tuberculosis_H37Rv         RTVNSDTP-YGQPSAPITIG---TIGVHDVAFLPRHGAHHQYSAHAVPYR
MMAR_0881|M.marinum_M               RTVNPDTP-YGRPSAPITIG---AVGEHEVAFLPRHGASHQYSAHTVPYR
MUL_0634|M.ulcerans_Agy99           RTVNPDTP-YGRPSAPITIG---AVGEHEVAFLPRHGASHQYSAHTVPYR
MAV_4610|M.avium_104                DDVTVDTP-YGPPSAPVTVG---AVGGHRVAFLPRHGARHEFSAHTVPYR
MSMEG_0990|M.smegmatis_MC2_155      RAVSVETP-YGPPSAPITVG---TVGDHEVAFLPRHGVKHEFSPHTVPYR
Mvan_0881|M.vanbaalenii_PYR-1       RSVTVDTP-YGPPSAAITVG---SVGAHEVAFLPRHGVRHEYSPHTVPYR
TH_0435|M.thermoresistible__bu      RTVTPDTP-YGAPSGPITIG---RVGQHEVAFLPRHGVDHEYSPHTVPYR
MAB_3956c|M.abscessus_ATCC_199      RTVTPATP-YGEPSAPITIG---LVGGREVAFLPRHGSRHEFSPHTVPYR
Mflv_4828|M.gilvum_PYR-GCK          AIPMADLPGFTPPSAQGHGGQVLSVRAGPHRVLVLLGRIHAYEGHNLRHV
MLBr_00707|M.leprae_Br4923          VFPQAELPGFITPNAAGHTGELLSVRIGAHRVLVLAGRIHPYEGHDLRHV
                                           * :  *..    *    :      .*   *  * :. * : : 

Mb0549|M.bovis_AF2122/97            AN-MWALRALGVRRVFGPCAVGSLDPELEPGAVVVPDQLVDRTSGRADTY
Rv0535|M.tuberculosis_H37Rv         AN-MWALRALGVRRVFGPCAVGSLDPELEPGAVVVPDQLVDRTSGRADTY
MMAR_0881|M.marinum_M               AN-MWALRALGARRVFAPCAVGSLNPRLGPGTVVVPDQLVDRTRGRADTY
MUL_0634|M.ulcerans_Agy99           AN-MWALRALGARRVFAPCAVGSLNPRLRPGTVVVPDQLVDRTRGRADTY
MAV_4610|M.avium_104                AN-LWALRKLGVRRVLAPCAVGSLVPELGPGAVVVPDQLVDRTRGRADTY
MSMEG_0990|M.smegmatis_MC2_155      AN-LWALRSLGVRRVFAPCAVGSLTPDLGPGSIVVPDQLVDRTSGRDDTY
Mvan_0881|M.vanbaalenii_PYR-1       AN-MWALRALGVRRVFGPCAVGSLDPQLGPGAMVVPDQLVDRTSGRPDTY
TH_0435|M.thermoresistible__bu      AN-MWALRALGVRRVFAPCAVGSLTPDLGPGSVVVPDQLVDRTAGRADTY
MAB_3956c|M.abscessus_ATCC_199      AN-MWALRAVGVRRVFAPCAVGSLTADLGPGAIVVPDQLVDRTSGRAQTY
Mflv_4828|M.gilvum_PYR-GCK          VHPVRTACAAGARTVVLTNAAGGVREDMTVGQPVLISDHLNLTARSP---
MLBr_00707|M.leprae_Br4923          VHPVRTACAAGARIIVLTNAAGGLRADMAVGQLVLISDHLNLTTRSP---
                                    .: : :    *.* :. . *.*.:   :  *  *: .: :: *       

Mb0549|M.bovis_AF2122/97            FDFGGVHAAFADPYCPTLRAAVTGLPGVVDGGTMVVIQGPRFSTRAESQW
Rv0535|M.tuberculosis_H37Rv         FDFGGVHAAFADPYCPTLRAAVTGLPGVVDGGTMVVIQGPRFSTRAESQW
MMAR_0881|M.marinum_M               FDSGGVHAAFADPYCPTLRSAVTDLPDVVDGATMVVIQGPRFSTRAESRW
MUL_0634|M.ulcerans_Agy99           FDSGGVHAAFADPYCPTLRSAVTDLPDVVDGATMVVIQGPRFSTRAESRW
MAV_4610|M.avium_104                FDSGAVHVDFADPYCPALREAVTGLPGVVDGGTMVVIQGPRFSTRAESRW
MSMEG_0990|M.smegmatis_MC2_155      FDSGGIHVAFADPYCPTLRAAATGLPGVVDGGTMVVIQGPRFSTRAESRW
Mvan_0881|M.vanbaalenii_PYR-1       FDSGGIHVGFADPYCPSLRAAVTGLPGVVDGGAMVVIQGPRFSTRAESRW
TH_0435|M.thermoresistible__bu      FDSGGIHVSFADPYCPELRAIAARQPGVVDGGTMVVIQGPRFSTRAESRW
MAB_3956c|M.abscessus_ATCC_199      FDSAGIHVEFADPYCPGLR-AVSLQPGTIDGGTMVVVQGPRFSTRAESRW
Mflv_4828|M.gilvum_PYR-GCK          -LVGAQFVDMVDAYSPALRALARDIDPSLTEGVYAGLPGPHYETPAEIRM
MLBr_00707|M.leprae_Br4923          -LVGTHFVDLTNAYTTRLRKLASDTDPTLTEGVYAAQPGPHYETPAEIRM
                                       .  .. :.:.* . **  .      :  .. .   **::.* ** : 

