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VRQDLAQNSGSTAEPDRVRVIREGVASYLPDIDPEETGEWLESFDDLLERSGPARARYLMLRLLERSREK RVAIPALTSTDYVNTIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALY EVGFNHFFRGKSHPGGGDQIFIQGHASPGIYARAYLEGRLSADQLDGFRQEHSHPGGGLPSYPHPRLMPD FWEFPTVSMGLGPMNAIYQARFNHYLHDRGIKDTSKQHVWAFLGDGEMDEPESRGLIQVAANEALDNLTF VVNCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDGDYQTY KANDGAYVRDHFFGRDPRTKALVENMTDREIWNLKRGGHDYRKVYAAYHAALEHKGQPTVILAKTIKGYT LGKHFEGRNATHQMKKLALQDLKDFRDAQRIPVSDEQLEADPYLPPYYHPGPEAPEIRYMLDRRRALGGF LPERRTKSRALTLPGRDVYKALKKGSGKQEVATTMATVRTFKELLRDKNIGSRIVPIIPDEARTFGMDSW FPSLKIYNRNGQLYTAVDAELMLAYKESEIGQILHEGINEAGSTASFTAVGTSYATHNEPMIPIYIFYSM FGFQRTGDGLWAAADQMARGFVLGATAGRTTLVGEGLQHADGHSLLLASTNPAVVAYDPAFAYEIAYIIE SGLHRMYGENPENVYFYMTIYNEPYVQPAEPDGLDVEGLLRGMYRYQAAPEKRTNAAQILVSGVGMPSAL KAAELLAQEWDVAADVWSVTSWGELNRDGVAIEREKLRHPELPAATPYVTKMLAEAAGPVVAVSDWMRAV PEQIRPWVPGTYITLGTDGFGFSDTRPAARRYYNTDAESVVVAVLEGLARDGNIDISVAVEAAKKYEIDD VMAAPEQTSDPGVA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3752 | aceE | - | 100% (924) | pyruvate dehydrogenase subunit E1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2265 | aceE | 0.0 | 87.86% (898) | pyruvate dehydrogenase subunit E1 |
| M. gilvum PYR-GCK | Mflv_2781 | aceE | 0.0 | 93.83% (924) | pyruvate dehydrogenase subunit E1 |
| M. tuberculosis H37Rv | Rv2241 | aceE | 0.0 | 87.97% (898) | pyruvate dehydrogenase subunit E1 |
| M. leprae Br4923 | MLBr_01651 | aceE | 0.0 | 84.00% (925) | pyruvate dehydrogenase subunit E1 |
| M. abscessus ATCC 19977 | MAB_1884c | aceE | 0.0 | 85.30% (905) | pyruvate dehydrogenase subunit E1 |
| M. marinum M | MMAR_3334 | aceE | 0.0 | 86.69% (924) | pyruvate dehydrogenase E1 component AceE |
| M. avium 104 | MAV_2196 | aceE | 0.0 | 88.74% (924) | pyruvate dehydrogenase subunit E1 |
| M. smegmatis MC2 155 | MSMEG_4323 | aceE | 0.0 | 88.20% (924) | pyruvate dehydrogenase subunit E1 |
| M. thermoresistible (build 8) | TH_1339 | aceE | 0.0 | 87.23% (924) | Probable pyruvate dehydrogenase E1 component aceE (PYRUVATE |
| M. ulcerans Agy99 | MUL_1308 | aceE | 0.0 | 86.47% (924) | pyruvate dehydrogenase subunit E1 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3752|M.vanbaalenii_PYR-1 -----MRQDLAQNSGSTAEPDRVRVIREGVASYLPDIDPEETGEWLESFD
Mflv_2781|M.gilvum_PYR-GCK MTTEFVRQDLAQNSSSTGEPDRVRVIREGVASYLPDIDPEETGEWLESFD
MAB_1884c|M.abscessus_ATCC_199 ------------------------MIREGVASYLPDIDPDETGEWLESFD
TH_1339|M.thermoresistible__bu LTTEFVRQDLAQNSKSTTGHGRVRVIRDGVAAYLPDIDPEETAEWLESFD
MSMEG_4323|M.smegmatis_MC2_155 MTTEFVRQDLAQNSSTAAEPDRVRVIREGVASYLPDIDTEETAEWLESFD
Mb2265|M.bovis_AF2122/97 -----------------------------MASYLPDIDPEETSEWLESFD
Rv2241|M.tuberculosis_H37Rv -----------------------------MASYLPDIDPEETSEWLESFD
MLBr_01651|M.leprae_Br4923 MTIEFARPDLAKNPSSTNESNSVRVIREGVASYLPDIDPEETAEWLESFD
MAV_2196|M.avium_104 MTTEFVRHDLATNPTGPAEPDRVRVIREGVASYLPDIDPEETSEWLESFD
MMAR_3334|M.marinum_M MTTEFVRHDLAKTSSSASEPDRVRVIREGVASYLPDIDPEETSEWLESFD
MUL_1308|M.ulcerans_Agy99 MTTEFVRHDLAKTSSSASEPDRVRVIREGVASYLPDIDPEETSEWLESFD
:*:******.:**.*******
Mvan_3752|M.vanbaalenii_PYR-1 DLLERSGPARARYLMLRLLERSREKRVAIPALTSTDYVNTIPTELEPWFP
Mflv_2781|M.gilvum_PYR-GCK DLLERSGPARARYLMLRLLERAGEQRVAIPALTSTDYVNTIPTELEPWFP
MAB_1884c|M.abscessus_ATCC_199 GLLARSGPARARYLMLRLLERANAGRVAIPALTSTDYVNTIPTENEPWFP
TH_1339|M.thermoresistible__bu QLVERSGPARARYLMLRMLERAREQRVAIPALTSTDYVNTIPTENEPWFP
MSMEG_4323|M.smegmatis_MC2_155 ELLERSGPARARYLMLRLLERAGEQRVAIPALTSTDYVNTIPTELEPWFP
Mb2265|M.bovis_AF2122/97 TLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVNTIPTELEPWFP
Rv2241|M.tuberculosis_H37Rv TLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVNTIPTELEPWFP
MLBr_01651|M.leprae_Br4923 ELLKHSGPSRARYLILRLLERAGEQRVTIPALTWTDYVNTIPTELEPWFP
MAV_2196|M.avium_104 ELLERSGPSRARYLMLRLLERAGEQRVAIPSLTSTDYVNTIPTELEPWFP
MMAR_3334|M.marinum_M ALLEHSGPARARYLMLRLLERAGEQRVAIPSLTSTDYVNTIPTELEPWFP
MUL_1308|M.ulcerans_Agy99 ALLEHSGPARARYLMLRLLERAGEQRVAIPSLTSTDYVNTIPTELEPWFP
*: :.**:*****:**:***: **:**:** ********** *****
Mvan_3752|M.vanbaalenii_PYR-1 GDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN
Mflv_2781|M.gilvum_PYR-GCK GDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN
MAB_1884c|M.abscessus_ATCC_199 GDEDTERRFRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN
TH_1339|M.thermoresistible__bu GDEDTERRFRLWIRWNAAIMVHRAQRPGVGVGGHISTYASSATLYEVGFN
MSMEG_4323|M.smegmatis_MC2_155 GDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSATLYEVGFN
Mb2265|M.bovis_AF2122/97 GDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN
Rv2241|M.tuberculosis_H37Rv GDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN
MLBr_01651|M.leprae_Br4923 GDEDIERRYRTWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN
MAV_2196|M.avium_104 GDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN
MMAR_3334|M.marinum_M GDEDVERRYRTWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN
MUL_1308|M.ulcerans_Agy99 GDEDVERRYRTWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN
**** ***:* *******************************:*******
Mvan_3752|M.vanbaalenii_PYR-1 HFFRGKSHPGGGDQIFIQGHASPGIYARAYLEGRLSADQLDGFRQEHSHP
Mflv_2781|M.gilvum_PYR-GCK HFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTTDQLDGFRQEHSHA
MAB_1884c|M.abscessus_ATCC_199 HFFRGNAHPGGGDQIFIQGHASPGIYARAFLEGRLTTDQLDGFRQEKSHP
TH_1339|M.thermoresistible__bu HFFRGKAHPGGGDQVFIQGHASPGIYARAFLEGRLTADQLDGFRQEHSHP
MSMEG_4323|M.smegmatis_MC2_155 HFFRGKSHPGGGDHVFIQGHASPGIYARAFLEGRLTTDQLDGFRQEHSHS
Mb2265|M.bovis_AF2122/97 HFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHV
Rv2241|M.tuberculosis_H37Rv HFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHV
MLBr_01651|M.leprae_Br4923 HFFRGKSHPSGGDQVFIQGHASPGIYARAFLEGRLSADQLDGFRQEHSHP
MAV_2196|M.avium_104 HFFRGKSHPGGGDQIFIQGHASPGIYARAFLEGRLTADQLDGFRQEHSHA
MMAR_3334|M.marinum_M HFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLSADQLDGFRQEHSHP
MUL_1308|M.ulcerans_Agy99 HFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLSADQLDGFRQEHSHP
*****::**.***::**************:*****:::********:**
Mvan_3752|M.vanbaalenii_PYR-1 GGGLPSYPHPRLMPDFWEFPTVSMGLGPMNAIYQARFNHYLHDRGIKDTS
Mflv_2781|M.gilvum_PYR-GCK GGGLPSYPHPRLMPDFWEFPTVSMGLGPMNAIYQARFNHYLHDRDIKDTS
MAB_1884c|M.abscessus_ATCC_199 GGGLPSYPHPRLMPDFWQFPTVSMGLGPMNAIMQARFNHYLRDRGIKDTS
TH_1339|M.thermoresistible__bu GGGLPSYPHPRLMPDFWEFPTVSMGLGPINAIFQARFNRYLHNRGIKDTS
MSMEG_4323|M.smegmatis_MC2_155 GGGLPSYPHPRLMPDFWEFPTVSMGLGPMNAIYQARFNHYLHDRGIKDTS
Mb2265|M.bovis_AF2122/97 GGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTS
Rv2241|M.tuberculosis_H37Rv GGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTS
MLBr_01651|M.leprae_Br4923 GGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNRYLHDRGIKDTS
MAV_2196|M.avium_104 GGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTS
MMAR_3334|M.marinum_M GGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTS
MUL_1308|M.ulcerans_Agy99 GGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTS
*****************:**********:*** *****:**::*.*****
Mvan_3752|M.vanbaalenii_PYR-1 KQHVWAFLGDGEMDEPESRGLIQVAANEALDNLTFVVNCNLQRLDGPVRG
Mflv_2781|M.gilvum_PYR-GCK KQHVWAFLGDGEMDEPESRGLIQVAANEGLDNLTFVVNCNLQRLDGPVRG
MAB_1884c|M.abscessus_ATCC_199 DQRVWAFLGDGEMDEPESRGLAHIAATEGLDNLTFVVNCNLQRLDGPVRG
TH_1339|M.thermoresistible__bu GQHVWCFLGDGEMDEPESRGAAHVAALEGLDNLTFVVNCNLQRLDGPVRG
MSMEG_4323|M.smegmatis_MC2_155 DQHVWAFLGDGEMDEPESRGLIQVAANEALDNLTFVINCNLQRLDGPVRG
Mb2265|M.bovis_AF2122/97 DQHVWCFLGDGEMDEPESRGLAHVGALEGLDNLTFVINCNLQRLDGPVRG
Rv2241|M.tuberculosis_H37Rv DQHVWCFLGDGEMDEPESRGLAHVGALEGLDNLTFVINCNLQRLDGPVRG
MLBr_01651|M.leprae_Br4923 DQHVWCFLGDGEMDEPESRGLAHVASLEDLDNLIFVINCNLQRLDGPVRG
MAV_2196|M.avium_104 DQHVWCFLGDGEMDEPESRGLIQVAANEALDNLTFVINCNLQRLDGPVRG
MMAR_3334|M.marinum_M DQHVWCFLGDGEMDEPESRGLAHMGALEGLDNLTFVINCNLQRLDGPVRG
MUL_1308|M.ulcerans_Agy99 DQHVWCFLGDGEMDEPESRGLAHMGALEGLDNLTFVINCNLQRLDGPVRG
*:**.************** ::.: * **** **:*************
Mvan_3752|M.vanbaalenii_PYR-1 NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDG
Mflv_2781|M.gilvum_PYR-GCK NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDG
MAB_1884c|M.abscessus_ATCC_199 NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTADG
TH_1339|M.thermoresistible__bu NGKIIQELEAFFRGAGWNVIKVVWGREWDALLHADKDGALVNLMNTTPDG
MSMEG_4323|M.smegmatis_MC2_155 NGKIIQELESFFRGAGWNVIKVVWGREWDVLLHADRDGALVNLMNSTPDG
Mb2265|M.bovis_AF2122/97 NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDRALVNLMNTTPDG
Rv2241|M.tuberculosis_H37Rv NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDG
MLBr_01651|M.leprae_Br4923 NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVDLMNATPDG
MAV_2196|M.avium_104 NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDG
MMAR_3334|M.marinum_M NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNSTPDG
MUL_1308|M.ulcerans_Agy99 NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNSTPDG
*********:*******************.*****:* ***:***:*.**
Mvan_3752|M.vanbaalenii_PYR-1 DYQTYKANDGAYVRDHFFGRDPRTKALVENMTDREIWNLKRGGHDYRKVY
Mflv_2781|M.gilvum_PYR-GCK DYQTYKANDGSYVRDHFFGRDPRTKALVEPMTDAEIWNLKRGGHDYRKVY
MAB_1884c|M.abscessus_ATCC_199 DYQTYKANDGAYVREHFFGRDPRTKELVKDLTDAQVWNLKRGGHDYRKVY
TH_1339|M.thermoresistible__bu DYQTYKANDGAYVREHFFGRDPRTKALVQNMTDQEIWNLKRGGHDYRKVY
MSMEG_4323|M.smegmatis_MC2_155 DYQTYKANDGAYVRDHFFGRDPRTKALVADMSDQEIWNLKRGGHDYRKVY
Mb2265|M.bovis_AF2122/97 DYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNLKRGGHDYRKVY
Rv2241|M.tuberculosis_H37Rv DYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNLKRGGHDYRKVY
MLBr_01651|M.leprae_Br4923 DYQTYKANDGRFVRDHFFGRDPRTKALVEHMSDQEIWNLKRGGHDYRKVY
MAV_2196|M.avium_104 DYQTYKANDGAYVRDHFFGRDPRTKALVENMTDAEIWNLKRGGHDYRKVY
MMAR_3334|M.marinum_M DYQTYKANDGAYVRDHFFGRDPRTKALVANMSDQEIWNLKRGGHDYRKVY
MUL_1308|M.ulcerans_Agy99 DYQTYKANDGAYVRDHFFGRDPRTKALVANMSDQEIWNLKRGGHDYRKVY
********** :**:********** ** ::* ::**************
Mvan_3752|M.vanbaalenii_PYR-1 AAYHAALEHKGQPTVILAKTIKGYTLGKHFEGRNATHQMKKLALQDLKDF
Mflv_2781|M.gilvum_PYR-GCK AAYHAAMEHKGQPTVILAKTIKGYTLGKHFEGRNATHQMKKLALQDLKDF
MAB_1884c|M.abscessus_ATCC_199 AAYRAATEHKGQPTVILAKTIKGYTLGKHFEGRNATHQMKKLTLDDLKDF
TH_1339|M.thermoresistible__bu AAYRAAVEHKGQPTVILAKTIKGYSLGANFQGRNATHQMKKLALDDLKHF
MSMEG_4323|M.smegmatis_MC2_155 AAYRAAMEHKGQPTVILAKTIKGYTLGQHFEGRNATHQMKKLALEDLKNF
Mb2265|M.bovis_AF2122/97 AAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKEF
Rv2241|M.tuberculosis_H37Rv AAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKEF
MLBr_01651|M.leprae_Br4923 ASYRAAVDHKGQPTVILAKTIKGYALGKHFESRNATHQMKKLTLEDLKEF
MAV_2196|M.avium_104 AAYRAAVDHKGQPTVILAKTIKGYSLGAHFQGRNATHQMKKLALEDLKHF
MMAR_3334|M.marinum_M AAYRAAVDHKGQPTVILAKTIKGYSLGAHFQGRNATHQMKKLALADLKRF
MUL_1308|M.ulcerans_Agy99 AAYRAAVDHKGQPTVILAKTIKGYSLGAHFQGRNATHQMKKLALADLKRF
*:*:** :****************:** :*:.**********:* *** *
Mvan_3752|M.vanbaalenii_PYR-1 RDAQRIPVSDEQLEADPYLPPYYHPGPEAPEIRYMLDRRRALGGFLPERR
Mflv_2781|M.gilvum_PYR-GCK RDVQRIPVSDSQLEENPYLPPYYHPGPEAPEIRYMLDRRRALGGFLPERR
MAB_1884c|M.abscessus_ATCC_199 RDKQRIPISDAQLEENPYLPPYYHPGPEAPEIRYMLDRRRALGGFVPSRR
TH_1339|M.thermoresistible__bu RDAMRIPISDEQLEENPYLPPYYHPGPEAPEIRYMLERRRALGGFVPERR
MSMEG_4323|M.smegmatis_MC2_155 RDVTRVPVSDAQLEEDPYLPPYYHPGPEAPEIRYLLERRRALGGFVPSRR
Mb2265|M.bovis_AF2122/97 RDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERR
Rv2241|M.tuberculosis_H37Rv RDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERR
MLBr_01651|M.leprae_Br4923 RDTQRIPISDTELEENPYLPPYYHPGPDSPEIRYLLDRRRALGGFLPERR
MAV_2196|M.avium_104 RDAMRIPISDAQLDENPYLPPYYHPGSDAPEIRYMLDRRRTLGGFLPERR
MMAR_3334|M.marinum_M RDSMRIPVSDAQLDEDPYLPPYYHPGSDAPEIRYMLDRRRTLGGFLPERP
MUL_1308|M.ulcerans_Agy99 RDSMRIPVSDAQLDEDPYLPPYYHPGSDAPEIRYMLDRRRTLGGFLPERP
** *:*:** :*: :********** ::*****:*:***:****:*.*
Mvan_3752|M.vanbaalenii_PYR-1 TKSRALTLPGRDVYKALKKGSGKQEVATTMATVRTFKELLRDKNIGSRIV
Mflv_2781|M.gilvum_PYR-GCK TKTKALTLPGRDTYKALKKGSGKQEVATTMATVRTFKELLRDKNIGWRIV
MAB_1884c|M.abscessus_ATCC_199 TTSRPLTLPGSETYASIKKGSGKQEVATTMALVRTFKELLRDKNIGNRIV
TH_1339|M.thermoresistible__bu TTSKALRIPGSDIFRSVRKGSGNQEVATTMATVRTFREVLRDKELGWRIV
MSMEG_4323|M.smegmatis_MC2_155 TKSKPLALPGSDTYKALKKGSGSQAVATTMATVRTFKELLRDKNIGPRIV
Mb2265|M.bovis_AF2122/97 TKSKALTLPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIV
Rv2241|M.tuberculosis_H37Rv TKSKALTLPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIV
MLBr_01651|M.leprae_Br4923 TKSGALTLPGRDTYAALKTGSGQQEVATTMAIVRTFKEVLRHKEVGPRIV
MAV_2196|M.avium_104 TKAKALRLPGRDIYAALKKGSGTQEVATTMATVRTFKEVLRDKEIGPRIV
MMAR_3334|M.marinum_M TKAKTLTLPGPDAYKVLKKGSGQQEVATTMALVRTFKELLRDKNIGNRIV
MUL_1308|M.ulcerans_Agy99 TKAKTLTLPGPDAYKVLKKGSGQQEVATTMALVRTFKELLRDKNIGNRIV
*.: .* :** : : ::.*** * ****** ****:*:**.*::* ***
Mvan_3752|M.vanbaalenii_PYR-1 PIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDAELMLAYKESEIGQILH
Mflv_2781|M.gilvum_PYR-GCK PIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDAELMLAYKESEVGQILH
MAB_1884c|M.abscessus_ATCC_199 PIIPDEARTFGMDSWFPSLKIYNRNGQLYTSVDAELMLAYKESAQGQILH
TH_1339|M.thermoresistible__bu PIIPDEARTFGMDSWFPSLKIYNPNGQLYTSVDADLMLAYKESEAGQILH
MSMEG_4323|M.smegmatis_MC2_155 PIIPDEARTFGMDSWFPSLKIYNRNGQLYTSVDSELMLAYKESEVGQILH
Mb2265|M.bovis_AF2122/97 PIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDADLMLAYKESEVGQILH
Rv2241|M.tuberculosis_H37Rv PIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDADLMLAYKESEVGQILH
MLBr_01651|M.leprae_Br4923 PIIPDEARTFGMDSWFPSLKIYNHNGQLYTAVDAQLMLAYKESEVGQILH
MAV_2196|M.avium_104 PIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDAELMLAYKESEVGQILH
MMAR_3334|M.marinum_M PIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDAELMLAYKESHVGQILH
MUL_1308|M.ulcerans_Agy99 PIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDAELMLAYKESHVGQILH
*********************** ******:**::******** *****
Mvan_3752|M.vanbaalenii_PYR-1 EGINEAGSTASFTAVGTSYATHNEPMIPIYIFYSMFGFQRTGDGLWAAAD
Mflv_2781|M.gilvum_PYR-GCK EGINEAGSTASFTAVGTSYATHNEPMIPIYIFYSMFGFQRTGDGLWAAAD
MAB_1884c|M.abscessus_ATCC_199 EGINEAGSTASFTAVGTAYSTHDEPMIPLYIFYSMFGFQRTGDGLWAAAD
TH_1339|M.thermoresistible__bu EGINEAGSSASFIAAGTSYATHNEPMIPIYIFYSMFGFQRTGDNLWAAGD
MSMEG_4323|M.smegmatis_MC2_155 EGINEAGSTSSFTAVGTSYSTHDEPMIPIYIFYSMFGFQRTGDGLWAAAD
Mb2265|M.bovis_AF2122/97 EGINEAGSVGSFIAAGTSYATHNEPMIPIYIFYSMFGFQRTGDSFWAAAD
Rv2241|M.tuberculosis_H37Rv EGINEAGSVGSFIAAGTSYATHNEPMIPIYIFYSMFGFQRTGDSFWAAAD
MLBr_01651|M.leprae_Br4923 EGIDEAGSVGSFIAAGTSYSTHNEPMIPIYIFYSMFGFQRTGDGLWAAAD
MAV_2196|M.avium_104 EGINEAGSVGSFIAAGTSYATHNEPMIPIYIFYSMFGFQRTGDGLWAAAD
MMAR_3334|M.marinum_M EGINEAGSVGSFTAAGTSYATHNEPMIPIYIFYSMFGFQRTGDSFWAAAD
MUL_1308|M.ulcerans_Agy99 EGINEAGSVGSFTAAGTSYATHNEPMIPIYIFYSMFGFQRTGDSFWAAAD
***:**** .** *.**:*:**:*****:**************.:***.*
Mvan_3752|M.vanbaalenii_PYR-1 QMARGFVLGATAGRTTLVGEGLQHADGHSLLLASTNPAVVAYDPAFAYEI
Mflv_2781|M.gilvum_PYR-GCK QMARGFVLGATAGRTTLVGEGLQHADGHSLLLAATNPAVVSYDPAFAFEI
MAB_1884c|M.abscessus_ATCC_199 QMARGFVLGATAGRTTLTGEGLQHADGHSLLLASTNPAVVAYDPAFAYEI
TH_1339|M.thermoresistible__bu QMARGFLLGATAGRTTLVGEGLQHADGHSLLLASTNPAVVAYDPAFAYEI
MSMEG_4323|M.smegmatis_MC2_155 QMARGFVLGATAGRTTLTGEGLQHADGHSLLLASTNPAAVTYDPAFAYEI
Mb2265|M.bovis_AF2122/97 QMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVAYDPAFAYEI
Rv2241|M.tuberculosis_H37Rv QMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVAYDPAFAYEI
MLBr_01651|M.leprae_Br4923 QMARGFLLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVTYDPAFAYEI
MAV_2196|M.avium_104 QMTRGFLLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVAYDPAFAYEI
MMAR_3334|M.marinum_M QMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVSYDPAFAYEL
MUL_1308|M.ulcerans_Agy99 QMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVSYDPAFAYEL
**:***:**********.***************:****.*:******:*:
Mvan_3752|M.vanbaalenii_PYR-1 AYIIESGLHRMYGENPENVYFYMTIYNEPYVQPAEPDGLDVEGLLRGMYR
Mflv_2781|M.gilvum_PYR-GCK AYIIESGLQRMYGDNPENVYFYMTIYNEPYVQPAEPEGIDVEGLLRGMYR
MAB_1884c|M.abscessus_ATCC_199 AHIVEHGLQRMYGENSENVYFYITLYNEPYVQPAEPENVDTEGILRGIYK
TH_1339|M.thermoresistible__bu AHIVESGLHRMYGENPENVFFYLTIYNEPYRQPAEPEDLDVEGLLRGIYR
MSMEG_4323|M.smegmatis_MC2_155 AHIIESGLQRMYGEDPENVFFYLTIYNEPYQQPAEPENLDVEALLKGLYL
Mb2265|M.bovis_AF2122/97 AYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIYR
Rv2241|M.tuberculosis_H37Rv AYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIYR
MLBr_01651|M.leprae_Br4923 AYIVESGLTRMFGEDPENVFFYITVYNEPYPQPPEPENFDPDGVLRGMYR
MAV_2196|M.avium_104 AYIVESGLARMFGENPEDVYFYITVYNEPYVQPPEPENFDPEGLLRGLYR
MMAR_3334|M.marinum_M AYIIENGLSRMFGENPENIYFYITVYNEPYVQPAEPENFDPEGVLRGMYR
MUL_1308|M.ulcerans_Agy99 AYIIENGLSRMFGENPENIYFYITVYNEPYVQPAEPENFDPEGVLRGMYR
*:*:* ** ** *::.*:::**:*:***** **.**:..* :.:*:*:*
Mvan_3752|M.vanbaalenii_PYR-1 YQAAPEKRTNAAQILVSGVGMPSALKAAELLAQEWDVAADVWSVTSWGEL
Mflv_2781|M.gilvum_PYR-GCK YQAAPQKKSNSAQILVSGVSMPSALKAAEMLAEEWDVSADVWSVTSWGEL
MAB_1884c|M.abscessus_ATCC_199 FRAAPEARTHRANILASGVSVPDALRAADLLAEQWDVAADVWSVTSWGEL
TH_1339|M.thermoresistible__bu YRRAPQKRTHTAQILASGVAMPEALRAADLLAEDWDVAADVWSVTSWGEL
MSMEG_4323|M.smegmatis_MC2_155 YRPAPEKRAKSAQILASGVAMPEALRAADLLASDWDVAADVWSVTSWGEL
Mb2265|M.bovis_AF2122/97 YHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGEL
Rv2241|M.tuberculosis_H37Rv YHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGEL
MLBr_01651|M.leprae_Br4923 YYTAKEQRSNKAHILASGVSMPAALTAAEMLSTQWDVAADVWSVTSWGEL
MAV_2196|M.avium_104 YHVATEQRANKAQILASGVAMPSALSAAKMLADEWDVAADVWSVTSWGEL
MMAR_3334|M.marinum_M YRAATKQCAHKAQLLASGVSMPDALKAAQMLADEWDVATDVWSVTSWSEL
MUL_1308|M.ulcerans_Agy99 YRAATKQCAHKAQLLASGVSMPDALKAAQMLADEWDVATDVWSVTSWSEL
: * : :: *::*.***.:* ** **.:*: :***::********.**
Mvan_3752|M.vanbaalenii_PYR-1 NRDGVAIEREKLRHPELPAATPYVTKMLAEAA----GPVVAVSDWMRAVP
Mflv_2781|M.gilvum_PYR-GCK NREGVAIEKERLRHPDREVATPYVTEALAGAE----GPVVAVSDWMRAVP
