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M. leprae Br4923 MLBr_01651 (aceE)

annotation: pyruvate dehydrogenase subunit E1
coordinates: 1989091 - 1991901
length: 936

LTIEFARPDLAKNPSSTNESNSVRVIREGVASYLPDIDPEETAEWLESFDELLKHSGPSRARYLILRLLE
RAGEQRVTIPALTWTDYVNTIPTELEPWFPGDEDIERRYRTWIRWNAAIMVHRAQRPGVGVGGHISTYAS
SAALYEVGFNHFFRGKSHPSGGDQVFIQGHASPGIYARAFLEGRLSADQLDGFRQEHSHPGGGLPSYPHP
RLMPDFWEFPTVSMGLGPLNAIYQARFNRYLHDRGIKDTSDQHVWCFLGDGEMDEPESRGLAHVASLEDL
DNLIFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVDLMNATPDG
DYQTYKANDGRFVRDHFFGRDPRTKALVEHMSDQEIWNLKRGGHDYRKVYASYRAAVDHKGQPTVILAKT
IKGYALGKHFESRNATHQMKKLTLEDLKEFRDTQRIPISDTELEENPYLPPYYHPGPDSPEIRYLLDRRR
ALGGFLPERRTKSGALTLPGRDTYAALKTGSGQQEVATTMAIVRTFKEVLRHKEVGPRIVPIIPDEARTF
GMDSWFPSLKIYNHNGQLYTAVDAQLMLAYKESEVGQILHEGIDEAGSVGSFIAAGTSYSTHNEPMIPIY
IFYSMFGFQRTGDGLWAAADQMARGFLLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVTYDPAFAYEI
AYIVESGLTRMFGEDPENVFFYITVYNEPYPQPPEPENFDPDGVLRGMYRYYTAKEQRSNKAHILASGVS
MPAALTAAEMLSTQWDVAADVWSVTSWGELNRDGMSIETARLRYPDQPTSVPYVTQVLSEARSDNAGPVI
AVSDWMRAVPEQIRPWVPGTYVTLGTDGFGFSDTRTATRRYFNTDAESQVVAVLEALARDGEIDPSVPVA
ATRQYQIDDVQAAPEQTSDPGPGVQN
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_01651aceE-100% (936)pyruvate dehydrogenase subunit E1
M. leprae Br4923MLBr_00583tkt1e-0624.60% (252) transketolase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2265aceE0.089.49% (904) pyruvate dehydrogenase subunit E1
M. gilvum PYR-GCKMflv_2781aceE0.084.32% (931) pyruvate dehydrogenase subunit E1
M. tuberculosis H37RvRv2241aceE0.089.60% (904) pyruvate dehydrogenase subunit E1
M. abscessus ATCC 19977MAB_1884caceE0.080.60% (907) pyruvate dehydrogenase subunit E1
M. marinum MMMAR_3334aceE0.085.71% (931) pyruvate dehydrogenase E1 component AceE
M. avium 104MAV_2196aceE0.088.18% (931) pyruvate dehydrogenase subunit E1
M. smegmatis MC2 155MSMEG_4323aceE0.083.03% (931) pyruvate dehydrogenase subunit E1
M. thermoresistible (build 8)TH_1339aceE0.082.28% (931) Probable pyruvate dehydrogenase E1 component aceE (PYRUVATE
M. ulcerans Agy99MUL_1308aceE0.085.50% (931) pyruvate dehydrogenase subunit E1
M. vanbaalenii PYR-1Mvan_3752aceE0.084.00% (925) pyruvate dehydrogenase subunit E1

