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LTTDFARHDLAQNSNSASEPDRVRVIREGVASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLE RAGEQRVAIPALTSTDYVNTIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYAS SAALYEVGFNHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPHP RLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESRGLAHVGALEGL DNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDG DYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKT IKGYALGKHFEGRNATHQMKKLTLEDLKEFRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRR ALGGFVPERRTKSKALTLPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTF GMDSWFPSLKIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPIY IFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVAYDPAFAYEI AYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIYRYHAATEQRTNKAQILASGVA MPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIETEKLRHPDRPAGVPYVTRALENARGPVIAVSD WMRAVPEQIRPWVPGTYLTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQ YRIDDVAAAPEQTTDPGPGA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2241 | aceE | - | 100% (901) | pyruvate dehydrogenase subunit E1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2265 | aceE | 0.0 | 99.89% (901) | pyruvate dehydrogenase subunit E1 |
| M. gilvum PYR-GCK | Mflv_2781 | aceE | 0.0 | 88.20% (898) | pyruvate dehydrogenase subunit E1 |
| M. leprae Br4923 | MLBr_01651 | aceE | 0.0 | 89.60% (904) | pyruvate dehydrogenase subunit E1 |
| M. abscessus ATCC 19977 | MAB_1884c | aceE | 0.0 | 84.41% (898) | pyruvate dehydrogenase subunit E1 |
| M. marinum M | MMAR_3334 | aceE | 0.0 | 90.31% (898) | pyruvate dehydrogenase E1 component AceE |
| M. avium 104 | MAV_2196 | aceE | 0.0 | 92.87% (898) | pyruvate dehydrogenase subunit E1 |
| M. smegmatis MC2 155 | MSMEG_4323 | aceE | 0.0 | 86.64% (898) | pyruvate dehydrogenase subunit E1 |
| M. thermoresistible (build 8) | TH_1339 | aceE | 0.0 | 86.53% (898) | Probable pyruvate dehydrogenase E1 component aceE (PYRUVATE |
| M. ulcerans Agy99 | MUL_1308 | aceE | 0.0 | 90.09% (898) | pyruvate dehydrogenase subunit E1 |
| M. vanbaalenii PYR-1 | Mvan_3752 | aceE | 0.0 | 87.97% (898) | pyruvate dehydrogenase subunit E1 |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_1884c|M.abscessus_ATCC_199 ------------------------MIREGVASYLPDIDPDETGEWLESFD
TH_1339|M.thermoresistible__bu LTTEFVRQDLAQNSKSTTGHGRVRVIRDGVAAYLPDIDPEETAEWLESFD
MSMEG_4323|M.smegmatis_MC2_155 MTTEFVRQDLAQNSSTAAEPDRVRVIREGVASYLPDIDTEETAEWLESFD
