For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_1632 | ligB | - | 100% (522) | PROBABLE ATP-DEPENDENT DNA LIGASE LIGB (POLYDEOXYRIBONUCLEOTIDE SYNTHASE |
| M. thermoresistible (build 8) | TH_3391 | - | 2e-20 | 29.78% (319) | PUTATIVE ATP dependent DNA ligase |
| M. thermoresistible (build 8) | TH_3157 | - | 9e-14 | 27.49% (342) | PUTATIVE DNA ligase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3089 | ligB | 0.0 | 70.33% (509) | ATP-dependent DNA ligase |
| M. gilvum PYR-GCK | Mflv_4321 | ligB | 0.0 | 74.17% (511) | ATP-dependent DNA ligase |
| M. tuberculosis H37Rv | Rv3062 | ligB | 0.0 | 70.33% (509) | ATP-dependent DNA ligase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1033 | - | 1e-15 | 29.11% (316) | ATP-dependent DNA ligase |
| M. marinum M | MMAR_1623 | ligB | 0.0 | 71.86% (501) | ATP-dependent DNA ligase LigB |
| M. avium 104 | MAV_3937 | ligB | 0.0 | 73.06% (516) | ATP-dependent DNA ligase |
| M. smegmatis MC2 155 | MSMEG_2277 | ligB | 0.0 | 75.79% (508) | ATP-dependent DNA ligase |
| M. ulcerans Agy99 | MUL_3413 | ligB | 0.0 | 69.79% (513) | ATP-dependent DNA ligase |
| M. vanbaalenii PYR-1 | Mvan_2025 | ligB | 0.0 | 71.16% (534) | ATP-dependent DNA ligase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3089|M.bovis_AF2122/97 --------------------------------------------------
Rv3062|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1623|M.marinum_M --------------------------------------------------
MUL_3413|M.ulcerans_Agy99 --------------------------------------------------
MAV_3937|M.avium_104 --------------------------------------------------
TH_1632|M.thermoresistible__bu --------------------------------------------------
MSMEG_2277|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4321|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2025|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_1033|M.abscessus_ATCC_1997 MLYPATDTSPATTKADVFGYYTAIAPFMLPHIAGRPVTRKRWPNGIDQPS
Mb3089|M.bovis_AF2122/97 --------------------------------------------------
Rv3062|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1623|M.marinum_M --------------------------------------------------
MUL_3413|M.ulcerans_Agy99 --------------------------------------------------
MAV_3937|M.avium_104 --------------------------------------------------