CLUSTAL 2.0.9 multiple sequence alignment


MAB_1884c|M.abscessus_ATCC_199      ------------------------MIREGVASYLPDIDPDETGEWLESFD
TH_1339|M.thermoresistible__bu      LTTEFVRQDLAQNSKSTTGHGRVRVIRDGVAAYLPDIDPEETAEWLESFD
MSMEG_4323|M.smegmatis_MC2_155      MTTEFVRQDLAQNSSTAAEPDRVRVIREGVASYLPDIDTEETAEWLESFD
Mflv_2781|M.gilvum_PYR-GCK          MTTEFVRQDLAQNSSSTGEPDRVRVIREGVASYLPDIDPEETGEWLESFD
Mvan_3752|M.vanbaalenii_PYR-1       -----MRQDLAQNSGSTAEPDRVRVIREGVASYLPDIDPEETGEWLESFD
Mb2265|M.bovis_AF2122/97            -----------------------------MASYLPDIDPEETSEWLESFD
Rv2241|M.tuberculosis_H37Rv         -----------------------------MASYLPDIDPEETSEWLESFD
MLBr_01651|M.leprae_Br4923          MTIEFARPDLAKNPSSTNESNSVRVIREGVASYLPDIDPEETAEWLESFD
MAV_2196|M.avium_104                MTTEFVRHDLATNPTGPAEPDRVRVIREGVASYLPDIDPEETSEWLESFD
MMAR_3334|M.marinum_M               MTTEFVRHDLAKTSSSASEPDRVRVIREGVASYLPDIDPEETSEWLESFD
MUL_1308|M.ulcerans_Agy99           MTTEFVRHDLAKTSSSASEPDRVRVIREGVASYLPDIDPEETSEWLESFD
                                                                 :*:******.:**.*******

MAB_1884c|M.abscessus_ATCC_199      GLLARSGPARARYLMLRLLERANAGRVAIPALTSTDYVNTIPTENEPWFP
TH_1339|M.thermoresistible__bu      QLVERSGPARARYLMLRMLERAREQRVAIPALTSTDYVNTIPTENEPWFP
MSMEG_4323|M.smegmatis_MC2_155      ELLERSGPARARYLMLRLLERAGEQRVAIPALTSTDYVNTIPTELEPWFP
Mflv_2781|M.gilvum_PYR-GCK          DLLERSGPARARYLMLRLLERAGEQRVAIPALTSTDYVNTIPTELEPWFP
Mvan_3752|M.vanbaalenii_PYR-1       DLLERSGPARARYLMLRLLERSREKRVAIPALTSTDYVNTIPTELEPWFP
Mb2265|M.bovis_AF2122/97            TLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVNTIPTELEPWFP
Rv2241|M.tuberculosis_H37Rv         TLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVNTIPTELEPWFP
MLBr_01651|M.leprae_Br4923          ELLKHSGPSRARYLILRLLERAGEQRVTIPALTWTDYVNTIPTELEPWFP
MAV_2196|M.avium_104                ELLERSGPSRARYLMLRLLERAGEQRVAIPSLTSTDYVNTIPTELEPWFP
MMAR_3334|M.marinum_M               ALLEHSGPARARYLMLRLLERAGEQRVAIPSLTSTDYVNTIPTELEPWFP
MUL_1308|M.ulcerans_Agy99           ALLEHSGPARARYLMLRLLERAGEQRVAIPSLTSTDYVNTIPTELEPWFP
                                     *: :.**:*****:**:***:   **:**:** ********** *****

MAB_1884c|M.abscessus_ATCC_199      GDEDTERRFRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN
TH_1339|M.thermoresistible__bu      GDEDTERRFRLWIRWNAAIMVHRAQRPGVGVGGHISTYASSATLYEVGFN
MSMEG_4323|M.smegmatis_MC2_155      GDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSATLYEVGFN
Mflv_2781|M.gilvum_PYR-GCK          GDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN
Mvan_3752|M.vanbaalenii_PYR-1       GDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN
Mb2265|M.bovis_AF2122/97            GDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN
Rv2241|M.tuberculosis_H37Rv         GDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN
MLBr_01651|M.leprae_Br4923          GDEDIERRYRTWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN
MAV_2196|M.avium_104                GDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN
MMAR_3334|M.marinum_M               GDEDVERRYRTWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN
MUL_1308|M.ulcerans_Agy99           GDEDVERRYRTWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFN
                                    **** ***:* *******************************:*******

