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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_1339 | aceE | - | 100% (930) | Probable pyruvate dehydrogenase E1 component aceE (PYRUVATE DECARBOXYLASE) (PYRUVATE DEHYDROGENASE) (PYRUVIC DEHYDROGENASE) |
M. thermoresistible (build 8) | TH_2532 | - | 2e-43 | 25.18% (822) | PUTATIVE pyruvate dehydrogenase alpha subunit |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2265 | aceE | 0.0 | 86.41% (898) | pyruvate dehydrogenase subunit E1 |
M. gilvum PYR-GCK | Mflv_2781 | aceE | 0.0 | 86.54% (929) | pyruvate dehydrogenase subunit E1 |
M. tuberculosis H37Rv | Rv2241 | aceE | 0.0 | 86.53% (898) | pyruvate dehydrogenase subunit E1 |
M. leprae Br4923 | MLBr_01651 | aceE | 0.0 | 82.28% (931) | pyruvate dehydrogenase subunit E1 |
M. abscessus ATCC 19977 | MAB_1884c | aceE | 0.0 | 83.98% (905) | pyruvate dehydrogenase subunit E1 |
M. marinum M | MMAR_3334 | aceE | 0.0 | 84.07% (929) | pyruvate dehydrogenase E1 component AceE |
M. avium 104 | MAV_2196 | aceE | 0.0 | 86.54% (929) | pyruvate dehydrogenase subunit E1 |
M. smegmatis MC2 155 | MSMEG_4323 | aceE | 0.0 | 85.68% (929) | pyruvate dehydrogenase subunit E1 |
M. ulcerans Agy99 | MUL_1308 | aceE | 0.0 | 83.85% (929) | pyruvate dehydrogenase subunit E1 |
M. vanbaalenii PYR-1 | Mvan_3752 | aceE | 0.0 | 87.23% (924) | pyruvate dehydrogenase subunit E1 |
CLUSTAL 2.0.9 multiple sequence alignment TH_1339|M.thermoresistible__bu LTTEFVRQDLAQNSKSTTGHGRVRVIRDGVAAYLPDIDPEETAEWLESFD MAB_1884c|M.abscessus_ATCC_199 ------------------------MIREGVASYLPDIDPDETGEWLESFD MSMEG_4323|M.smegmatis_MC2_155 MTTEFVRQDLAQNSSTAAEPDRVRVIREGVASYLPDIDTEETAEWLESFD Mflv_2781|M.gilvum_PYR-GCK MTTEFVRQDLAQNSSSTGEPDRVRVIREGVASYLPDIDPEETGEWLESFD Mvan_3752|M.vanbaalenii_PYR-1 -----MRQDLAQNSGSTAEPDRVRVIREGVASYLPDIDPEETGEWLESFD Mb2265|M.bovis_AF2122/97 -----------------------------MASYLPDIDPEETSEWLESFD Rv2241|M.tuberculosis_H37Rv -----------------------------MASYLPDIDPEETSEWLESFD MLBr_01651|M.leprae_Br4923 MTIEFARPDLAKNPSSTNESNSVRVIREGVASYLPDIDPEETAEWLESFD MAV_2196|M.avium_104 MTTEFVRHDLATNPTGPAEPDRVRVIREGVASYLPDIDPEETSEWLESFD MMAR_3334|M.marinum_M MTTEFVRHDLAKTSSSASEPDRVRVIREGVASYLPDIDPEETSEWLESFD MUL_1308|M.ulcerans_Agy99 MTTEFVRHDLAKTSSSASEPDRVRVIREGVASYLPDIDPEETSEWLESFD :*:******.:**.