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M. thermoresistible (build 8) TH_2100 ()

annotation: PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
coordinates: 4120759 - 4122165
length: 469

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2100-100% (469)PROBABLE CONSERVED TRANSMEMBRANE PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0148c-0.068.57% (455) transmembrane protein
M. gilvum PYR-GCKMflv_2009-3e-2329.62% (449) Cl- channel, voltage-gated family protein
M. tuberculosis H37RvRv0143c-0.068.57% (455) transmembrane protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0355-0.000126.02% (269) ammonium transporter
M. marinum MMMAR_0353-0.068.70% (460) hypothetical protein MMAR_0353
M. avium 104MAV_4918-2e-1625.07% (375) chloride transporter, chloride channel (ClC) family protein
M. smegmatis MC2 155MSMEG_6465-0.075.56% (450) chloride channel
M. ulcerans Agy99MUL_1164-3e-1626.51% (347) transmembrane protein
M. vanbaalenii PYR-1Mvan_4719-5e-2329.76% (420) Cl- channel, voltage-gated family protein

CLUSTAL 2.0.9 multiple sequence alignment


TH_2100|M.thermoresistible__bu      ------------------------MREVAGGGRIGGYVNRLGYLPRWLLL
MSMEG_6465|M.smegmatis_MC2_155      ----------------------MRTRPRIDGG-LGNFVRNSGYVRKWLIL
Mb0148c|M.bovis_AF2122/97           MAPGDWSVFAWHAANLPTMPEAEDIGNEAAGGRLGVSIRSAGYLRKWFLL
Rv0143c|M.tuberculosis_H37Rv        MAPGDWSVFAWHAANLPTMPEAEDIGNEAAGGRFGVSIRSAGYLRKWFLL
MMAR_0353|M.marinum_M               MSP------------------------AAAGGRFGASIRNAGYLQKWFLL
Mflv_2009|M.gilvum_PYR-GCK          -----------------------------MPLRLRPGGP-VRSLLVVVGT
Mvan_4719|M.vanbaalenii_PYR-1       -----------------------------MDPGVGDARPSLHRSAVLSAA
MAV_4918|M.avium_104                ------------------------MPAP----------RSDRNALDFFCA
MUL_1164|M.ulcerans_Agy99           ------------------------MPASFSGRFASVLRRASRRDVDFFCA
MAB_0355|M.abscessus_ATCC_1997      ---------------------------------------------MFPHM
                                                                                      

TH_2100|M.thermoresistible__bu      GVVIGVIAGLGAVVFYLALDYSTRLLLGHLGGYDIPEAVGDGGDPGSAGF
MSMEG_6465|M.smegmatis_MC2_155      GIAIGVIAGLGAVVFYLALDGAGRVLLGYLGGYDIPKPSGDGGNPGSPGF
Mb0148c|M.bovis_AF2122/97           GITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGF
Rv0143c|M.tuberculosis_H37Rv        GITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGF
MMAR_0353|M.marinum_M               GITIGGIAGLGAVVFYLALKYTGEFLLGYLADYHIPTPVGEGGSHGSSGF
Mflv_2009|M.gilvum_PYR-GCK          AALAGAVIGIVGAAFQWCLRAAEGLRLDVVEWAQRLPGPG----------
Mvan_4719|M.vanbaalenii_PYR-1       AIVAGVVIGLVGGAFRWCLQAAESLRVDVVEWAQRLPGPG----------
MAV_4918|M.avium_104                VIIVGVLAGIAGVATTLVLRVVQHATYHYSFGALLAGVAA----------
MUL_1164|M.ulcerans_Agy99           VVIVGLLAGVAGLSTTVVLRFVEHLTYHYAFGSLLEGITG----------
MAB_0355|M.abscessus_ATCC_1997      GVPDAANTAWVLTSAALVLLMTPALAFFYGGMVRAKSVLN----------
                                        .   .         *                               

