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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2204 | papA1 | - | 100% (483) | PROBABLE CONSERVED POLYKETIDE SYNTHASE ASSOCIATED PROTEIN PAPA1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1214 | papA3 | 1e-155 | 55.17% (464) | polyketide synthase associated protein PapA3 |
| M. gilvum PYR-GCK | Mflv_0404 | - | 1e-131 | 48.81% (463) | condensation domain-containing protein |
| M. tuberculosis H37Rv | Rv1182 | papA3 | 1e-155 | 55.17% (464) | polyketide synthase associated protein PapA3 |
| M. leprae Br4923 | MLBr_01230 | papA3 | 1e-157 | 54.45% (461) | PKS-associated protein, unknown function |
| M. abscessus ATCC 19977 | MAB_0938c | - | 1e-132 | 48.28% (466) | polyketide synthase associated protein PapA3 |
| M. marinum M | MMAR_2343 | - | 1e-169 | 59.74% (467) | hypothetical protein MMAR_2343 |
| M. avium 104 | MAV_1762 | - | 1e-136 | 49.24% (463) | condensation domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_4728 | - | 1e-150 | 54.53% (475) | condensation domain-containing protein |
| M. ulcerans Agy99 | MUL_1531 | papA3 | 1e-153 | 55.14% (477) | polyketide synthase associated protein PapA3 |
| M. vanbaalenii PYR-1 | Mvan_0270 | - | 1e-129 | 48.60% (463) | condensation domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
TH_2204|M.thermoresistible__bu ------------MVALGNVAVETVREWRPDPGRVVSWDPSPAALEKARQA
MMAR_2343|M.marinum_M ----------MKLVVLGNVGLETVSNWVPAPGLVWRWQPSSATLEKVRQA
MSMEG_4728|M.smegmatis_MC2_155 -----------------MFELTDIQNWDDAPGKHVSWGPSPSTVAKVAEA
MUL_1531|M.ulcerans_Agy99 ------------MVRVGKVEAGTISDWHPEPGTLVSWQPSRGSLAKAAKA
Mb1214|M.bovis_AF2122/97 ------------MLRVGPLTIGTLDDWAPSTGSTVSWRPSAVAHTKASQA
Rv1182|M.tuberculosis_H37Rv ------------MLRVGPLTIGTLDDWAPSTGSTVSWRPSAVAHTKASQA
MLBr_01230|M.leprae_Br4923 -------------MQVGPLTLGTLLDWAPRAGKTISWQPTPATCEKVSQA
Mflv_0404|M.gilvum_PYR-GCK -------------MRIGKITVGALEEWSLSPGKVISWHPTAASIEKARQA
Mvan_0270|M.vanbaalenii_PYR-1 -------------MRIGKITVGALDEWSLNPGSVTSWHPTAAAVETARRA
MAB_0938c|M.abscessus_ATCC_199 MPERGRPSERDGVLRIGTITVGALDEWTLNAGTVTSWHPTPAATEKARQA
