For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_2245 (cysQ)

annotation: POSSIBLE MONOPHOSPHATASE CYSQ
coordinates: 4394865 - 4395599
length: 245

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2245cysQ-100% (245)POSSIBLE MONOPHOSPHATASE CYSQ
M. thermoresistible (build 8)TH_2360-5e-2753.92% (102) 3'(2'),5'-bisphosphate nucleotidase, putative
M. thermoresistible (build 8)TH_2553-4e-1372.73% (44) PUTATIVE -

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2155ccysQ2e-6854.18% (251) hypothetical protein Mb2155c
M. gilvum PYR-GCKMflv_2273-6e-9974.79% (242) inositol monophosphatase
M. tuberculosis H37RvRv2131ccysQ2e-6854.18% (251) monophosphatase CysQ
M. leprae Br4923MLBr_01301-6e-6250.39% (254) putative inositol monophosphatase family protein
M. abscessus ATCC 19977MAB_2115-1e-6855.42% (249) inositol monophosphatase CysQ
M. marinum MMMAR_3456cysQ_11e-10276.67% (240) monophosphatase CysQ_1
M. avium 104MAV_2129-1e-10579.08% (239) 3'(2'),5'-bisphosphate nucleotidase, putative
M. smegmatis MC2 155MSMEG_4977-1e-10678.24% (239) 3'(2'),5'-bisphosphate nucleotidase, putative
M. ulcerans Agy99MUL_2730cysQ_11e-10176.25% (240) monophosphatase CysQ_1
M. vanbaalenii PYR-1Mvan_4421-5e-9874.38% (242) inositol monophosphatase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2273|M.gilvum_PYR-GCK          -----------MTDDHELAGRLATAAGALLLDVRAELAEATPEERKAAGD
Mvan_4421|M.vanbaalenii_PYR-1       -----------MTDDHALAAQLATEAGELLLDVRSELAGAPAEERKAAGD
MMAR_3456|M.marinum_M               ------------MNDHAVAAWLATEAGRLLLGVREEFAEAEVAQRKAAGD
MUL_2730|M.ulcerans_Agy99           ------------MNDHAVAAWLATEAGRLLLGVREEFAAAEGAQRKAAGD
MAV_2129|M.avium_104                ------------MNDHELAARLATEAGRLLLGVRDEFADAPASERKAAGD
MSMEG_4977|M.smegmatis_MC2_155      ------------MNDHELAARLATRAGDLLLDVRADFADAPAQDRKAAGD
TH_2245|M.thermoresistible__bu      ------------VNDHELAAGLAARAGDLLLTVRTELADAAASERKDAGD
Mb2155c|M.bovis_AF2122/97           MVSPAAPDLTDDLTDAELAADLAADAGKLLLQVRAEIGFDQPWTLGEAGD
Rv2131c|M.tuberculosis_H37Rv        MVSPAAPDLTDDLTDAELAADLAADAGKLLLQVRAEIGFDQPWTLGEAGD
MLBr_01301|M.leprae_Br4923          MASHDKRDYQAELTDAALAADLATAAGELLLEIREEIGFDQPRALGDAGD
MAB_2115|M.abscessus_ATCC_1997      ----------MTVSDAALAAELAHEAGQLLLQVRTELGFDDPKGLGAAGD
                                                  *  :*. **  ** *** :* ::.         ***

