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M. thermoresistible (build 8) TH_1364 ()

annotation: PROBABLE OXIDOREDUCTASE
coordinates: 2588771 - 2589790
length: 340

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1364-100% (340)PROBABLE OXIDOREDUCTASE
M. thermoresistible (build 8)TH_1525-3e-5841.42% (268) 2,5-diketo-D-gluconic acid reductase A

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2996-1e-10466.18% (275) oxidoreductase
M. gilvum PYR-GCKMflv_4205-1e-11671.38% (276) 2,5-didehydrogluconate reductase
M. tuberculosis H37RvRv2971-1e-10366.18% (275) oxidoreductase
M. leprae Br4923MLBr_01669-1e-10062.90% (283) putative oxidoreductase of Aldo/keto reductase family
M. abscessus ATCC 19977MAB_1528c-3e-7453.21% (265) oxidoreductase
M. marinum MMMAR_1744-1e-10162.41% (282) oxidoreductase
M. avium 104MAV_3816-2e-9866.79% (262) 2,5-diketo-D-gluconic acid reductase A
M. smegmatis MC2 155MSMEG_2407-1e-11569.61% (283) morphine 6-dehydrogenase
M. ulcerans Agy99MUL_1987-1e-10062.06% (282) oxidoreductase
M. vanbaalenii PYR-1Mvan_2161-1e-11471.74% (276) 2,5-didehydrogluconate reductase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4205|M.gilvum_PYR-GCK          MTS----AAAIPTVTLNDDNTMPVIGLGVGELSDAETEQAVTAALEAGYR
Mvan_2161|M.vanbaalenii_PYR-1       MTS----AAAIPTVILNDDNTMPVIGLGVGELSDAEAEQSVLAALEAGYR
MSMEG_2407|M.smegmatis_MC2_155      MTASHGQAAAIPTVTLNDDNTLPVVGIGVGELSDSEAERSVSAALEAGYR
TH_1364|M.thermoresistible__bu      MTSSPGEAAATPTVTLNDDRSMPVLGLGVGELSDDEAERAVAAALEAGYR
MMAR_1744|M.marinum_M               -MPGAP-SPSAPSIALNDENTMPVLGMGVAGLSDDETERAVSAALEIGCR
MUL_1987|M.ulcerans_Agy99           MMPGAP-SPSAPSIALNDENTMPVLGMGVAGLSDDETERAVSAALEIGCR
Mb2996|M.bovis_AF2122/97            MTGESG-AAAAPSITLNDEHTMPVLGLGVAELSDDETERAVSAALEIGCR
Rv2971|M.tuberculosis_H37Rv         MTGESG-AAAAPSITLNDEHTMPVLGLGVAELSDDETERAVSAALEIGCR
MLBr_01669|M.leprae_Br4923          MMPSTP-RTSIPSITLNDENTMPLLGLGVAELSEDETERAVLAALEIGCR
MAV_3816|M.avium_104                ---------------------MPVLGLGVAELSDDETERAVSAALEVGCR
MAB_1528c|M.abscessus_ATCC_199      -------------MTLNSGTTIPQLGYGVWQVPDDQARAAVSAALQVGYR
                                                         :* :* **  :.: ::. :* ***: * *

Mflv_4205|M.gilvum_PYR-GCK          LIDTAAAYGNEAAVGRAIAASGVPRDELFVTTKLATEDAGFQSSQDALRA
Mvan_2161|M.vanbaalenii_PYR-1       LIDTAAAYGNEAAVGRAIAKSGVPRGELFVTTKLATDDLGFQSSQDALRA
MSMEG_2407|M.smegmatis_MC2_155      LIDTAAAYGNEAAVGRAIAASGIPRDEIYVTTKLATPDQGFTSSQAAARA
TH_1364|M.thermoresistible__bu      LIDTAASYGNEAGVGRAIAASGLPREEIFVTTKLATTDQGFQSSQDAVRA
MMAR_1744|M.marinum_M               LIDTAAAYGNEAAVGRAIAASGIPRAELFVTTKVATADHGFTASREACKA
MUL_1987|M.ulcerans_Agy99           LIDTAAAYGNEAAVGRALAASGIPRAELFVTTKVATADHGFTASREACKA
Mb2996|M.bovis_AF2122/97            LIDTAYAYGNEAAVGRAIAASGVAREELFVTTKLATPDQGFTRSQEACRA
Rv2971|M.tuberculosis_H37Rv         LIDTAYAYGNEAAVGRAIAASGVAREELFVTTKLATPDQGFTRSQEACRA
MLBr_01669|M.leprae_Br4923          LIDTAAAYGNEAAVSRAIAASGIPRAQLFVTTKLATPDQGFTKSQDACNA
MAV_3816|M.avium_104                LIDTAAAYGNEAAVGRAIAASGIPRAELFVTTKLATSDQGFKGAMDACEA
MAB_1528c|M.abscessus_ATCC_199      SIDTAKIYDNEAGTGAAIAESGIPRGDVFLTTKLWNSDQGYDNALRAFDA
                                     ****  *.***... *:* **:.* ::::***: . * *:  :  *  *

