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M. leprae Br4923 MLBr_01301 (-)

annotation: putative inositol monophosphatase family protein
coordinates: 1549242 - 1550057
length: 271

MASHDKRDYQAELTDAALAADLATAAGELLLEIREEIGFDQPRALGDAGDRLANSLLLSRLRAERPGDAV
LSEEAHDDRVRLQAGRVWIIDPLDGTREFSTAGRTDWAVHIALWQRTTGGVADGRREITDAAVALPARGN
RVYRSDTVTAGAVTGGVPNILRIAVSATRPPTILHRIRQKLAIEPVAIGSAGAKAMAVVDGDVDAYLHVG
GQWEWDSAAPAGVVLAAGMHASRLDGSPLRYNQLDPYLPDFVMCRADIAPILLGVIREVWQ
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_01301--100% (271)putative inositol monophosphatase family protein
M. leprae Br4923MLBr_01024suhB9e-0831.47% (197) putative inositol monophosphatase
M. leprae Br4923MLBr_00662-5e-0634.19% (117) putative monophosphatase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2155ccysQ1e-11677.27% (264) hypothetical protein Mb2155c
M. gilvum PYR-GCKMflv_3047-2e-8564.20% (257) inositol monophosphatase
M. tuberculosis H37RvRv2131ccysQ1e-11677.27% (264) monophosphatase CysQ
M. abscessus ATCC 19977MAB_2115-5e-8562.20% (254) inositol monophosphatase CysQ
M. marinum MMMAR_3112cysQ1e-11376.45% (259) monophosphatase CysQ
M. avium 104MAV_2360-1e-11676.23% (265) inositol monophosphatase family protein
M. smegmatis MC2 155MSMEG_4190-2e-8665.22% (253) inositol monophosphatase family protein
M. thermoresistible (build 8)TH_2245cysQ1e-6150.39% (254) POSSIBLE MONOPHOSPHATASE CYSQ
M. ulcerans Agy99MUL_2362cysQ1e-11276.06% (259) monophosphatase CysQ
M. vanbaalenii PYR-1Mvan_3479-8e-8565.61% (253) inositol monophosphatase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3047|M.gilvum_PYR-GCK          MARVLTWSTDRVSITDAALAAAVAEEAGELLLAMREQIG--FYDPYDLGD
Mvan_3479|M.vanbaalenii_PYR-1       -----------MILTDAALAAAVAEEAGELLLAMRERIGADFYDAYDLGD
MSMEG_4190|M.smegmatis_MC2_155      -----------MTSTDAELAAAVAKEAGELLLGIREEVG--FYDPYYLGD
Mb2155c|M.bovis_AF2122/97           -MVSPAAPDLTDDLTDAELAADLAADAGKLLLQVRAEIG--FDQPWTLGE
Rv2131c|M.tuberculosis_H37Rv        -MVSPAAPDLTDDLTDAELAADLAADAGKLLLQVRAEIG--FDQPWTLGE
MLBr_01301|M.leprae_Br4923          -MASHDKRDYQAELTDAALAADLATAAGELLLEIREEIG--FDQPRALGD
MMAR_3112|M.marinum_M               -MS----HSPARHLTDAELAADLAVDAGKLLLAVREEVG--FDHPWALGD
MUL_2362|M.ulcerans_Agy99           -MS----HPPARHLTDAELAADLAVDAGKLLLAVREEVG--FDLPWALGD
MAV_2360|M.avium_104                -MTP---RNPSDEMTDAALAADLAAEAGELLLKVRDEVG--FGYPWALGD
MAB_2115|M.abscessus_ATCC_1997      -----------MTVSDAALAAELAHEAGQLLLQVRTELG--FDDPKGLGA
TH_2245|M.thermoresistible__bu      -------------VNDHELAAGLAARAGDLLLTVRTELAD--AAASERKD
                                                  .*  *** :*  **.*** :* .:.     .     