TH_2100|M.thermoresistible__bu      QRPWAIPLIACTGALVSAWLIARFAPEAEGHGTDDAIEAVHTDPRRIRGR
MSMEG_6465|M.smegmatis_MC2_155      DRPWAIPLISCGGALVSAWFVAKFAPEAEGHGTDDAIEAVHTDPRKIRVR
Mb0148c|M.bovis_AF2122/97           ARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGR
Rv0143c|M.tuberculosis_H37Rv        ARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGR
MMAR_0353|M.marinum_M               VRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSR
Mflv_2009|M.gilvum_PYR-GCK          ---WLIPVALVAFCAAVARTLVRWEPQAAGSGIPHVEAVFLGETSPPRLR
Mvan_4719|M.vanbaalenii_PYR-1       ---WLVPMGVVAACATAAALLVRWEPLAVGSGIPHVEAVFLGEAAPPPLR
MAV_4918|M.avium_104                ----SSPIRRVLGPMVGAALAGLGWWLLRRRTDVPPLAETIARSERVPRL
MUL_1164|M.ulcerans_Agy99           ----SSPVRRALGPMVGGALAGLGWWLLRRRTDVPPLAGTIADHARIPRR
MAB_0355|M.abscessus_ATCC_1997      ------MMMMCFSAVAVVWLLWVIFGYSMAFGTDIGGGLLGDPFQFAGLQ
                                           :                                          

TH_2100|M.thermoresistible__bu      AIVVKTVASALTIGSGGSGGREGPAAQISAGFGSLLTRRLD-LSDDDGRI
MSMEG_6465|M.smegmatis_MC2_155      AIVVKTIASALTIGSGGSGGREGPAAHISAGFGSLLTRWLN-LSDEDGRL
Mb0148c|M.bovis_AF2122/97           AVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLN-LSNEDGRT
Rv0143c|M.tuberculosis_H37Rv        AVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLN-LSNEDGRT
MMAR_0353|M.marinum_M               AVLVKMVASALTIGSGGSGGREGPTAQISAGFCSFLTRRLG-LSDEDGRT
Mflv_2009|M.gilvum_PYR-GCK          VLPARFVGGVLGIGSGLVLGREGPTVHMGAAIGAQAARRSC-LSDGDVRL
Mvan_4719|M.vanbaalenii_PYR-1       LVFARFVGGVLAIGGGLVLGREGPTVHIGAAVGAEAARRTR-LPSSEAAT
MAV_4918|M.avium_104                AWSIDAVLQVLLVGSGASLGREGAPRQFASALGDFGIGWLRRLSSRDREI
MUL_1164|M.ulcerans_Agy99           TWSIDALLQVVLVGSGASLGREGAPRQFAAALSDFATTWLRRLSPGDREI
MAB_0355|M.abscessus_ATCC_1997      HLFEGDYKAPSVPLWGPTNIPALVFVMFQAGFAMVTVALIAGAVADRMRF
                                                   *           : :..                  

TH_2100|M.thermoresistible__bu      AVSLGIGAGIGAIFGAPLGGAVLAAS-IGYRKDFDYTVLVPGFIASAAAY
MSMEG_6465|M.smegmatis_MC2_155      AVSLGIGAGIGAIFGAPLGGAVLAAS-IVYRDDFDYRALIPGFITSASAY
Mb0148c|M.bovis_AF2122/97           AVALGIGAGIGAIFAAPLGGAALGAS-IPYRDDFDYRNLLPGFIASGTAY
Rv0143c|M.tuberculosis_H37Rv        AVALGIGAGIGAIFAAPLGGAALGAS-IPYRDDFDYRNLLPGFIASGTAY
MMAR_0353|M.marinum_M               AVALGIGAGIGAIFAAPLGGAVLAAS-ITYRDDFDYRSLLPGFITSGTAY
Mflv_2009|M.gilvum_PYR-GCK          VQTALAGAGLAVAFNAPIAGVLFTLE-EVTRS-LRARTVLATVAATVTAV
Mvan_4719|M.vanbaalenii_PYR-1       MQAALGGAGLAVAFNAPLAGVLFTLE-EVTKS-WRLQAVLVSVFAAAAAV
MAV_4918|M.avium_104                LLACAAGAGLGAVYAVPLAGALFAAR-ILLRT-WRLRAVGAAFLSSGVAV
MUL_1164|M.ulcerans_Agy99           LLACAAGAGLGAVYAVPLAGALFALR-IMLNT-WNIRALGAALITSSLAV
MAB_0355|M.abscessus_ATCC_1997      LPWIAFTALWATLVYFPVAHWIFAVEGTTADKGGWLANLGVLDFAGGTAV
                                           *  ..    *:.   :               :     :   * 