Mflv_2781|M.gilvum_PYR-GCK MTTEFVRQDLAQNSSSTGEPDRVRVIREGVASYLPDIDPEETGEWLESFD
Mvan_3752|M.vanbaalenii_PYR-1 -----MRQDLAQNSGSTAEPDRVRVIREGVASYLPDIDPEETGEWLESFD
Rv2241|M.tuberculosis_H37Rv -----------------------------MASYLPDIDPEETSEWLESFD
Mb2265|M.bovis_AF2122/97 -----------------------------MASYLPDIDPEETSEWLESFD
MLBr_01651|M.leprae_Br4923 MTIEFARPDLAKNPSSTNESNSVRVIREGVASYLPDIDPEETAEWLESFD
MAV_2196|M.avium_104 MTTEFVRHDLATNPTGPAEPDRVRVIREGVASYLPDIDPEETSEWLESFD
MMAR_3334|M.marinum_M MTTEFVRHDLAKTSSSASEPDRVRVIREGVASYLPDIDPEETSEWLESFD
MUL_1308|M.ulcerans_Agy99 MTTEFVRHDLAKTSSSASEPDRVRVIREGVASYLPDIDPEETSEWLESFD
:*:******.:**.*******
MAB_1884c|M.abscessus_ATCC_199 GLLARSGPARARYLMLRLLERANAGRVAIPALTSTDYVNTIPTENEPWFP
TH_1339|M.thermoresistible__bu QLVERSGPARARYLMLRMLERAREQRVAIPALTSTDYVNTIPTENEPWFP
MSMEG_4323|M.smegmatis_MC2_155 ELLERSGPARARYLMLRLLERAGEQRVAIPALTSTDYVNTIPTELEPWFP
Mflv_2781|M.gilvum_PYR-GCK DLLERSGPARARYLMLRLLERAGEQRVAIPALTSTDYVNTIPTELEPWFP
Mvan_3752|M.vanbaalenii_PYR-1 DLLERSGPARARYLMLRLLERSREKRVAIPALTSTDYVNTIPTELEPWFP
Rv2241|M.tuberculosis_H37Rv TLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVNTIPTELEPWFP
Mb2265|M.bovis_AF2122/97 TLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVNTIPTELEPWFP
MLBr_01651|M.leprae_Br4923 ELLKHSGPSRARYLILRLLERAGEQRVTIPALTWTDYVNTIPTELEPWFP
MAV_2196|M.avium_104 ELLERSGPSRARYLMLRLLERAGEQRVAIPSLTSTDYVNTIPTELEPWFP
MMAR_3334|M.marinum_M ALLEHSGPARARYLMLRLLERAGEQRVAIPSLTSTDYVNTIPTELEPWFP
MUL_1308|M.ulcerans_Agy99 ALLEHSGPARARYLMLRLLERAGEQRVAIPSLTSTDYVNTIPTELEPWFP
*: :.**:*****:**:***: **:**:** ********** *****
MAB_1884c|M.abscessus_ATCC_199 GDEDTERRFRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN
TH_1339|M.thermoresistible__bu GDEDTERRFRLWIRWNAAIMVHRAQRPGVGVGGHISTYASSATLYEVGFN
MSMEG_4323|M.smegmatis_MC2_155 GDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSATLYEVGFN
Mflv_2781|M.gilvum_PYR-GCK GDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN
Mvan_3752|M.vanbaalenii_PYR-1 GDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN
Rv2241|M.tuberculosis_H37Rv GDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN
Mb2265|M.bovis_AF2122/97 GDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN
MLBr_01651|M.leprae_Br4923 GDEDIERRYRTWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN
MAV_2196|M.avium_104 GDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN
MMAR_3334|M.marinum_M GDEDVERRYRTWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN
MUL_1308|M.ulcerans_Agy99 GDEDVERRYRTWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN
**** ***:* *******************************:*******
MAB_1884c|M.abscessus_ATCC_199 HFFRGNAHPGGGDQIFIQGHASPGIYARAFLEGRLTTDQLDGFRQEKSHP
TH_1339|M.thermoresistible__bu HFFRGKAHPGGGDQVFIQGHASPGIYARAFLEGRLTADQLDGFRQEHSHP
MSMEG_4323|M.smegmatis_MC2_155 HFFRGKSHPGGGDHVFIQGHASPGIYARAFLEGRLTTDQLDGFRQEHSHS
Mflv_2781|M.gilvum_PYR-GCK HFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTTDQLDGFRQEHSHA
Mvan_3752|M.vanbaalenii_PYR-1 HFFRGKSHPGGGDQIFIQGHASPGIYARAYLEGRLSADQLDGFRQEHSHP
Rv2241|M.tuberculosis_H37Rv HFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHV
Mb2265|M.bovis_AF2122/97 HFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHV
MLBr_01651|M.leprae_Br4923 HFFRGKSHPSGGDQVFIQGHASPGIYARAFLEGRLSADQLDGFRQEHSHP
MAV_2196|M.avium_104 HFFRGKSHPGGGDQIFIQGHASPGIYARAFLEGRLTADQLDGFRQEHSHA
MMAR_3334|M.marinum_M HFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLSADQLDGFRQEHSHP
MUL_1308|M.ulcerans_Agy99 HFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLSADQLDGFRQEHSHP
*****::**.***::**************:*****:::********:**
MAB_1884c|M.abscessus_ATCC_199 GGGLPSYPHPRLMPDFWQFPTVSMGLGPMNAIMQARFNHYLRDRGIKDTS
TH_1339|M.thermoresistible__bu GGGLPSYPHPRLMPDFWEFPTVSMGLGPINAIFQARFNRYLHNRGIKDTS
MSMEG_4323|M.smegmatis_MC2_155 GGGLPSYPHPRLMPDFWEFPTVSMGLGPMNAIYQARFNHYLHDRGIKDTS
Mflv_2781|M.gilvum_PYR-GCK GGGLPSYPHPRLMPDFWEFPTVSMGLGPMNAIYQARFNHYLHDRDIKDTS
Mvan_3752|M.vanbaalenii_PYR-1 GGGLPSYPHPRLMPDFWEFPTVSMGLGPMNAIYQARFNHYLHDRGIKDTS
Rv2241|M.tuberculosis_H37Rv GGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTS
Mb2265|M.bovis_AF2122/97 GGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTS
MLBr_01651|M.leprae_Br4923 GGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNRYLHDRGIKDTS
MAV_2196|M.avium_104 GGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTS
MMAR_3334|M.marinum_M GGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTS
MUL_1308|M.ulcerans_Agy99 GGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTS
*****************:**********:*** *****:**::*.*****
MAB_1884c|M.abscessus_ATCC_199 DQRVWAFLGDGEMDEPESRGLAHIAATEGLDNLTFVVNCNLQRLDGPVRG
TH_1339|M.thermoresistible__bu GQHVWCFLGDGEMDEPESRGAAHVAALEGLDNLTFVVNCNLQRLDGPVRG
MSMEG_4323|M.smegmatis_MC2_155 DQHVWAFLGDGEMDEPESRGLIQVAANEALDNLTFVINCNLQRLDGPVRG
Mflv_2781|M.gilvum_PYR-GCK KQHVWAFLGDGEMDEPESRGLIQVAANEGLDNLTFVVNCNLQRLDGPVRG
Mvan_3752|M.vanbaalenii_PYR-1 KQHVWAFLGDGEMDEPESRGLIQVAANEALDNLTFVVNCNLQRLDGPVRG
Rv2241|M.tuberculosis_H37Rv DQHVWCFLGDGEMDEPESRGLAHVGALEGLDNLTFVINCNLQRLDGPVRG
Mb2265|M.bovis_AF2122/97 DQHVWCFLGDGEMDEPESRGLAHVGALEGLDNLTFVINCNLQRLDGPVRG