MAB_1884c|M.abscessus_ATCC_199      HFFRGNAHPGGGDQIFIQGHASPGIYARAFLEGRLTTDQLDGFRQEKSHP
TH_1339|M.thermoresistible__bu      HFFRGKAHPGGGDQVFIQGHASPGIYARAFLEGRLTADQLDGFRQEHSHP
MSMEG_4323|M.smegmatis_MC2_155      HFFRGKSHPGGGDHVFIQGHASPGIYARAFLEGRLTTDQLDGFRQEHSHS
Mflv_2781|M.gilvum_PYR-GCK          HFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTTDQLDGFRQEHSHA
Mvan_3752|M.vanbaalenii_PYR-1       HFFRGKSHPGGGDQIFIQGHASPGIYARAYLEGRLSADQLDGFRQEHSHP
Mb2265|M.bovis_AF2122/97            HFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHV
Rv2241|M.tuberculosis_H37Rv         HFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHV
MLBr_01651|M.leprae_Br4923          HFFRGKSHPSGGDQVFIQGHASPGIYARAFLEGRLSADQLDGFRQEHSHP
MAV_2196|M.avium_104                HFFRGKSHPGGGDQIFIQGHASPGIYARAFLEGRLTADQLDGFRQEHSHA
MMAR_3334|M.marinum_M               HFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLSADQLDGFRQEHSHP
MUL_1308|M.ulcerans_Agy99           HFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLSADQLDGFRQEHSHP
                                    *****::**.***::**************:*****:::********:** 

MAB_1884c|M.abscessus_ATCC_199      GGGLPSYPHPRLMPDFWQFPTVSMGLGPMNAIMQARFNHYLRDRGIKDTS
TH_1339|M.thermoresistible__bu      GGGLPSYPHPRLMPDFWEFPTVSMGLGPINAIFQARFNRYLHNRGIKDTS
MSMEG_4323|M.smegmatis_MC2_155      GGGLPSYPHPRLMPDFWEFPTVSMGLGPMNAIYQARFNHYLHDRGIKDTS
Mflv_2781|M.gilvum_PYR-GCK          GGGLPSYPHPRLMPDFWEFPTVSMGLGPMNAIYQARFNHYLHDRDIKDTS
Mvan_3752|M.vanbaalenii_PYR-1       GGGLPSYPHPRLMPDFWEFPTVSMGLGPMNAIYQARFNHYLHDRGIKDTS
Mb2265|M.bovis_AF2122/97            GGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTS
Rv2241|M.tuberculosis_H37Rv         GGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTS
MLBr_01651|M.leprae_Br4923          GGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNRYLHDRGIKDTS
MAV_2196|M.avium_104                GGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTS
MMAR_3334|M.marinum_M               GGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTS
MUL_1308|M.ulcerans_Agy99           GGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTS
                                    *****************:**********:*** *****:**::*.*****

MAB_1884c|M.abscessus_ATCC_199      DQRVWAFLGDGEMDEPESRGLAHIAATEGLDNLTFVVNCNLQRLDGPVRG
TH_1339|M.thermoresistible__bu      GQHVWCFLGDGEMDEPESRGAAHVAALEGLDNLTFVVNCNLQRLDGPVRG
MSMEG_4323|M.smegmatis_MC2_155      DQHVWAFLGDGEMDEPESRGLIQVAANEALDNLTFVINCNLQRLDGPVRG
Mflv_2781|M.gilvum_PYR-GCK          KQHVWAFLGDGEMDEPESRGLIQVAANEGLDNLTFVVNCNLQRLDGPVRG
Mvan_3752|M.vanbaalenii_PYR-1       KQHVWAFLGDGEMDEPESRGLIQVAANEALDNLTFVVNCNLQRLDGPVRG
Mb2265|M.bovis_AF2122/97            DQHVWCFLGDGEMDEPESRGLAHVGALEGLDNLTFVINCNLQRLDGPVRG
Rv2241|M.tuberculosis_H37Rv         DQHVWCFLGDGEMDEPESRGLAHVGALEGLDNLTFVINCNLQRLDGPVRG
MLBr_01651|M.leprae_Br4923          DQHVWCFLGDGEMDEPESRGLAHVASLEDLDNLIFVINCNLQRLDGPVRG
MAV_2196|M.avium_104                DQHVWCFLGDGEMDEPESRGLIQVAANEALDNLTFVINCNLQRLDGPVRG
MMAR_3334|M.marinum_M               DQHVWCFLGDGEMDEPESRGLAHMGALEGLDNLTFVINCNLQRLDGPVRG
MUL_1308|M.ulcerans_Agy99           DQHVWCFLGDGEMDEPESRGLAHMGALEGLDNLTFVINCNLQRLDGPVRG
                                     *:**.**************  ::.: * **** **:*************

