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VTDDHELAGRLATAAGALLLDVRAELAEATPEERKAAGDKRAHDFLLAALTAERPEDAVLSEEGVDDPVR LSAQRVWIVDPLDGTREFSELGRTDWAVHVALWERTGSGGELVAGAVALPAQGVTLVTPTVVAPPAGPSS PRVVVSRTRPPAVALDVKDALNGTLVEMGSAGAKVASVVQGLSDVYVHAGGQYEWDSAAPVAVARAAGLH TSRIDGSPLVYNQRDSKLPDLIVCRPELADAVLAVTTR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2273 | - | - | 100% (248) | inositol monophosphatase |
| M. gilvum PYR-GCK | Mflv_3047 | - | 1e-66 | 53.91% (243) | inositol monophosphatase |
| M. gilvum PYR-GCK | Mflv_4454 | - | 4e-06 | 33.85% (130) | histidinol-phosphate phosphatase, putative |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2155c | cysQ | 2e-67 | 56.73% (245) | hypothetical protein Mb2155c |
| M. tuberculosis H37Rv | Rv2131c | cysQ | 2e-67 | 56.73% (245) | monophosphatase CysQ |
| M. leprae Br4923 | MLBr_01301 | - | 4e-66 | 53.78% (251) | putative inositol monophosphatase family protein |
| M. abscessus ATCC 19977 | MAB_2115 | - | 2e-68 | 55.97% (243) | inositol monophosphatase CysQ |
| M. marinum M | MMAR_3456 | cysQ_1 | 1e-104 | 77.05% (244) | monophosphatase CysQ_1 |
| M. avium 104 | MAV_2129 | - | 1e-109 | 80.74% (244) | 3'(2'),5'-bisphosphate nucleotidase, putative |
| M. smegmatis MC2 155 | MSMEG_4977 | - | 1e-103 | 76.64% (244) | 3'(2'),5'-bisphosphate nucleotidase, putative |
| M. thermoresistible (build 8) | TH_2245 | cysQ | 5e-99 | 74.79% (242) | POSSIBLE MONOPHOSPHATASE CYSQ |
| M. ulcerans Agy99 | MUL_2730 | cysQ_1 | 1e-102 | 76.23% (244) | monophosphatase CysQ_1 |
| M. vanbaalenii PYR-1 | Mvan_4421 | - | 1e-121 | 87.80% (246) | inositol monophosphatase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2273|M.gilvum_PYR-GCK -----------MTDDHELAGRLATAAGALLLDVRAELAEATPEERKAAGD
Mvan_4421|M.vanbaalenii_PYR-1 -----------MTDDHALAAQLATEAGELLLDVRSELAGAPAEERKAAGD
MMAR_3456|M.marinum_M ------------MNDHAVAAWLATEAGRLLLGVREEFAEAEVAQRKAAGD
MUL_2730|M.ulcerans_Agy99 ------------MNDHAVAAWLATEAGRLLLGVREEFAAAEGAQRKAAGD