Mflv_3047|M.gilvum_PYR-GCK          AGDSRANTLILDRLRAARPGDAILSEEAVDDPSRVDADRVWIVDPVDGTY
Mvan_3479|M.vanbaalenii_PYR-1       AGDKRANTLILDRLHRERPHDAVLSEEAVDDLSRVDADRVWIVDPVDGTH
MSMEG_4190|M.smegmatis_MC2_155      EGDRRSNALILKRLAEARPSDSVLSEEAADNLARVRADRVWIVDPVDGTR
Mb2155c|M.bovis_AF2122/97           AGDRQANSLLLRRLQAERPGDAVLSEEAHDDLARLKSDRVWIIDPLDGTR
Rv2131c|M.tuberculosis_H37Rv        AGDRQANSLLLRRLQAERPGDAVLSEEAHDDLARLKSDRVWIIDPLDGTR
MLBr_01301|M.leprae_Br4923          AGDRLANSLLLSRLRAERPGDAVLSEEAHDDRVRLQAGRVWIIDPLDGTR
MMAR_3112|M.marinum_M               AGDFQANSLLLRRLRAERPGDAVLSEEAHDDLVRLKSDRVWIIDPLDGTR
MUL_2362|M.ulcerans_Agy99           AGDFQANSLLLRRLRAERPGDAVLSEEAHDDLVRLKSDRVWIIDPLDGTR
MAV_2360|M.avium_104                AGDSLANALILGRLQAERPDDAVLSEEAYDDLSRLQHDRVWIIDPLDGTR
MAB_2115|M.abscessus_ATCC_1997      AGDKRSNTLLLERLAAERPADAVLSEEAVDDKARLGAQRVWIIDPLDGTR
TH_2245|M.thermoresistible__bu      AGDKRSHDFLMAELARLRSGDAVLSEEGADDPARLTSDRVWIVDPLDGTR
                                     **  :: ::: .*   *. *::****. *:  *:   ****:**:*** 

Mflv_3047|M.gilvum_PYR-GCK          EYSMPGRADWAVHIALWRRD-------AGTLTDAAVALPARG-EVYRTDT
Mvan_3479|M.vanbaalenii_PYR-1       EYSMPGRADWAVHIALWQRAPRT---GAPTITDAAVALPARG-EVYRTDT
MSMEG_4190|M.smegmatis_MC2_155      EFSMPGREDWAVHIALWQRSVG----VDGGLSDAVVALPARG-EVYRSDT
Mb2155c|M.bovis_AF2122/97           EFSTPGRDDWAVHIALWRRSS----NGQPEITDAAVALPARGNVVYRTDT
Rv2131c|M.tuberculosis_H37Rv        EFSTPGRDDWAVHIALWRRSS----NGQPEITDAAVALPARGNVVYRTDT
MLBr_01301|M.leprae_Br4923          EFSTAGRTDWAVHIALWQRTTGGVADGRREITDAAVALPARGNRVYRSDT
MMAR_3112|M.marinum_M               EFSTRGRDDWAVHVALWQRRA----NGRPEITDAAVSLPARGNIVFRSDT
MUL_2362|M.ulcerans_Agy99           EFSTRGRDDWAVHVALWQRRA----NGRPEITDAAVSLPARGNIVFRSDT
MAV_2360|M.avium_104                EFSTPGRDDWAVHVALWQRPT----NGRREITDAAVSLPARGNIVYRSDT
MAB_2115|M.abscessus_ATCC_1997      EFGMEGRNDWAVHVALWQADG-----DGGSITDAAVALPGLD-TVFRTDE
TH_2245|M.thermoresistible__bu      EFSEPGRDDWAVHVALWAGGT---------LAAGAVALPAQG-VTLATPD
                                    *:.  ** *****:***             :: ..*:**. .  .  :  