TH_1632|M.thermoresistible__bu --------------------------------------------------
MSMEG_2277|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4321|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2025|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_1033|M.abscessus_ATCC_1997 FFEKDLASSAPDWLPRRRIEHKSRYVSYPLIDTSVALAWIAQQAALEVHV
Mb3089|M.bovis_AF2122/97 ---------------------------------------MLLHDVAITSM
Rv3062|M.tuberculosis_H37Rv ---------------------------------------MLLHDVAITSM
MMAR_1623|M.marinum_M --------------------------------------------------
MUL_3413|M.ulcerans_Agy99 ---------------------------------------MLLIDIASTSL
MAV_3937|M.avium_104 -----------------------------MSPSHAKLATVLLFDVATASA
TH_1632|M.thermoresistible__bu -------------------------MSARAGRRPCQADQMLLVDVATASA
MSMEG_2277|M.smegmatis_MC2_155 ----------------------------------------MLADVAAAST
Mflv_4321|M.gilvum_PYR-GCK ---------------------------------------MLLVDVAGASA
Mvan_2025|M.vanbaalenii_PYR-1 ---------------------------------------MLLVDVANASA
MAB_1033|M.abscessus_ATCC_1997 PQWRFAGENPGPATRLVFDLDPGEGVGMAQLAEVARAIRDVLADIGLTTF
Mb3089|M.bovis_AF2122/97 DVAATSSRLTKVARIAALLHRAAPDTQ--LVTIIVSWLSGELP----QRH
Rv3062|M.tuberculosis_H37Rv DVAATSSRLTKVARIAALLHRAAPDTQ--LVTIIVSWLSGELP----QRH
MMAR_1623|M.marinum_M -MGGTSSRLAKVERIAELLRAAAPDPE--LVAIVVAWLSGELR----QRQ
MUL_3413|M.ulcerans_Agy99 NVGGTSSRLAKVARIAEPLRAAAPDPE--LVAIVVAWLSGELR----QRQ
MAV_3937|M.avium_104 DVGGTPSRLTKVARIADLLRRAAPDAA--LVAIVVSWLSGELR----QRQ
TH_1632|M.thermoresistible__bu EVGATTARSAKISRIAELLR----DTDAALVPVVVSWLSGELP----QRP
MSMEG_2277|M.smegmatis_MC2_155 EVAASSARLVKIERIATLLARSAAEDDTQAVAVIVSWLSGELP----QRQ
Mflv_4321|M.gilvum_PYR-GCK DVAASSARLAKIARIAELLRRAGRED----VAIVVSWLSGELT----QRQ
Mvan_2025|M.vanbaalenii_PYR-1 DVAAMSARLAKVARIAELLRTAGRQGDARLVRVVVSWLSGELT----QRQ
MAB_1033|M.abscessus_ATCC_1997 PVTSGSKGLHLYVPLAQPASSSGAVAVAKKVAVQLEQVMPDLVTATMTRQ
: . . :* * : : : :* *
Mb3089|M.bovis_AF2122/97 IGVGWAALRSLPPPAPQPALTVTGVDATLSKIGTLSGKGSQAQRAALVAE
Rv3062|M.tuberculosis_H37Rv IGVGWAALRSLPPPAPQPALTVTGVDATLSKIGTLPGKGSQAQRAALVAE
MMAR_1623|M.marinum_M IGVGWAALRSLPAAAGSPALTVTGTDAAFSEIGAVSGKGSAARRRELITR
MUL_3413|M.ulcerans_Agy99 IGVGWATLRSPPAAAGSPALTVTGTDAAFSEIGAVSGKGSAARRRELITR
