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M. thermoresistible (build 8) TH_1814 (serB2)

annotation: PROBABLE PHOSPHOSERINE PHOSPHATASE SERB2 (PSP) (O-PHOSPHOSERINE PHOSPHOHYDROLASE) (PSPASE)
coordinates: 3550143 - 3551429
length: 429

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1814serB2-100% (429)PROBABLE PHOSPHOSERINE PHOSPHATASE SERB2 (PSP) (O-PHOSPHOSERINE PHOSPHOHYDROLASE) (PSPASE)
M. thermoresistible (build 8)TH_3424-2e-1327.54% (207) PUTATIVE HAD-superfamily subfamily IB hydrolase, TIGR01490
M. thermoresistible (build 8)TH_0497-1e-1126.37% (201) POSSIBLE TRANSMEMBRANE PHOSPHOLIPID BIOSYNTHESIS BIFUNCTIONNAL

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3068cserB21e-17779.36% (407) phosphoserine phosphatase
M. gilvum PYR-GCKMflv_4276-0.082.18% (404) phosphoserine phosphatase SerB
M. tuberculosis H37RvRv3042cserB21e-17679.12% (407) phosphoserine phosphatase
M. leprae Br4923MLBr_01727-1e-17478.38% (407) putative phosphoserine phosphatase
M. abscessus ATCC 19977MAB_3388c-1e-16373.28% (408) phosphoserine phosphatase (SerB2)
M. marinum MMMAR_1652serB21e-17778.38% (407) phosphoserine phosphatase SerB2
M. avium 104MAV_3907serB1e-17879.36% (407) phosphoserine phosphatase SerB
M. smegmatis MC2 155MSMEG_2321serB0.085.78% (408) phosphoserine phosphatase
M. ulcerans Agy99MUL_1888serB21e-17678.13% (407) phosphoserine phosphatase SerB2
M. vanbaalenii PYR-1Mvan_2083-0.082.57% (413) phosphoserine phosphatase SerB

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4276|M.gilvum_PYR-GCK          -------MVDLS---------GSSVLITVTGRDQPGVTSALFEVLSRYGV
Mvan_2083|M.vanbaalenii_PYR-1       -------MSASQNWPAGSSRDRSSLLITVTGRDQPGVTSALFEVLSRHRV
MSMEG_2321|M.smegmatis_MC2_155      -------MSSAR--------ERSSLLITVTGVDQPGVTSALFEVLSRHKV
TH_1814|M.thermoresistible__bu      MAGPTNKKVPTEKVPKKVPKKKVSVLITVTGVDQPGVTSALFEVLARHRV
MLBr_01727|M.leprae_Br4923          -------MNTPP---------KVSVLITVTGVDQPGVTSALFAVLSRHGG
MAV_3907|M.avium_104                -------MNSPP---------KVSVLITVTGVDQPGVTATLFEVLSGHGV
Mb3068c|M.bovis_AF2122/97           ---------MPA---------KVSVLITVTGMDQPGVTSALFEVLAQHGV
Rv3042c|M.tuberculosis_H37Rv        ---------MPA---------KVSVLITVTGMDQPGVTSALFEVLAQHGV
MMAR_1652|M.marinum_M               -------MSVPA---------KVSVLITVTGIDQPGVTSALFEVLSKHGV
MUL_1888|M.ulcerans_Agy99           ---------MPA---------KVSVLITVTGIDQPGVTSALFEVLSKHGV
MAB_3388c|M.abscessus_ATCC_199      -------MNN-----------RVTVLVTVTGADKPGVTSVLMGVLSRHGV
                                                           ::*:**** *:****:.*: **: :  

Mflv_4276|M.gilvum_PYR-GCK          TLLNVEQVVIRNRLTLGVLVAAAPDVAAGAQFREDVEAAIHGVGLEVTIE
Mvan_2083|M.vanbaalenii_PYR-1       DLLNVEQVVIRGRLTLGVLVAAATEVAAGAELRSEVEAAIHGVGLDVSIE
MSMEG_2321|M.smegmatis_MC2_155      ELRNVEQVVIRGRLTLGVLVAAPSDVADGDDLRRDVEAAIHGVGLDVAIE
TH_1814|M.thermoresistible__bu      SLLNVEQVVIRGRLTLGVLLAAPPEVADGPALRAEVREAIHRVGLDVTIE
MLBr_01727|M.leprae_Br4923          ELLNVEQVVIRGRLTLGVLVLCPPEVAAYTALRDDVQAAIRRVGLDVTIE
MAV_3907|M.avium_104                ELLNVEQVVIRHRLTLGVLVCCPADVADGPALRHDVEAAIRKVGLDVSIE
Mb3068c|M.bovis_AF2122/97           ELLNVEQVVIRGRLTLGVLVSCPLDVADGTALRDDVASAIHGVGLDVAIE
Rv3042c|M.tuberculosis_H37Rv        ELLNVEQVVIRGRLTLGVLVSCPLDVADGTALRDDVAAAIHGVGLDVAIE
MMAR_1652|M.marinum_M               ELLNVEQVVIRSRLTLGVLVSCAPEVADGAALREDVEAAIHEVGLDVTVE
MUL_1888|M.ulcerans_Agy99           ELLNVEQVVIRRRLTLGVLVSCAPEVADGGALREDVEAAIHEVGLDVTVE
MAB_3388c|M.abscessus_ATCC_199      DLLNVEQVVIRGKLTLGVLVKAQGRSDAVEALQDELEEAMHTLGFDVDVE
                                     * ******** :******: .         :: ::  *:: :*::* :*