MLBr_01651|M.leprae_Br4923 DQHVWCFLGDGEMDEPESRGLAHVASLEDLDNLIFVINCNLQRLDGPVRG
MAV_2196|M.avium_104 DQHVWCFLGDGEMDEPESRGLIQVAANEALDNLTFVINCNLQRLDGPVRG
MMAR_3334|M.marinum_M DQHVWCFLGDGEMDEPESRGLAHMGALEGLDNLTFVINCNLQRLDGPVRG
MUL_1308|M.ulcerans_Agy99 DQHVWCFLGDGEMDEPESRGLAHMGALEGLDNLTFVINCNLQRLDGPVRG
*:**.************** ::.: * **** **:*************
MAB_1884c|M.abscessus_ATCC_199 NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTADG
TH_1339|M.thermoresistible__bu NGKIIQELEAFFRGAGWNVIKVVWGREWDALLHADKDGALVNLMNTTPDG
MSMEG_4323|M.smegmatis_MC2_155 NGKIIQELESFFRGAGWNVIKVVWGREWDVLLHADRDGALVNLMNSTPDG
Mflv_2781|M.gilvum_PYR-GCK NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDG
Mvan_3752|M.vanbaalenii_PYR-1 NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDG
Rv2241|M.tuberculosis_H37Rv NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDG
Mb2265|M.bovis_AF2122/97 NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDRALVNLMNTTPDG
MLBr_01651|M.leprae_Br4923 NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVDLMNATPDG
MAV_2196|M.avium_104 NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDG
MMAR_3334|M.marinum_M NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNSTPDG
MUL_1308|M.ulcerans_Agy99 NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNSTPDG
*********:*******************.*****:* ***:***:*.**
MAB_1884c|M.abscessus_ATCC_199 DYQTYKANDGAYVREHFFGRDPRTKELVKDLTDAQVWNLKRGGHDYRKVY
TH_1339|M.thermoresistible__bu DYQTYKANDGAYVREHFFGRDPRTKALVQNMTDQEIWNLKRGGHDYRKVY
MSMEG_4323|M.smegmatis_MC2_155 DYQTYKANDGAYVRDHFFGRDPRTKALVADMSDQEIWNLKRGGHDYRKVY
Mflv_2781|M.gilvum_PYR-GCK DYQTYKANDGSYVRDHFFGRDPRTKALVEPMTDAEIWNLKRGGHDYRKVY
Mvan_3752|M.vanbaalenii_PYR-1 DYQTYKANDGAYVRDHFFGRDPRTKALVENMTDREIWNLKRGGHDYRKVY
Rv2241|M.tuberculosis_H37Rv DYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNLKRGGHDYRKVY
Mb2265|M.bovis_AF2122/97 DYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNLKRGGHDYRKVY
MLBr_01651|M.leprae_Br4923 DYQTYKANDGRFVRDHFFGRDPRTKALVEHMSDQEIWNLKRGGHDYRKVY
MAV_2196|M.avium_104 DYQTYKANDGAYVRDHFFGRDPRTKALVENMTDAEIWNLKRGGHDYRKVY
MMAR_3334|M.marinum_M DYQTYKANDGAYVRDHFFGRDPRTKALVANMSDQEIWNLKRGGHDYRKVY
MUL_1308|M.ulcerans_Agy99 DYQTYKANDGAYVRDHFFGRDPRTKALVANMSDQEIWNLKRGGHDYRKVY
********** :**:********** ** ::* ::**************
MAB_1884c|M.abscessus_ATCC_199 AAYRAATEHKGQPTVILAKTIKGYTLGKHFEGRNATHQMKKLTLDDLKDF
TH_1339|M.thermoresistible__bu AAYRAAVEHKGQPTVILAKTIKGYSLGANFQGRNATHQMKKLALDDLKHF
MSMEG_4323|M.smegmatis_MC2_155 AAYRAAMEHKGQPTVILAKTIKGYTLGQHFEGRNATHQMKKLALEDLKNF