TH_2100|M.thermoresistible__bu      AVFGSILGFDPLFGHVAADFRFDHAALLLWFVVLGVLSAGVGYLYARTFY
MSMEG_6465|M.smegmatis_MC2_155      AVLGSILGFDPLFGFLVGDYRFGQALDLAWFVVLGVIAGGVGWLYARVFY
Mb0148c|M.bovis_AF2122/97           AVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFH
Rv0143c|M.tuberculosis_H37Rv        AVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFH
MMAR_0353|M.marinum_M               AVLGAFMGFDPLFGYIDAEYRFEKAWPLLWFVVIGVVAAAIGYLYARVFH
Mflv_2009|M.gilvum_PYR-GCK          LASRLILADQPDFD--VHAVVAPGLAWLPLFVVFGVLTGLLGAAYNVVVV
Mvan_4719|M.vanbaalenii_PYR-1       GTSRLLLGDHPDFG--VPTVPAPELVWLPLFLVFGVLTGFLGAGYNLVVL
MAV_4918|M.avium_104                AVGSAVTGDQPNLRWPVEES---TYLLTAHGLLLAPVALAVGLVFNRLMA
MUL_1164|M.ulcerans_Agy99           AIGSLVTHDRPELDWPSAES---TYLLSAHALALAPVAFVVGVAFNRIMA
MAB_0355|M.abscessus_ATCC_1997      EINSGAAGLALAIVLGKRRGWPREAMRPHNLPAVMLGAGLLWFGWFGFNA
                                                :                    .   :  :   :     

TH_2100|M.thermoresistible__bu      GIRAVTADLPGGR-IVKPALGGLAVGLLGLALPQVLSSGYGWAQKATVTD
MSMEG_6465|M.smegmatis_MC2_155      GTVAVTKMLPGGK-IVKPALGGLAVGLMALAIPQVLASGYGWAEKAAATE
Mb0148c|M.bovis_AF2122/97           ASVAITRRLPGGP-VLKPAIGGLLVGLLGLPIPQILSSGYGWAQLAADRG
Rv0143c|M.tuberculosis_H37Rv        ASVAITRRLPGGP-VLKPAIGGLLVGLLGLPIPQILSSGYGWAQLAADRG
MMAR_0353|M.marinum_M               ASVGLAHRLPGGP-VIKPAVGGLLVGLMGLLIPQILSSGYGWAQLAADRN
Mflv_2009|M.gilvum_PYR-GCK          WSTDRVAAIPRVPTELKAAAIGAAVGALLWVAPLTVGDGDTLTQMILDG-
Mvan_4719|M.vanbaalenii_PYR-1       WALDHVAAIRRIPTLVQAGAIGAAVGLLLCVAPLTVGDGDTLTQMLLGG-
MAV_4918|M.avium_104                VAR-PARPMRTWTLIPALAGAGLVTGVCSHWWPELPGNGRSILTVSLAS-
MUL_1164|M.ulcerans_Agy99           AAR-PASLVRSWTLIPGLAAAGLAIGICSHWWPELPGNGKSILTVSLPS-
MAB_0355|M.abscessus_ATCC_1997      GSALAADGTAALVIANTLGAGAISMASWLLVEKVRHGKPTSFGAASGVVA
                                         .            .  .   .          ..            

TH_2100|M.thermoresistible__bu      TLMALPLWLVLVVPFAKILATGLSIGTGGSGGIFGPGVVIGAFVGAA-LW
MSMEG_6465|M.smegmatis_MC2_155      TLMNIPLWIVLVLPVAKIVATSLSIGTGGSGGIFGPGVVIGAFVGAA-LW
Mb0148c|M.bovis_AF2122/97           TLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAA-IW
Rv0143c|M.tuberculosis_H37Rv        TLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAA-IW
MMAR_0353|M.marinum_M               ALMAIPLWIIIVLPVAKILATSLSIGTGGSGGLFGPGIVIGAFVGAA-IW
Mflv_2009|M.gilvum_PYR-GCK          --HGFVLLAAVGLLAARFFTGPMSYAAAVPGGLFAPLLAVGALWGYV-FV
Mvan_4719|M.vanbaalenii_PYR-1       --HQFVLLATAGLLAARFLTGPLCYSAAVPGGLFAPLLAIGALWGTL-FV
MAV_4918|M.avium_104                ---GMTLASALAILLLKPVLTALFLRAGGAGGLLTPSLATGAAAGTA-LV
MUL_1164|M.ulcerans_Agy99           ---GMTLSAAAVILVLKPLLTALVLRVGGAGGMLTPSLATGAAAGSL-LV
MAB_0355|M.abscessus_ATCC_1997      GLVAITPSCAAVTPIGALIIGAVTGAVSSLAIELKYRLGYDDSLDVVGVH
                                        :             .   :   ..  .  :   :  .   .   . 

