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VPAKVSVLITVTGIDQPGVTSALFEVLSKHGVELLNVEQVVIRRRLTLGVLVSCAPEVADGGALREDVEA AIHEVGLDVTVERSDDLPVIREPSTHTIFVLGRPVTAGAFGAVAKEVAALGVNIDFIRGISDYPVTGLEL RVSVPPGTYRPLQTALTKVAVDERVDVAVEDYGLAWRTKRLIVFDVDSTLVQGEVIEMLAARAGAEGTVA AITEAAIRGELDFAQSLQQRVATLEGLPATVIDDVAAQLQLMPGARTTLRTLQRLGFRCGVVSGGFRRII EPLAQELNLDFVAANELEIIDGTLTGRVVGSIVDRPGKAAALREFAGRFGVPMEQTVAVGDGANDIDMLA AAGLGVAFNAKPALRAVADASLSHPYLDTVLFLLGVTRGEIEAADNVDGVMRRVEIPED
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1888 | serB2 | - | 100% (409) | phosphoserine phosphatase SerB2 |
| M. ulcerans Agy99 | MUL_4577 | serB1 | 2e-14 | 30.73% (205) | phosphoserine phosphatase SerB1 |
| M. ulcerans Agy99 | MUL_3764 | plsC | 1e-10 | 25.87% (201) | bifunctional transmembrane phospholipid biosynthesis enzyme |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3068c | serB2 | 0.0 | 86.06% (409) | phosphoserine phosphatase |
| M. gilvum PYR-GCK | Mflv_4276 | - | 1e-173 | 75.68% (403) | phosphoserine phosphatase SerB |
| M. tuberculosis H37Rv | Rv3042c | serB2 | 0.0 | 86.06% (409) | phosphoserine phosphatase |
| M. leprae Br4923 | MLBr_01727 | - | 0.0 | 83.82% (408) | putative phosphoserine phosphatase |
| M. abscessus ATCC 19977 | MAB_3388c | - | 1e-157 | 71.08% (408) | phosphoserine phosphatase (SerB2) |
| M. marinum M | MMAR_1652 | serB2 | 0.0 | 99.27% (409) | phosphoserine phosphatase SerB2 |
| M. avium 104 | MAV_3907 | serB | 0.0 | 83.09% (408) | phosphoserine phosphatase SerB |
| M. smegmatis MC2 155 | MSMEG_2321 | serB | 1e-175 | 78.22% (404) | phosphoserine phosphatase |
| M. thermoresistible (build 8) | TH_1814 | serB2 | 1e-176 | 78.13% (407) | PROBABLE PHOSPHOSERINE PHOSPHATASE SERB2 (PSP) |
| M. vanbaalenii PYR-1 | Mvan_2083 | - | 1e-178 | 78.66% (403) | phosphoserine phosphatase SerB |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4276|M.gilvum_PYR-GCK -------MVDLS---------GSSVLITVTGRDQPGVTSALFEVLSRYGV
Mvan_2083|M.vanbaalenii_PYR-1 -------MSASQNWPAGSSRDRSSLLITVTGRDQPGVTSALFEVLSRHRV
MSMEG_2321|M.smegmatis_MC2_155 -------MSSAR--------ERSSLLITVTGVDQPGVTSALFEVLSRHKV
TH_1814|M.thermoresistible__bu MAGPTNKKVPTEKVPKKVPKKKVSVLITVTGVDQPGVTSALFEVLARHRV
MUL_1888|M.ulcerans_Agy99 ---------MPA---------KVSVLITVTGIDQPGVTSALFEVLSKHGV
MMAR_1652|M.marinum_M -------MSVPA---------KVSVLITVTGIDQPGVTSALFEVLSKHGV
Mb3068c|M.bovis_AF2122/97 ---------MPA---------KVSVLITVTGMDQPGVTSALFEVLAQHGV