Mflv_2273|M.gilvum_PYR-GCK          KRAHDFLLAALTAERPEDAVLSEEGVDDPVRLSAQRVWIVDPLDGTREFS
Mvan_4421|M.vanbaalenii_PYR-1       KRSHDFLLAVLTAERPDDAVLSEEGVDDPVRLSARRVWIVDPLDGTREFS
MMAR_3456|M.marinum_M               KRSHDFLMDKLAAERPGDAVLSEEGADDPVRLCSERVWIVDPLDGTREFS
MUL_2730|M.ulcerans_Agy99           KRSHDFLMDKLAAERPGDAVLSEEGADDPVRLRSERVWIVDPLDGTREFS
MAV_2129|M.avium_104                KRSHDFLIEALAAERPGDAVLSEEGADDPVRLRSERVWIVDPLDGTREFS
MSMEG_4977|M.smegmatis_MC2_155      KQSHDFLMAELARQRPGDAVLSEEGVDDPARLDAERVWIVDPLDGTREFS
TH_2245|M.thermoresistible__bu      KRSHDFLMAELARLRSGDAVLSEEGADDPARLTSDRVWIVDPLDGTREFS
Mb2155c|M.bovis_AF2122/97           RQANSLLLRRLQAERPGDAVLSEEAHDDLARLKSDRVWIIDPLDGTREFS
Rv2131c|M.tuberculosis_H37Rv        RQANSLLLRRLQAERPGDAVLSEEAHDDLARLKSDRVWIIDPLDGTREFS
MLBr_01301|M.leprae_Br4923          RLANSLLLSRLRAERPGDAVLSEEAHDDRVRLQAGRVWIIDPLDGTREFS
MAB_2115|M.abscessus_ATCC_1997      KRSNTLLLERLAAERPADAVLSEEAVDDKARLGAQRVWIIDPLDGTREFG
                                    : :: :*:  *   *. *******. ** .** : ****:*********.

Mflv_2273|M.gilvum_PYR-GCK          ELGRTDWAVHVALWERTG-----SGGELVAGAVALPAQGVTLVTPTVVAP
Mvan_4421|M.vanbaalenii_PYR-1       ELGRTDWAVHVALWERNG-----SSGELVAGAVALPAQGATLATPTVPAP
MMAR_3456|M.marinum_M               ELGRVDWAVHVALWQ---------AGQLVAGAVALPAQGITLATPHVEPP
MUL_2730|M.ulcerans_Agy99           ELGRVDWAVHVALWQ---------AGQLVAGAVALPAQDITLATPHVEPP
MAV_2129|M.avium_104                ELGRDDWAVHVALWE---------AGELVAGAVALPAQGVTFATPEVASP
MSMEG_4977|M.smegmatis_MC2_155      ELGREDWAVHVALWQ---------AGELVAGAVALPAQNMTLSTPEVAGP
TH_2245|M.thermoresistible__bu      EPGRDDWAVHVALWA---------GGTLAAGAVALPAQGVTLATPDVSAP
Mb2155c|M.bovis_AF2122/97           TPGRDDWAVHIALWRRSS----NGQPEITDAAVALPARGNVVYRTDTVTS
Rv2131c|M.tuberculosis_H37Rv        TPGRDDWAVHIALWRRSS----NGQPEITDAAVALPARGNVVYRTDTVTS
MLBr_01301|M.leprae_Br4923          TAGRTDWAVHIALWQRTTGGVADGRREITDAAVALPARGNRVYRSDTVTA
MAB_2115|M.abscessus_ATCC_1997      MEGRNDWAVHVALWQADG----DGGS-ITDAAVALPG-LDTVFRTDETRV
                                      ** *****:***             :. .*****.    .  .     

Mflv_2273|M.gilvum_PYR-GCK          PAG----PSSPRVVVSRTRPPAVALDVKDALNGTLVEMGSAGAKVASVVQ
Mvan_4421|M.vanbaalenii_PYR-1       PAG----PGAPRVVVSRTRPPAVALAVKEALGGTLIEMGSAGAKVASVVQ
MMAR_3456|M.marinum_M               PAA----PDRPRIVVSRTRPPAIALAVRDALDGTLVEMGSAGAKVASVVQ
MUL_2730|M.ulcerans_Agy99           PAA----PDRPRIVVSRTRPPAIALAVRDALDGTLVEMGSAGAKVASVVQ
MAV_2129|M.avium_104                PVA----PGKPRIVVSRTRPPAIALNVRDALDGVLVEMGSAGAKVASVVQ
MSMEG_4977|M.smegmatis_MC2_155      LPL----EGPPRVVVSRTRPPAIALAVRDALDGTLVEMGSAGAKVAAVIR
TH_2245|M.thermoresistible__bu      PPA----AAQPRIVVSRTRPPALALTVRDALNGTLVEMGSAGAKVAAVVQ
Mb2155c|M.bovis_AF2122/97           GAAPAGVPGTLRIAVSATRPPAVLHRIRQTLAIQPVSIGSAGAKAMAVID
Rv2131c|M.tuberculosis_H37Rv        GAAPAGVPGTLRIAVSATRPPAVLHRIRQTLAIQPVSIGSAGAKAMAVID
MLBr_01301|M.leprae_Br4923          GAVTGGVPNILRIAVSATRPPTILHRIRQKLAIEPVAIGSAGAKAMAVVD
MAB_2115|M.abscessus_ATCC_1997      TAAARAEADPIRIVASASRAPKFLTDMAERLNIELIPMGSAGAKAMAVVR
                                               *:..* :*.* .   : : *    : :******. :*: 