TH_2100|M.thermoresistible__bu      RLGEAVDAPGLPESPGVFVVVGMMACFGSVAHVPLAVLLMVAEMTGSFSV
MSMEG_6465|M.smegmatis_MC2_155      RLGDALALPGIPDSPAIFVVVGMMACFGCVAHAPLAVMIMVCEMTSSFAV
Mb0148c|M.bovis_AF2122/97           RLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSV
Rv0143c|M.tuberculosis_H37Rv        RLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSV
MMAR_0353|M.marinum_M               RLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSV
Mflv_2009|M.gilvum_PYR-GCK          TCLGAIAPESASALVIPMALVGMAAFFGATVRAPLTGVVIVLEMTATTTV
Mvan_4719|M.vanbaalenii_PYR-1       GCFGAVWPDDPTFLAIPMALAGMAAFFGATVRAPLTGLLIVIEMTATTSV
MAV_4918|M.avium_104                LT--INWATGSQLHVPAVSLAGAAGVLAVTQGSPIWAAIFVWELARPPLW
MUL_1164|M.ulcerans_Agy99           LA--ILAVAGTHLHGPVISLAAAAGVLAVTQGSPIWAAIFVWELARPPIW
MAB_0355|M.abscessus_ATCC_1997      LVGGVVGTLMIGVVGSAAAPAGVNGLLYGGGLHQFWLQLVGVVTVLVYSV
                                                        ..    :       :   :.    .     

TH_2100|M.thermoresistible__bu      VPGAMVAVGLAYLLITRT-DVSIYAAQRMDRESAAAERARRGAGGDS---
MSMEG_6465|M.smegmatis_MC2_155      IPCAMVGVGVACLTISRS-DVAIYRAQRARREPEPA--------------
Mb0148c|M.bovis_AF2122/97           VPGAIIAVGIAALLLSRT-NVTIYETQRLNRQTAEAERGGSDRPTTA---
Rv0143c|M.tuberculosis_H37Rv        VPGAIIAVGIAALLLSRT-NVTIYETQRLNRQTAEAERGGSDRPTTA---
MMAR_0353|M.marinum_M               VPGAILAVGIASLLMSRT-NVTIYEAQRLNRETAEAERAARAADRGN---
Mflv_2009|M.gilvum_PYR-GCK          ALPMLAACVSAVLAARAVGSAPIYASLRDRMLVEPVAAPGVDEGR-----
Mvan_4719|M.vanbaalenii_PYR-1       AVPMMIATAAAVVSANALGSAPIYDSLRERMPVS----SGPDRS------
MAV_4918|M.avium_104                LFLLFLLTATAAHGLKVLAQGR----TTTHAG------------------
MUL_1164|M.ulcerans_Agy99           MLVVFLVTAVGAHGLKTLVLGRRLPLRDHRAG------------------
MAB_0355|M.abscessus_ATCC_1997      AVTGLIGLGLRHSLGIRSHPQHESDGLDDAEHAESAYELATTRGGGLINP
                                        :                                             

TH_2100|M.thermoresistible__bu      --
MSMEG_6465|M.smegmatis_MC2_155      --
Mb0148c|M.bovis_AF2122/97           --
Rv0143c|M.tuberculosis_H37Rv        --
MMAR_0353|M.marinum_M               --
Mflv_2009|M.gilvum_PYR-GCK          --
Mvan_4719|M.vanbaalenii_PYR-1       --
MAV_4918|M.avium_104                --
MUL_1164|M.ulcerans_Agy99           --
MAB_0355|M.abscessus_ATCC_1997      GR