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VSPAAPDLTDDLTDAELAADLAADAGKLLLQVRAEIGFDQPWTLGEAGDRQANSLLLRRLQAERPGDAVL SEEAHDDLARLKSDRVWIIDPLDGTREFSTPGRDDWAVHIALWRRSSNGQPEITDAAVALPARGNVVYRT DTVTSGAAPAGVPGTLRIAVSATRPPAVLHRIRQTLAIQPVSIGSAGAKAMAVIDGYVDAYLHAGGQWEW DSAAPAGVMLAAGMHASRLDGSPLRYNQLDPYLPDLLMCRAEVAPILLGAIADAWR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2131c | cysQ | - | 100% (267) | POSSIBLE MONOPHOSPHATASE CYSQ |
| M. tuberculosis H37Rv | Rv2701c | suhB | 1e-06 | 30.73% (192) | extragenic suppressor protein SuhB |
| M. tuberculosis H37Rv | Rv3137 | - | 1e-05 | 38.10% (84) | monophosphatase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2155c | cysQ | 1e-153 | 100.00% (267) | hypothetical protein Mb2155c |
| M. gilvum PYR-GCK | Mflv_3047 | - | 6e-89 | 66.27% (255) | inositol monophosphatase |
| M. leprae Br4923 | MLBr_01301 | - | 1e-116 | 77.27% (264) | putative inositol monophosphatase family protein |
| M. abscessus ATCC 19977 | MAB_2115 | - | 1e-85 | 63.35% (251) | inositol monophosphatase CysQ |
| M. marinum M | MMAR_3112 | cysQ | 1e-122 | 80.39% (255) | monophosphatase CysQ |
| M. avium 104 | MAV_2360 | - | 1e-122 | 78.20% (266) | inositol monophosphatase family protein |
| M. smegmatis MC2 155 | MSMEG_4190 | - | 2e-91 | 65.48% (252) | inositol monophosphatase family protein |
| M. thermoresistible (build 8) | TH_2245 | cysQ | 3e-68 | 54.18% (251) | POSSIBLE MONOPHOSPHATASE CYSQ |
| M. ulcerans Agy99 | MUL_2362 | cysQ | 1e-121 | 80.00% (255) | monophosphatase CysQ |
| M. vanbaalenii PYR-1 | Mvan_3479 | - | 2e-90 | 66.67% (258) | inositol monophosphatase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3047|M.gilvum_PYR-GCK MARVLTWSTDRVSITDAALAAAVAEEAGELLLAMREQIG--FYDPYDLGD
Mvan_3479|M.vanbaalenii_PYR-1 -----------MILTDAALAAAVAEEAGELLLAMRERIGADFYDAYDLGD
MSMEG_4190|M.smegmatis_MC2_155 -----------MTSTDAELAAAVAKEAGELLLGIREEVG--FYDPYYLGD
Rv2131c|M.tuberculosis_H37Rv -MVSPAAPDLTDDLTDAELAADLAADAGKLLLQVRAEIG--FDQPWTLGE
Mb2155c|M.bovis_AF2122/97 -MVSPAAPDLTDDLTDAELAADLAADAGKLLLQVRAEIG--FDQPWTLGE
MLBr_01301|M.leprae_Br4923 -MASHDKRDYQAELTDAALAADLATAAGELLLEIREEIG--FDQPRALGD
MMAR_3112|M.marinum_M -MS----HSPARHLTDAELAADLAVDAGKLLLAVREEVG--FDHPWALGD
MUL_2362|M.ulcerans_Agy99 -MS----HPPARHLTDAELAADLAVDAGKLLLAVREEVG--FDLPWALGD
MAV_2360|M.avium_104 -MTP---RNPSDEMTDAALAADLAAEAGELLLKVRDEVG--FGYPWALGD
MAB_2115|M.abscessus_ATCC_1997 -----------MTVSDAALAAELAHEAGQLLLQVRTELG--FDDPKGLGA
TH_2245|M.thermoresistible__bu -------------VNDHELAAGLAARAGDLLLTVRTELAD--AAASERKD
.* *** :* **.*** :* .:. .