******* TH_1339|M.thermoresistible__bu QLVERSGPARARYLMLRMLERAREQRVAIPALTSTDYVNTIPTENEPWFP MAB_1884c|M.abscessus_ATCC_199 GLLARSGPARARYLMLRLLERANAGRVAIPALTSTDYVNTIPTENEPWFP MSMEG_4323|M.smegmatis_MC2_155 ELLERSGPARARYLMLRLLERAGEQRVAIPALTSTDYVNTIPTELEPWFP Mflv_2781|M.gilvum_PYR-GCK DLLERSGPARARYLMLRLLERAGEQRVAIPALTSTDYVNTIPTELEPWFP Mvan_3752|M.vanbaalenii_PYR-1 DLLERSGPARARYLMLRLLERSREKRVAIPALTSTDYVNTIPTELEPWFP Mb2265|M.bovis_AF2122/97 TLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVNTIPTELEPWFP Rv2241|M.tuberculosis_H37Rv TLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVNTIPTELEPWFP MLBr_01651|M.leprae_Br4923 ELLKHSGPSRARYLILRLLERAGEQRVTIPALTWTDYVNTIPTELEPWFP MAV_2196|M.avium_104 ELLERSGPSRARYLMLRLLERAGEQRVAIPSLTSTDYVNTIPTELEPWFP MMAR_3334|M.marinum_M ALLEHSGPARARYLMLRLLERAGEQRVAIPSLTSTDYVNTIPTELEPWFP MUL_1308|M.ulcerans_Agy99 ALLEHSGPARARYLMLRLLERAGEQRVAIPSLTSTDYVNTIPTELEPWFP *: :.**:*****:**:***: **:**:** ********** ***** TH_1339|M.thermoresistible__bu GDEDTERRFRLWIRWNAAIMVHRAQRPGVGVGGHISTYASSATLYEVGFN MAB_1884c|M.abscessus_ATCC_199 GDEDTERRFRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN MSMEG_4323|M.smegmatis_MC2_155 GDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSATLYEVGFN Mflv_2781|M.gilvum_PYR-GCK GDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN Mvan_3752|M.vanbaalenii_PYR-1 GDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN Mb2265|M.bovis_AF2122/97 GDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN Rv2241|M.tuberculosis_H37Rv GDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN MLBr_01651|M.leprae_Br4923 GDEDIERRYRTWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN MAV_2196|M.avium_104 GDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN MMAR_3334|M.marinum_M GDEDVERRYRTWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN MUL_1308|M.ulcerans_Agy99 GDEDVERRYRTWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN **** ***:* *******************************:******* TH_1339|M.thermoresistible__bu HFFRGKAHPGGGDQVFIQGHASPGIYARAFLEGRLTADQLDGFRQEHSHP MAB_1884c|M.abscessus_ATCC_199 HFFRGNAHPGGGDQIFIQGHASPGIYARAFLEGRLTTDQLDGFRQEKSHP MSMEG_4323|M.smegmatis_MC2_155 HFFRGKSHPGGGDHVFIQGHASPGIYARAFLEGRLTTDQLDGFRQEHSHS Mflv_2781|M.gilvum_PYR-GCK HFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTTDQLDGFRQEHSHA Mvan_3752|M.vanbaalenii_PYR-1 HFFRGKSHPGGGDQIFIQGHASPGIYARAYLEGRLSADQLDGFRQEHSHP Mb2265|M.bovis_AF2122/97 HFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHV Rv2241|M.tuberculosis_H37Rv HFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHV MLBr_01651|M.leprae_Br4923 HFFRGKSHPSGGDQVFIQGHASPGIYARAFLEGRLSADQLDGFRQEHSHP MAV_2196|M.avium_104 HFFRGKSHPGGGDQIFIQGHASPGIYARAFLEGRLTADQLDGFRQEHSHA MMAR_3334|M.marinum_M HFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLSADQLDGFRQEHSHP MUL_1308|M.ulcerans_Agy99 HFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLSADQLDGFRQEHSHP *****::**.***::**************:*****:::********:** TH_1339|M.thermoresistible__bu GGGLPSYPHPRLMPDFWEFPTVSMGLGPINAIFQARFNRYLHNRGIKDTS MAB_1884c|M.abscessus_ATCC_199 GGGLPSYPHPRLMPDFWQFPTVSMGLGPMNAIMQARFNHYLRDRGIKDTS MSMEG_4323|M.smegmatis_MC2_155 GGGLPSYPHPRLMPDFWEFPTVSMGLGPMNAIYQARFNHYLHDRGIKDTS Mflv_2781|M.gilvum_PYR-GCK GGGLPSYPHPRLMPDFWEFPTVSMGLGPMNAIYQARFNHYLHDRDIKDTS Mvan_3752|M.vanbaalenii_PYR-1 GGGLPSYPHPRLMPDFWEFPTVSMGLGPMNAIYQARFNHYLHDRGIKDTS Mb2265|M.bovis_AF2122/97 GGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTS Rv2241|M.tuberculosis_H37Rv GGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTS MLBr_01651|M.leprae_Br4923 GGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNRYLHDRGIKDTS MAV_2196|M.avium_104 GGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTS MMAR_3334|M.marinum_M GGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTS MUL_1308|M.ulcerans_Agy99 GGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTS *****************:**********:*** *****:**::*.***** TH_1339|M.thermoresistible__bu GQHVWCFLGDGEMDEPESRGAAHVAALEGLDNLTFVVNCNLQRLDGPVRG MAB_1884c|M.abscessus_ATCC_199 DQRVWAFLGDGEMDEPESRGLAHIAATEGLDNLTFVVNCNLQRLDGPVRG MSMEG_4323|M.smegmatis_MC2_155 DQHVWAFLGDGEMDEPESRGLIQVAANEALDNLTFVINCNLQRLDGPVRG Mflv_2781|M.gilvum_PYR-GCK KQHVWAFLGDGEMDEPESRGLIQVAANEGLDNLTFVVNCNLQRLDGPVRG Mvan_3752|M.vanbaalenii_PYR-1 KQHVWAFLGDGEMDEPESRGLIQVAANEALDNLTFVVNCNLQRLDGPVRG Mb2265|M.bovis_AF2122/97 DQHVWCFLGDGEMDEPESRGLAHVGALEGLDNLTFVINCNLQRLDGPVRG Rv2241|M.tuberculosis_H37Rv DQHVWCFLGDGEMDEPESRGLAHVGALEGLDNLTFVINCNLQRLDGPVRG MLBr_01651|M.leprae_Br4923 DQHVWCFLGDGEMDEPESRGLAHVASLEDLDNLIFVINCNLQRLDGPVRG MAV_2196|M.avium_104 DQHVWCFLGDGEMDEPESRGLIQVAANEALDNLTFVINCNLQRLDGPVRG MMAR_3334|M.marinum_M DQHVWCFLGDGEMDEPESRGLAHMGALEGLDNLTFVINCNLQRLDGPVRG MUL_1308|M.ulcerans_Agy99 DQHVWCFLGDGEMDEPESRGLAHMGALEGLDNLTFVINCNLQRLDGPVRG *:**.