Mflv_4205|M.gilvum_PYR-GCK          SLERLGLDYVDLYLIHWPVSQQGKHVDSWGGLMKSKEVGLTRSIGVANFH
Mvan_2161|M.vanbaalenii_PYR-1       SLERLGLDYVDLYLIHWPAGSQGTYVDSWGGLMKLKELGLTRSIGVSNFH
MSMEG_2407|M.smegmatis_MC2_155      SLERLGLDYVDLYLIHWPGGDTSKYVDSWGGLMKVKEDGIARSIGVCNFG
TH_1364|M.thermoresistible__bu      SLERLGLEYVDLYLIHWPAGEQGKYVDSWGGFLKIREDGLTRSIGVSNFD
MMAR_1744|M.marinum_M               SLDRLGLDYVDLYLIHWPAPAAGKYVDAFGGLIQARGEGFTRSIGVSNFT
MUL_1987|M.ulcerans_Agy99           SLDRLGLDYVDLYLIHWPAPAVGKYVDAFGGLIQARGEGFTRSIGVSNFT
Mb2996|M.bovis_AF2122/97            SLDRLGLDYVDLYLIHWPAPPVGKYVDAWGGMIQSRGEGHARSIGVSNFT
Rv2971|M.tuberculosis_H37Rv         SLDRLGLDYVDLYLIHWPAPPVGKYVDAWGGMIQSRGEGHARSIGVSNFT
MLBr_01669|M.leprae_Br4923          SLDRLGMDYVDLYLIHWPAPPVGQYVDAWGGMIQSRGEGHARSIGVCNFT
MAV_3816|M.avium_104                SLERLGLDYVDLYLIHWPAPALGTYVNSFGGMIQSRGNGHARSIGVSNFT
MAB_1528c|M.abscessus_ATCC_199      SLERLGTDYVDLYLIHWPVPELDEYVASFKALQRIQADGRAKAIGVSNFT
                                    **:*** :**********    . :* :: .: : :  * :::***.** 

Mflv_4205|M.gilvum_PYR-GCK          GHHLDDIISLSFFTPAVNQIELHPLLNQAELRAVNAEHGIATEAYGPLGV
Mvan_2161|M.vanbaalenii_PYR-1       AQHLDDIIGLSFFTPAVNQIELHPLLNQAELRAVNAEHGIVTEAYSPLGV
MSMEG_2407|M.smegmatis_MC2_155      AEDLETIVSLTYFTPAVNQIELHPLLNQAALREVNAGYNIVTEAYGPLGV
TH_1364|M.thermoresistible__bu      EEYLSDIIDLSFVTPAVNQIELHPLLNQADLRKVHAERNVLTQAYSPLGV
MMAR_1744|M.marinum_M               EEHVSNVIDLTFVTPAVNQVELHPLLNQDELRKANAQHNVVTQSYTPLAL
MUL_1987|M.ulcerans_Agy99           EEHVSNVIDLTFVTPAVNQVELHPLLNQDELRKANAQHNVVTQSYTPLAL
Mb2996|M.bovis_AF2122/97            AEHIENLIDLTFVTPAVNQIELHPLLNQDELRKANAQHTVVTQSYCPLAL
Rv2971|M.tuberculosis_H37Rv         AENIENLIDLTFVTPAVNQIELHPLLNQDELRKANAQHTVVTQSYCPLAL
MLBr_01669|M.leprae_Br4923          EEHLSAIIDLTFVTPAVNQIELHPLLNQDEMRKSNAQHNVITQSYTPLVL
MAV_3816|M.avium_104                EEYLTTVIDLTFVTPAVNQIELHPLLNQEALRKTNAEHNVVTQSYTPLAL
MAB_1528c|M.abscessus_ATCC_199      VDNLKRLIDETGEVPALNQIELHPRFTQPELRAFHAEYGIATEAWSPLGQ
                                     . :  ::. :  .**:**:**** :.*  :*  :*   : *::: **  

Mflv_4205|M.gilvum_PYR-GCK          GNLLSHSAVNAIAEAHGRTPAQVLIRWSLQLGNIVIPRSSSPERIRSNID
Mvan_2161|M.vanbaalenii_PYR-1       GSLLSNPAVTAIADAQDRTPAQVLIRWSLQLGNVVISRSSSPERIKSNLD
MSMEG_2407|M.smegmatis_MC2_155      GRLLDHPAVTAIAEAHGRTAAQVLLRWSIQLGNVVISRSANPERIASNLD
TH_1364|M.thermoresistible__bu      GNLLADPTIGAVAQAHGKSPAQVLLRWNLQLGNAVVVRSSNPDRMRENLA
MMAR_1744|M.marinum_M               GQLADNPTVTSIAGEYGKTPTQVLLRWNLQLGNAVIFGSSNAEHIATNLD
MUL_1987|M.ulcerans_Agy99           GQLADNPTVTSIAGEYGKTPTQVLLRWNLQLGNAVIFGSSNAEHIVTNLD
Mb2996|M.bovis_AF2122/97            GRLLDNPTVTSIASEYVKTPAQVLLRWNLQLGNAVVVRSARPERIASNFD
Rv2971|M.tuberculosis_H37Rv         GRLLDNPTVTSIASEYVKTPAQVLLRWNLQLGNAVVVRSARPERIASNFD
MLBr_01669|M.leprae_Br4923          GRLMDNSTLTAIAAEYGKTPAQVLLRWNLQLGNAVVFRSAKAEHIASNFD
MAV_3816|M.avium_104                GKLNDHPTVNSVAAEYGKTASQVLLRWNLQLGNAVIFRSANAEHIASDFD
MAB_1528c|M.abscessus_ATCC_199      GTILEDATIGAIAQAHDVSAAQVILRWHLQLGNVVIPKSVTPARIAANFD
                                    * :  ..:: ::*     :.:**::** :**** *:  *  . ::  :: 

Mflv_4205|M.gilvum_PYR-GCK          VFGFELSEEQMSTLNGLDDG-TRFRPDPETYSGS----------------
Mvan_2161|M.vanbaalenii_PYR-1       VFDFELTADQMAALDGLDEG-TRFRPDPETYTGS----------------
MSMEG_2407|M.smegmatis_MC2_155      VFGFELTADEMETLNGLDDG-TRFRPDPATYTGS----------------
TH_1364|M.thermoresistible__bu      VFDFELTDDEMNTINGMDNG-TRYRPDPXXGEGAAAEHQSADSAAGTAVP
MMAR_1744|M.marinum_M               VFEFELASQHMDAINGLNDG-TRLREDPMTFAGV----------------
MUL_1987|M.ulcerans_Agy99           VFEFELASQHMDAINGLNDG-TRLREDPMTFAGV----------------
Mb2996|M.bovis_AF2122/97            VFDFELAAEHMDALGGLNDG-TRVREDPLTYAGT----------------
Rv2971|M.tuberculosis_H37Rv         VFDFELAAEHMDALGGLNDG-TRVREDPLTYAGT----------------
MLBr_01669|M.leprae_Br4923          VFDFELAVNHMDAMNELHDG-TRLRPDPETYAGS----------------
MAV_3816|M.avium_104                VFDFELAAEHMDAINALNDG-TRLRPDPDTYEGS----------------
MAB_1528c|M.abscessus_ATCC_199      VFGFELSTDEVERITALDASDGRIGPDPTTFNLH----------------
                                    ** ***: :.:  :  :. .  *   **                      

Mflv_4205|M.gilvum_PYR-GCK          ----------------------------------------
Mvan_2161|M.vanbaalenii_PYR-1       ----------------------------------------
MSMEG_2407|M.smegmatis_MC2_155      ----------------------------------------
TH_1364|M.thermoresistible__bu      GHPVRRGGCARRQRRPGTAADHLLHRRSDGLSVEQVDHQR
MMAR_1744|M.marinum_M               ----------------------------------------
MUL_1987|M.ulcerans_Agy99           ----------------------------------------
Mb2996|M.bovis_AF2122/97            ----------------------------------------
Rv2971|M.tuberculosis_H37Rv         ----------------------------------------
MLBr_01669|M.leprae_Br4923          ----------------------------------------
MAV_3816|M.avium_104                ----------------------------------------
MAB_1528c|M.abscessus_ATCC_199      ----------------------------------------