Mflv_3047|M.gilvum_PYR-GCK AGDSRANTLILDRLRAARPGDAILSEEAVDDPSRVDADRVWIVDPVDGTY
Mvan_3479|M.vanbaalenii_PYR-1 AGDKRANTLILDRLHRERPHDAVLSEEAVDDLSRVDADRVWIVDPVDGTH
MSMEG_4190|M.smegmatis_MC2_155 EGDRRSNALILKRLAEARPSDSVLSEEAADNLARVRADRVWIVDPVDGTR
Rv2131c|M.tuberculosis_H37Rv AGDRQANSLLLRRLQAERPGDAVLSEEAHDDLARLKSDRVWIIDPLDGTR
Mb2155c|M.bovis_AF2122/97 AGDRQANSLLLRRLQAERPGDAVLSEEAHDDLARLKSDRVWIIDPLDGTR
MLBr_01301|M.leprae_Br4923 AGDRLANSLLLSRLRAERPGDAVLSEEAHDDRVRLQAGRVWIIDPLDGTR
MMAR_3112|M.marinum_M AGDFQANSLLLRRLRAERPGDAVLSEEAHDDLVRLKSDRVWIIDPLDGTR
MUL_2362|M.ulcerans_Agy99 AGDFQANSLLLRRLRAERPGDAVLSEEAHDDLVRLKSDRVWIIDPLDGTR
MAV_2360|M.avium_104 AGDSLANALILGRLQAERPDDAVLSEEAYDDLSRLQHDRVWIIDPLDGTR
MAB_2115|M.abscessus_ATCC_1997 AGDKRSNTLLLERLAAERPADAVLSEEAVDDKARLGAQRVWIIDPLDGTR
TH_2245|M.thermoresistible__bu AGDKRSHDFLMAELARLRSGDAVLSEEGADDPARLTSDRVWIVDPLDGTR
** :: ::: .* *. *::****. *: *: ****:**:***
Mflv_3047|M.gilvum_PYR-GCK EYSMPGRADWAVHIALWRRD-------AGTLTDAAVALPARG-EVYRTDT
Mvan_3479|M.vanbaalenii_PYR-1 EYSMPGRADWAVHIALWQRAPRT---GAPTITDAAVALPARG-EVYRTDT
MSMEG_4190|M.smegmatis_MC2_155 EFSMPGREDWAVHIALWQRSVG----VDGGLSDAVVALPARG-EVYRSDT
Rv2131c|M.tuberculosis_H37Rv EFSTPGRDDWAVHIALWRRSS----NGQPEITDAAVALPARGNVVYRTDT
Mb2155c|M.bovis_AF2122/97 EFSTPGRDDWAVHIALWRRSS----NGQPEITDAAVALPARGNVVYRTDT
MLBr_01301|M.leprae_Br4923 EFSTAGRTDWAVHIALWQRTTGGVADGRREITDAAVALPARGNRVYRSDT
MMAR_3112|M.marinum_M EFSTRGRDDWAVHVALWQRRA----NGRPEITDAAVSLPARGNIVFRSDT
MUL_2362|M.ulcerans_Agy99 EFSTRGRDDWAVHVALWQRRA----NGRPEITDAAVSLPARGNIVFRSDT
MAV_2360|M.avium_104 EFSTPGRDDWAVHVALWQRPT----NGRREITDAAVSLPARGNIVYRSDT
MAB_2115|M.abscessus_ATCC_1997 EFGMEGRNDWAVHVALWQADG-----DGGSITDAAVALPGLD-TVFRTDE
TH_2245|M.thermoresistible__bu EFSEPGRDDWAVHVALWAGGT---------LAAGAVALPAQG-VTLATPD
*:. ** *****:*** :: ..*:**. . . :
Mflv_3047|M.gilvum_PYR-GCK VAP--PPPRVDGPIRITASSNRPPAVLWHIRDELDIELYRIGSAGAKAMA
Mvan_3479|M.vanbaalenii_PYR-1 VTP--PPPRAEGPIRVTASSNRPPAVLWRLREQLDIELVRIGSAGAKAMA
MSMEG_4190|M.smegmatis_MC2_155 ITP--PPPREPGPILITASSNRPPAVLWRMREHLDFRMVRIGSAGAKAMA
Rv2131c|M.tuberculosis_H37Rv VTSGAAPAGVPGTLRIAVSATRPPAVLHRIRQTLAIQPVSIGSAGAKAMA