Mflv_2273|M.gilvum_PYR-GCK          GLSDVYVHAGGQYEWDSAAPVAVARAAGLHTSRIDGSPLVYNQRDSKLPD
Mvan_4421|M.vanbaalenii_PYR-1       GLADVYVHAGGQYEWDSAAPVAVARAAGLHTSRIDGSPLVYNRRDPLLPD
MMAR_3456|M.marinum_M               GLADVYVHAGGQFEWDSAAPVAVARSAGLHTSRIDGSALTYNRPDPKLPD
MUL_2730|M.ulcerans_Agy99           GLADVYVHAGGQFEWDSAAPVAVARSAGLHTSRIDGSALTYNRPDPKLPD
MAV_2129|M.avium_104                GLSDVYVHAGGQFEWDSAAPVAVARAAGLHTSRIDGSALAYNQPDPKLPD
MSMEG_4977|M.smegmatis_MC2_155      GHADVYVHAGGQYEWDSAAPVAVARAAGMHTSRIDGSPLRYNARDPRLPD
TH_2245|M.thermoresistible__bu      GRADVYVHAGGQYEWDNAAPAAVAVAAGLHTSRIDGSPLRYNNPDPRLPD
Mb2155c|M.bovis_AF2122/97           GYVDAYLHAGGQWEWDSAAPAGVMLAAGMHASRLDGSPLRYNQLDPYLPD
Rv2131c|M.tuberculosis_H37Rv        GYVDAYLHAGGQWEWDSAAPAGVMLAAGMHASRLDGSPLRYNQLDPYLPD
MLBr_01301|M.leprae_Br4923          GDVDAYLHVGGQWEWDSAAPAGVVLAAGMHASRLDGSPLRYNQLDPYLPD
MAB_2115|M.abscessus_ATCC_1997      GEADAYLHGGGQWEWDSAAPAGVVLAAGLHASRLDGSPLRYNEPHPYLPD
                                    *  *.*:* ***:***.***..*  :**:*:**:***.* **  .. ***

Mflv_2273|M.gilvum_PYR-GCK          LIVCRPELADAVLAVTTR---
Mvan_4421|M.vanbaalenii_PYR-1       LIVCRPELAEAVLAVTAG---
MMAR_3456|M.marinum_M               LVVCRPELATAVLAATG----
MUL_2730|M.ulcerans_Agy99           LVVCRPELATAVLAATG----
MAV_2129|M.avium_104                LVVCRPELADAVLAVTR----
MSMEG_4977|M.smegmatis_MC2_155      LIVCRPELAEQVLAVTRS---
TH_2245|M.thermoresistible__bu      ILVCRPELADAVLSAISAC--
Mb2155c|M.bovis_AF2122/97           LLMCRAEVAPILLGAIADAWR
Rv2131c|M.tuberculosis_H37Rv        LLMCRAEVAPILLGAIADAWR
MLBr_01301|M.leprae_Br4923          FVMCRADIAPILLGVIREVWQ
MAB_2115|M.abscessus_ATCC_1997      LIMCRPDLAPVLLDAVAGRA-
                                    :::**.::*  :* .