************** ::.: * **** **:************* TH_1339|M.thermoresistible__bu NGKIIQELEAFFRGAGWNVIKVVWGREWDALLHADKDGALVNLMNTTPDG MAB_1884c|M.abscessus_ATCC_199 NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTADG MSMEG_4323|M.smegmatis_MC2_155 NGKIIQELESFFRGAGWNVIKVVWGREWDVLLHADRDGALVNLMNSTPDG Mflv_2781|M.gilvum_PYR-GCK NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDG Mvan_3752|M.vanbaalenii_PYR-1 NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDG Mb2265|M.bovis_AF2122/97 NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDRALVNLMNTTPDG Rv2241|M.tuberculosis_H37Rv NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDG MLBr_01651|M.leprae_Br4923 NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVDLMNATPDG MAV_2196|M.avium_104 NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDG MMAR_3334|M.marinum_M NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNSTPDG MUL_1308|M.ulcerans_Agy99 NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNSTPDG *********:*******************.*****:* ***:***:*.** TH_1339|M.thermoresistible__bu DYQTYKANDGAYVREHFFGRDPRTKALVQNMTDQEIWNLKRGGHDYRKVY MAB_1884c|M.abscessus_ATCC_199 DYQTYKANDGAYVREHFFGRDPRTKELVKDLTDAQVWNLKRGGHDYRKVY MSMEG_4323|M.smegmatis_MC2_155 DYQTYKANDGAYVRDHFFGRDPRTKALVADMSDQEIWNLKRGGHDYRKVY Mflv_2781|M.gilvum_PYR-GCK DYQTYKANDGSYVRDHFFGRDPRTKALVEPMTDAEIWNLKRGGHDYRKVY Mvan_3752|M.vanbaalenii_PYR-1 DYQTYKANDGAYVRDHFFGRDPRTKALVENMTDREIWNLKRGGHDYRKVY Mb2265|M.bovis_AF2122/97 DYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNLKRGGHDYRKVY Rv2241|M.tuberculosis_H37Rv DYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNLKRGGHDYRKVY MLBr_01651|M.leprae_Br4923 DYQTYKANDGRFVRDHFFGRDPRTKALVEHMSDQEIWNLKRGGHDYRKVY MAV_2196|M.avium_104 DYQTYKANDGAYVRDHFFGRDPRTKALVENMTDAEIWNLKRGGHDYRKVY MMAR_3334|M.marinum_M DYQTYKANDGAYVRDHFFGRDPRTKALVANMSDQEIWNLKRGGHDYRKVY MUL_1308|M.ulcerans_Agy99 DYQTYKANDGAYVRDHFFGRDPRTKALVANMSDQEIWNLKRGGHDYRKVY ********** :**:********** ** ::* ::************** TH_1339|M.thermoresistible__bu AAYRAAVEHKGQPTVILAKTIKGYSLGANFQGRNATHQMKKLALDDLKHF MAB_1884c|M.abscessus_ATCC_199 AAYRAATEHKGQPTVILAKTIKGYTLGKHFEGRNATHQMKKLTLDDLKDF MSMEG_4323|M.smegmatis_MC2_155 AAYRAAMEHKGQPTVILAKTIKGYTLGQHFEGRNATHQMKKLALEDLKNF Mflv_2781|M.gilvum_PYR-GCK AAYHAAMEHKGQPTVILAKTIKGYTLGKHFEGRNATHQMKKLALQDLKDF Mvan_3752|M.vanbaalenii_PYR-1 AAYHAALEHKGQPTVILAKTIKGYTLGKHFEGRNATHQMKKLALQDLKDF Mb2265|M.bovis_AF2122/97 AAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKEF Rv2241|M.tuberculosis_H37Rv AAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKEF MLBr_01651|M.leprae_Br4923 ASYRAAVDHKGQPTVILAKTIKGYALGKHFESRNATHQMKKLTLEDLKEF MAV_2196|M.avium_104 AAYRAAVDHKGQPTVILAKTIKGYSLGAHFQGRNATHQMKKLALEDLKHF MMAR_3334|M.marinum_M AAYRAAVDHKGQPTVILAKTIKGYSLGAHFQGRNATHQMKKLALADLKRF MUL_1308|M.ulcerans_Agy99 AAYRAAVDHKGQPTVILAKTIKGYSLGAHFQGRNATHQMKKLALADLKRF *:*:** :****************:** :*:.