Mflv_4276|M.gilvum_PYR-GCK          GSNGLPVMQVPSTHTIVVLGRPITAEAFGVVAREVAELGVNIDFIRGVSD
Mvan_2083|M.vanbaalenii_PYR-1       SSDGLPVLRVPSTHTIVVLGRPITAEAFGVVAREAAALGVNIDFIRGVSD
MSMEG_2321|M.smegmatis_MC2_155      RSDDLPVMREPSTHTIVVLGRPITAEAFGVVARAVADLGVNIDFIRGVSD
TH_1814|M.thermoresistible__bu      RSDDLPVMDEPSSHTITVLGRPITAQAFSAVAREVAALGVNIDSIRGVSD
MLBr_01727|M.leprae_Br4923          RSDDLPIIREPSTHTIFVLGRPITARAFGAVAREVAALDVNIDVIRGISD
MAV_3907|M.avium_104                RSDDVPIIREPSTHTIFVLGRPITAAAFGAVAREVAALGVNIDLIRGVSD
Mb3068c|M.bovis_AF2122/97           RSDDLPIIRQPSTHTIFVLGRPITAGAFSAVAREVAALGVNIDFIRGISD
Rv3042c|M.tuberculosis_H37Rv        RSDDLPIIRQPSTHTIFVLGRPITAGAFSAVARGVAALGVNIDFIRGISD
MMAR_1652|M.marinum_M               RSDDLPVIREPSTHTIFVLGRPVTAGAFGAVAKEVAALGVNIDFIRGISD
MUL_1888|M.ulcerans_Agy99           RSDDLPVIREPSTHTIFVLGRPVTAGAFGAVAKEVAALGVNIDFIRGISD
MAB_3388c|M.abscessus_ATCC_199      FGGDSSVIKDPSTHTIVVLGRPVTARAFGAVARELAALGINIDLIRGIAD
                                     ... .::  **:*** *****:** **..**:  * *.:*** ***::*

Mflv_4276|M.gilvum_PYR-GCK          YPVTGLELRVSVPNG--VYGDLQRVLARLSAEEAVDIAVEDYSLARRAKR
Mvan_2083|M.vanbaalenii_PYR-1       YPVTGLELRVSVPPG--AYRELQAVLARVAVEESVDIAVEDYSLSRRAKR
MSMEG_2321|M.smegmatis_MC2_155      YPVTGLELRVSVPAGA-AYGQLQQALATVAANEGVDIALEDYTLSRRAKR
TH_1814|M.thermoresistible__bu      YPVTGLKLQVSVPEGA-DYDQLQRNLAQVAVDEAVDIALEDYSLSRRAKR
MLBr_01727|M.leprae_Br4923          YPVTGLELRVSAPLE--AAGSLRTALNRVATEEHVDVAVEGYGLARRIKR
MAV_3907|M.avium_104                YPVIGLELRVSVPPG--ADGALRTALNRVSSEEHVDVAVEDYTLERRAKR
Mb3068c|M.bovis_AF2122/97           YPVTGLELRVSVPPG--CVGPLQIALTKVAAEEHVDVAVEDYGLAWRTKR
Rv3042c|M.tuberculosis_H37Rv        YPVTGLELRVSVPPG--CVGPLQIALTKVAAEEHVDVAVEDYGLAWRTKR
MMAR_1652|M.marinum_M               YPVTGLELRVSVPPG--TYRPLQTALTKVAVDERVDVAVEDYGLAWRTKR
MUL_1888|M.ulcerans_Agy99           YPVTGLELRVSVPPG--TYRPLQTALTKVAVDERVDVAVEDYGLAWRTKR
MAB_3388c|M.abscessus_ATCC_199      YPVTGLELRVTVPQNRLTDVDLHTAMAQVATDEPVDIAVEHSSLDRRAKR
                                    *** **:*:*:.*        *:  :  :: :* **:*:*   *  * **