Mflv_2781|M.gilvum_PYR-GCK AAYHAAMEHKGQPTVILAKTIKGYTLGKHFEGRNATHQMKKLALQDLKDF
Mvan_3752|M.vanbaalenii_PYR-1 AAYHAALEHKGQPTVILAKTIKGYTLGKHFEGRNATHQMKKLALQDLKDF
Rv2241|M.tuberculosis_H37Rv AAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKEF
Mb2265|M.bovis_AF2122/97 AAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKEF
MLBr_01651|M.leprae_Br4923 ASYRAAVDHKGQPTVILAKTIKGYALGKHFESRNATHQMKKLTLEDLKEF
MAV_2196|M.avium_104 AAYRAAVDHKGQPTVILAKTIKGYSLGAHFQGRNATHQMKKLALEDLKHF
MMAR_3334|M.marinum_M AAYRAAVDHKGQPTVILAKTIKGYSLGAHFQGRNATHQMKKLALADLKRF
MUL_1308|M.ulcerans_Agy99 AAYRAAVDHKGQPTVILAKTIKGYSLGAHFQGRNATHQMKKLALADLKRF
*:*:** :****************:** :*:.**********:* *** *
MAB_1884c|M.abscessus_ATCC_199 RDKQRIPISDAQLEENPYLPPYYHPGPEAPEIRYMLDRRRALGGFVPSRR
TH_1339|M.thermoresistible__bu RDAMRIPISDEQLEENPYLPPYYHPGPEAPEIRYMLERRRALGGFVPERR
MSMEG_4323|M.smegmatis_MC2_155 RDVTRVPVSDAQLEEDPYLPPYYHPGPEAPEIRYLLERRRALGGFVPSRR
Mflv_2781|M.gilvum_PYR-GCK RDVQRIPVSDSQLEENPYLPPYYHPGPEAPEIRYMLDRRRALGGFLPERR
Mvan_3752|M.vanbaalenii_PYR-1 RDAQRIPVSDEQLEADPYLPPYYHPGPEAPEIRYMLDRRRALGGFLPERR
Rv2241|M.tuberculosis_H37Rv RDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERR
Mb2265|M.bovis_AF2122/97 RDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERR
MLBr_01651|M.leprae_Br4923 RDTQRIPISDTELEENPYLPPYYHPGPDSPEIRYLLDRRRALGGFLPERR
MAV_2196|M.avium_104 RDAMRIPISDAQLDENPYLPPYYHPGSDAPEIRYMLDRRRTLGGFLPERR
MMAR_3334|M.marinum_M RDSMRIPVSDAQLDEDPYLPPYYHPGSDAPEIRYMLDRRRTLGGFLPERP
MUL_1308|M.ulcerans_Agy99 RDSMRIPVSDAQLDEDPYLPPYYHPGSDAPEIRYMLDRRRTLGGFLPERP
** *:*:** :*: :********** ::*****:*:***:****:*.*
MAB_1884c|M.abscessus_ATCC_199 TTSRPLTLPGSETYASIKKGSGKQEVATTMALVRTFKELLRDKNIGNRIV
TH_1339|M.thermoresistible__bu TTSKALRIPGSDIFRSVRKGSGNQEVATTMATVRTFREVLRDKELGWRIV
MSMEG_4323|M.smegmatis_MC2_155 TKSKPLALPGSDTYKALKKGSGSQAVATTMATVRTFKELLRDKNIGPRIV
Mflv_2781|M.gilvum_PYR-GCK TKTKALTLPGRDTYKALKKGSGKQEVATTMATVRTFKELLRDKNIGWRIV
Mvan_3752|M.vanbaalenii_PYR-1 TKSRALTLPGRDVYKALKKGSGKQEVATTMATVRTFKELLRDKNIGSRIV
Rv2241|M.tuberculosis_H37Rv TKSKALTLPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIV
Mb2265|M.bovis_AF2122/97 TKSKALTLPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIV
MLBr_01651|M.leprae_Br4923 TKSGALTLPGRDTYAALKTGSGQQEVATTMAIVRTFKEVLRHKEVGPRIV
MAV_2196|M.avium_104 TKAKALRLPGRDIYAALKKGSGTQEVATTMATVRTFKEVLRDKEIGPRIV
MMAR_3334|M.marinum_M TKAKTLTLPGPDAYKVLKKGSGQQEVATTMALVRTFKELLRDKNIGNRIV
MUL_1308|M.ulcerans_Agy99 TKAKTLTLPGPDAYKVLKKGSGQQEVATTMALVRTFKELLRDKNIGNRIV