Mflv_3047|M.gilvum_PYR-GCK          VAP--PPPRVDGPIRITASSNRPPAVLWHIRDELDIELYRIGSAGAKAMA
Mvan_3479|M.vanbaalenii_PYR-1       VTP--PPPRAEGPIRVTASSNRPPAVLWRLREQLDIELVRIGSAGAKAMA
MSMEG_4190|M.smegmatis_MC2_155      ITP--PPPREPGPILITASSNRPPAVLWRMREHLDFRMVRIGSAGAKAMA
Mb2155c|M.bovis_AF2122/97           VTSGAAPAGVPGTLRIAVSATRPPAVLHRIRQTLAIQPVSIGSAGAKAMA
Rv2131c|M.tuberculosis_H37Rv        VTSGAAPAGVPGTLRIAVSATRPPAVLHRIRQTLAIQPVSIGSAGAKAMA
MLBr_01301|M.leprae_Br4923          VTAGAVTGGVPNILRIAVSATRPPTILHRIRQKLAIEPVAIGSAGAKAMA
MMAR_3112|M.marinum_M               VTADAAPVGVPDVIRVAVSTTRPPAILYHVSRTLAIQPVAIGSAGAKAMA
MUL_2362|M.ulcerans_Agy99           VTADAAPVGVPDVIRVAVSTTRPPAILYHVSRTLAIQPVAIGSAGAKAMA
MAV_2360|M.avium_104                VTASAARVGVTDTIRIAVSATRPPAVLHRMRQRLPIQPVAIGSAGAKAMA
MAB_2115|M.abscessus_ATCC_1997      TRVTAAARAEADPIRIVASASRAPKFLTDMAERLNIELIPMGSAGAKAMA
TH_2245|M.thermoresistible__bu      VSAPPPAAAQP---RIVVSRTRPPALALTVRDALNGTLVEMGSAGAKVAA
                                                   :..* .*.* .   :   *      :******. *

Mflv_3047|M.gilvum_PYR-GCK          VVRGDVDAYLHAGGQWEWDSAAPAGVLWAAGLHASRLDGSPLIYNRPDPY
Mvan_3479|M.vanbaalenii_PYR-1       VVRGDVDAYLHAGGQWEWDSAAPAGVLWAAGMHASRIDGSPLIYNRRDPY
MSMEG_4190|M.smegmatis_MC2_155      VVRGDVDAYIHAGGQWEWDSAAPAGVLLAAGMHASRLDGSELRYNREDPY
Mb2155c|M.bovis_AF2122/97           VIDGYVDAYLHAGGQWEWDSAAPAGVMLAAGMHASRLDGSPLRYNQLDPY
Rv2131c|M.tuberculosis_H37Rv        VIDGYVDAYLHAGGQWEWDSAAPAGVMLAAGMHASRLDGSPLRYNQLDPY
MLBr_01301|M.leprae_Br4923          VVDGDVDAYLHVGGQWEWDSAAPAGVVLAAGMHASRLDGSPLRYNQLDPY
MMAR_3112|M.marinum_M               LIEGKADAYLHAGGQWEWDSAAPAGVVMAAGMHASRLDGSPLRYNQLDPY
MUL_2362|M.ulcerans_Agy99           LIEGKADAYLHAGGQWEWDSAAPAGVVMASGMHASRLDGSPLRYNQLDPY
MAV_2360|M.avium_104                IIDGVVDAYLHAGGQWEWDSAAPAGVVMAAGMHASRLDGSPMRYNQLDPY
MAB_2115|M.abscessus_ATCC_1997      VVRGEADAYLHGGGQWEWDSAAPAGVVLAAGLHASRLDGSPLRYNEPHPY
TH_2245|M.thermoresistible__bu      VVQGRADVYVHAGGQYEWDNAAPAAVAVAAGLHTSRIDGSPLRYNNPDPR
                                    :: * .*.*:* ***:***.****.*  *:*:*:**:*** : **. .* 

Mflv_3047|M.gilvum_PYR-GCK          LPDLLMCRPEVAGRLLDVIWSAYR
Mvan_3479|M.vanbaalenii_PYR-1       LPDLLMCRPEVAGVLLEGIWSAYR
MSMEG_4190|M.smegmatis_MC2_155      LPDFVMCRRELAPVLLDAIGAAL-
Mb2155c|M.bovis_AF2122/97           LPDLLMCRAEVAPILLGAIADAWR
Rv2131c|M.tuberculosis_H37Rv        LPDLLMCRAEVAPILLGAIADAWR
MLBr_01301|M.leprae_Br4923          LPDFVMCRADIAPILLGVIREVWQ
MMAR_3112|M.marinum_M               LPDFVMCRPELAPVLLDAIRQVWR
MUL_2362|M.ulcerans_Agy99           LPDFVMCRPELAPVLLDAIRQVWR
MAV_2360|M.avium_104                LPDFVMCRAELAPVLLGAIRDAWR
MAB_2115|M.abscessus_ATCC_1997      LPDLIMCRPDLAPVLLDAVAGRA-
TH_2245|M.thermoresistible__bu      LPDILVCRPELADAVLSAISAC--
                                    ***:::** ::*  :*  :