Mflv_4276|M.gilvum_PYR-GCK          LIVFDVDSTLIQGEVIEMLAAHAGAEAAVAEVTEAAMRGELDFAESLHRR
Mvan_2083|M.vanbaalenii_PYR-1       LIVFDVDSTLIQGEVIEMLAAHAGAEAAVAEVTEAAMRGELDFAESLHRR
MSMEG_2321|M.smegmatis_MC2_155      LIVFDVDSTLIQGEVIEMLAEHAGAAAAVAEVTEAAMRGELDFAESLHRR
TH_1814|M.thermoresistible__bu      LIVFDVDSTLIQGEVIEMLAERAGAGAAVAAVTEAAMRGELDFAESLHQR
MLBr_01727|M.leprae_Br4923          LIVFDVDSTLVQGEVIEMLAARAGAQGTVAAITEAAMRGELDFAESLQQR
MAV_3907|M.avium_104                LIVFDVDSTLVQGEVIEMLAAKAGAEGQVAAITDAAMRGELDFAQSLQQR
Mb3068c|M.bovis_AF2122/97           LIVFDVDSTLVQGEVIEMLAARAGAQGQVAAITEAAMRGELDFAESLQRR
Rv3042c|M.tuberculosis_H37Rv        LIVFDVDSTLVQGEVIEMLAARAGAQGQVAAITEAAMRGELDFAESLQRR
MMAR_1652|M.marinum_M               LIVFDVDSTLVQGEVIEMLAARAGAEGTVAAITEAAMRGELDFAQSLQQR
MUL_1888|M.ulcerans_Agy99           LIVFDVDSTLVQGEVIEMLAARAGAEGTVAAITEAAIRGELDFAQSLQQR
MAB_3388c|M.abscessus_ATCC_199      LIVFDVDSTLIQGEVIEMLADRAGAREQVAAITEAAMRGELDFAQSLHQR
                                    **********:********* :***   ** :*:**:*******:**::*

Mflv_4276|M.gilvum_PYR-GCK          VATLAGLPAEVVDEVAAKLELTPGARTTIRTLRRLGYHCGVVSGGFRQVI
Mvan_2083|M.vanbaalenii_PYR-1       VATLAGLPASVLDDVADQIELTPGARTTLRTLRRLGYHCGIVSGGFRQVI
MSMEG_2321|M.smegmatis_MC2_155      VATLAGLPASVLDEVAEQLELTPGARTTIRTLRRLGYYCGVVSGGFRQVI
TH_1814|M.thermoresistible__bu      VANLAGLPAEVLDEVAEQIELTPGARTTLRTLRRLGYYCGVVSGGFRQVI
MLBr_01727|M.leprae_Br4923          VATLAGLPVTVVDEVANQLQLMPGARTTLRTLRRLGFRCGVVSGGFRRII
MAV_3907|M.avium_104                VATLAGLPATVIDEVAGQLELMPGARTTLRTLRRLGYACGVVSGGFRRII
Mb3068c|M.bovis_AF2122/97           VATLAGLPATVIDDVAEQLELMPGARTTIRTLRRLGFRCGVVSGGFRRII
Rv3042c|M.tuberculosis_H37Rv        VATLAGLPATVIDDVAEQLELMPGARTTIRTLRRLGFRCGVVSGGFRRII
MMAR_1652|M.marinum_M               VATLEGLPATVIDDVAAQLQLMPGARTTLRTLQRLGFRCGVVSGGFRRII
MUL_1888|M.ulcerans_Agy99           VATLEGLPATVIDDVAAQLQLMPGARTTLRTLQRLGFRCGVVSGGFRRII
MAB_3388c|M.abscessus_ATCC_199      VATLAGLPESVLEDVADELVLTPGARTTIRTLRRLGYSCGVVSGGFRQVI
                                    **.* ***  *:::** :: * ******:***:***: **:******::*