Mb2155c|M.bovis_AF2122/97 VTSGAAPAGVPGTLRIAVSATRPPAVLHRIRQTLAIQPVSIGSAGAKAMA
MLBr_01301|M.leprae_Br4923 VTAGAVTGGVPNILRIAVSATRPPTILHRIRQKLAIEPVAIGSAGAKAMA
MMAR_3112|M.marinum_M VTADAAPVGVPDVIRVAVSTTRPPAILYHVSRTLAIQPVAIGSAGAKAMA
MUL_2362|M.ulcerans_Agy99 VTADAAPVGVPDVIRVAVSTTRPPAILYHVSRTLAIQPVAIGSAGAKAMA
MAV_2360|M.avium_104 VTASAARVGVTDTIRIAVSATRPPAVLHRMRQRLPIQPVAIGSAGAKAMA
MAB_2115|M.abscessus_ATCC_1997 TRVTAAARAEADPIRIVASASRAPKFLTDMAERLNIELIPMGSAGAKAMA
TH_2245|M.thermoresistible__bu VSAPPPAAAQP---RIVVSRTRPPALALTVRDALNGTLVEMGSAGAKVAA
:..* .*.* . : * :******. *
Mflv_3047|M.gilvum_PYR-GCK VVRGDVDAYLHAGGQWEWDSAAPAGVLWAAGLHASRLDGSPLIYNRPDPY
Mvan_3479|M.vanbaalenii_PYR-1 VVRGDVDAYLHAGGQWEWDSAAPAGVLWAAGMHASRIDGSPLIYNRRDPY
MSMEG_4190|M.smegmatis_MC2_155 VVRGDVDAYIHAGGQWEWDSAAPAGVLLAAGMHASRLDGSELRYNREDPY
Rv2131c|M.tuberculosis_H37Rv VIDGYVDAYLHAGGQWEWDSAAPAGVMLAAGMHASRLDGSPLRYNQLDPY
Mb2155c|M.bovis_AF2122/97 VIDGYVDAYLHAGGQWEWDSAAPAGVMLAAGMHASRLDGSPLRYNQLDPY
MLBr_01301|M.leprae_Br4923 VVDGDVDAYLHVGGQWEWDSAAPAGVVLAAGMHASRLDGSPLRYNQLDPY
MMAR_3112|M.marinum_M LIEGKADAYLHAGGQWEWDSAAPAGVVMAAGMHASRLDGSPLRYNQLDPY
MUL_2362|M.ulcerans_Agy99 LIEGKADAYLHAGGQWEWDSAAPAGVVMASGMHASRLDGSPLRYNQLDPY
MAV_2360|M.avium_104 IIDGVVDAYLHAGGQWEWDSAAPAGVVMAAGMHASRLDGSPMRYNQLDPY
MAB_2115|M.abscessus_ATCC_1997 VVRGEADAYLHGGGQWEWDSAAPAGVVLAAGLHASRLDGSPLRYNEPHPY
TH_2245|M.thermoresistible__bu VVQGRADVYVHAGGQYEWDNAAPAAVAVAAGLHTSRIDGSPLRYNNPDPR
:: * .*.*:* ***:***.****.* *:*:*:**:*** : **. .*
Mflv_3047|M.gilvum_PYR-GCK LPDLLMCRPEVAGRLLDVIWSAYR
Mvan_3479|M.vanbaalenii_PYR-1 LPDLLMCRPEVAGVLLEGIWSAYR
MSMEG_4190|M.smegmatis_MC2_155 LPDFVMCRRELAPVLLDAIGAAL-
Rv2131c|M.tuberculosis_H37Rv LPDLLMCRAEVAPILLGAIADAWR
Mb2155c|M.bovis_AF2122/97 LPDLLMCRAEVAPILLGAIADAWR
MLBr_01301|M.leprae_Br4923 LPDFVMCRADIAPILLGVIREVWQ
MMAR_3112|M.marinum_M LPDFVMCRPELAPVLLDAIRQVWR
MUL_2362|M.ulcerans_Agy99 LPDFVMCRPELAPVLLDAIRQVWR
MAV_2360|M.avium_104 LPDFVMCRAELAPVLLGAIRDAWR
MAB_2115|M.abscessus_ATCC_1997 LPDLIMCRPDLAPVLLDAVAGRA-
TH_2245|M.thermoresistible__bu LPDILVCRPELADAVLSAISAC--
***:::** ::* :* :