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M. thermoresistible (build 8) TH_2114 (ephC)

annotation: PROBABLE EPOXIDE HYDROLASE EPHC (EPOXIDE HYDRATASE)
coordinates: 4153405 - 4154316
length: 304

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2114ephC-100% (304)PROBABLE EPOXIDE HYDROLASE EPHC (EPOXIDE HYDRATASE)
M. thermoresistible (build 8)TH_0992ephA6e-1929.91% (321) PROBABLE EPOXIDE HYDROLASE EPHA (EPOXIDE HYDRATASE)
M. thermoresistible (build 8)TH_0963ephE5e-1426.69% (311) POSSIBLE EPOXIDE HYDROLASE EPHE (EPOXIDE HYDRATASE)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1155ephC1e-12166.89% (302) epoxide hydrolase EphC
M. gilvum PYR-GCKMflv_0191-4e-7747.52% (303) alpha/beta hydrolase fold
M. tuberculosis H37RvRv1124ephC1e-12166.89% (302) epoxide hydrolase EphC
M. leprae Br4923MLBr_02297-9e-0927.24% (301) putative hydrolase
M. abscessus ATCC 19977MAB_4573c-6e-6142.09% (297) epoxide hydrolase EphC
M. marinum MMMAR_4334ephC1e-12370.23% (299) epoxide hydrolase EphC
M. avium 104MAV_1256-1e-11766.78% (304) hydrolase, alpha/beta fold family protein
M. smegmatis MC2 155MSMEG_1998-8e-6144.04% (302) hydrolase, alpha/beta fold family protein
M. ulcerans Agy99MUL_0144ephC1e-12370.23% (299) epoxide hydrolase EphC
M. vanbaalenii PYR-1Mvan_0714-4e-7346.20% (303) alpha/beta hydrolase fold

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0191|M.gilvum_PYR-GCK          ---------------MTDP---------QTLTLTLPHLTVTALSWGPPD-
Mvan_0714|M.vanbaalenii_PYR-1       ------------MAQVTAP---------QTLRLSLPHLDVAALSWGPPD-
MSMEG_1998|M.smegmatis_MC2_155      ---------------MTAP---------ERLTLDLPHLRFAALAWGPKD-
Mb1155|M.bovis_AF2122/97            MRAGRGERESTWRTTMAEP---------HWIDVKGPNGDLKALTWGPAG-
Rv1124|M.tuberculosis_H37Rv         MRAGRGERESTWRTTMAEP---------HWIDVKGPNGDLKALTWGPAG-
MMAR_4334|M.marinum_M               ---------------MPEP---------RWIDVPGPNGDLKALTWGRPE-
MUL_0144|M.ulcerans_Agy99           --------MTTTRPVMPEP---------RWIDVPGPNGDLKALTWGRPE-
MAV_1256|M.avium_104                -------------MKMAEP---------GWIDVTGPAGDLKALTWGPPD-
TH_2114|M.thermoresistible__bu      -------------VTMTEP---------RWIDVRTPGADLRALVWEPAES
MAB_4573c|M.abscessus_ATCC_199      ---------------MAAD---------CYLTLDLPNVRLRALAWGPQD-
MLBr_02297|M.leprae_Br4923          -------------MAMSNPSVTRIAGPWHHLDVHANGIRFHVVEAVPTQP
                                                   :.             : :      . .:       

Mflv_0191|M.gilvum_PYR-GCK          -----------GRLVLCLHGFPDSAWGWRKFAPILAEHGFRVVAPFSRGY
Mvan_0714|M.vanbaalenii_PYR-1       -----------GRLVLCLHGFPDSAWGWRKFAPLLAERGMRVVAPFSRGY
MSMEG_1998|M.smegmatis_MC2_155      -----------GRLMLCLHGYPDSAWTWRHLGPHFAAQGFRVVAPFMRGY
Mb1155|M.bovis_AF2122/97            -----------APVALCLHGFPDTAYGWRKVAPRLAESGWHVVAPFMRGY
Rv1124|M.tuberculosis_H37Rv         -----------APVALCLHGFPDTAYGWRKVAPRLAESGWHVVAPFMRGY
MMAR_4334|M.marinum_M               -----------APMALCLHGFPDTAYGWRKLAPILVDSGWRVVAPFMRGY
MUL_0144|M.ulcerans_Agy99           -----------APMALCLHGFPDTADGWRKLAPILVDSGWRVVAPFMRGY
MAV_1256|M.avium_104                -----------GPLALCLHGFPDTPYGWRKLAPRLADAGWRVVAPFMRGY
TH_2114|M.thermoresistible__bu      D---------NAPIALCLHGFPDTAHGWRKLAPLLADAGWRVVAPFNRGY
MAB_4573c|M.abscessus_ATCC_199      -----------GPLVICGHGFPDSAHTWRLLGPRLGAEGWRVVAPFTRGY
MLBr_02297|M.leprae_Br4923          AGQDCAPSATARPLVMLLHGFGSFWWSWRHQLRGLTEA--RLVAVDLRGY
                                                 : :  **: .    **     :     ::**   ***

Mflv_0191|M.gilvum_PYR-GCK          APTGPAPDGDYHIGALMYDALAVHRELGAPDDAVLIGHDWGGFTAAGIAA
Mvan_0714|M.vanbaalenii_PYR-1       APTGPAPDGDYHIGALMYDALAVHRELGAPDDAVLIGHDWGAFTASAIAA
MSMEG_1998|M.smegmatis_MC2_155      APTELARDGDYGLGALMYDAVTLHEALGGTGDAVLVGHDWGGLASAGVAA
Mb1155|M.bovis_AF2122/97            APSSIPADGSYHVGALMHDALRVRSAAGGTERDVIIGHDWGAIAATGLAA
Rv1124|M.tuberculosis_H37Rv         APSSIPADGSYHVGALMHDALRVRSAAGGTERDVIIGHDWGAIAATGLAA
MMAR_4334|M.marinum_M               APSAIPADGSYHVGALMDDALRVRSAAGATEGDVLIGHDWGAIAAAGLAA
MUL_0144|M.ulcerans_Agy99           APSAIPADGSYHVGALMDDALRVRSAAGATEGDVLIGHDWGAIAAAGLAA
MAV_1256|M.avium_104                APSAIPSDGSYHVGALMDDALRVRAAAGGTENDVVIGHDWGAIAATGLAA
TH_2114|M.thermoresistible__bu      APSSPAHDGSYHVGALMDDALRVLDAAGRTGRDLLIGHDWGAIAGAGLAA
MAB_4573c|M.abscessus_ATCC_199      APSEIPADAEYGLGALMQDVLDIHTVLGGDERAIYIGHDWGALVGNALAR
MLBr_02297|M.leprae_Br4923          GGSDKPPRG-YDGWTLAGDTAGLIRALG-HSSATLVGHAEGGLACWATAL
                                    . :  .  . *   :*  *.  :    *       :**  *.:.  . * 

Mflv_0191|M.gilvum_PYR-GCK          YPDSPFAEHITMAVAP---IGAVNRTRGPLT--RQLALLPKQLRNSWYIM
Mvan_0714|M.vanbaalenii_PYR-1       YPGSPFADHVSMAVPP---VGAINRTRGSLA--RQLRMMPRQLRNSWYIL
MSMEG_1998|M.smegmatis_MC2_155      YPKNPFGTVVSMGVPV---VAGM-RDAGNRR--RLAPLLPVQMRMSWYIL
Mb1155|M.bovis_AF2122/97            MPDSPFAKAVIMSVPPSAAFRPLG-RVPERG--RLLRELPHQLLRSWYIL
Rv1124|M.tuberculosis_H37Rv         MPDSPFAKAVIMSVPPSAAFRPLG-RVPERG--RLLRELPHQLLRSWYIL
MMAR_4334|M.marinum_M               MPDSPFSRAVIMSVPPAAAFRPLG-RVPDRG--RLARELPHQLLRSWYIL
MUL_0144|M.ulcerans_Agy99           MPDSPFSRAVIMSVPPAAAFRPLG-RVPDRG--RLARELPHQLLRSWYIL
MAV_1256|M.avium_104                MPDSPFAKAVLMSVPPSAAFRRRGGSAAERG--RLAAHLARQVFRSWYIM
TH_2114|M.thermoresistible__bu      MPDSPFTRAVIMSVPPAASFRPLG-RVADPA--RLAARLPRQLLRSWYIM
MAB_4573c|M.abscessus_ATCC_199      SGRSPFARIVTMAVPP---FEVLGSNMASIGPGGWPAVLARQLFMSWYTL
MLBr_02297|M.leprae_Br4923          LHPRLVRAIALINSPHPAALRRSMLTHRNQG----YALLPTLLR---YQL
                                         .     :  .    .                  :.  :    * :

Mflv_0191|M.gilvum_PYR-GCK          FFQLPELPERLLPRVIPRLWRDWGPQGYDTGAELA----DALAALPSPAH
Mvan_0714|M.vanbaalenii_PYR-1       FFQLPGLPERLLPRVIPRLWQDWGPAGYDTAAELD----DALAALPSPAH
MSMEG_1998|M.smegmatis_MC2_155      FQQIPWLSERNLGRVIPKLWRDWCPPGYDAREDLA----HLWEALPDTRR
Mb1155|M.bovis_AF2122/97            YFQLPWLPERSASWVVPLLWRRWSP-GYHAEEDLR----HVDAAIGTPEG
Rv1124|M.tuberculosis_H37Rv         YFQLPWLPERSASWVVPLLWRRWSP-GYHAEEDLR----HVDAAIGTPEG
MMAR_4334|M.marinum_M               YFQLPWLPERSASWVPRLLWRRWSP-TYYAEEDLR----HVDAAIGTAEG
MUL_0144|M.ulcerans_Agy99           YFQLPWLPERWASWVPRLLWRRWSP-TYYAEEDLR----HVDAAIGTAEG
MAV_1256|M.avium_104                YFQLPWLPERSASWVLPLLWRRWSP-GYRAEEDLR----HVDAAIGAPES
TH_2114|M.thermoresistible__bu      YFQLPWLPDRSSKWVVPALWRHWSP-DYPADEDIE----LVRDAIGAPER
MAB_4573c|M.abscessus_ATCC_199      FHQLPLLPEWLLPWLLRLYWRRWSP-GYDARADLL----YTGEAMLQKGN
MLBr_02297|M.leprae_Br4923          PIWPERLLTRNNAAEIERLVRSRSSAKWQACEDFAVTIDHLRIAIQIPAA
                                          *             :   .  : :  ::         *:     

Mflv_0191|M.gilvum_PYR-GCK          RRAAVAYYRAMVRPSEPSGR-YADLHRWCFDV-PRVPILHLQGELDGAME
Mvan_0714|M.vanbaalenii_PYR-1       RRAAVSYYRAMVRPSRPGRM-YADLHKWCFEL-PRAPILHVQGKQDGAMQ
MSMEG_1998|M.smegmatis_MC2_155      RTAALAYYRAALRPWRRGS--HAELDRYAMTQNPISPMLVLHGRLDGAID
Mb1155|M.bovis_AF2122/97            RRAALGPYRATMRNTRAPAD-YADLNRLWTEA-PKLPVLYLHGHDDGCAT
Rv1124|M.tuberculosis_H37Rv         RRAALGPYRATMRNTRAPAD-YADLNRLWTEA-PKLPVLYLHGHDDGCAT
MMAR_4334|M.marinum_M               WRAALGPYRATIRNTRPPAR-YAELNRWWTEA-PQLPVLYLHGRDDGCAA
MUL_0144|M.ulcerans_Agy99           WRAALGPYRATIRNTRPPAR-YAELNRWWTEA-PQLPVLYLHGRDDGCAA
MAV_1256|M.avium_104                WRAALGPYRATIRNTAPPAQ-YATLHRLWTEE-PVLPCLYLHGRDDGCMT
TH_2114|M.thermoresistible__bu      WRAALGYYRATIRNTRPPHR-YAELHQHWLSA-PRIPTLYLHGADDGCAT
MAB_4573c|M.abscessus_ATCC_199      RRAVIGYYRANIRGALFPARKYWPTQRSLLDG-ARTPMLYLHGRNDGCMT
MLBr_02297|M.leprae_Br4923          AHCALEYQRWAVRSQLRNEG--RKFMKSMSRP-FSVPLLHVRGDADPYLL
                                      ..:   *  :*             :         * * ::*  *    

Mflv_0191|M.gilvum_PYR-GCK          AEYAAPIATALPAGSRVRIIDEAGHFLQIERPQVTADTVLDYLGDRRGPR
Mvan_0714|M.vanbaalenii_PYR-1       AGYAEPIGAVLPPGSRVVTIPAAGHFLQIERPAETAAAVLQYLGDRSGPR
MSMEG_1998|M.smegmatis_MC2_155      VRIGTLSASVLVPGSRHEVIDGAGHFMHLDRPDEVHALIADYANL-----
Mb1155|M.bovis_AF2122/97            SAFTHWTARVLPAGSEVAVVEHAGHFLQLEQPDKIAELIVAFIGSPG---
Rv1124|M.tuberculosis_H37Rv         SAFTHWTARVLPAGSEVAVVEHAGHFLQLEQPDKIAELIVAFIGSPG---
MMAR_4334|M.marinum_M               VAFTHWTERVLPPGSEVAVVEQAGHFLQLEQPETVAKLILPFIAPPG---
MUL_0144|M.ulcerans_Agy99           VAFTHWTERVLPPGSEVAVVEQAGHFLQLEQPEAVAKLILPFIAPPG---
MAV_1256|M.avium_104                SAFAHQVEKVLPPGSEVDIVEHAGHFLQLEQPDKVAGLVLGFIGSPG---
TH_2114|M.thermoresistible__bu      PDYARWVEPVLPVGSAVAILDRAGHFLQLDRPDAVADHILRFAG------
MAB_4573c|M.abscessus_ATCC_199      YRLIDSARPDLPDRS-VEIINGGGHFVHLECPDVVYELVREFLGPPTSKV
MLBr_02297|M.leprae_Br4923          ADSVDRTRRYAPHGRYVSVSD-AGHFSHEEAPEEINRYLTRFLKQVHGPR
                                                          .*** : : *      :  :        

Mflv_0191|M.gilvum_PYR-GCK          --
Mvan_0714|M.vanbaalenii_PYR-1       --
MSMEG_1998|M.smegmatis_MC2_155      --
Mb1155|M.bovis_AF2122/97            --
Rv1124|M.tuberculosis_H37Rv         --
MMAR_4334|M.marinum_M               --
MUL_0144|M.ulcerans_Agy99           --
MAV_1256|M.avium_104                --
TH_2114|M.thermoresistible__bu      --
MAB_4573c|M.abscessus_ATCC_199      E-
MLBr_02297|M.leprae_Br4923          LS