*.: .* :** : : ::.*** * ****** ****:*:**.*::* ***
MAB_1884c|M.abscessus_ATCC_199 PIIPDEARTFGMDSWFPSLKIYNRNGQLYTSVDAELMLAYKESAQGQILH
TH_1339|M.thermoresistible__bu PIIPDEARTFGMDSWFPSLKIYNPNGQLYTSVDADLMLAYKESEAGQILH
MSMEG_4323|M.smegmatis_MC2_155 PIIPDEARTFGMDSWFPSLKIYNRNGQLYTSVDSELMLAYKESEVGQILH
Mflv_2781|M.gilvum_PYR-GCK PIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDAELMLAYKESEVGQILH
Mvan_3752|M.vanbaalenii_PYR-1 PIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDAELMLAYKESEIGQILH
Rv2241|M.tuberculosis_H37Rv PIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDADLMLAYKESEVGQILH
Mb2265|M.bovis_AF2122/97 PIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDADLMLAYKESEVGQILH
MLBr_01651|M.leprae_Br4923 PIIPDEARTFGMDSWFPSLKIYNHNGQLYTAVDAQLMLAYKESEVGQILH
MAV_2196|M.avium_104 PIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDAELMLAYKESEVGQILH
MMAR_3334|M.marinum_M PIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDAELMLAYKESHVGQILH
MUL_1308|M.ulcerans_Agy99 PIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDAELMLAYKESHVGQILH
*********************** ******:**::******** *****
MAB_1884c|M.abscessus_ATCC_199 EGINEAGSTASFTAVGTAYSTHDEPMIPLYIFYSMFGFQRTGDGLWAAAD
TH_1339|M.thermoresistible__bu EGINEAGSSASFIAAGTSYATHNEPMIPIYIFYSMFGFQRTGDNLWAAGD
MSMEG_4323|M.smegmatis_MC2_155 EGINEAGSTSSFTAVGTSYSTHDEPMIPIYIFYSMFGFQRTGDGLWAAAD
Mflv_2781|M.gilvum_PYR-GCK EGINEAGSTASFTAVGTSYATHNEPMIPIYIFYSMFGFQRTGDGLWAAAD
Mvan_3752|M.vanbaalenii_PYR-1 EGINEAGSTASFTAVGTSYATHNEPMIPIYIFYSMFGFQRTGDGLWAAAD
Rv2241|M.tuberculosis_H37Rv EGINEAGSVGSFIAAGTSYATHNEPMIPIYIFYSMFGFQRTGDSFWAAAD
Mb2265|M.bovis_AF2122/97 EGINEAGSVGSFIAAGTSYATHNEPMIPIYIFYSMFGFQRTGDSFWAAAD
MLBr_01651|M.leprae_Br4923 EGIDEAGSVGSFIAAGTSYSTHNEPMIPIYIFYSMFGFQRTGDGLWAAAD
MAV_2196|M.avium_104 EGINEAGSVGSFIAAGTSYATHNEPMIPIYIFYSMFGFQRTGDGLWAAAD
MMAR_3334|M.marinum_M EGINEAGSVGSFTAAGTSYATHNEPMIPIYIFYSMFGFQRTGDSFWAAAD
MUL_1308|M.ulcerans_Agy99 EGINEAGSVGSFTAAGTSYATHNEPMIPIYIFYSMFGFQRTGDSFWAAAD
***:**** .** *.**:*:**:*****:**************.:***.*
MAB_1884c|M.abscessus_ATCC_199 QMARGFVLGATAGRTTLTGEGLQHADGHSLLLASTNPAVVAYDPAFAYEI
TH_1339|M.thermoresistible__bu QMARGFLLGATAGRTTLVGEGLQHADGHSLLLASTNPAVVAYDPAFAYEI
MSMEG_4323|M.smegmatis_MC2_155 QMARGFVLGATAGRTTLTGEGLQHADGHSLLLASTNPAAVTYDPAFAYEI
Mflv_2781|M.gilvum_PYR-GCK QMARGFVLGATAGRTTLVGEGLQHADGHSLLLAATNPAVVSYDPAFAFEI
Mvan_3752|M.vanbaalenii_PYR-1 QMARGFVLGATAGRTTLVGEGLQHADGHSLLLASTNPAVVAYDPAFAYEI
Rv2241|M.tuberculosis_H37Rv QMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVAYDPAFAYEI
Mb2265|M.bovis_AF2122/97 QMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVAYDPAFAYEI
MLBr_01651|M.leprae_Br4923 QMARGFLLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVTYDPAFAYEI
MAV_2196|M.avium_104 QMTRGFLLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVAYDPAFAYEI
MMAR_3334|M.marinum_M QMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVSYDPAFAYEL
MUL_1308|M.ulcerans_Agy99 QMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVSYDPAFAYEL
**:***:**********.***************:****.*:******:*:
MAB_1884c|M.abscessus_ATCC_199 AHIVEHGLQRMYGENSENVYFYITLYNEPYVQPAEPENVDTEGILRGIYK
TH_1339|M.thermoresistible__bu AHIVESGLHRMYGENPENVFFYLTIYNEPYRQPAEPEDLDVEGLLRGIYR
MSMEG_4323|M.smegmatis_MC2_155 AHIIESGLQRMYGEDPENVFFYLTIYNEPYQQPAEPENLDVEALLKGLYL
Mflv_2781|M.gilvum_PYR-GCK AYIIESGLQRMYGDNPENVYFYMTIYNEPYVQPAEPEGIDVEGLLRGMYR
Mvan_3752|M.vanbaalenii_PYR-1 AYIIESGLHRMYGENPENVYFYMTIYNEPYVQPAEPDGLDVEGLLRGMYR
Rv2241|M.tuberculosis_H37Rv AYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIYR
Mb2265|M.bovis_AF2122/97 AYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIYR
MLBr_01651|M.leprae_Br4923 AYIVESGLTRMFGEDPENVFFYITVYNEPYPQPPEPENFDPDGVLRGMYR
MAV_2196|M.avium_104 AYIVESGLARMFGENPEDVYFYITVYNEPYVQPPEPENFDPEGLLRGLYR
MMAR_3334|M.marinum_M AYIIENGLSRMFGENPENIYFYITVYNEPYVQPAEPENFDPEGVLRGMYR
MUL_1308|M.ulcerans_Agy99 AYIIENGLSRMFGENPENIYFYITVYNEPYVQPAEPENFDPEGVLRGMYR
*:*:* ** ** *::.*:::**:*:***** **.**:..* :.:*:*:*
MAB_1884c|M.abscessus_ATCC_199 FRAAPEARTHRANILASGVSVPDALRAADLLAEQWDVAADVWSVTSWGEL
TH_1339|M.thermoresistible__bu YRRAPQKRTHTAQILASGVAMPEALRAADLLAEDWDVAADVWSVTSWGEL
MSMEG_4323|M.smegmatis_MC2_155 YRPAPEKRAKSAQILASGVAMPEALRAADLLASDWDVAADVWSVTSWGEL
Mflv_2781|M.gilvum_PYR-GCK YQAAPQKKSNSAQILVSGVSMPSALKAAEMLAEEWDVSADVWSVTSWGEL
Mvan_3752|M.vanbaalenii_PYR-1 YQAAPEKRTNAAQILVSGVGMPSALKAAELLAQEWDVAADVWSVTSWGEL
Rv2241|M.tuberculosis_H37Rv YHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGEL
Mb2265|M.bovis_AF2122/97 YHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGEL
MLBr_01651|M.leprae_Br4923 YYTAKEQRSNKAHILASGVSMPAALTAAEMLSTQWDVAADVWSVTSWGEL
MAV_2196|M.avium_104 YHVATEQRANKAQILASGVAMPSALSAAKMLADEWDVAADVWSVTSWGEL
MMAR_3334|M.marinum_M YRAATKQCAHKAQLLASGVSMPDALKAAQMLADEWDVATDVWSVTSWSEL
MUL_1308|M.ulcerans_Agy99 YRAATKQCAHKAQLLASGVSMPDALKAAQMLADEWDVATDVWSVTSWSEL
: * : :: *::*.***.:* ** **.:*: :***::********.**
MAB_1884c|M.abscessus_ATCC_199 NRDGLAIDHQALRHPDRPKGVPYVTKALEGAQ----GPKVAVSDWMHAVP
TH_1339|M.thermoresistible__bu NRDGVTIEKQRLRHPDQPADTPYVTRALADAS----GPVVAVSDWMRAVP