Rv3042c|M.tuberculosis_H37Rv ---------MPA---------KVSVLITVTGMDQPGVTSALFEVLAQHGV
MLBr_01727|M.leprae_Br4923 -------MNTPP---------KVSVLITVTGVDQPGVTSALFAVLSRHGG
MAV_3907|M.avium_104 -------MNSPP---------KVSVLITVTGVDQPGVTATLFEVLSGHGV
MAB_3388c|M.abscessus_ATCC_199 -------MNN-----------RVTVLVTVTGADKPGVTSVLMGVLSRHGV
::*:**** *:****:.*: **: :
Mflv_4276|M.gilvum_PYR-GCK TLLNVEQVVIRNRLTLGVLVAAAPDVAAGAQFREDVEAAIHGVGLEVTIE
Mvan_2083|M.vanbaalenii_PYR-1 DLLNVEQVVIRGRLTLGVLVAAATEVAAGAELRSEVEAAIHGVGLDVSIE
MSMEG_2321|M.smegmatis_MC2_155 ELRNVEQVVIRGRLTLGVLVAAPSDVADGDDLRRDVEAAIHGVGLDVAIE
TH_1814|M.thermoresistible__bu SLLNVEQVVIRGRLTLGVLLAAPPEVADGPALRAEVREAIHRVGLDVTIE
MUL_1888|M.ulcerans_Agy99 ELLNVEQVVIRRRLTLGVLVSCAPEVADGGALREDVEAAIHEVGLDVTVE
MMAR_1652|M.marinum_M ELLNVEQVVIRSRLTLGVLVSCAPEVADGAALREDVEAAIHEVGLDVTVE
Mb3068c|M.bovis_AF2122/97 ELLNVEQVVIRGRLTLGVLVSCPLDVADGTALRDDVASAIHGVGLDVAIE
Rv3042c|M.tuberculosis_H37Rv ELLNVEQVVIRGRLTLGVLVSCPLDVADGTALRDDVAAAIHGVGLDVAIE
MLBr_01727|M.leprae_Br4923 ELLNVEQVVIRGRLTLGVLVLCPPEVAAYTALRDDVQAAIRRVGLDVTIE
MAV_3907|M.avium_104 ELLNVEQVVIRHRLTLGVLVCCPADVADGPALRHDVEAAIRKVGLDVSIE
MAB_3388c|M.abscessus_ATCC_199 DLLNVEQVVIRGKLTLGVLVKAQGRSDAVEALQDELEEAMHTLGFDVDVE
* ******** :******: . :: :: *:: :*::* :*
Mflv_4276|M.gilvum_PYR-GCK GSNGLPVMQVPSTHTIVVLGRPITAEAFGVVAREVAELGVNIDFIRGVSD
Mvan_2083|M.vanbaalenii_PYR-1 SSDGLPVLRVPSTHTIVVLGRPITAEAFGVVAREAAALGVNIDFIRGVSD
MSMEG_2321|M.smegmatis_MC2_155 RSDDLPVMREPSTHTIVVLGRPITAEAFGVVARAVADLGVNIDFIRGVSD
TH_1814|M.thermoresistible__bu RSDDLPVMDEPSSHTITVLGRPITAQAFSAVAREVAALGVNIDSIRGVSD
MUL_1888|M.ulcerans_Agy99 RSDDLPVIREPSTHTIFVLGRPVTAGAFGAVAKEVAALGVNIDFIRGISD
MMAR_1652|M.marinum_M RSDDLPVIREPSTHTIFVLGRPVTAGAFGAVAKEVAALGVNIDFIRGISD
Mb3068c|M.bovis_AF2122/97 RSDDLPIIRQPSTHTIFVLGRPITAGAFSAVAREVAALGVNIDFIRGISD
Rv3042c|M.tuberculosis_H37Rv RSDDLPIIRQPSTHTIFVLGRPITAGAFSAVARGVAALGVNIDFIRGISD
MLBr_01727|M.leprae_Br4923 RSDDLPIIREPSTHTIFVLGRPITARAFGAVAREVAALDVNIDVIRGISD
MAV_3907|M.avium_104 RSDDVPIIREPSTHTIFVLGRPITAAAFGAVAREVAALGVNIDLIRGVSD
MAB_3388c|M.abscessus_ATCC_199 FGGDSSVIKDPSTHTIVVLGRPVTARAFGAVARELAALGINIDLIRGIAD
... .:: **:*** *****:** **..**: * *.:*** ***::*
Mflv_4276|M.gilvum_PYR-GCK YPVTGLELRVSVPNG--VYGDLQRVLARLSAEEAVDIAVEDYSLARRAKR
Mvan_2083|M.vanbaalenii_PYR-1 YPVTGLELRVSVPPG--AYRELQAVLARVAVEESVDIAVEDYSLSRRAKR
MSMEG_2321|M.smegmatis_MC2_155 YPVTGLELRVSVPAGA-AYGQLQQALATVAANEGVDIALEDYTLSRRAKR
TH_1814|M.thermoresistible__bu YPVTGLKLQVSVPEGA-DYDQLQRNLAQVAVDEAVDIALEDYSLSRRAKR