**********:* *** * TH_1339|M.thermoresistible__bu RDAMRIPISDEQLEENPYLPPYYHPGPEAPEIRYMLERRRALGGFVPERR MAB_1884c|M.abscessus_ATCC_199 RDKQRIPISDAQLEENPYLPPYYHPGPEAPEIRYMLDRRRALGGFVPSRR MSMEG_4323|M.smegmatis_MC2_155 RDVTRVPVSDAQLEEDPYLPPYYHPGPEAPEIRYLLERRRALGGFVPSRR Mflv_2781|M.gilvum_PYR-GCK RDVQRIPVSDSQLEENPYLPPYYHPGPEAPEIRYMLDRRRALGGFLPERR Mvan_3752|M.vanbaalenii_PYR-1 RDAQRIPVSDEQLEADPYLPPYYHPGPEAPEIRYMLDRRRALGGFLPERR Mb2265|M.bovis_AF2122/97 RDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERR Rv2241|M.tuberculosis_H37Rv RDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERR MLBr_01651|M.leprae_Br4923 RDTQRIPISDTELEENPYLPPYYHPGPDSPEIRYLLDRRRALGGFLPERR MAV_2196|M.avium_104 RDAMRIPISDAQLDENPYLPPYYHPGSDAPEIRYMLDRRRTLGGFLPERR MMAR_3334|M.marinum_M RDSMRIPVSDAQLDEDPYLPPYYHPGSDAPEIRYMLDRRRTLGGFLPERP MUL_1308|M.ulcerans_Agy99 RDSMRIPVSDAQLDEDPYLPPYYHPGSDAPEIRYMLDRRRTLGGFLPERP ** *:*:** :*: :********** ::*****:*:***:****:*.* TH_1339|M.thermoresistible__bu TTSKALRIPGSDIFRSVRKGSGNQEVATTMATVRTFREVLRDKELGWRIV MAB_1884c|M.abscessus_ATCC_199 TTSRPLTLPGSETYASIKKGSGKQEVATTMALVRTFKELLRDKNIGNRIV MSMEG_4323|M.smegmatis_MC2_155 TKSKPLALPGSDTYKALKKGSGSQAVATTMATVRTFKELLRDKNIGPRIV Mflv_2781|M.gilvum_PYR-GCK TKTKALTLPGRDTYKALKKGSGKQEVATTMATVRTFKELLRDKNIGWRIV Mvan_3752|M.vanbaalenii_PYR-1 TKSRALTLPGRDVYKALKKGSGKQEVATTMATVRTFKELLRDKNIGSRIV Mb2265|M.bovis_AF2122/97 TKSKALTLPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIV Rv2241|M.tuberculosis_H37Rv TKSKALTLPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIV MLBr_01651|M.leprae_Br4923 TKSGALTLPGRDTYAALKTGSGQQEVATTMAIVRTFKEVLRHKEVGPRIV MAV_2196|M.avium_104 TKAKALRLPGRDIYAALKKGSGTQEVATTMATVRTFKEVLRDKEIGPRIV MMAR_3334|M.marinum_M TKAKTLTLPGPDAYKVLKKGSGQQEVATTMALVRTFKELLRDKNIGNRIV MUL_1308|M.ulcerans_Agy99 TKAKTLTLPGPDAYKVLKKGSGQQEVATTMALVRTFKELLRDKNIGNRIV *.: .* :** : : ::.*** * ****** ****:*:**.