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EAFHTHSGIGVPLRRSNVDTDQIIPAVFLKRVTRTGFEDGLFAGWRSDPAFVLNLSPFDRGSVLVAGPDF GTGSSREHAVWALMDYGFRVVISSRFGDIFRGNAGKAGLLAAEVAQDDVELLWKLIEQSPGLEITANLQD RIITAATVVLPFKIDDHSAWRLLEGLDDIALTLRKLDEIEAFEGACAYWKPRTLPAP*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv2987c | leuD | - | 100% (198) | isopropylmalate isomerase small subunit |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3011c | leuD | 1e-113 | 100.00% (198) | isopropylmalate isomerase small subunit |
M. gilvum PYR-GCK | Mflv_4226 | leuD | 4e-94 | 83.76% (197) | isopropylmalate isomerase small subunit |
M. leprae Br4923 | MLBr_01684 | leuD | 2e-97 | 87.76% (196) | isopropylmalate isomerase small subunit |
M. abscessus ATCC 19977 | MAB_3293c | leuD | 3e-91 | 80.00% (195) | isopropylmalate isomerase small subunit |
M. marinum M | MMAR_1727 | leuD | 1e-101 | 90.82% (196) | 3-isopropylmalate dehydratase (small subunit) LeuD |
M. avium 104 | MAV_3837 | leuD | 1e-101 | 90.82% (196) | isopropylmalate isomerase small subunit |
M. smegmatis MC2 155 | MSMEG_2388 | leuD | 2e-98 | 86.29% (197) | isopropylmalate isomerase small subunit |
M. thermoresistible (build 8) | TH_2044 | - | 4e-96 | 83.76% (197) | PROBABLE 3-ISOPROPYLMALATE DEHYDRATASE (SMALL SUBUNIT) LEUD |
M. ulcerans Agy99 | MUL_1969 | leuD | 1e-101 | 90.82% (196) | isopropylmalate isomerase small subunit |
M. vanbaalenii PYR-1 | Mvan_2136 | leuD | 6e-94 | 83.76% (197) | isopropylmalate isomerase small subunit |
CLUSTAL 2.0.9 multiple sequence alignment Rv2987c|M.tuberculosis_H37Rv MEAFHTHSGIGVPLRRSNVDTDQIIPAVFLKRVTRTGFEDGLFAGWRSDP Mb3011c|M.bovis_AF2122/97 MEAFHTHSGIGVPLRRSNVDTDQIIPAVFLKRVTRTGFEDGLFAGWRSDP MLBr_01684|M.leprae_Br4923 MQAFRVHTGIGVPLRRSNVDTDQIIPAVFLKRVTRNGFEDGLFATWRVDP MMAR_1727|M.marinum_M MEAFDTHTGIGVPLRRSNVDTDQIIPAVFLKRVTRTGFEDGLFASWRSDP MUL_1969|M.ulcerans_Agy99 MEAFDTHTGIGVPLRRSNVDTDQIIPAVFLKRVTRTGFEDGLFASWRSDP MAV_3837|M.avium_104 MEAFHTHTGIGVPLRRSNVDTDQIIPAVYLKRVTRTGFEDGLFASWRSDP Mflv_4226|M.gilvum_PYR-GCK MEAFRTHTGIGVPLRRSNVDTDQIIPAVYLKRVTRTGFEDGLFAAWRNDP Mvan_2136|M.vanbaalenii_PYR-1 MEAFRTHTGIGVPLRRSNVDTDQIIPAVYLKRVTRTGFEDGLFAAWRNDP TH_2044|M.thermoresistible__bu MQPFRTHTGIGVPLRRSNVDTDQIIPAVYLKRVTRTGFEDGLFAAWRTDP MSMEG_2388|M.smegmatis_MC2_155 MEAFTTHTGIGVPLRRSNVDTDQIIPAVYLKRVTRTGFEDGLFAAWRNDP MAB_3293c|M.abscessus_ATCC_199 MEAFDTHTGIGVPLRRSNVDTDQIIPAVYLKRVTRTGFEDGLFAGWRTDP *:.* .*:********************:******.