Mflv_4276|M.gilvum_PYR-GCK          QPLADDLMLDYVAANHLEIVDGKLTGRVIGPVIDRAAKAKALRDFAAQVG
Mvan_2083|M.vanbaalenii_PYR-1       EPLAHELMMDFVAANELEIVDGKLTGRVVGDVVDRPGKAKALRDFAQQAG
MSMEG_2321|M.smegmatis_MC2_155      EPLAHELMLDYVAANELEIVDGKLTGRVVGDVVDRPGKAKALRDFAQQVG
TH_1814|M.thermoresistible__bu      EPLAHELMLDYVAANELEIVDGKLTGRVIGPVIDRAGKAKALRDFAQQVG
MLBr_01727|M.leprae_Br4923          EPLAHELMLDFVAANELEIVDGILTGRVVGTIVDRPGKAKALRYFSEQAG
MAV_3907|M.avium_104                EPLAEELMLDYVAANELEIVDGTLTGRVVGPIIDRAGKATALREFAQRAG
Mb3068c|M.bovis_AF2122/97           EPLARELMLDFVASNELEIVDGILTGRVVGPIVDRPGKAKALRDFASQYG
Rv3042c|M.tuberculosis_H37Rv        EPLARELMLDFVASNELEIVDGILTGRVVGPIVDRPGKAKALRDFASQYG
MMAR_1652|M.marinum_M               EPLAQELNLDFVAANELEIIDGTLTGRVVGSIVDRPGKAAALREFAGRFG
MUL_1888|M.ulcerans_Agy99           EPLAQELNLDFVAANELEIIDGTLTGRVVGSIVDRPGKAAALREFAGRFG
MAB_3388c|M.abscessus_ATCC_199      DPLAHELALDFVAANVLEIVDGKLTGRVIGEVVDRPGKAKALRQFAYEAG
                                    :*** :* :*:**:* ***:** *****:* ::**..** *** *: . *

Mflv_4276|M.gilvum_PYR-GCK          VPMQQTVAVGDGANDIDMLSAAGLGVAFNAKPALREVADASLNHPYLDTV
Mvan_2083|M.vanbaalenii_PYR-1       VPMEQTVAVGDGANDIDMLSAAGLGVAFNAKPALREVADASLSYPYLDTL
MSMEG_2321|M.smegmatis_MC2_155      VPMEQTVAVGDGANDIDMLSAAGLGVAFNAKPALREVADASLSHPYLDTV
TH_1814|M.thermoresistible__bu      VPMEQTVAVGDGANDIDMLAAAGLGVAFNAKPALREVADASLSHPYLDTV
MLBr_01727|M.leprae_Br4923          VPMEQTVAVGDGANDIDMLTAAGLGIAFNAKPALRAVADASLSHPYLDTV
MAV_3907|M.avium_104                VPMAQTVAVGDGANDIDMLAAAGLGIAFNAKPALREVADASLSHPYLDTV
Mb3068c|M.bovis_AF2122/97           VPMEQTVAVGDGANDIDMLGAAGLGIAFNAKPALREVADASLSHPYLDTV
Rv3042c|M.tuberculosis_H37Rv        VPMEQTVAVGDGANDIDMLGAAGLGIAFNAKPALREVADASLSHPYLDTV
MMAR_1652|M.marinum_M               VPMEQTVAVGDGANDIDMLAAAGLGVAFNAKPALRAVADASLSHPYLDTV
MUL_1888|M.ulcerans_Agy99           VPMEQTVAVGDGANDIDMLAAAGLGVAFNAKPALRAVADASLSHPYLDTV
MAB_3388c|M.abscessus_ATCC_199      VPLAQTVAVGDGANDIDMLSAAGLGVAFNAKPALRKVADASVSQPYLDVV
                                    **: *************** *****:********* *****:. ****.:

Mflv_4276|M.gilvum_PYR-GCK          LFILGITRGEIEAADALDGVVRRVDIPD-
Mvan_2083|M.vanbaalenii_PYR-1       LFILGITRGEIEAADALDGVVRRVEIPD-
MSMEG_2321|M.smegmatis_MC2_155      LFILGITRGEIEAADALDGVVRRVEIPDY
TH_1814|M.thermoresistible__bu      LFILGVTRAEIEAADAVDGVLRRVEIPDD
MLBr_01727|M.leprae_Br4923          LFVLGVTRGEIEAADAADGGVRRVEIPPD
MAV_3907|M.avium_104                LFLLGVTRGEIEAADAIDGEVRRVEIPPE
Mb3068c|M.bovis_AF2122/97           LFLLGVTRGEIEAADAGDCGVRRVEIPAD
Rv3042c|M.tuberculosis_H37Rv        LFLLGVTRGEIEAADAGDCGVRRVEIPAD
MMAR_1652|M.marinum_M               LFLLGVTRGEIEAADNVDGVMRRVEIPED
MUL_1888|M.ulcerans_Agy99           LFLLGVTRGEIEAADNVDGVMRRVEIPED
MAB_3388c|M.abscessus_ATCC_199      LFILGITRAEIEAADAVDGGVRRVDIPDD
                                    **:**:**.******  *  :***:**