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M. thermoresistible (build 8) TH_2044 (-)

annotation: PROBABLE 3-ISOPROPYLMALATE DEHYDRATASE (SMALL SUBUNIT) LEUD (ISOPROPYLMALATE ISOMERASE) (ALPHA-IPM ISOMERASE) (IPMI)
coordinates: 4011847 - 4012440
length: 198

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_2044 - - 100% (198) PROBABLE 3-ISOPROPYLMALATE DEHYDRATASE (SMALL SUBUNIT) LEUD (ISOPROPYLMALATE ISOMERASE) (ALPHA-IPM ISOMERASE) (IPMI)

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3011c leuD 4e-96 83.76% (197) isopropylmalate isomerase small subunit
M. gilvum PYR-GCK Mflv_4226 leuD 1e-101 88.32% (197) isopropylmalate isomerase small subunit
M. tuberculosis H37Rv Rv2987c leuD 4e-96 83.76% (197) isopropylmalate isomerase small subunit
M. leprae Br4923 MLBr_01684 leuD 1e-96 83.67% (196) isopropylmalate isomerase small subunit
M. abscessus ATCC 19977 MAB_3293c leuD 2e-93 81.54% (195) isopropylmalate isomerase small subunit
M. marinum M MMAR_1727 leuD 2e-98 86.73% (196) 3-isopropylmalate dehydratase (small subunit) LeuD
M. avium 104 MAV_3837 leuD 3e-98 86.22% (196) isopropylmalate isomerase small subunit
M. smegmatis MC2 155 MSMEG_2388 leuD 1e-104 91.37% (197) isopropylmalate isomerase small subunit
M. ulcerans Agy99 MUL_1969 leuD 2e-98 86.73% (196) isopropylmalate isomerase small subunit
M. vanbaalenii PYR-1 Mvan_2136 leuD 1e-100 87.82% (197) isopropylmalate isomerase small subunit

CLUSTAL 2.0.9 multiple sequence alignment


Mb3011c|M.bovis_AF2122/97           MEAFHTHSGIGVPLRRSNVDTDQIIPAVFLKRVTRTGFEDGLFAGWRSDP
Rv2987c|M.tuberculosis_H37Rv        MEAFHTHSGIGVPLRRSNVDTDQIIPAVFLKRVTRTGFEDGLFAGWRSDP
MLBr_01684|M.leprae_Br4923          MQAFRVHTGIGVPLRRSNVDTDQIIPAVFLKRVTRNGFEDGLFATWRVDP
MMAR_1727|M.marinum_M               MEAFDTHTGIGVPLRRSNVDTDQIIPAVFLKRVTRTGFEDGLFASWRSDP
MUL_1969|M.ulcerans_Agy99           MEAFDTHTGIGVPLRRSNVDTDQIIPAVFLKRVTRTGFEDGLFASWRSDP
MAV_3837|M.avium_104                MEAFHTHTGIGVPLRRSNVDTDQIIPAVYLKRVTRTGFEDGLFASWRSDP
Mflv_4226|M.gilvum_PYR-GCK          MEAFRTHTGIGVPLRRSNVDTDQIIPAVYLKRVTRTGFEDGLFAAWRNDP
Mvan_2136|M.vanbaalenii_PYR-1       MEAFRTHTGIGVPLRRSNVDTDQIIPAVYLKRVTRTGFEDGLFAAWRNDP
TH_2044|M.thermoresistible__bu      MQPFRTHTGIGVPLRRSNVDTDQIIPAVYLKRVTRTGFEDGLFAAWRTDP
MSMEG_2388|M.smegmatis_MC2_155      MEAFTTHTGIGVPLRRSNVDTDQIIPAVYLKRVTRTGFEDGLFAAWRNDP
MAB_3293c|M.abscessus_ATCC_199      MEAFDTHTGIGVPLRRSNVDTDQIIPAVYLKRVTRTGFEDGLFAGWRTDP
                                    *:.* .*:********************:******.******** ** **

Mb3011c|M.bovis_AF2122/97           AFVLNLSPFDRGSVLVAGPDFGTGSSREHAVWALMDYGFRVVISSRFGDI
Rv2987c|M.tuberculosis_H37Rv        AFVLNLSPFDRGSVLVAGPDFGTGSSREHAVWALMDYGFRVVISSRFGDI
MLBr_01684|M.leprae_Br4923          SFVLNLSPFDRGSVLVVGPDFGIGSSREHAVWALMDYGFRVVISSRFGDI
MMAR_1727|M.marinum_M               SFVLNLSPFDRGSVLVAGPDFGTGSSREHAVWALMDYGFRVVISSRFGDI
MUL_1969|M.ulcerans_Agy99           SFVLNLSPFDRGSVLVAGPDFGTGSSREHAVWALMDYGFRVVISSRFGDI
MAV_3837|M.avium_104                SFVLNLSPFDRGSVLVAGPDFGTGSSREHAVWALMDYGFRVVISSRFGDI
Mflv_4226|M.gilvum_PYR-GCK          SFVLNQPPFDQGSVLVTGPDFGTGSSREHAVWALMDFGFRVVISSRFADI
Mvan_2136|M.vanbaalenii_PYR-1       SFVLNLAPFDKGSVLVAGPDFGTGSSREHAVWALMDFGFRVVISSRFADI
TH_2044|M.thermoresistible__bu      SFVLNVPPYDKGSVLVAGPDFGTGSSREHAVWALMDYGFRVVISSRFADI
MSMEG_2388|M.smegmatis_MC2_155      SFILNLSPFDKGSVLVAGPDFGTGSSREHAVWALMDYGFRVVISSRFADI
MAB_3293c|M.abscessus_ATCC_199      SFILNLEPFNRGTVLVAGPEFGTGSSREHAVWALMDYGFRVVLSSRFGDI
                                    :*:**  *:::*:***.**:** *************:*****:****.**