MAV_3937|M.avium_104 IGVGWAALRSRPPAAAHPTLTVVAVDAAFAEIGAVAGKGAQARRAALLNA
TH_1632|M.thermoresistible__bu IGVGWAALRSLPPPAAAPTLTVAAVDAAFTQIRTVTGKGSQARRAALLAE
MSMEG_2277|M.smegmatis_MC2_155 IGVGWAALRTLPPPAATPSLTVDDVDDRLSTIKAVAGKGSQATRAGLVHE
Mflv_4321|M.gilvum_PYR-GCK IGVGWASLRSVPAAAAEPTLTVAEVERRFGEIGATAGRGSQARRAQLLAD
Mvan_2025|M.vanbaalenii_PYR-1 IGVGWRSVRSVPDPAAQPSLTVEDVDARFGEIGSTSGKGSQARRAALLAE
MAB_1033|M.abscessus_ATCC_1997 LRAGKVFVDWSQNSGSKTTVAPYSLRGRAVPTVAAPRTWEELDDPGLRQL
: .* : .. .::: : . *
Mb3089|M.bovis_AF2122/97 LFSAATEAEQT---FLLRLLGGELRQGAKGGIMADAVAQAAGLPAATVQR
Rv3062|M.tuberculosis_H37Rv LFSAATEAEQT---FLLRLLGGELRQGAKGGIMADAVAQAAGLPAATVQR
MMAR_1623|M.marinum_M LFAAATETEQA---FLVRLLSGELRQGALAGIMVDAVARAAEVPATAVQR
MUL_3413|M.ulcerans_Agy99 LFAASTETEQA---FLVRLLSGELRQGALAGIMVDAVARAAEVPATAVQR
MAV_3937|M.avium_104 LFAAATETEQT---FLLRLLGGELRQGALAGIMADAVARAAGIPAAAVQR
TH_1632|M.thermoresistible__bu LFGAATGIEQR---FLRGLLSGELRQGALVGVMADAVARAADVPAAAVRR
MSMEG_2277|M.smegmatis_MC2_155 LFSAATDPEQK---FLRHLLSGELRQGALAGVMADAVAKAAGLPAAEIRR
Mflv_4321|M.gilvum_PYR-GCK LFSAATDVEQT---FLRRLLTGELRQGALVGVMADAVAKAADLPAATVRR
Mvan_2025|M.vanbaalenii_PYR-1 LFAAATAVEQV---FLRRLLTGELRQGALGGVMADAVGKAAGVPSAVVRR
MAB_1033|M.abscessus_ATCC_1997 RYDEVLTRAQRDGDLLAGLDDVEIAEDRLSTYRSMRDPTRTPEPVPAVKP
: * :* * *: :. : * . ::
Mb3089|M.bovis_AF2122/97 AAMLGGDLAAAAAAGL---------SGAALDTFTLRVGRPIGPMLAQTAT
Rv3062|M.tuberculosis_H37Rv AAMLGGDLAAAAAAGL---------SGAALDTFTLRVGRPIGPMLAQTAT
MMAR_1623|M.marinum_M AAMLGGDLPTVAAACL---AAGSSGAAGALDSFTLRVGRPIGPMLAQSAG
MUL_3413|M.ulcerans_Agy99 AAMLGGDLPTVAAACL---AAGSSGAAGALDSFTLRVGRPIGPMLAQSAG
MAV_3937|M.avium_104 AAMLGGDLPAVAAAALSGEAAALSGEASALDAFTLRVGRPVAPMLAQTAA
TH_1632|M.thermoresistible__bu AAMLAGELPTVAGAALT-------GGTDALSRYTLRVGQPVGPMLAQTAA
MSMEG_2277|M.smegmatis_MC2_155 AAMLAGNLPAVAAAAVT-------GGRAALADFRLRVGRPVGPMLAQTAT
Mflv_4321|M.gilvum_PYR-GCK AAMLGGDLPAVAAAALT-------DGDAGLAQFTLQAGKAVGPMLAQTAA
Mvan_2025|M.vanbaalenii_PYR-1 AAMLGGDLPAVAAAAVT-------DGESALAQFTLQVGRPVGPMLAQTAT
MAB_1033|M.abscessus_ATCC_1997 EAGQDNSFVIQEHHATALHYDFRLERDGVLVSWAVPKNLPLEPSVNHLAV
* ..: * : : . .: * : : *
Mb3089|M.bovis_AF2122/97 SVHDALERHG----------------------------------------
Rv3062|M.tuberculosis_H37Rv SVHDALERHG----------------------------------------