MAV_1762|M.avium_104 -------------MRIGKITIGSLGDWTPTPGPVTSWHPTAAAAEKVRQA
. : :* .* * *: : .. .*
TH_2204|M.thermoresistible__bu PVSSVPVSYMQAQHLRGFVEHAARGQEMSRLCIAAFDIPGRCDLRAMTYV
MMAR_2343|M.marinum_M PVSAVPPSHIQARHLRGFAEQTARGHDMSRLVVAAMDIPGECDIRAMTYV
MSMEG_4728|M.smegmatis_MC2_155 PVSDVPASYQQAQHLRAYREHTARGVPMARLTVPVWNMDSQCDMRAMSHV
MUL_1531|M.ulcerans_Agy99 PISPVPPSYMQAHHLRNFRSYRERGLEMSRLLISSWDIPGICDIRTMTHV
Mb1214|M.bovis_AF2122/97 PISDVPVSYMQAQHIRGYCEQKAKGLDYSRLMVVSCQQPGQCDIRAANYV
Rv1182|M.tuberculosis_H37Rv PISDVPVSYMQAQHIRGYCEQKAKGLDYSRLMVVSCQQPGQCDIRAANYV
MLBr_01230|M.leprae_Br4923 PVSSVPVAYMQAQHIRGYVEQKAKGLDYSRLMIVSCDQLGQCDIRAINYI
Mflv_0404|M.gilvum_PYR-GCK PVSSVPVSYMQGQHLRNYCDRTTEGLNFSRQIIASCDVAGVCDIEAMDHA
Mvan_0270|M.vanbaalenii_PYR-1 QVSSVPVSYMQGQHLRNYWERTTAGLNFSRQIIASCEVPGQCDIAAMDHA
MAB_0938c|M.abscessus_ATCC_199 PVSSVPVSYMQTQHLRNYYERNNAGLNFSRQIIASCDVPGNCDIAAMNHA
MAV_1762|M.avium_104 PASPVPVSYMQGQHLRNYHERTAAGLDFSRQIIATCDVPGRCDISAMNYA
* ** :: * :*:* : . * :* : : . **: : :
TH_2204|M.thermoresistible__bu INAHMRRHDTYRSWFEYHDFHHIVRHTITDPADIELVPTRHGAMTPE-QW
MMAR_2343|M.marinum_M INSHLRRHDTYRSWFEFTESNRIARHTLTDPNDIELTPIEHGEMSPK-QW
MSMEG_4728|M.smegmatis_MC2_155 INAYLRRHDTYHSRFEFTVDDRIVRRKLRSPRDLRFVPTDHGVQTCD-QW
MUL_1531|M.ulcerans_Agy99 VNAHMRRHDTFRSWFEHTEGDHFVRRTLERPNDIQFVAVEHGELTTQSQW
Mb1214|M.bovis_AF2122/97 INAHLRRHDTYRSWFQYNGNGQIIRRTIQDPADIEFVPVHHGELTLP-QI
Rv1182|M.tuberculosis_H37Rv INAHLRRHDTYRSWFQYNGNGQIIRRTIQDPADIEFVPVHHGELTLP-QI
MLBr_01230|M.leprae_Br4923 VNAHLRRHDTYRSWFEYTDEGEIIRHTLCDPADIEFVPIEHGQLSLA-QI
Mflv_0404|M.gilvum_PYR-GCK VNAYLRRHDTFRSWFEHSGDGEFVRRALVDPEDIEFVPVEHGHMGVD-EI
Mvan_0270|M.vanbaalenii_PYR-1 VNAYLRRHDTFRSWFERTEEGEFLRRAIADPADIEFVPIEHGDMTVD-EI
MAB_0938c|M.abscessus_ATCC_199 LNAYLRRHDTFRSWFERTDDGEFIRHSISDPADIEFAPVTQGHMSVD-EI
MAV_1762|M.avium_104 VNAYLRRHDTFRSWFHHSGDGEFVRHTVSNPADIEFAPIHHGEMTAE-EI
:*:::*****::* *. .: *: : * *:.:.. :* :
TH_2204|M.thermoresistible__bu QQHLLSTPDPLQWNCFRFSIIQRSDHFTFCVCMDHVHIDAMFMGAVFMEI
MMAR_2343|M.marinum_M QDYILATPGPLEWDCFRFAIIQRDDHFTFCVSVDHLNVDAMFISAVFWEI
MSMEG_4728|M.smegmatis_MC2_155 REHILDTPGPLQWDCFRFGIIQRTDHFTCYMSVDHVHVDATFLGLMLIEI