Mb3011c|M.bovis_AF2122/97           FRGNAGKAGLLAAEVAQDDVELLWKLIEQSPGLEITANLQDRIITAATVV
Rv2987c|M.tuberculosis_H37Rv        FRGNAGKAGLLAAEVAQDDVELLWKLIEQSPGLEITANLQDRIITAATVV
MLBr_01684|M.leprae_Br4923          FHGNAGKAGLLAAQVAQDDVEFLWKLIEQKPGLEITVNLQDRNINAATVV
MMAR_1727|M.marinum_M               FRGNAGKAGLLAAEVDQDGVELLWKLIEQSPGLEITVNLQDRNVIAGTVV
MUL_1969|M.ulcerans_Agy99           FRGNAGKAGLLAAEVDQDGVELLWKLIEQSPGLEITVNLQDRNVIAGTVV
MAV_3837|M.avium_104                FRGNAGKAGLLAAEVSQDGVELLWKLIEQSPGLEITANLQDRNITAGTTV
Mflv_4226|M.gilvum_PYR-GCK          FRGNAGKAGLLAAEVTQDDVELLWKVIEQHPGTEITVNLQDRSVTAGTVM
Mvan_2136|M.vanbaalenii_PYR-1       FRGNAGKAGLLAAEVSQDDVELLWKLIEQHPGTEITVNLQDRTITAGTMM
TH_2044|M.thermoresistible__bu      FRGNAGKAGLLAAEVSQDDVELLWKALEQNPGLEITVNLQDRTVTAGTVV
MSMEG_2388|M.smegmatis_MC2_155      FRGNAGKAGLLAAEVAQDDVELLWKVIEQNPGLEITVNLQDRTVTAGTVV
MAB_3293c|M.abscessus_ATCC_199      FRGNAGKAGLVAGLVGQSDIELLWKLIEQNPGLELTVNLEDRTVTAGTAV
                                    *:********:*. * *..:*:*** :** ** *:*.**:** : *.* :

Mb3011c|M.bovis_AF2122/97           LPFKIDDHSAWRLLEGLDDIALTLRKLDEIEAFEGACAYWKPRTLPAP-
Rv2987c|M.tuberculosis_H37Rv        LPFKIDDHSAWRLLEGLDDIALTLRKLDEIEAFEGACAYWKPRTLPAP-
MLBr_01684|M.leprae_Br4923          LPFKIDDYTAWRLLEGLDDIALNLRKLDEIEAFESARPAWKPRTLPTT-
MMAR_1727|M.marinum_M               LPFRIDDHTAWRLLEGLDDIALTLRKLDEIEAYEAAYPAWKPRTLPTS-
MUL_1969|M.ulcerans_Agy99           LPFRIDDHTAWRLLEGLDDIALTLRKLDEIEAYEAAYPAWKPRTLPTS-
MAV_3837|M.avium_104                LPFKIDDHTAWRLLEGLDDIALTLRKLDRIESYEAAYPDWKPRTSPVA-
Mflv_4226|M.gilvum_PYR-GCK          VPFTIDDYTAWRLLEGLDDIGLTLRKLDEIEDFETHRPSWKPRTLPA--
Mvan_2136|M.vanbaalenii_PYR-1       VLFNIDDYTAWRLLEGLDDIGLTLRKLDEIEDYERHRPEWKPHTLPA--
TH_2044|M.thermoresistible__bu      VPFKIDDYTAWRLLEGLDDIALTLRKQDQIEAYEARRPSWKPRTLPA--
MSMEG_2388|M.smegmatis_MC2_155      VPFRIDDYTRWRLLEGLDDIGLTLRKLDQIEAYEAARPAWKPRTLPA--
MAB_3293c|M.abscessus_ATCC_199      VPFEIDDYTRWRLLEGLDDIGLTLRKVDEIAAFEAARPEFKPRTLEPSE
                                    : * ***:: **********.*.*** *.*  :*   . :**:*

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_2044	-	-	100% (198)	PROBABLE 3-ISOPROPYLMALATE DEHYDRATASE (SMALL SUBUNIT) LEUD (ISOPROPYLMALATE ISOMERASE) (ALPHA-IPM ISOMERASE) (IPMI)