MSMEG_4323|M.smegmatis_MC2_155 NREGVAIEKHRLRHPDEPAGTPHVTSALADAA----GPVIAVSDWMRAVP
Mflv_2781|M.gilvum_PYR-GCK NREGVAIEKERLRHPDREVATPYVTEALAGAE----GPVVAVSDWMRAVP
Mvan_3752|M.vanbaalenii_PYR-1 NRDGVAIEREKLRHPELPAATPYVTKMLAEAA----GPVVAVSDWMRAVP
Rv2241|M.tuberculosis_H37Rv NRDGVAIETEKLRHPDRPAGVPYVTRALENAR----GPVIAVSDWMRAVP
Mb2265|M.bovis_AF2122/97 NRDGVAIETEKLRHPDRPAGVPYVTRALENAR----GPVIAVSDWMRAVP
MLBr_01651|M.leprae_Br4923 NRDGMSIETARLRYPDQPTSVPYVTQVLSEARSDNAGPVIAVSDWMRAVP
MAV_2196|M.avium_104 NRDGVAIDRARLRHPDRPAGVPYVTQALSDAS----GPVVAVSDWMRAVP
MMAR_3334|M.marinum_M NRDGVSVERHRLRHPGEPAGVAYVTTALEGTS----GPVVAVSDWMRAVP
MUL_1308|M.ulcerans_Agy99 NRDGVSVERHRLRHPGEPAGVAYVTTALEGTS----GPVVAVSDWMRAVP
**:*:::: **:* ..:** * : ** :******:***
MAB_1884c|M.abscessus_ATCC_199 EQIRPWVPGMYRTLGADGFGISDTRPAARRFFNTDAESVVVAVLEALADE
TH_1339|M.thermoresistible__bu EQIRAWVPGTYITLGTDGFGFSDTRPAARRYFNTDAESVAVAVLEGLARD
MSMEG_4323|M.smegmatis_MC2_155 EQIRPWVPGTYVTLGTDGFGFSDTRPAARRYFNTDAESVVVAVLQGLARD
Mflv_2781|M.gilvum_PYR-GCK EQIRPWVPGTYVTLGTDGFGFSDTRPAARRYYNTDAESIVVAVLEGLARD
Mvan_3752|M.vanbaalenii_PYR-1 EQIRPWVPGTYITLGTDGFGFSDTRPAARRYYNTDAESVVVAVLEGLARD
Rv2241|M.tuberculosis_H37Rv EQIRPWVPGTYLTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALAGD
Mb2265|M.bovis_AF2122/97 EQIRPWVPGTYLTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALAGD
MLBr_01651|M.leprae_Br4923 EQIRPWVPGTYVTLGTDGFGFSDTRTATRRYFNTDAESQVVAVLEALARD
MAV_2196|M.avium_104 EQIRPWVPGTYVTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALARD
MMAR_3334|M.marinum_M EQIRPWVPGTYVTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALARD
MUL_1308|M.ulcerans_Agy99 EQIRPWVPGTYVTLGTDGFGFSNTRPAARRYFNTDAESQVVAVLEALARD
****.**** * ***:****:*:**.*:**::****** .****:.** :
MAB_1884c|M.abscessus_ATCC_199 GSVDRQVAVTAAAQYKIDDVSAADVSYKDTGSA---
TH_1339|M.thermoresistible__bu GNLDRSVAVEAARRYRIDDVMAAPEQTSDPGVA---
MSMEG_4323|M.smegmatis_MC2_155 GEIDASVAAQAAEQYRIDDVSAAGVSYADTGSA---
Mflv_2781|M.gilvum_PYR-GCK GNIDISAAVDAARRYEIDDVMAAPEQTSDPGVA---
Mvan_3752|M.vanbaalenii_PYR-1 GNIDISVAVEAAKKYEIDDVMAAPEQTSDPGVA---
Rv2241|M.tuberculosis_H37Rv GEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPGA--
Mb2265|M.bovis_AF2122/97 GEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPGA--
MLBr_01651|M.leprae_Br4923 GEIDPSVPVAATRQYQIDDVQAAPEQTSDPGPGVQN
MAV_2196|M.avium_104 GEIDPSVPVAAARQYRIDDVLAAPEQTSDPGVA---
MMAR_3334|M.marinum_M GEIDESVAVTAARQYRIDDVQAAPKQTSDSGVA---
MUL_1308|M.ulcerans_Agy99 GEIDESMAVTAARQYRIDDVQAAPKQTSDSGVA---
*.:* . .. *: :*.**** ** . *.* .