Mb0549|M.bovis_AF2122/97            FAAAGCNLVNMTGYPEAVLARELELCYAAIALVTDVDAGVAAGDGVKAAD
Rv0535|M.tuberculosis_H37Rv         FAAAGCNLVNMTGYPEAVLARELELCYAAIALVTDVDAGVAAGDGVKAAD
MMAR_0881|M.marinum_M               FAGAGFSLVNMTGYPEAVLARELELCYAAVALVTDVDAGVAVGEGVKAAD
MUL_0634|M.ulcerans_Agy99           FAGAGFSLVNMTGYPEAVLARELELCYAAVALVTDVDAGVAVGEGVKAAD
MAV_4610|M.avium_104                FASAGFSLVNMTGYPEAVLARELEMCYAAIALVTDLDAGVSAGEGVKAVE
MSMEG_0990|M.smegmatis_MC2_155      FASQGFTLVNMTGYPEAVLARELEMCYAAVALVTDLDAGIEVGSGVRAVD
Mvan_0881|M.vanbaalenii_PYR-1       FADQGFRLVNMTGYPESVLARELEMCYAAIALVTDVDAGVEHGQGVRAVD
TH_0435|M.thermoresistible__bu      YADQGFTLINMTGHPEAVLARELEMCYAAIALVTDLDAGVESGSGVRAVD
MAB_3956c|M.abscessus_ATCC_199      YASQGFTLVNMTGYPEAVLARELEICYAAIALVTDLDAGVEHGQGVRAVD
Mflv_4828|M.gilvum_PYR-GCK          LRTLGADLVGMSTVHETIAARACGAAVLGVSLVTNLAAGMT-GQPLSHEE
MLBr_00707|M.leprae_Br4923          LRMLGADLVGMSTVHETIAARAAGAEVLGVSLVTNLAAGIT-GKPLNHAE
                                        *  *:.*:   *:: **       .::***:: **:  *. :   :

Mb0549|M.bovis_AF2122/97            VFAAFGENIELLKRLVRAAIDRVADERTCTHCQHHAGVPLPFELP
Rv0535|M.tuberculosis_H37Rv         VFAAFGENIELLKRLVRAAIDRVADERTCTHCQHHAGVPLPFELP
MMAR_0881|M.marinum_M               VFAEFGENIEMLKKLVRAGIGRVAAERACTHCLMHAGVTLPFELP
MUL_0634|M.ulcerans_Agy99           VFAEFGENIEMLKKLVRAGIGRVAAERACTHCLMHAGVTLPFELP
MAV_4610|M.avium_104                VFAEFEKNIEPFKKLVRDAIGRVAAERSCTQCSPHAGVSLPIELP
MSMEG_0990|M.smegmatis_MC2_155      VFAEFERNMPPFKKLVFEALEAVEVERTCTHCLTHSGVQLPFELP
Mvan_0881|M.vanbaalenii_PYR-1       VFAEFERNLVPFKQLVHEAIEQVDAERTCTHCMPHEGVQLPFDLP
TH_0435|M.thermoresistible__bu      VFAEFRRNMEPFKKLVHEALDQVPGERTCRHCLAHDGVKLPFELP
MAB_3956c|M.abscessus_ATCC_199      VFAEFERNIGGFKELVRSAVTATESVDTCGHCRAHDGVTLPIELP
Mflv_4828|M.gilvum_PYR-GCK          VLAAGRQSATRMGSLLSAVIAGL----------------------
MLBr_00707|M.leprae_Br4923          VLAAGTASANRIGSLLADIIARF----------------------
                                    *:*    .   :  *:   :

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_0435	pnp	-	100% (259)	PROBABLE 5'-METHYLTHIOADENOSINE PHOSPHORYLASE PNP (MTA PHOSPHORYLASE)
M. thermoresistible (build 8)	TH_2259	deoD	7e-10	28.88% (232)	PROBABLE PURINE NUCLEOSIDE PHOSPHORYLASE DEOD (INOSINE