MAB_1884c|M.abscessus_ATCC_199      NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTADG
TH_1339|M.thermoresistible__bu      NGKIIQELEAFFRGAGWNVIKVVWGREWDALLHADKDGALVNLMNTTPDG
MSMEG_4323|M.smegmatis_MC2_155      NGKIIQELESFFRGAGWNVIKVVWGREWDVLLHADRDGALVNLMNSTPDG
Mflv_2781|M.gilvum_PYR-GCK          NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDG
Mvan_3752|M.vanbaalenii_PYR-1       NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDG
Mb2265|M.bovis_AF2122/97            NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDRALVNLMNTTPDG
Rv2241|M.tuberculosis_H37Rv         NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDG
MLBr_01651|M.leprae_Br4923          NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVDLMNATPDG
MAV_2196|M.avium_104                NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDG
MMAR_3334|M.marinum_M               NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNSTPDG
MUL_1308|M.ulcerans_Agy99           NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNSTPDG
                                    *********:*******************.*****:* ***:***:*.**

MAB_1884c|M.abscessus_ATCC_199      DYQTYKANDGAYVREHFFGRDPRTKELVKDLTDAQVWNLKRGGHDYRKVY
TH_1339|M.thermoresistible__bu      DYQTYKANDGAYVREHFFGRDPRTKALVQNMTDQEIWNLKRGGHDYRKVY
MSMEG_4323|M.smegmatis_MC2_155      DYQTYKANDGAYVRDHFFGRDPRTKALVADMSDQEIWNLKRGGHDYRKVY
Mflv_2781|M.gilvum_PYR-GCK          DYQTYKANDGSYVRDHFFGRDPRTKALVEPMTDAEIWNLKRGGHDYRKVY
Mvan_3752|M.vanbaalenii_PYR-1       DYQTYKANDGAYVRDHFFGRDPRTKALVENMTDREIWNLKRGGHDYRKVY
Mb2265|M.bovis_AF2122/97            DYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNLKRGGHDYRKVY
Rv2241|M.tuberculosis_H37Rv         DYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNLKRGGHDYRKVY
MLBr_01651|M.leprae_Br4923          DYQTYKANDGRFVRDHFFGRDPRTKALVEHMSDQEIWNLKRGGHDYRKVY
MAV_2196|M.avium_104                DYQTYKANDGAYVRDHFFGRDPRTKALVENMTDAEIWNLKRGGHDYRKVY
MMAR_3334|M.marinum_M               DYQTYKANDGAYVRDHFFGRDPRTKALVANMSDQEIWNLKRGGHDYRKVY
MUL_1308|M.ulcerans_Agy99           DYQTYKANDGAYVRDHFFGRDPRTKALVANMSDQEIWNLKRGGHDYRKVY
                                    ********** :**:********** **  ::* ::**************

MAB_1884c|M.abscessus_ATCC_199      AAYRAATEHKGQPTVILAKTIKGYTLGKHFEGRNATHQMKKLTLDDLKDF
TH_1339|M.thermoresistible__bu      AAYRAAVEHKGQPTVILAKTIKGYSLGANFQGRNATHQMKKLALDDLKHF
MSMEG_4323|M.smegmatis_MC2_155      AAYRAAMEHKGQPTVILAKTIKGYTLGQHFEGRNATHQMKKLALEDLKNF
Mflv_2781|M.gilvum_PYR-GCK          AAYHAAMEHKGQPTVILAKTIKGYTLGKHFEGRNATHQMKKLALQDLKDF
Mvan_3752|M.vanbaalenii_PYR-1       AAYHAALEHKGQPTVILAKTIKGYTLGKHFEGRNATHQMKKLALQDLKDF
Mb2265|M.bovis_AF2122/97            AAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKEF
Rv2241|M.tuberculosis_H37Rv         AAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKEF
MLBr_01651|M.leprae_Br4923          ASYRAAVDHKGQPTVILAKTIKGYALGKHFESRNATHQMKKLTLEDLKEF
MAV_2196|M.avium_104                AAYRAAVDHKGQPTVILAKTIKGYSLGAHFQGRNATHQMKKLALEDLKHF
MMAR_3334|M.marinum_M               AAYRAAVDHKGQPTVILAKTIKGYSLGAHFQGRNATHQMKKLALADLKRF
MUL_1308|M.ulcerans_Agy99           AAYRAAVDHKGQPTVILAKTIKGYSLGAHFQGRNATHQMKKLALADLKRF
                                    *:*:** :****************:** :*:.**********:* *** *

MAB_1884c|M.abscessus_ATCC_199      RDKQRIPISDAQLEENPYLPPYYHPGPEAPEIRYMLDRRRALGGFVPSRR
TH_1339|M.thermoresistible__bu      RDAMRIPISDEQLEENPYLPPYYHPGPEAPEIRYMLERRRALGGFVPERR
MSMEG_4323|M.smegmatis_MC2_155      RDVTRVPVSDAQLEEDPYLPPYYHPGPEAPEIRYLLERRRALGGFVPSRR
Mflv_2781|M.gilvum_PYR-GCK          RDVQRIPVSDSQLEENPYLPPYYHPGPEAPEIRYMLDRRRALGGFLPERR
Mvan_3752|M.vanbaalenii_PYR-1       RDAQRIPVSDEQLEADPYLPPYYHPGPEAPEIRYMLDRRRALGGFLPERR
Mb2265|M.bovis_AF2122/97            RDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERR
Rv2241|M.tuberculosis_H37Rv         RDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERR
MLBr_01651|M.leprae_Br4923          RDTQRIPISDTELEENPYLPPYYHPGPDSPEIRYLLDRRRALGGFLPERR
MAV_2196|M.avium_104                RDAMRIPISDAQLDENPYLPPYYHPGSDAPEIRYMLDRRRTLGGFLPERR
MMAR_3334|M.marinum_M               RDSMRIPVSDAQLDEDPYLPPYYHPGSDAPEIRYMLDRRRTLGGFLPERP
MUL_1308|M.ulcerans_Agy99           RDSMRIPVSDAQLDEDPYLPPYYHPGSDAPEIRYMLDRRRTLGGFLPERP
                                    **  *:*:** :*: :********** ::*****:*:***:****:*.* 

MAB_1884c|M.abscessus_ATCC_199      TTSRPLTLPGSETYASIKKGSGKQEVATTMALVRTFKELLRDKNIGNRIV
TH_1339|M.thermoresistible__bu      TTSKALRIPGSDIFRSVRKGSGNQEVATTMATVRTFREVLRDKELGWRIV
MSMEG_4323|M.smegmatis_MC2_155      TKSKPLALPGSDTYKALKKGSGSQAVATTMATVRTFKELLRDKNIGPRIV
Mflv_2781|M.gilvum_PYR-GCK          TKTKALTLPGRDTYKALKKGSGKQEVATTMATVRTFKELLRDKNIGWRIV
Mvan_3752|M.vanbaalenii_PYR-1       TKSRALTLPGRDVYKALKKGSGKQEVATTMATVRTFKELLRDKNIGSRIV
Mb2265|M.bovis_AF2122/97            TKSKALTLPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIV
Rv2241|M.tuberculosis_H37Rv         TKSKALTLPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIV
MLBr_01651|M.leprae_Br4923          TKSGALTLPGRDTYAALKTGSGQQEVATTMAIVRTFKEVLRHKEVGPRIV
MAV_2196|M.avium_104                TKAKALRLPGRDIYAALKKGSGTQEVATTMATVRTFKEVLRDKEIGPRIV
MMAR_3334|M.marinum_M               TKAKTLTLPGPDAYKVLKKGSGQQEVATTMALVRTFKELLRDKNIGNRIV
MUL_1308|M.ulcerans_Agy99           TKAKTLTLPGPDAYKVLKKGSGQQEVATTMALVRTFKELLRDKNIGNRIV
                                    *.: .* :** : :  ::.*** * ****** ****:*:**.*::* ***

MAB_1884c|M.abscessus_ATCC_199      PIIPDEARTFGMDSWFPSLKIYNRNGQLYTSVDAELMLAYKESAQGQILH
TH_1339|M.thermoresistible__bu      PIIPDEARTFGMDSWFPSLKIYNPNGQLYTSVDADLMLAYKESEAGQILH
MSMEG_4323|M.smegmatis_MC2_155      PIIPDEARTFGMDSWFPSLKIYNRNGQLYTSVDSELMLAYKESEVGQILH
Mflv_2781|M.gilvum_PYR-GCK          PIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDAELMLAYKESEVGQILH
Mvan_3752|M.vanbaalenii_PYR-1       PIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDAELMLAYKESEIGQILH
Mb2265|M.bovis_AF2122/97            PIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDADLMLAYKESEVGQILH
Rv2241|M.tuberculosis_H37Rv         PIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDADLMLAYKESEVGQILH
MLBr_01651|M.leprae_Br4923          PIIPDEARTFGMDSWFPSLKIYNHNGQLYTAVDAQLMLAYKESEVGQILH
MAV_2196|M.avium_104                PIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDAELMLAYKESEVGQILH
MMAR_3334|M.marinum_M               PIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDAELMLAYKESHVGQILH
MUL_1308|M.ulcerans_Agy99           PIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDAELMLAYKESHVGQILH
                                    *********************** ******:**::********  *****

MAB_1884c|M.abscessus_ATCC_199      EGINEAGSTASFTAVGTAYSTHDEPMIPLYIFYSMFGFQRTGDGLWAAAD
TH_1339|M.thermoresistible__bu      EGINEAGSSASFIAAGTSYATHNEPMIPIYIFYSMFGFQRTGDNLWAAGD
MSMEG_4323|M.smegmatis_MC2_155      EGINEAGSTSSFTAVGTSYSTHDEPMIPIYIFYSMFGFQRTGDGLWAAAD
Mflv_2781|M.gilvum_PYR-GCK          EGINEAGSTASFTAVGTSYATHNEPMIPIYIFYSMFGFQRTGDGLWAAAD
Mvan_3752|M.vanbaalenii_PYR-1       EGINEAGSTASFTAVGTSYATHNEPMIPIYIFYSMFGFQRTGDGLWAAAD
Mb2265|M.bovis_AF2122/97            EGINEAGSVGSFIAAGTSYATHNEPMIPIYIFYSMFGFQRTGDSFWAAAD
Rv2241|M.tuberculosis_H37Rv         EGINEAGSVGSFIAAGTSYATHNEPMIPIYIFYSMFGFQRTGDSFWAAAD
MLBr_01651|M.leprae_Br4923          EGIDEAGSVGSFIAAGTSYSTHNEPMIPIYIFYSMFGFQRTGDGLWAAAD
MAV_2196|M.avium_104                EGINEAGSVGSFIAAGTSYATHNEPMIPIYIFYSMFGFQRTGDGLWAAAD
MMAR_3334|M.marinum_M               EGINEAGSVGSFTAAGTSYATHNEPMIPIYIFYSMFGFQRTGDSFWAAAD
MUL_1308|M.ulcerans_Agy99           EGINEAGSVGSFTAAGTSYATHNEPMIPIYIFYSMFGFQRTGDSFWAAAD
                                    ***:**** .** *.**:*:**:*****:**************.:***.*

MAB_1884c|M.abscessus_ATCC_199      QMARGFVLGATAGRTTLTGEGLQHADGHSLLLASTNPAVVAYDPAFAYEI
TH_1339|M.thermoresistible__bu      QMARGFLLGATAGRTTLVGEGLQHADGHSLLLASTNPAVVAYDPAFAYEI
MSMEG_4323|M.smegmatis_MC2_155      QMARGFVLGATAGRTTLTGEGLQHADGHSLLLASTNPAAVTYDPAFAYEI
Mflv_2781|M.gilvum_PYR-GCK          QMARGFVLGATAGRTTLVGEGLQHADGHSLLLAATNPAVVSYDPAFAFEI
Mvan_3752|M.vanbaalenii_PYR-1       QMARGFVLGATAGRTTLVGEGLQHADGHSLLLASTNPAVVAYDPAFAYEI
Mb2265|M.bovis_AF2122/97            QMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVAYDPAFAYEI
Rv2241|M.tuberculosis_H37Rv         QMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVAYDPAFAYEI
MLBr_01651|M.leprae_Br4923          QMARGFLLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVTYDPAFAYEI
MAV_2196|M.avium_104                QMTRGFLLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVAYDPAFAYEI
MMAR_3334|M.marinum_M               QMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVSYDPAFAYEL
MUL_1308|M.ulcerans_Agy99           QMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVSYDPAFAYEL
                                    **:***:**********.***************:****.*:******:*:

MAB_1884c|M.abscessus_ATCC_199      AHIVEHGLQRMYGENSENVYFYITLYNEPYVQPAEPENVDTEGILRGIYK
TH_1339|M.thermoresistible__bu      AHIVESGLHRMYGENPENVFFYLTIYNEPYRQPAEPEDLDVEGLLRGIYR
MSMEG_4323|M.smegmatis_MC2_155      AHIIESGLQRMYGEDPENVFFYLTIYNEPYQQPAEPENLDVEALLKGLYL
Mflv_2781|M.gilvum_PYR-GCK          AYIIESGLQRMYGDNPENVYFYMTIYNEPYVQPAEPEGIDVEGLLRGMYR
Mvan_3752|M.vanbaalenii_PYR-1       AYIIESGLHRMYGENPENVYFYMTIYNEPYVQPAEPDGLDVEGLLRGMYR
Mb2265|M.bovis_AF2122/97            AYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIYR
Rv2241|M.tuberculosis_H37Rv         AYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIYR
MLBr_01651|M.leprae_Br4923          AYIVESGLTRMFGEDPENVFFYITVYNEPYPQPPEPENFDPDGVLRGMYR
MAV_2196|M.avium_104                AYIVESGLARMFGENPEDVYFYITVYNEPYVQPPEPENFDPEGLLRGLYR
MMAR_3334|M.marinum_M               AYIIENGLSRMFGENPENIYFYITVYNEPYVQPAEPENFDPEGVLRGMYR
MUL_1308|M.ulcerans_Agy99           AYIIENGLSRMFGENPENIYFYITVYNEPYVQPAEPENFDPEGVLRGMYR
                                    *:*:* ** ** *::.*:::**:*:***** **.**:..* :.:*:*:* 

MAB_1884c|M.abscessus_ATCC_199      FRAAPEARTHRANILASGVSVPDALRAADLLAEQWDVAADVWSVTSWGEL
TH_1339|M.thermoresistible__bu      YRRAPQKRTHTAQILASGVAMPEALRAADLLAEDWDVAADVWSVTSWGEL
MSMEG_4323|M.smegmatis_MC2_155      YRPAPEKRAKSAQILASGVAMPEALRAADLLASDWDVAADVWSVTSWGEL
Mflv_2781|M.gilvum_PYR-GCK          YQAAPQKKSNSAQILVSGVSMPSALKAAEMLAEEWDVSADVWSVTSWGEL
Mvan_3752|M.vanbaalenii_PYR-1       YQAAPEKRTNAAQILVSGVGMPSALKAAELLAQEWDVAADVWSVTSWGEL
Mb2265|M.bovis_AF2122/97            YHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGEL
Rv2241|M.tuberculosis_H37Rv         YHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGEL
MLBr_01651|M.leprae_Br4923          YYTAKEQRSNKAHILASGVSMPAALTAAEMLSTQWDVAADVWSVTSWGEL
MAV_2196|M.avium_104                YHVATEQRANKAQILASGVAMPSALSAAKMLADEWDVAADVWSVTSWGEL
MMAR_3334|M.marinum_M               YRAATKQCAHKAQLLASGVSMPDALKAAQMLADEWDVATDVWSVTSWSEL
MUL_1308|M.ulcerans_Agy99           YRAATKQCAHKAQLLASGVSMPDALKAAQMLADEWDVATDVWSVTSWSEL
                                    :  * :  :: *::*.***.:* ** **.:*: :***::********.**

MAB_1884c|M.abscessus_ATCC_199      NRDGLAIDHQALRHPDRPKGVPYVTKALEGAQ----GPKVAVSDWMHAVP
TH_1339|M.thermoresistible__bu      NRDGVTIEKQRLRHPDQPADTPYVTRALADAS----GPVVAVSDWMRAVP
MSMEG_4323|M.smegmatis_MC2_155      NREGVAIEKHRLRHPDEPAGTPHVTSALADAA----GPVIAVSDWMRAVP
Mflv_2781|M.gilvum_PYR-GCK          NREGVAIEKERLRHPDREVATPYVTEALAGAE----GPVVAVSDWMRAVP
Mvan_3752|M.vanbaalenii_PYR-1       NRDGVAIEREKLRHPELPAATPYVTKMLAEAA----GPVVAVSDWMRAVP
Mb2265|M.bovis_AF2122/97            NRDGVAIETEKLRHPDRPAGVPYVTRALENAR----GPVIAVSDWMRAVP
Rv2241|M.tuberculosis_H37Rv         NRDGVAIETEKLRHPDRPAGVPYVTRALENAR----GPVIAVSDWMRAVP
MLBr_01651|M.leprae_Br4923          NRDGMSIETARLRYPDQPTSVPYVTQVLSEARSDNAGPVIAVSDWMRAVP
MAV_2196|M.avium_104                NRDGVAIDRARLRHPDRPAGVPYVTQALSDAS----GPVVAVSDWMRAVP
MMAR_3334|M.marinum_M               NRDGVSVERHRLRHPGEPAGVAYVTTALEGTS----GPVVAVSDWMRAVP
MUL_1308|M.ulcerans_Agy99           NRDGVSVERHRLRHPGEPAGVAYVTTALEGTS----GPVVAVSDWMRAVP
                                    **:*::::   **:*     ..:**  *  :     ** :******:***

MAB_1884c|M.abscessus_ATCC_199      EQIRPWVPGMYRTLGADGFGISDTRPAARRFFNTDAESVVVAVLEALADE
TH_1339|M.thermoresistible__bu      EQIRAWVPGTYITLGTDGFGFSDTRPAARRYFNTDAESVAVAVLEGLARD
MSMEG_4323|M.smegmatis_MC2_155      EQIRPWVPGTYVTLGTDGFGFSDTRPAARRYFNTDAESVVVAVLQGLARD
Mflv_2781|M.gilvum_PYR-GCK          EQIRPWVPGTYVTLGTDGFGFSDTRPAARRYYNTDAESIVVAVLEGLARD
Mvan_3752|M.vanbaalenii_PYR-1       EQIRPWVPGTYITLGTDGFGFSDTRPAARRYYNTDAESVVVAVLEGLARD
Mb2265|M.bovis_AF2122/97            EQIRPWVPGTYLTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALAGD
Rv2241|M.tuberculosis_H37Rv         EQIRPWVPGTYLTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALAGD
MLBr_01651|M.leprae_Br4923          EQIRPWVPGTYVTLGTDGFGFSDTRTATRRYFNTDAESQVVAVLEALARD
MAV_2196|M.avium_104                EQIRPWVPGTYVTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALARD
MMAR_3334|M.marinum_M               EQIRPWVPGTYVTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALARD
MUL_1308|M.ulcerans_Agy99           EQIRPWVPGTYVTLGTDGFGFSNTRPAARRYFNTDAESQVVAVLEALARD
                                    ****.**** * ***:****:*:**.*:**::****** .****:.** :

MAB_1884c|M.abscessus_ATCC_199      GSVDRQVAVTAAAQYKIDDVSAADVSYKDTGSA---
TH_1339|M.thermoresistible__bu      GNLDRSVAVEAARRYRIDDVMAAPEQTSDPGVA---
MSMEG_4323|M.smegmatis_MC2_155      GEIDASVAAQAAEQYRIDDVSAAGVSYADTGSA---
Mflv_2781|M.gilvum_PYR-GCK          GNIDISAAVDAARRYEIDDVMAAPEQTSDPGVA---
Mvan_3752|M.vanbaalenii_PYR-1       GNIDISVAVEAAKKYEIDDVMAAPEQTSDPGVA---
Mb2265|M.bovis_AF2122/97            GEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPGA--
Rv2241|M.tuberculosis_H37Rv         GEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPGA--
MLBr_01651|M.leprae_Br4923          GEIDPSVPVAATRQYQIDDVQAAPEQTSDPGPGVQN
MAV_2196|M.avium_104                GEIDPSVPVAAARQYRIDDVLAAPEQTSDPGVA---
MMAR_3334|M.marinum_M               GEIDESVAVTAARQYRIDDVQAAPKQTSDSGVA---
MUL_1308|M.ulcerans_Agy99           GEIDESMAVTAARQYRIDDVQAAPKQTSDSGVA---
                                    *.:* . .. *: :*.**** **  .  *.* .