*::* *** TH_1339|M.thermoresistible__bu PIIPDEARTFGMDSWFPSLKIYNPNGQLYTSVDADLMLAYKESEAGQILH MAB_1884c|M.abscessus_ATCC_199 PIIPDEARTFGMDSWFPSLKIYNRNGQLYTSVDAELMLAYKESAQGQILH MSMEG_4323|M.smegmatis_MC2_155 PIIPDEARTFGMDSWFPSLKIYNRNGQLYTSVDSELMLAYKESEVGQILH Mflv_2781|M.gilvum_PYR-GCK PIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDAELMLAYKESEVGQILH Mvan_3752|M.vanbaalenii_PYR-1 PIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDAELMLAYKESEIGQILH Mb2265|M.bovis_AF2122/97 PIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDADLMLAYKESEVGQILH Rv2241|M.tuberculosis_H37Rv PIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDADLMLAYKESEVGQILH MLBr_01651|M.leprae_Br4923 PIIPDEARTFGMDSWFPSLKIYNHNGQLYTAVDAQLMLAYKESEVGQILH MAV_2196|M.avium_104 PIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDAELMLAYKESEVGQILH MMAR_3334|M.marinum_M PIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDAELMLAYKESHVGQILH MUL_1308|M.ulcerans_Agy99 PIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDAELMLAYKESHVGQILH *********************** ******:**::******** ***** TH_1339|M.thermoresistible__bu EGINEAGSSASFIAAGTSYATHNEPMIPIYIFYSMFGFQRTGDNLWAAGD MAB_1884c|M.abscessus_ATCC_199 EGINEAGSTASFTAVGTAYSTHDEPMIPLYIFYSMFGFQRTGDGLWAAAD MSMEG_4323|M.smegmatis_MC2_155 EGINEAGSTSSFTAVGTSYSTHDEPMIPIYIFYSMFGFQRTGDGLWAAAD Mflv_2781|M.gilvum_PYR-GCK EGINEAGSTASFTAVGTSYATHNEPMIPIYIFYSMFGFQRTGDGLWAAAD Mvan_3752|M.vanbaalenii_PYR-1 EGINEAGSTASFTAVGTSYATHNEPMIPIYIFYSMFGFQRTGDGLWAAAD Mb2265|M.bovis_AF2122/97 EGINEAGSVGSFIAAGTSYATHNEPMIPIYIFYSMFGFQRTGDSFWAAAD Rv2241|M.tuberculosis_H37Rv EGINEAGSVGSFIAAGTSYATHNEPMIPIYIFYSMFGFQRTGDSFWAAAD MLBr_01651|M.leprae_Br4923 EGIDEAGSVGSFIAAGTSYSTHNEPMIPIYIFYSMFGFQRTGDGLWAAAD MAV_2196|M.avium_104 EGINEAGSVGSFIAAGTSYATHNEPMIPIYIFYSMFGFQRTGDGLWAAAD MMAR_3334|M.marinum_M EGINEAGSVGSFTAAGTSYATHNEPMIPIYIFYSMFGFQRTGDSFWAAAD MUL_1308|M.ulcerans_Agy99 EGINEAGSVGSFTAAGTSYATHNEPMIPIYIFYSMFGFQRTGDSFWAAAD ***:**** .** *.**:*:**:*****:**************.:***.* TH_1339|M.thermoresistible__bu QMARGFLLGATAGRTTLVGEGLQHADGHSLLLASTNPAVVAYDPAFAYEI MAB_1884c|M.abscessus_ATCC_199 QMARGFVLGATAGRTTLTGEGLQHADGHSLLLASTNPAVVAYDPAFAYEI MSMEG_4323|M.smegmatis_MC2_155 QMARGFVLGATAGRTTLTGEGLQHADGHSLLLASTNPAAVTYDPAFAYEI Mflv_2781|M.gilvum_PYR-GCK QMARGFVLGATAGRTTLVGEGLQHADGHSLLLAATNPAVVSYDPAFAFEI Mvan_3752|M.vanbaalenii_PYR-1 QMARGFVLGATAGRTTLVGEGLQHADGHSLLLASTNPAVVAYDPAFAYEI Mb2265|M.bovis_AF2122/97 QMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVAYDPAFAYEI Rv2241|M.tuberculosis_H37Rv QMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVAYDPAFAYEI MLBr_01651|M.leprae_Br4923 QMARGFLLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVTYDPAFAYEI MAV_2196|M.avium_104 QMTRGFLLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVAYDPAFAYEI MMAR_3334|M.marinum_M QMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVSYDPAFAYEL MUL_1308|M.ulcerans_Agy99 QMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVSYDPAFAYEL **:***:**********.