MMAR_1623|M.marinum_M SITVALERHG----------------------------------------
MUL_3413|M.ulcerans_Agy99 SITDALERHG----------------------------------------
MAV_3937|M.avium_104 GVAEAIERHG----------------------------------------
TH_1632|M.thermoresistible__bu GVTEALERLG----------------------------------------
MSMEG_2277|M.smegmatis_MC2_155 SVDDALQRLG----------------------------------------
Mflv_4321|M.gilvum_PYR-GCK DVTDALDRLG----------------------------------------
Mvan_2025|M.vanbaalenii_PYR-1 GVADALDRFG----------------------------------------
MAB_1033|M.abscessus_ATCC_1997 HTEDHPLEYGSFEGTIPKGEYGAGEVTIWDSGTYDTEKFIDPRDDSGADG
. *
Mb3089|M.bovis_AF2122/97 --------------------------------------------------
Rv3062|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1623|M.marinum_M --------------------------------------------------
MUL_3413|M.ulcerans_Agy99 --------------------------------------------------
MAV_3937|M.avium_104 --------------------------------------------------
TH_1632|M.thermoresistible__bu --------------------------------------------------
MSMEG_2277|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4321|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2025|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_1033|M.abscessus_ATCC_1997 GQKGEVIVTLHGKRITGRYALIRTNGKQWLVHRMKDQRPAGSMPVGLAPM
Mb3089|M.bovis_AF2122/97 ------------GTTIFEAKLDGARVQIHRANDQVRIYTRSLDDVTARLP
Rv3062|M.tuberculosis_H37Rv ------------GTTIFEAKLDGARVQIHRANDQVRIYTRSLDDVTARLP
MMAR_1623|M.marinum_M ------------GATIFEAKLDGARVQIHRTGDEVTVYTRSLDDVTARLP
MUL_3413|M.ulcerans_Agy99 ------------GATIFEAKLDGARVQIHRTGDEVTVYTRSLDDVTARLP
MAV_3937|M.avium_104 ------------GQAIFEAKLDGARVQIHRAGDQVTVYTRSLDDVTARLP
TH_1632|M.thermoresistible__bu ------------GTAVLEAKLDGARVQIHRSRREVAIFTRSLDDVTARLP
MSMEG_2277|M.smegmatis_MC2_155 ------------GTAVLEAKLDGARVQIHRSGCDVSIYTRSLDDVTHRLP
Mflv_4321|M.gilvum_PYR-GCK ------------GTAMFEAKLDGARVQIHRRGDSVSIFTRSLDDVTARLP
Mvan_2025|M.vanbaalenii_PYR-1 ------------GTALFEAKLDGARVQIHRRGDAVSVFTRSLDDVTARLP
MAB_1033|M.abscessus_ATCC_1997 LPTTGSVAGLTAEEWAFEGKWDGYRLILECDRGQLRALARSGRDVTAEFP
:*.* ** *: :. : :** *** .:*
Mb3089|M.bovis_AF2122/97 EVVEATLALPVRDLVADGEAIALCPDNRPQRFQVTASRFGRSVDVAAARA
Rv3062|M.tuberculosis_H37Rv EVVEATLALPVRDLVADGEAIALCPDNRPQRFQVTASRFGRSVDVAAARA