MUL_1888|M.ulcerans_Agy99 YPVTGLELRVSVPPG--TYRPLQTALTKVAVDERVDVAVEDYGLAWRTKR
MMAR_1652|M.marinum_M YPVTGLELRVSVPPG--TYRPLQTALTKVAVDERVDVAVEDYGLAWRTKR
Mb3068c|M.bovis_AF2122/97 YPVTGLELRVSVPPG--CVGPLQIALTKVAAEEHVDVAVEDYGLAWRTKR
Rv3042c|M.tuberculosis_H37Rv YPVTGLELRVSVPPG--CVGPLQIALTKVAAEEHVDVAVEDYGLAWRTKR
MLBr_01727|M.leprae_Br4923 YPVTGLELRVSAPLE--AAGSLRTALNRVATEEHVDVAVEGYGLARRIKR
MAV_3907|M.avium_104 YPVIGLELRVSVPPG--ADGALRTALNRVSSEEHVDVAVEDYTLERRAKR
MAB_3388c|M.abscessus_ATCC_199 YPVTGLELRVTVPQNRLTDVDLHTAMAQVATDEPVDIAVEHSSLDRRAKR
*** **:*:*:.* *: : :: :* **:*:* * * **
Mflv_4276|M.gilvum_PYR-GCK LIVFDVDSTLIQGEVIEMLAAHAGAEAAVAEVTEAAMRGELDFAESLHRR
Mvan_2083|M.vanbaalenii_PYR-1 LIVFDVDSTLIQGEVIEMLAAHAGAEAAVAEVTEAAMRGELDFAESLHRR
MSMEG_2321|M.smegmatis_MC2_155 LIVFDVDSTLIQGEVIEMLAEHAGAAAAVAEVTEAAMRGELDFAESLHRR
TH_1814|M.thermoresistible__bu LIVFDVDSTLIQGEVIEMLAERAGAGAAVAAVTEAAMRGELDFAESLHQR
MUL_1888|M.ulcerans_Agy99 LIVFDVDSTLVQGEVIEMLAARAGAEGTVAAITEAAIRGELDFAQSLQQR
MMAR_1652|M.marinum_M LIVFDVDSTLVQGEVIEMLAARAGAEGTVAAITEAAMRGELDFAQSLQQR
Mb3068c|M.bovis_AF2122/97 LIVFDVDSTLVQGEVIEMLAARAGAQGQVAAITEAAMRGELDFAESLQRR
Rv3042c|M.tuberculosis_H37Rv LIVFDVDSTLVQGEVIEMLAARAGAQGQVAAITEAAMRGELDFAESLQRR
MLBr_01727|M.leprae_Br4923 LIVFDVDSTLVQGEVIEMLAARAGAQGTVAAITEAAMRGELDFAESLQQR
MAV_3907|M.avium_104 LIVFDVDSTLVQGEVIEMLAAKAGAEGQVAAITDAAMRGELDFAQSLQQR
MAB_3388c|M.abscessus_ATCC_199 LIVFDVDSTLIQGEVIEMLADRAGAREQVAAITEAAMRGELDFAQSLHQR
**********:********* :*** ** :*:**:*******:**::*
Mflv_4276|M.gilvum_PYR-GCK VATLAGLPAEVVDEVAAKLELTPGARTTIRTLRRLGYHCGVVSGGFRQVI
Mvan_2083|M.vanbaalenii_PYR-1 VATLAGLPASVLDDVADQIELTPGARTTLRTLRRLGYHCGIVSGGFRQVI
MSMEG_2321|M.smegmatis_MC2_155 VATLAGLPASVLDEVAEQLELTPGARTTIRTLRRLGYYCGVVSGGFRQVI
TH_1814|M.thermoresistible__bu VANLAGLPAEVLDEVAEQIELTPGARTTLRTLRRLGYYCGVVSGGFRQVI
MUL_1888|M.ulcerans_Agy99 VATLEGLPATVIDDVAAQLQLMPGARTTLRTLQRLGFRCGVVSGGFRRII
MMAR_1652|M.marinum_M VATLEGLPATVIDDVAAQLQLMPGARTTLRTLQRLGFRCGVVSGGFRRII
Mb3068c|M.bovis_AF2122/97 VATLAGLPATVIDDVAEQLELMPGARTTIRTLRRLGFRCGVVSGGFRRII
Rv3042c|M.tuberculosis_H37Rv VATLAGLPATVIDDVAEQLELMPGARTTIRTLRRLGFRCGVVSGGFRRII
MLBr_01727|M.leprae_Br4923 VATLAGLPVTVVDEVANQLQLMPGARTTLRTLRRLGFRCGVVSGGFRRII
MAV_3907|M.avium_104 VATLAGLPATVIDEVAGQLELMPGARTTLRTLRRLGYACGVVSGGFRRII
MAB_3388c|M.abscessus_ATCC_199 VATLAGLPESVLEDVADELVLTPGARTTIRTLRRLGYSCGVVSGGFRQVI
**.* *** *:::** :: * ******:***:***: **:******::*
Mflv_4276|M.gilvum_PYR-GCK QPLADDLMLDYVAANHLEIVDGKLTGRVIGPVIDRAAKAKALRDFAAQVG
Mvan_2083|M.vanbaalenii_PYR-1 EPLAHELMMDFVAANELEIVDGKLTGRVVGDVVDRPGKAKALRDFAQQAG
MSMEG_2321|M.smegmatis_MC2_155 EPLAHELMLDYVAANELEIVDGKLTGRVVGDVVDRPGKAKALRDFAQQVG
TH_1814|M.thermoresistible__bu EPLAHELMLDYVAANELEIVDGKLTGRVIGPVIDRAGKAKALRDFAQQVG
MUL_1888|M.ulcerans_Agy99 EPLAQELNLDFVAANELEIIDGTLTGRVVGSIVDRPGKAAALREFAGRFG
MMAR_1652|M.marinum_M EPLAQELNLDFVAANELEIIDGTLTGRVVGSIVDRPGKAAALREFAGRFG
Mb3068c|M.bovis_AF2122/97 EPLARELMLDFVASNELEIVDGILTGRVVGPIVDRPGKAKALRDFASQYG
Rv3042c|M.tuberculosis_H37Rv EPLARELMLDFVASNELEIVDGILTGRVVGPIVDRPGKAKALRDFASQYG
MLBr_01727|M.leprae_Br4923 EPLAHELMLDFVAANELEIVDGILTGRVVGTIVDRPGKAKALRYFSEQAG
MAV_3907|M.avium_104 EPLAEELMLDYVAANELEIVDGTLTGRVVGPIIDRAGKATALREFAQRAG
MAB_3388c|M.abscessus_ATCC_199 DPLAHELALDFVAANVLEIVDGKLTGRVIGEVVDRPGKAKALRQFAYEAG
:*** :* :*:**:* ***:** *****:* ::**..** *** *: . *
Mflv_4276|M.gilvum_PYR-GCK VPMQQTVAVGDGANDIDMLSAAGLGVAFNAKPALREVADASLNHPYLDTV
Mvan_2083|M.vanbaalenii_PYR-1 VPMEQTVAVGDGANDIDMLSAAGLGVAFNAKPALREVADASLSYPYLDTL
MSMEG_2321|M.smegmatis_MC2_155 VPMEQTVAVGDGANDIDMLSAAGLGVAFNAKPALREVADASLSHPYLDTV
TH_1814|M.thermoresistible__bu VPMEQTVAVGDGANDIDMLAAAGLGVAFNAKPALREVADASLSHPYLDTV
MUL_1888|M.ulcerans_Agy99 VPMEQTVAVGDGANDIDMLAAAGLGVAFNAKPALRAVADASLSHPYLDTV
MMAR_1652|M.marinum_M VPMEQTVAVGDGANDIDMLAAAGLGVAFNAKPALRAVADASLSHPYLDTV
Mb3068c|M.bovis_AF2122/97 VPMEQTVAVGDGANDIDMLGAAGLGIAFNAKPALREVADASLSHPYLDTV
Rv3042c|M.tuberculosis_H37Rv VPMEQTVAVGDGANDIDMLGAAGLGIAFNAKPALREVADASLSHPYLDTV
MLBr_01727|M.leprae_Br4923 VPMEQTVAVGDGANDIDMLTAAGLGIAFNAKPALRAVADASLSHPYLDTV
MAV_3907|M.avium_104 VPMAQTVAVGDGANDIDMLAAAGLGIAFNAKPALREVADASLSHPYLDTV
MAB_3388c|M.abscessus_ATCC_199 VPLAQTVAVGDGANDIDMLSAAGLGVAFNAKPALRKVADASVSQPYLDVV
**: *************** *****:********* *****:. ****.:
Mflv_4276|M.gilvum_PYR-GCK LFILGITRGEIEAADALDGVVRRVDIPD-
Mvan_2083|M.vanbaalenii_PYR-1 LFILGITRGEIEAADALDGVVRRVEIPD-
MSMEG_2321|M.smegmatis_MC2_155 LFILGITRGEIEAADALDGVVRRVEIPDY
TH_1814|M.thermoresistible__bu LFILGVTRAEIEAADAVDGVLRRVEIPDD
MUL_1888|M.ulcerans_Agy99 LFLLGVTRGEIEAADNVDGVMRRVEIPED
MMAR_1652|M.marinum_M LFLLGVTRGEIEAADNVDGVMRRVEIPED
Mb3068c|M.bovis_AF2122/97 LFLLGVTRGEIEAADAGDCGVRRVEIPAD
Rv3042c|M.tuberculosis_H37Rv LFLLGVTRGEIEAADAGDCGVRRVEIPAD
MLBr_01727|M.leprae_Br4923 LFVLGVTRGEIEAADAADGGVRRVEIPPD
MAV_3907|M.avium_104 LFLLGVTRGEIEAADAIDGEVRRVEIPPE
MAB_3388c|M.abscessus_ATCC_199 LFILGITRAEIEAADAVDGGVRRVDIPDD
**:**:**.****** * :***:**