***************:****.*:******:*: TH_1339|M.thermoresistible__bu AHIVESGLHRMYGENPENVFFYLTIYNEPYRQPAEPEDLDVEGLLRGIYR MAB_1884c|M.abscessus_ATCC_199 AHIVEHGLQRMYGENSENVYFYITLYNEPYVQPAEPENVDTEGILRGIYK MSMEG_4323|M.smegmatis_MC2_155 AHIIESGLQRMYGEDPENVFFYLTIYNEPYQQPAEPENLDVEALLKGLYL Mflv_2781|M.gilvum_PYR-GCK AYIIESGLQRMYGDNPENVYFYMTIYNEPYVQPAEPEGIDVEGLLRGMYR Mvan_3752|M.vanbaalenii_PYR-1 AYIIESGLHRMYGENPENVYFYMTIYNEPYVQPAEPDGLDVEGLLRGMYR Mb2265|M.bovis_AF2122/97 AYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIYR Rv2241|M.tuberculosis_H37Rv AYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIYR MLBr_01651|M.leprae_Br4923 AYIVESGLTRMFGEDPENVFFYITVYNEPYPQPPEPENFDPDGVLRGMYR MAV_2196|M.avium_104 AYIVESGLARMFGENPEDVYFYITVYNEPYVQPPEPENFDPEGLLRGLYR MMAR_3334|M.marinum_M AYIIENGLSRMFGENPENIYFYITVYNEPYVQPAEPENFDPEGVLRGMYR MUL_1308|M.ulcerans_Agy99 AYIIENGLSRMFGENPENIYFYITVYNEPYVQPAEPENFDPEGVLRGMYR *:*:* ** ** *::.*:::**:*:***** **.**:..* :.:*:*:* TH_1339|M.thermoresistible__bu YRRAPQKRTHTAQILASGVAMPEALRAADLLAEDWDVAADVWSVTSWGEL MAB_1884c|M.abscessus_ATCC_199 FRAAPEARTHRANILASGVSVPDALRAADLLAEQWDVAADVWSVTSWGEL MSMEG_4323|M.smegmatis_MC2_155 YRPAPEKRAKSAQILASGVAMPEALRAADLLASDWDVAADVWSVTSWGEL Mflv_2781|M.gilvum_PYR-GCK YQAAPQKKSNSAQILVSGVSMPSALKAAEMLAEEWDVSADVWSVTSWGEL Mvan_3752|M.vanbaalenii_PYR-1 YQAAPEKRTNAAQILVSGVGMPSALKAAELLAQEWDVAADVWSVTSWGEL Mb2265|M.bovis_AF2122/97 YHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGEL Rv2241|M.tuberculosis_H37Rv YHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGEL MLBr_01651|M.leprae_Br4923 YYTAKEQRSNKAHILASGVSMPAALTAAEMLSTQWDVAADVWSVTSWGEL MAV_2196|M.avium_104 YHVATEQRANKAQILASGVAMPSALSAAKMLADEWDVAADVWSVTSWGEL MMAR_3334|M.marinum_M YRAATKQCAHKAQLLASGVSMPDALKAAQMLADEWDVATDVWSVTSWSEL MUL_1308|M.ulcerans_Agy99 YRAATKQCAHKAQLLASGVSMPDALKAAQMLADEWDVATDVWSVTSWSEL : * : :: *::*.***.:* ** **.:*: :***::********.