MAV_2129|M.avium_104 ------------MNDHELAARLATEAGRLLLGVRDEFADAPASERKAAGD
MSMEG_4977|M.smegmatis_MC2_155 ------------MNDHELAARLATRAGDLLLDVRADFADAPAQDRKAAGD
TH_2245|M.thermoresistible__bu ------------VNDHELAAGLAARAGDLLLTVRTELADAAASERKDAGD
Mb2155c|M.bovis_AF2122/97 MVSPAAPDLTDDLTDAELAADLAADAGKLLLQVRAEIGFDQPWTLGEAGD
Rv2131c|M.tuberculosis_H37Rv MVSPAAPDLTDDLTDAELAADLAADAGKLLLQVRAEIGFDQPWTLGEAGD
MLBr_01301|M.leprae_Br4923 MASHDKRDYQAELTDAALAADLATAAGELLLEIREEIGFDQPRALGDAGD
MAB_2115|M.abscessus_ATCC_1997 ----------MTVSDAALAAELAHEAGQLLLQVRTELGFDDPKGLGAAGD
* :*. ** ** *** :* ::. ***
Mflv_2273|M.gilvum_PYR-GCK KRAHDFLLAALTAERPEDAVLSEEGVDDPVRLSAQRVWIVDPLDGTREFS
Mvan_4421|M.vanbaalenii_PYR-1 KRSHDFLLAVLTAERPDDAVLSEEGVDDPVRLSARRVWIVDPLDGTREFS
MMAR_3456|M.marinum_M KRSHDFLMDKLAAERPGDAVLSEEGADDPVRLCSERVWIVDPLDGTREFS
MUL_2730|M.ulcerans_Agy99 KRSHDFLMDKLAAERPGDAVLSEEGADDPVRLRSERVWIVDPLDGTREFS
MAV_2129|M.avium_104 KRSHDFLIEALAAERPGDAVLSEEGADDPVRLRSERVWIVDPLDGTREFS
MSMEG_4977|M.smegmatis_MC2_155 KQSHDFLMAELARQRPGDAVLSEEGVDDPARLDAERVWIVDPLDGTREFS
TH_2245|M.thermoresistible__bu KRSHDFLMAELARLRSGDAVLSEEGADDPARLTSDRVWIVDPLDGTREFS
Mb2155c|M.bovis_AF2122/97 RQANSLLLRRLQAERPGDAVLSEEAHDDLARLKSDRVWIIDPLDGTREFS
Rv2131c|M.tuberculosis_H37Rv RQANSLLLRRLQAERPGDAVLSEEAHDDLARLKSDRVWIIDPLDGTREFS
MLBr_01301|M.leprae_Br4923 RLANSLLLSRLRAERPGDAVLSEEAHDDRVRLQAGRVWIIDPLDGTREFS
MAB_2115|M.abscessus_ATCC_1997 KRSNTLLLERLAAERPADAVLSEEAVDDKARLGAQRVWIIDPLDGTREFG
: :: :*: * *. *******. ** .** : ****:*********.
Mflv_2273|M.gilvum_PYR-GCK ELGRTDWAVHVALWERTG-----SGGELVAGAVALPAQGVTLVTPTVVAP
Mvan_4421|M.vanbaalenii_PYR-1 ELGRTDWAVHVALWERNG-----SSGELVAGAVALPAQGATLATPTVPAP
MMAR_3456|M.marinum_M ELGRVDWAVHVALWQ---------AGQLVAGAVALPAQGITLATPHVEPP
MUL_2730|M.ulcerans_Agy99 ELGRVDWAVHVALWQ---------AGQLVAGAVALPAQDITLATPHVEPP
MAV_2129|M.avium_104 ELGRDDWAVHVALWE---------AGELVAGAVALPAQGVTFATPEVASP
MSMEG_4977|M.smegmatis_MC2_155 ELGREDWAVHVALWQ---------AGELVAGAVALPAQNMTLSTPEVAGP
TH_2245|M.thermoresistible__bu EPGRDDWAVHVALWA---------GGTLAAGAVALPAQGVTLATPDVSAP