MAB_1884c|M.abscessus_ATCC_199 NRDGLAIDHQALRHPDRPKGVPYVTKALEGAQ----GPKVAVSDWMHAVP
TH_1339|M.thermoresistible__bu NRDGVTIEKQRLRHPDQPADTPYVTRALADAS----GPVVAVSDWMRAVP
MSMEG_4323|M.smegmatis_MC2_155 NREGVAIEKHRLRHPDEPAGTPHVTSALADAA----GPVIAVSDWMRAVP
Mb2265|M.bovis_AF2122/97 NRDGVAIETEKLRHPDRPAGVPYVTRALENAR----GPVIAVSDWMRAVP
Rv2241|M.tuberculosis_H37Rv NRDGVAIETEKLRHPDRPAGVPYVTRALENAR----GPVIAVSDWMRAVP
MLBr_01651|M.leprae_Br4923 NRDGMSIETARLRYPDQPTSVPYVTQVLSEARSDNAGPVIAVSDWMRAVP
MAV_2196|M.avium_104 NRDGVAIDRARLRHPDRPAGVPYVTQALSDAS----GPVVAVSDWMRAVP
MMAR_3334|M.marinum_M NRDGVSVERHRLRHPGEPAGVAYVTTALEGTS----GPVVAVSDWMRAVP
MUL_1308|M.ulcerans_Agy99 NRDGVSVERHRLRHPGEPAGVAYVTTALEGTS----GPVVAVSDWMRAVP
**:*:::: **:* ..:** * : ** :******:***
Mvan_3752|M.vanbaalenii_PYR-1 EQIRPWVPGTYITLGTDGFGFSDTRPAARRYYNTDAESVVVAVLEGLARD
Mflv_2781|M.gilvum_PYR-GCK EQIRPWVPGTYVTLGTDGFGFSDTRPAARRYYNTDAESIVVAVLEGLARD
MAB_1884c|M.abscessus_ATCC_199 EQIRPWVPGMYRTLGADGFGISDTRPAARRFFNTDAESVVVAVLEALADE
TH_1339|M.thermoresistible__bu EQIRAWVPGTYITLGTDGFGFSDTRPAARRYFNTDAESVAVAVLEGLARD
MSMEG_4323|M.smegmatis_MC2_155 EQIRPWVPGTYVTLGTDGFGFSDTRPAARRYFNTDAESVVVAVLQGLARD
Mb2265|M.bovis_AF2122/97 EQIRPWVPGTYLTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALAGD
Rv2241|M.tuberculosis_H37Rv EQIRPWVPGTYLTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALAGD
MLBr_01651|M.leprae_Br4923 EQIRPWVPGTYVTLGTDGFGFSDTRTATRRYFNTDAESQVVAVLEALARD
MAV_2196|M.avium_104 EQIRPWVPGTYVTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALARD
MMAR_3334|M.marinum_M EQIRPWVPGTYVTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALARD
MUL_1308|M.ulcerans_Agy99 EQIRPWVPGTYVTLGTDGFGFSNTRPAARRYFNTDAESQVVAVLEALARD
****.**** * ***:****:*:**.*:**::****** .****:.** :
Mvan_3752|M.vanbaalenii_PYR-1 GNIDISVAVEAAKKYEIDDVMAAPEQTSDPGVA---
Mflv_2781|M.gilvum_PYR-GCK GNIDISAAVDAARRYEIDDVMAAPEQTSDPGVA---
MAB_1884c|M.abscessus_ATCC_199 GSVDRQVAVTAAAQYKIDDVSAADVSYKDTGSA---
TH_1339|M.thermoresistible__bu GNLDRSVAVEAARRYRIDDVMAAPEQTSDPGVA---
MSMEG_4323|M.smegmatis_MC2_155 GEIDASVAAQAAEQYRIDDVSAAGVSYADTGSA---
Mb2265|M.bovis_AF2122/97 GEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPGA--
Rv2241|M.tuberculosis_H37Rv GEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPGA--
MLBr_01651|M.leprae_Br4923 GEIDPSVPVAATRQYQIDDVQAAPEQTSDPGPGVQN
MAV_2196|M.avium_104 GEIDPSVPVAAARQYRIDDVLAAPEQTSDPGVA---
MMAR_3334|M.marinum_M GEIDESVAVTAARQYRIDDVQAAPKQTSDSGVA---
MUL_1308|M.ulcerans_Agy99 GEIDESMAVTAARQYRIDDVQAAPKQTSDSGVA---
*.:* . .. *: :*.**** ** . *.* .