******** ** ** Rv2987c|M.tuberculosis_H37Rv AFVLNLSPFDRGSVLVAGPDFGTGSSREHAVWALMDYGFRVVISSRFGDI Mb3011c|M.bovis_AF2122/97 AFVLNLSPFDRGSVLVAGPDFGTGSSREHAVWALMDYGFRVVISSRFGDI MLBr_01684|M.leprae_Br4923 SFVLNLSPFDRGSVLVVGPDFGIGSSREHAVWALMDYGFRVVISSRFGDI MMAR_1727|M.marinum_M SFVLNLSPFDRGSVLVAGPDFGTGSSREHAVWALMDYGFRVVISSRFGDI MUL_1969|M.ulcerans_Agy99 SFVLNLSPFDRGSVLVAGPDFGTGSSREHAVWALMDYGFRVVISSRFGDI MAV_3837|M.avium_104 SFVLNLSPFDRGSVLVAGPDFGTGSSREHAVWALMDYGFRVVISSRFGDI Mflv_4226|M.gilvum_PYR-GCK SFVLNQPPFDQGSVLVTGPDFGTGSSREHAVWALMDFGFRVVISSRFADI Mvan_2136|M.vanbaalenii_PYR-1 SFVLNLAPFDKGSVLVAGPDFGTGSSREHAVWALMDFGFRVVISSRFADI TH_2044|M.thermoresistible__bu SFVLNVPPYDKGSVLVAGPDFGTGSSREHAVWALMDYGFRVVISSRFADI MSMEG_2388|M.smegmatis_MC2_155 SFILNLSPFDKGSVLVAGPDFGTGSSREHAVWALMDYGFRVVISSRFADI MAB_3293c|M.abscessus_ATCC_199 SFILNLEPFNRGTVLVAGPEFGTGSSREHAVWALMDYGFRVVLSSRFGDI :*:** *:::*:***.**:** *************:*****:****.** Rv2987c|M.tuberculosis_H37Rv FRGNAGKAGLLAAEVAQDDVELLWKLIEQSPGLEITANLQDRIITAATVV Mb3011c|M.bovis_AF2122/97 FRGNAGKAGLLAAEVAQDDVELLWKLIEQSPGLEITANLQDRIITAATVV MLBr_01684|M.leprae_Br4923 FHGNAGKAGLLAAQVAQDDVEFLWKLIEQKPGLEITVNLQDRNINAATVV MMAR_1727|M.marinum_M FRGNAGKAGLLAAEVDQDGVELLWKLIEQSPGLEITVNLQDRNVIAGTVV MUL_1969|M.ulcerans_Agy99 FRGNAGKAGLLAAEVDQDGVELLWKLIEQSPGLEITVNLQDRNVIAGTVV MAV_3837|M.avium_104 FRGNAGKAGLLAAEVSQDGVELLWKLIEQSPGLEITANLQDRNITAGTTV Mflv_4226|M.gilvum_PYR-GCK FRGNAGKAGLLAAEVTQDDVELLWKVIEQHPGTEITVNLQDRSVTAGTVM Mvan_2136|M.vanbaalenii_PYR-1 FRGNAGKAGLLAAEVSQDDVELLWKLIEQHPGTEITVNLQDRTITAGTMM TH_2044|M.thermoresistible__bu FRGNAGKAGLLAAEVSQDDVELLWKALEQNPGLEITVNLQDRTVTAGTVV MSMEG_2388|M.smegmatis_MC2_155 FRGNAGKAGLLAAEVAQDDVELLWKVIEQNPGLEITVNLQDRTVTAGTVV MAB_3293c|M.abscessus_ATCC_199 FRGNAGKAGLVAGLVGQSDIELLWKLIEQNPGLELTVNLEDRTVTAGTAV *:********:*. * *..:*:*** :** ** *:*.**:** : *.* : Rv2987c|M.tuberculosis_H37Rv LPFKIDDHSAWRLLEGLDDIALTLRKLDEIEAFEGACAYWKPRTLPAP- Mb3011c|M.bovis_AF2122/97 LPFKIDDHSAWRLLEGLDDIALTLRKLDEIEAFEGACAYWKPRTLPAP- MLBr_01684|M.leprae_Br4923 LPFKIDDYTAWRLLEGLDDIALNLRKLDEIEAFESARPAWKPRTLPTT- MMAR_1727|M.marinum_M LPFRIDDHTAWRLLEGLDDIALTLRKLDEIEAYEAAYPAWKPRTLPTS- MUL_1969|M.ulcerans_Agy99 LPFRIDDHTAWRLLEGLDDIALTLRKLDEIEAYEAAYPAWKPRTLPTS- MAV_3837|M.avium_104 LPFKIDDHTAWRLLEGLDDIALTLRKLDRIESYEAAYPDWKPRTSPVA- Mflv_4226|M.gilvum_PYR-GCK VPFTIDDYTAWRLLEGLDDIGLTLRKLDEIEDFETHRPSWKPRTLPA-- Mvan_2136|M.vanbaalenii_PYR-1 VLFNIDDYTAWRLLEGLDDIGLTLRKLDEIEDYERHRPEWKPHTLPA-- TH_2044|M.thermoresistible__bu VPFKIDDYTAWRLLEGLDDIALTLRKQDQIEAYEARRPSWKPRTLPA-- MSMEG_2388|M.smegmatis_MC2_155 VPFRIDDYTRWRLLEGLDDIGLTLRKLDQIEAYEAARPAWKPRTLPA-- MAB_3293c|M.abscessus_ATCC_199 VPFEIDDYTRWRLLEGLDDIGLTLRKVDEIAAFEAARPEFKPRTLEPSE : * ***:: **********.*.*** *.* :* . :**:*