MUL_1531|M.ulcerans_Agy99 RERLLATPSPLEWGCVRFSIIQRADHFTFCVAIDHLHCDAMFVGVVFAEI
Mb1214|M.bovis_AF2122/97 REIVQNTPDPLQWGCFRFGIVQGCDHFTFFASVDHVHVDAMIVGVTLMEF
Rv1182|M.tuberculosis_H37Rv REIVQNTPDPLQWGCFRFGIVQGCDHFTFFASVDHVHVDAMIVGVTLMEF
MLBr_01230|M.leprae_Br4923 RELAVSTPDPLEWGCFQFGVIQAEEHFTFYASIDHVHVDAMIVGVTLMEF
Mflv_0404|M.gilvum_PYR-GCK HAHVVAIPSPLEWGCFTFGVIQNDDHFSFFASMDHVHGDATLIGTTMMEA
Mvan_0270|M.vanbaalenii_PYR-1 FAHVVDIPSPLEWGCFTFGVIQHDGHFTFFASMDHVHGDATLIGTTMMEA
MAB_0938c|M.abscessus_ATCC_199 RSHVIDIPSPLEWGCFTFGIIQSENHFTFFAAMDHVHGDATLIGTTMMEA
MAV_1762|M.avium_104 RAHVVAIPNPLEWGCFTFGVVQNEEYFTFFAAMDHVHGDATLIGTTMLEA
*.**:*.*. *.::* :*: .:**:: ** ::. : *
TH_2204|M.thermoresistible__bu HMQYAALVGGGAPIPL-QAGSYDDFCVRQRQYTESLTADSPEVRAWVDFA
MMAR_2343|M.marinum_M EAMYNTLADGGAPISLPEAGSYGEYCLRERAYTSALTLESPEVRQWIDFF
MSMEG_4728|M.smegmatis_MC2_155 HLMYAALVSGGAPITLPPAGSYDDYCVRQRKYTSGLTLDSPEIKEWVTFL
MUL_1531|M.ulcerans_Agy99 HLMYLALVSGGAPLRLAEPGSYDNYCNRQREHISGLTLDSPVMSKWTEFF
Mb1214|M.bovis_AF2122/97 HLMYAALVGGHAPLELPPAGSYDDFCRRQHTFSSTLTVESPQVRAWTKFA
Rv1182|M.tuberculosis_H37Rv HLMYAALVGGHAPLELPPAGSYDDFCRRQHTFSSTLTVESPQVRAWTKFA
MLBr_01230|M.leprae_Br4923 HMMYSALVSGAGPLELPEAGSYDDFCRRQHRFTSMLTAESPQIRSWTQFA
Mflv_0404|M.gilvum_PYR-GCK NGMYSALSSGGAALALPDAGSFDDFCVREREYTAELTEDSPGVRAWIEFA
Mvan_0270|M.vanbaalenii_PYR-1 NGMYSALSGGGAALTLPDAGSFDEFCVRERAHTSELTEDSPEVRAWIEFA
MAB_0938c|M.abscessus_ATCC_199 NGMYSALSSGGAALTLPDAGSFDDFCTREREFTSALTLDSPGVQAWIDFA
MAV_1762|M.avium_104 NGMYAAASAGSEPLELPDAGSFDDFCAREREYTSALTVDSPEVRAWIDFA
. * : * .: * .**:.::* *:: . ** :** : * *
TH_2204|M.thermoresistible__bu GQMGGTLPNFPLPLGDRTKPWPGELMVVKLLDGRQTDRFEAACVSAGARF
MMAR_2343|M.marinum_M ESNDGALPSFPLPLGDLSLVDTGELLSLQLMDAGQTARFEAACTSAGARF
MSMEG_4728|M.smegmatis_MC2_155 EGNNGTMPKFPLPLGDLSVPCTGDLMTVQLLDEPQTQGFEKACVAAGSRF
MUL_1531|M.ulcerans_Agy99 DNNDGSLPKFPLPLGDTSAQC--EMMGVRLMDERQTLALEAACMSAGARF
Mb1214|M.bovis_AF2122/97 EGTNGSFPDFPLPLGDPSKPSDADIVTVMMLDEEQTAQFESVCTAAGARF
Rv1182|M.tuberculosis_H37Rv EGTNGSFPDFPLPLGDPSKPSDADIVTVMMLDEEQTAQFESVCTAAGARF
MLBr_01230|M.leprae_Br4923 EPNEGSFPDFPLPLGDPLEPTQADIVTITMLDEQQTDRFEAACTVAGARF
Mflv_0404|M.gilvum_PYR-GCK ENNSDGFPEFPLPLGNPKDSTRSVMTSAVLMDTAQTERFDAAATAAGARF
Mvan_0270|M.vanbaalenii_PYR-1 ENSGGGFPEFPLPLGNPAESTRSCMTSEILMDTAQTERFESACTAAGARF
MAB_0938c|M.abscessus_ATCC_199 ENNNGTFPEFPLPLGNPAEATNSTMTSLLLLNPEQTDRFDAACGTAGARF
MAV_1762|M.avium_104 ENNNGSFPEFPLPLGNPSEATASAMVSELVMDAEQTERFESACTAVGVRF
. :*.******: : ::: ** :: .. .* **
TH_2204|M.thermoresistible__bu VGGVFACAALTENELAGVETFHAITPTDTRSTPADFMTTGWFTGMVPITV
MMAR_2343|M.marinum_M SGGVFACAALAEYELTGSRTYYAVTPTSTRSTPAEFMTTGWFVGHIPFTV
MSMEG_4728|M.smegmatis_MC2_155 IGGVFAAAALAQYQLTDIDTYHVITPTTTRGTEAEVMATGWFTGTVPITV
MUL_1531|M.ulcerans_Agy99 CGGVFAISAVVQHELTGADEYYAIVPIDIRRTEEDFMTTGWFTGFVPITV
Mb1214|M.bovis_AF2122/97 IGGVLACCGLAEHELTGTTTYYGLTPRDTRRTPADAMTQGWFTGLIPITV
Rv1182|M.tuberculosis_H37Rv IGGVLACCGLAEHELTGTTTYYGLTPRDTRRTPADAMTQGWFTGLIPITV
MLBr_01230|M.leprae_Br4923 VGGVLACCGLAEYELTGADTYYGLTPRDTRRIPTDVLTQGWFTGLVPITV
Mflv_0404|M.gilvum_PYR-GCK VGGLFACLAQVEHELTGALTYYGLTPRDSRSGSDNFMTQGWFTGLIPITV
Mvan_0270|M.vanbaalenii_PYR-1 VGGLFACLAQVEHELTGALTYYGLTPRDSRSASDNFMTQGWFTGLIPITV
MAB_0938c|M.abscessus_ATCC_199 VGGLFACLGLVEHEFTGAVTYYGLTPRDSRTASDNFMTQGWFTGLIPITV
MAV_1762|M.avium_104 IGGLFACIALVEHELTGALTYYGLTPRDTRRTTDNFMTQGWFTGLVPITV
**::* . .: :::. :: :.* * : :: ***.* :*:**
TH_2204|M.thermoresistible__bu PAAGVSFGEAARAAQQSFDSGIGLGHVPYDRVLELVPSLR--RAETCS--
MMAR_2343|M.marinum_M AVA-SSFDETVRGAQANFDASAHLANVPFERVLELAPWLK--KPPPRGGF
MSMEG_4728|M.smegmatis_MC2_155 PVG-SSFAETARTAQRSFDSGLYLAHVPFDRVLELGATERGLRAPDPG-V
MUL_1531|M.ulcerans_Agy99 PTVGSSFGEIVKAAQGSFDSGRDLAEVPLDCVMELVLWLR---EGQWG-A
Mb1214|M.bovis_AF2122/97 PIAGSAFGDAARAAQTSFDSGVKLAEVPYDRVVELSSTLT---MPRPN-F
Rv1182|M.tuberculosis_H37Rv PIAGSAFGDAARAAQTSFDSGVKLAEVPYDRVVELSSTLT---MPRPN-F
MLBr_01230|M.leprae_Br4923 PIAGSSFGDAARAAQNCFDTDVHLAEVPYDRVVELAPTVH---KPRPN-F
Mflv_0404|M.gilvum_PYR-GCK PIGAASFGEAAWAAQSSFDSGLNMAKVPYYRVLELAPWLG---WPRPN-F
Mvan_0270|M.vanbaalenii_PYR-1 PIGATSFADAAWAAQASFDSNLFMAKVPYYRVLELAPWLS---WPRPN-F
MAB_0938c|M.abscessus_ATCC_199 PIAATSFNDAAYAAQTAFDSSLDMARVPYYRVLELAPWLK---WPEPN-F
MAV_1762|M.avium_104 PIAAASFADAAWTAQTSFDSGQQLAKVPYYRVLELAPWLK---WPQPN-F
. :* : . ** **:. :..** *:** .
TH_2204|M.thermoresistible__bu PMMSFLDAGVPPLSALVASQLDG--LNARVYGDGKVPAQLCMWVNRMDNE
MMAR_2343|M.marinum_M PMVSFLDGGVPPLSGVVAMQLDR--INARAFSDGRVAARVCIWVNKFQEE
MSMEG_4728|M.smegmatis_MC2_155 PMVSYLDATAAPLSPAVVAEWNR--INGRIFSEMGAANQVGMWVNQFGSG
MUL_1531|M.ulcerans_Agy99 PLLFYLDAGIPPLSAMANSHVEG--LRARLCHDGGMMGQIDIRVNRLEKE
Mb1214|M.bovis_AF2122/97 PVVNFLDAGAAPLSVLLTAELTG--TNIGVYSDGRYSYQLSIYVIRVEQG
Rv1182|M.tuberculosis_H37Rv PVVNFLDAGAAPLSVLLTAELTG--TNIGVYSDGRYSYQLSIYVIRVEQG
MLBr_01230|M.leprae_Br4923 PVINFLDAGTAPLSVLLTAGLDG--LNIGVYSDGRYSYQMSIYVIRVEQE
Mflv_0404|M.gilvum_PYR-GCK PVSNFFHGGAAPLNAILAASEMGLADNIGIYPDGRFSYQLTIYIFRYGQG
Mvan_0270|M.vanbaalenii_PYR-1 PVSNFFHGGAAPLNAILAAADMGLANNIGIYPDGRFSYQLTIYIFRYGEG
MAB_0938c|M.abscessus_ATCC_199 PVSNFFHGGAAPLNAILAAGELGLADNIGIYPDGRFSYQLTIYIFRYGEG
MAV_1762|M.avium_104 PVSNFFHAGAAPLNAVLAAADLGYANNIGIYSDGRYSYQLTIYVFRYGEG
*: ::.. .**. . : :: : : : .
TH_2204|M.thermoresistible__bu TSVTVFFPDNPVARASVEKYVATLRSIYVAVAEGRADRLGARRSG-ELQR
MMAR_2343|M.marinum_M TTVTASFPNNPIAYDSVARYLDTMKSVYLRIAEG------ARWDA-IAQV
MSMEG_4728|M.smegmatis_MC2_155 TWITVAFPNNPVARASVQEYVDAFRSVCVAVAEGRHDDVPTPRVN-ELDL
MUL_1531|M.ulcerans_Agy99 TQLTVLFPNNPVARESVTRYVEALKSAFVRVAEGRDVMPAPSRTGSQLHL
Mb1214|M.bovis_AF2122/97 TAVAVMFPDNPIARESVARYLATLKSVFQRVAESGQQQNVA---------
Rv1182|M.tuberculosis_H37Rv TAVAVMFPDNPIARESVARYLATLKSVFQRVAESGQQQNVA---------
MLBr_01230|M.leprae_Br4923 TAVAVMFPDNPEAQESVARYLETLKSVFECVAESGHWRNVA---------
Mflv_0404|M.gilvum_PYR-GCK TEMAIMHPDNPVAKRSVERYMQTMSSVASLVADTGHWGRVA---------
Mvan_0270|M.vanbaalenii_PYR-1 TVMAIMHPDNPVAKKSVTRYMKVMKSVAGLVADSGTWGLVA---------
MAB_0938c|M.abscessus_ATCC_199 TAMAIMHPDNPIAEKSALRYMEAMKSVCARVADTGHWGRVA---------
MAV_1762|M.avium_104 TAMAMMYPDNPVAHKSVARYTETMRSVCGRVADTGHWGRVA---------
* :: .*:** * *. .* .: * :*: .
TH_2204|M.thermoresistible__bu QPA-------------------
MMAR_2343|M.marinum_M L---------------------
MSMEG_4728|M.smegmatis_MC2_155 RSA-------------------
MUL_1531|M.ulcerans_Agy99 AYSRRTYEPPATVSPLTSWRTG
Mb1214|M.bovis_AF2122/97 ----------------------
Rv1182|M.tuberculosis_H37Rv ----------------------
MLBr_01230|M.leprae_Br4923 ----------------------
Mflv_0404|M.gilvum_PYR-GCK ----------------------
Mvan_0270|M.vanbaalenii_PYR-1 ----------------------
MAB_0938c|M.abscessus_ATCC_199 ----------------------
MAV_1762|M.avium_104 ----------------------