Mb2155c|M.bovis_AF2122/97 TPGRDDWAVHIALWRRSS----NGQPEITDAAVALPARGNVVYRTDTVTS
Rv2131c|M.tuberculosis_H37Rv TPGRDDWAVHIALWRRSS----NGQPEITDAAVALPARGNVVYRTDTVTS
MLBr_01301|M.leprae_Br4923 TAGRTDWAVHIALWQRTTGGVADGRREITDAAVALPARGNRVYRSDTVTA
MAB_2115|M.abscessus_ATCC_1997 MEGRNDWAVHVALWQADG----DGGS-ITDAAVALPG-LDTVFRTDETRV
** *****:*** :. .*****. . .
Mflv_2273|M.gilvum_PYR-GCK PAG----PSSPRVVVSRTRPPAVALDVKDALNGTLVEMGSAGAKVASVVQ
Mvan_4421|M.vanbaalenii_PYR-1 PAG----PGAPRVVVSRTRPPAVALAVKEALGGTLIEMGSAGAKVASVVQ
MMAR_3456|M.marinum_M PAA----PDRPRIVVSRTRPPAIALAVRDALDGTLVEMGSAGAKVASVVQ
MUL_2730|M.ulcerans_Agy99 PAA----PDRPRIVVSRTRPPAIALAVRDALDGTLVEMGSAGAKVASVVQ
MAV_2129|M.avium_104 PVA----PGKPRIVVSRTRPPAIALNVRDALDGVLVEMGSAGAKVASVVQ
MSMEG_4977|M.smegmatis_MC2_155 LPL----EGPPRVVVSRTRPPAIALAVRDALDGTLVEMGSAGAKVAAVIR
TH_2245|M.thermoresistible__bu PPA----AAQPRIVVSRTRPPALALTVRDALNGTLVEMGSAGAKVAAVVQ
Mb2155c|M.bovis_AF2122/97 GAAPAGVPGTLRIAVSATRPPAVLHRIRQTLAIQPVSIGSAGAKAMAVID
Rv2131c|M.tuberculosis_H37Rv GAAPAGVPGTLRIAVSATRPPAVLHRIRQTLAIQPVSIGSAGAKAMAVID
MLBr_01301|M.leprae_Br4923 GAVTGGVPNILRIAVSATRPPTILHRIRQKLAIEPVAIGSAGAKAMAVVD
MAB_2115|M.abscessus_ATCC_1997 TAAARAEADPIRIVASASRAPKFLTDMAERLNIELIPMGSAGAKAMAVVR
*:..* :*.* . : : * : :******. :*:
Mflv_2273|M.gilvum_PYR-GCK GLSDVYVHAGGQYEWDSAAPVAVARAAGLHTSRIDGSPLVYNQRDSKLPD
Mvan_4421|M.vanbaalenii_PYR-1 GLADVYVHAGGQYEWDSAAPVAVARAAGLHTSRIDGSPLVYNRRDPLLPD
MMAR_3456|M.marinum_M GLADVYVHAGGQFEWDSAAPVAVARSAGLHTSRIDGSALTYNRPDPKLPD
MUL_2730|M.ulcerans_Agy99 GLADVYVHAGGQFEWDSAAPVAVARSAGLHTSRIDGSALTYNRPDPKLPD
MAV_2129|M.avium_104 GLSDVYVHAGGQFEWDSAAPVAVARAAGLHTSRIDGSALAYNQPDPKLPD
MSMEG_4977|M.smegmatis_MC2_155 GHADVYVHAGGQYEWDSAAPVAVARAAGMHTSRIDGSPLRYNARDPRLPD
TH_2245|M.thermoresistible__bu GRADVYVHAGGQYEWDNAAPAAVAVAAGLHTSRIDGSPLRYNNPDPRLPD
Mb2155c|M.bovis_AF2122/97 GYVDAYLHAGGQWEWDSAAPAGVMLAAGMHASRLDGSPLRYNQLDPYLPD
Rv2131c|M.tuberculosis_H37Rv GYVDAYLHAGGQWEWDSAAPAGVMLAAGMHASRLDGSPLRYNQLDPYLPD
MLBr_01301|M.leprae_Br4923 GDVDAYLHVGGQWEWDSAAPAGVVLAAGMHASRLDGSPLRYNQLDPYLPD
MAB_2115|M.abscessus_ATCC_1997 GEADAYLHGGGQWEWDSAAPAGVVLAAGLHASRLDGSPLRYNEPHPYLPD
* *.*:* ***:***.***..* :**:*:**:***.* ** .. ***
Mflv_2273|M.gilvum_PYR-GCK LIVCRPELADAVLAVTTR---
Mvan_4421|M.vanbaalenii_PYR-1 LIVCRPELAEAVLAVTAG---
MMAR_3456|M.marinum_M LVVCRPELATAVLAATG----
MUL_2730|M.ulcerans_Agy99 LVVCRPELATAVLAATG----
MAV_2129|M.avium_104 LVVCRPELADAVLAVTR----
MSMEG_4977|M.smegmatis_MC2_155 LIVCRPELAEQVLAVTRS---
TH_2245|M.thermoresistible__bu ILVCRPELADAVLSAISAC--
Mb2155c|M.bovis_AF2122/97 LLMCRAEVAPILLGAIADAWR
Rv2131c|M.tuberculosis_H37Rv LLMCRAEVAPILLGAIADAWR
MLBr_01301|M.leprae_Br4923 FVMCRADIAPILLGVIREVWQ
MAB_2115|M.abscessus_ATCC_1997 LIMCRPDLAPVLLDAVAGRA-
:::**.::* :* .