MMAR_1623|M.marinum_M EVVQATLALPVSDLVADGEAIALQPDGRPHRFQVTASRFGRSVNVAAAQA
MUL_3413|M.ulcerans_Agy99 EVVQATLALPVSDLVADGEAIALQPDGRPHRFQVTASRFGRSVNVAAAQA
MAV_3937|M.avium_104 EVVTATLALPVEALIADGEAIALRPDNSPQRFQVTASRFGRSVDVAAAVA
TH_1632|M.thermoresistible__bu EVVEAALTWPVSEVIADAEAIALRPDGRPHRFQVTASRFGRAG----PGA
MSMEG_2277|M.smegmatis_MC2_155 EVVEATLALPATELIADAEAIALRPDGRPHLFQVTAARFGRKD----PGD
Mflv_4321|M.gilvum_PYR-GCK EVVEATLALPVTDLIADAEAIALRPDGRPHRFQVTASRFGRRGGTS-DTA
Mvan_2025|M.vanbaalenii_PYR-1 EVVDATLALPVTELIADAEAIALRPDGRPHRFQITASRFGRRGGTP-DAG
MAB_1033|M.abscessus_ATCC_1997 ALQRLAHELSDHRVVLDGEVVVPDRKGLPS-FALLQNRT----------P
: : . :: *.*.:. .. * * : *
Mb3089|M.bovis_AF2122/97 TQPLSVFFFDILHRDGTDLLEAPTTERLAALDALVPARHRVDRLITSDPT
Rv3062|M.tuberculosis_H37Rv TQPLSVFFFDILHRDGTDLLEAPTTERLAALDALVPARHRVDRLITSDPT
MMAR_1623|M.marinum_M KQPLSVFFFDILHRDGRDLLDAPTTDRLAALDAVVPARHRVDRLTTADAA
MUL_3413|M.ulcerans_Agy99 KQPLSVFFSDILHRDGRDLLDAPTTDRLAALDAVVPARHRVDRLTTADAA
MAV_3937|M.avium_104 AQPLSVFFFDILHCDGVDLLDAPTTDRLAALDALVPPAQRVDQLLTADPD
TH_1632|M.thermoresistible__bu APPLSVFVFDLLHVDGDDLLDRPTGARLEVLDALIPDRHRVDRLVTADPA
MSMEG_2277|M.smegmatis_MC2_155 LGPLSVFFFDLLHVDGRDLLDLPTEERFGALDALVRQDQRVDRLVTTDTV
Mflv_4321|M.gilvum_PYR-GCK SNPLSVFFFDLLHVDGVDLLDAPAHERIARLDAVTPDSQRVDRLVTSDPG
Mvan_2025|M.vanbaalenii_PYR-1 TQRLSVFFFDLLHADGVDLLDLPTGERIATLDATVPREQRVDRLLTSDPE
MAB_1033|M.abscessus_ATCC_1997 GADIRFWAFDLLYLDGKSLLRTKYRDRRRLLEVLVTGTESMTVPQQLS-G
: .: *:*: ** .** * *:. . : .
Mb3089|M.bovis_AF2122/97 DAANFLDATLAAGHEGVMAKAPAARYLAGRRGAGWLKVKPVHTLDLVVLA
Rv3062|M.tuberculosis_H37Rv DAANFLDATLAAGHEGVMAKAPAARYLAGRRGAGWLKVKPVHTLDLVVLA
MMAR_1623|M.marinum_M AATDFLRATLAAGHEGVMAKSPTAPYLAGRRGAGWLKVKPVHTLDLVVLA
MUL_3413|M.ulcerans_Agy99 AATDFLRATLAAGHEGVMAKSPTAPYLAGRRGAGWLKVKPVHTLDLVVLA
MAV_3937|M.avium_104 AAGRFLEATLAAGHEGVMAKAPGAPYQAGRRGAGWLKVKPVHTLDLVVLA
TH_1632|M.thermoresistible__bu AAERFLRATLDAGHEGVMAKSPSAAYEAGRRGAGWLKVKPVHTLDVVVLA
MSMEG_2277|M.smegmatis_MC2_155 AAQEFLERTLAAGHEGVMAKSPHAAYEAGRRGAGWLKVKPVHTLDLVVLA
Mflv_4321|M.gilvum_PYR-GCK AAQEFFDRTLAAGHEGVMAKSTVAPYEAGRRGAGWLKVKPVHTLDLVVLA
Mvan_2025|M.vanbaalenii_PYR-1 AAQAFLDATLAAGHEGVMAKSPTAPYEAGRRGAGWLKVKPVHTLDLVVLA
MAB_1033|M.abscessus_ATCC_1997 DGAAALAYSQDQGWEGVVAKRLDSTYVPGRTQS-WIKAKNWSSQEVVIGG
. : : * ***:** : * .** : *:*.* : ::*: .