** TH_1339|M.thermoresistible__bu NRDGVTIEKQRLRHPDQPADTPYVTRALADAS----GPVVAVSDWMRAVP MAB_1884c|M.abscessus_ATCC_199 NRDGLAIDHQALRHPDRPKGVPYVTKALEGAQ----GPKVAVSDWMHAVP MSMEG_4323|M.smegmatis_MC2_155 NREGVAIEKHRLRHPDEPAGTPHVTSALADAA----GPVIAVSDWMRAVP Mflv_2781|M.gilvum_PYR-GCK NREGVAIEKERLRHPDREVATPYVTEALAGAE----GPVVAVSDWMRAVP Mvan_3752|M.vanbaalenii_PYR-1 NRDGVAIEREKLRHPELPAATPYVTKMLAEAA----GPVVAVSDWMRAVP Mb2265|M.bovis_AF2122/97 NRDGVAIETEKLRHPDRPAGVPYVTRALENAR----GPVIAVSDWMRAVP Rv2241|M.tuberculosis_H37Rv NRDGVAIETEKLRHPDRPAGVPYVTRALENAR----GPVIAVSDWMRAVP MLBr_01651|M.leprae_Br4923 NRDGMSIETARLRYPDQPTSVPYVTQVLSEARSDNAGPVIAVSDWMRAVP MAV_2196|M.avium_104 NRDGVAIDRARLRHPDRPAGVPYVTQALSDAS----GPVVAVSDWMRAVP MMAR_3334|M.marinum_M NRDGVSVERHRLRHPGEPAGVAYVTTALEGTS----GPVVAVSDWMRAVP MUL_1308|M.ulcerans_Agy99 NRDGVSVERHRLRHPGEPAGVAYVTTALEGTS----GPVVAVSDWMRAVP **:*:::: **:* ..:** * : ** :******:*** TH_1339|M.thermoresistible__bu EQIRAWVPGTYITLGTDGFGFSDTRPAARRYFNTDAESVAVAVLEGLARD MAB_1884c|M.abscessus_ATCC_199 EQIRPWVPGMYRTLGADGFGISDTRPAARRFFNTDAESVVVAVLEALADE MSMEG_4323|M.smegmatis_MC2_155 EQIRPWVPGTYVTLGTDGFGFSDTRPAARRYFNTDAESVVVAVLQGLARD Mflv_2781|M.gilvum_PYR-GCK EQIRPWVPGTYVTLGTDGFGFSDTRPAARRYYNTDAESIVVAVLEGLARD Mvan_3752|M.vanbaalenii_PYR-1 EQIRPWVPGTYITLGTDGFGFSDTRPAARRYYNTDAESVVVAVLEGLARD Mb2265|M.bovis_AF2122/97 EQIRPWVPGTYLTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALAGD Rv2241|M.tuberculosis_H37Rv EQIRPWVPGTYLTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALAGD MLBr_01651|M.leprae_Br4923 EQIRPWVPGTYVTLGTDGFGFSDTRTATRRYFNTDAESQVVAVLEALARD MAV_2196|M.avium_104 EQIRPWVPGTYVTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALARD MMAR_3334|M.marinum_M EQIRPWVPGTYVTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALARD MUL_1308|M.ulcerans_Agy99 EQIRPWVPGTYVTLGTDGFGFSNTRPAARRYFNTDAESQVVAVLEALARD ****.**** * ***:****:*:**.*:**::****** .****:.** : TH_1339|M.thermoresistible__bu GNLDRSVAVEAARRYRIDDVMAAPEQTSDPGVA--- MAB_1884c|M.abscessus_ATCC_199 GSVDRQVAVTAAAQYKIDDVSAADVSYKDTGSA--- MSMEG_4323|M.smegmatis_MC2_155 GEIDASVAAQAAEQYRIDDVSAAGVSYADTGSA--- Mflv_2781|M.gilvum_PYR-GCK GNIDISAAVDAARRYEIDDVMAAPEQTSDPGVA--- Mvan_3752|M.vanbaalenii_PYR-1 GNIDISVAVEAAKKYEIDDVMAAPEQTSDPGVA--- Mb2265|M.bovis_AF2122/97 GEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPGA-- Rv2241|M.tuberculosis_H37Rv GEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPGA-- MLBr_01651|M.leprae_Br4923 GEIDPSVPVAATRQYQIDDVQAAPEQTSDPGPGVQN MAV_2196|M.avium_104 GEIDPSVPVAAARQYRIDDVLAAPEQTSDPGVA--- MMAR_3334|M.marinum_M GEIDESVAVTAARQYRIDDVQAAPKQTSDSGVA--- MUL_1308|M.ulcerans_Agy99 GEIDESMAVTAARQYRIDDVQAAPKQTSDSGVA--- *.:* . .. *: :*.**** ** . *.* .