Mb3089|M.bovis_AF2122/97 VEWGSGRRRGKLSNIHLGARDPATGGFVMVGKTFKGMTDAMLDWQTTRFH
Rv3062|M.tuberculosis_H37Rv VEWGSGRRRGKLSNIHLGARDPATGGFVMVGKTFKGMTDAMLDWQTTRFH
MMAR_1623|M.marinum_M VEWGSGRRRGKLSNIHLGARDAATGEFVMLGKTFKGMTDAMLDWQTARFT
MUL_3413|M.ulcerans_Agy99 VEWGSGRRRGKLSNIPLGARDAATGEFVMLGKTFKSMTDAMLDWQTARFT
MAV_3937|M.avium_104 VEWGSGRRRGKLSNIHLGARDPATGEFVMVGKTFKGMTDAMLDWQTARFT
TH_1632|M.thermoresistible__bu VEWGSGRRAGKLSNIHLGARDPRTGGFVMLGKTFKGMTDAMLEWQTARFL
MSMEG_2277|M.smegmatis_MC2_155 VEWGSGRRQGKLSNIHLGARDPDSSGFVMLGKTFKGMTDAMLEWQTQRFL
Mflv_4321|M.gilvum_PYR-GCK VEWGSGRRSGKLSNIHLGARDPGTGGFVMLGKTFKGMTDEMLAWQTRRFL
Mvan_2025|M.vanbaalenii_PYR-1 VEWGSGRRTGKLSNIHLGARDPATGGFVMLGKTFKGMTDEMLAWQTERFL
MAB_1033|M.abscessus_ATCC_1997 WRKGQGGRSSGIGSLLMG--IPVEGGLRYAGRVGTGFTERELSSLKERLE
. *.* * . :..: :* . . : *:. ..:*: * . *:
Mb3089|M.bovis_AF2122/97 EIAVG--------------------PTDGYVVQLRPEQVVEVALDGVQRS
Rv3062|M.tuberculosis_H37Rv EIAVG--------------------PTDGYVVQLRPEQVVEVALDGVQRS
MMAR_1623|M.marinum_M ELAVG--------------------GTDGYVVALRPEQVVEVAFDGVQAS
MUL_3413|M.ulcerans_Agy99 ELAVG--------------------GTDGYVVALRPEQVVEVAFDGVQAS
MAV_3937|M.avium_104 ELAVG--------------------GTDGYVVRVRPEQVVEVAVDGVQKS
TH_1632|M.thermoresistible__bu ELADG--------------------PTTGHVVRLRPEQVVEIAFDGVQRS
MSMEG_2277|M.smegmatis_MC2_155 ELADG--------------------PTDGYVVHLRPEQVVEIAFDGVQRS
Mflv_4321|M.gilvum_PYR-GCK DLADG-------------------DATDHYVVKVRPEQVVEIAFDGLQTS
Mvan_2025|M.vanbaalenii_PYR-1 ELADGAAPAATADHGAAPAATADHGAADGFTVTVRPEQVVEIAFDGIQTS
MAB_1033|M.abscessus_ATCC_1997 PLHRAESP----------------FDAPLSTVEAKDVQFVEPVLVAEVRY
: . : .* : *.** .. .
Mb3089|M.bovis_AF2122/97 SRYPGGLALRFARVVRYRADKDPAEADTIDAVRALY----
Rv3062|M.tuberculosis_H37Rv SRYPGGLALRFARVVRYRADKDPAEADTIDAVRALY----
MMAR_1623|M.marinum_M SRYPGGLALRFARVVRYRDDKGPADADTIDTVRALY----
MUL_3413|M.ulcerans_Agy99 SRYPGGLALRFARVVRYRDDKGPADADTIDTVRALY----
MAV_3937|M.avium_104 SRYPGGLALRFARVLRYRDDKGPAEADTIDAVRALY----
TH_1632|M.thermoresistible__bu SRYPGGMALRFARVLRYRDDKTPDEADTVDTVRRIYERGD
MSMEG_2277|M.smegmatis_MC2_155 SRYPAGMALRFVRVLRYRDDKSPAEADTVETVRRFYERD-
Mflv_4321|M.gilvum_PYR-GCK TRYPGGMALRFARVVRYRDDKAATDADTIDTVREIYERGN
Mvan_2025|M.vanbaalenii_PYR-1 SRYPGGMALRFARVLCYRDDKTAAEADTIDTVRALHERAN
MAB_1033|M.abscessus_ATCC_1997 GDRTPGGILKHSSWRGLRTDKSVRDVELDLG---------
. * *:. * ** :.: