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M. thermoresistible (build 8) TH_1287 (recB)

annotation: PROBABLE EXONUCLEASE V (BETA CHAIN) RECB (EXODEOXYRIBONUCLEASE V BETA CHAIN)(EXODEOXYRIBONUCLEASE V POLYPEPTIDE) (CHI-SPECIFIC ENDONUCLEASE)
coordinates: 2445894 - 2447939
length: 682

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1287recB-100% (682)PROBABLE EXONUCLEASE V (BETA CHAIN) RECB (EXODEOXYRIBONUCLEASE V BETA CHAIN)(EXODEOXYRIBONUCLEASE V POLYPEPTIDE) (CHI-SPECIFIC ENDONUCLEASE)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0647crecBa1e-15364.64% (444) exonuclease V subunit beta
M. gilvum PYR-GCKMflv_5130-0.068.90% (688) exodeoxyribonuclease V, beta subunit
M. tuberculosis H37RvRv0630crecB0.066.23% (684) exonuclease V beta chain
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0399c-0.068.69% (677) exodeoxyribonuclease V, beta subunit (RecB)
M. marinum MMMAR_0957recB0.070.97% (682) exodeoxyribonuclease V (beta chain), RecB
M. avium 104MAV_4543recB0.071.60% (676) exodeoxyribonuclease V, beta subunit
M. smegmatis MC2 155MSMEG_1327recB0.071.26% (675) exodeoxyribonuclease V, beta subunit
M. ulcerans Agy99MUL_0708recB0.070.67% (682) exodeoxyribonuclease V (beta chain), RecB
M. vanbaalenii PYR-1Mvan_1209-0.071.55% (682) exodeoxyribonuclease V, beta subunit

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_5130|M.gilvum_PYR-GCK          MEPFDLLGALPEPRTTTVLEASAGTGKTFALAGLVTRYVAEGVATLDRML
Mvan_1209|M.vanbaalenii_PYR-1       MEPFDLLGPLPAPRTTTVLEASAGTGKTFALAGLVTRYVAEGVATLDQML
TH_1287|M.thermoresistible__bu      --------------------------------------------------
MMAR_0957|M.marinum_M               MRPFDLLGPLPAENSTTVLEASAGTGKTFALAALVTRYVAEGRARLDEML
MUL_0708|M.ulcerans_Agy99           MRPFDLLGPLPAENSTTVLEASAGTGKTFALAALVTRYVAEGRARLDEML
MAV_4543|M.avium_104                MERFDLLGALPAARSTTVLEASAGTGKTFALAGLVTRYLADGAATLDQML
MAB_0399c|M.abscessus_ATCC_199      MKRFDLLGPLPADRSTTVLEASAGTGKTFALAGLVTRYVAEGVATLDQML
MSMEG_1327|M.smegmatis_MC2_155      MKVFDLLGPLPAPNTTTVLEASAGTGKTFALAGLVTRFVAEGVATLDQML
Mb0647c|M.bovis_AF2122/97           MDRFELLGPLPREGTTTVLEASAGTGKTFALAGLVTRYLAETAATLDEML
Rv0630c|M.tuberculosis_H37Rv        MDRFELLGPLPREGTTTVLEASAGTGKTFALAGLVTRYLAETAATLDEML
                                                                                      

Mflv_5130|M.gilvum_PYR-GCK          LITFGRAASQELRERVRSQIVDALRAFDDP-------AAIGDNEVVRHLV
Mvan_1209|M.vanbaalenii_PYR-1       LITFGRAASQELRERVRAQILDALRAFDDP-------SHAADNEIVAHLL
TH_1287|M.thermoresistible__bu      --------------------------------------------------
MMAR_0957|M.marinum_M               LITFGRAASQELRERVRCQMVDAVRVFHDSRNGSDDADPAGDNQLLAHLL
MUL_0708|M.ulcerans_Agy99           LITFGRAASQELRERVRCQMVDAVRVFHDSRNGSDDADPAGDNQLLAHLL
MAV_4543|M.avium_104                LITFGRAASQELRERVRCQIVDAVAAFADP-------SRAGDNELVAYLL
MAB_0399c|M.abscessus_ATCC_199      LITFGRAASQELRDRVRGQIVDALRAFADP--------STARTDLTQYLI
MSMEG_1327|M.smegmatis_MC2_155      LITFGRAASQELRERVRAQIVAALVALDDP--------SRACNDLEEYLV
Mb0647c|M.bovis_AF2122/97           LITFNRAASRELRERVRGQIVEALGALQGD--------APPSGELVEHLL
Rv0630c|M.tuberculosis_H37Rv        LITFNRAASRELRERVRGQIVEAVGALQGD--------APPSGELVEHLL
                                                                                      

Mflv_5130|M.gilvum_PYR-GCK          TGDAEECDARRRRLRDALAGFDAATIATTHQFCQLVLRSLGVAGDTDSGV
Mvan_1209|M.vanbaalenii_PYR-1       TGSHGELTERRQRLRDALAGFDAATIATTHQFCQLVLRSLGVAGDTDSGV
TH_1287|M.thermoresistible__bu      --------------------------------------------------
MMAR_0957|M.marinum_M               DGTAAERDARQQRLRDALAGFDAATIATTHQFCQLVLKSLGVAGDTDAGV
MUL_0708|M.ulcerans_Agy99           DGTAAERDARQQRLRDALAGFDAATIATTHQFCQLVLKSLGVAGDTDAGV
MAV_4543|M.avium_104                DGTEDRLAARRQRLRDGLAGFDAATIATTHQFCQLVLRSLGVAGDTAAGV
MAB_0399c|M.abscessus_ATCC_199      S---AEQDTRQRRLRDALAGFDAATIATTHQFCHIVLKSLGVAGDSDSGV
MSMEG_1327|M.smegmatis_MC2_155      K---TDQQARRRRLRDALAGFDAATIATTHQFCQIVLKSLGVAGDSDAGV
Mb0647c|M.bovis_AF2122/97           RGSDAERAQKRSRLRDALANFDAATIATTHEFCGSVLKSLGVAGDNAADV
Rv0630c|M.tuberculosis_H37Rv        RGSDAERAQKRSRLRDALANFDAATIATTHEFCGSVLKSLGVAGDNAADV
                                                                                      

Mflv_5130|M.gilvum_PYR-GCK          ELVESLDDLVAEIVDDLYLAHFGQDRDEPLLTHESALRLAHAVVGNAHTE
Mvan_1209|M.vanbaalenii_PYR-1       ELVESLDDLVTEIVDDLYLAHFGQDHDEPLLTYADALSLAREVVGNAHTE
TH_1287|M.thermoresistible__bu      --------------------------------------------------
MMAR_0957|M.marinum_M               TLVEDLDELVTEIVDDLYLVHFGRDRDDPPLTYRDALRIARAVVANPSTQ
MUL_0708|M.ulcerans_Agy99           TLVEDLDELVTEIVDDLYLVHFGRDRDDPPLTYRDALRIARAVVANPSTQ
MAV_4543|M.avium_104                TLLDSLDELVAEIVDDLYLAHFGQDHDDPVLHYREALRLARDVVNNPSAQ
MAB_0399c|M.abscessus_ATCC_199      TLVENLDELVCEIVNDRYLTHFGKDRDAPPLSYPAALRLAREVVRNPATQ
MSMEG_1327|M.smegmatis_MC2_155      TLVESLDDLVSEIVDDLYLAHFGGQKDDPELSYPEALKLARVVVGNPATQ
Mb0647c|M.bovis_AF2122/97           ELKESLTDLVTEIVDDRYLANFGRQETDPELTYAEALALALAVVDDPCAQ
Rv0630c|M.tuberculosis_H37Rv        ELKESLTDLVTEIVDDRYLANFGRQETDPELTYAEALALALAVVDDPCAQ
                                                                                      

Mflv_5130|M.gilvum_PYR-GCK          LRPRDPAPGSDAAVRVEFAKAVCAELETRKRKLGILHYDDLLSRLADALE
Mvan_1209|M.vanbaalenii_PYR-1       LRPTDPPPGSDPFVRVQFARAVCAELETRKRRLGILHYDDLLSRLAKALE
TH_1287|M.thermoresistible__bu      --------------------------------------------------
MMAR_0957|M.marinum_M               LRPLDAPPGSRAAICVGFAHHVLEELETRKRRRGILGYDDLLLRLADALA
MUL_0708|M.ulcerans_Agy99           LRPLDAPPGSRAAACVGFAHHVLEGLETRKRRRGILGYDDLLLRLADALA
MAV_4543|M.avium_104                LRPLHPEPGSRAAVSLRFANDVLAELDTRKRRLGVLGYDDLLTRLADALA
MAB_0399c|M.abscessus_ATCC_199      LRPLQPEADSYAFAALGFARDVLEQLEIRKRRRGILGFDDLLTRLADALN
MSMEG_1327|M.smegmatis_MC2_155      LRPRDPDPDSPAAVRLKFARDVLAELEIRKRRRGVLGYDDLLTRLADALE
Mb0647c|M.bovis_AF2122/97           LRPPDPEPGSKAAVRLRFAAEVLEELERRKGRLRAQGFNDLLIRLATALE
Rv0630c|M.tuberculosis_H37Rv        LRPPDPEPGSKAAVRLRFAAEVLEELERRKGRLRAQGFNDLLIRLATALE
                                                                                      

Mflv_5130|M.gilvum_PYR-GCK          APDSPARARMQRRWSIVMVDEFQDTDPVQWQVIDRAFRGHATLILIGDPK
Mvan_1209|M.vanbaalenii_PYR-1       PQDSPARMRMQHRWSIVMVDEFQDTDPVQWQVIDCAFSGHATVILIGDPK
TH_1287|M.thermoresistible__bu      --------------------------------------------------
MMAR_0957|M.marinum_M               SEDSAARARMQQRWPVVMVDEFQDTDAVQWQVIDSAFSGRCTLILIGDPK
MUL_0708|M.ulcerans_Agy99           SEDSAARARMQQRWPVVMVDEFQDTDAVQWQVIDSAFSGRCTLILIGDPK
MAV_4543|M.avium_104                TEHSPARLRMHQRWPIVMVDEFQDTDPVQWQVIDRAFSGRSTLILIGDPK
MAB_0399c|M.abscessus_ATCC_199      ATDSPARVRMHQRWPIVMVDEFQDTDPVQWQVLERAFSGHSTLVLIGDPK
MSMEG_1327|M.smegmatis_MC2_155      PEDSPARVRMQQRWPIVMVDEFQDTDPVQWQVIERAFSGRSTLVLIGDPK
Mb0647c|M.bovis_AF2122/97           AADSPARDRMRERWRIVLVDEFQDTDPMQWRVLERAFSRHSALILIGDPK
Rv0630c|M.tuberculosis_H37Rv        AADSPARDRMRERWRIVLVDEFQDTDPMQWRVLERAFSRHSALILIGDPK
                                                                                      

Mflv_5130|M.gilvum_PYR-GCK          QAIYAFRGGDIVTYLHAAATAGVQRTLGTNYRSDAPLVEGLQAVMRDAQL
Mvan_1209|M.vanbaalenii_PYR-1       QAIYAFRGGDIVTYLHAVSTADRQKTLGTNYRSDGPLVDSLQAVMRDAQL
TH_1287|M.thermoresistible__bu      --------------------------------------------------
MMAR_0957|M.marinum_M               QAIYAFRGGDIVTYLHAAQTAGDKRTLATNWRSDSALVDRLQVVLRGAEL
MUL_0708|M.ulcerans_Agy99           QAIYAFRGGDIVTYLHAAQTAGDKRTLATNWRSDSALVDRLQVVLRGAEL
MAV_4543|M.avium_104                QAIYAFRGGDIVTYLRAAETAGQKKTLDTNWRSDSALLQRLQVVLRGAQL
MAB_0399c|M.abscessus_ATCC_199      QAIYAFRGGDIETYLRAAATAGDKQTLGTNWRSDAALVDRLQVVLRGAQL
MSMEG_1327|M.smegmatis_MC2_155      QAIYAFRGGDIATYLRAAATAGDKQTLGTNWRSDRALVDRLQAVLRGAQL
Mb0647c|M.bovis_AF2122/97           QAIYGFRGGDIHTYLKAAGTADARYTLGVNWRSDRALVESLQTVLRDATL
Rv0630c|M.tuberculosis_H37Rv        QAIYGFRGGDIHTYLKAAGTADARYTLGVNWRSDRALVESLQTVLRDATL
                                                                                      

Mflv_5130|M.gilvum_PYR-GCK          GDPRIVVRRVDAHHREHRLQGAPHNEPFRLRVCTRDQFRVRPDRMIPIDV
Mvan_1209|M.vanbaalenii_PYR-1       GDPRIVAHRVEAHHRDHRLAGAPRNAPFRLRVVTRDQFGTRPDRVVAIDQ
TH_1287|M.thermoresistible__bu      --------------------------------------------------
MMAR_0957|M.marinum_M               GDPAIVVRDVKAHHQGHRLAGAPHNDALRLRVVRRATLGRRGIQNLPIDI
MUL_0708|M.ulcerans_Agy99           GDPAIVVRDVKAHHQGHRLAGAPHNDALRLRVVRRATLGRRGIQNLPIDI
MAV_4543|M.avium_104                GDPAIVVNDVAAHHRGHRLSGAPRNDPFRLRVVSRNTLGRRGIANLPIDE
MAB_0399c|M.abscessus_ATCC_199      GGPDIVVHDVQAHHQGHRLAGAPHNDPFRLRVVSRN---RDGIKVIPIAD
MSMEG_1327|M.smegmatis_MC2_155      GGPDIVVHDVQARHQGHRLVGAPRNDPFRLRVVSRK---PGNTRVIPIDQ
Mb0647c|M.bovis_AF2122/97           GHADIVVRGTDAHHAGHRLASAPRPAPFRLRVVKRHTLGYDGTAHVPIEA
Rv0630c|M.tuberculosis_H37Rv        GHADIVVRGTDAHHAGHRLASAPRPAPFRLRVVKRHTLGYDGTAHVPIEA
                                                                                      

Mflv_5130|M.gilvum_PYR-GCK          LRNHIPKDMAADIAALLNSGATHCGEKLAPGHIAVIVESHRDGHACFAAL
Mvan_1209|M.vanbaalenii_PYR-1       LRRHIPQDMAADIAALLASDATFCDRPVQPGDVAVIVESHRDGHACFDAL
TH_1287|M.thermoresistible__bu      ------------------------------------VETHKDARACYDAL
MMAR_0957|M.marinum_M               LRDHIGRDLASDIGALLASGATFAGRALQANDIAVIVEKHKDARACHRAL
MUL_0708|M.ulcerans_Agy99           LRDHIGRDLASDIGALLASGATFAGRALQANDIAVIVEKHKDARACHRAL
MAV_4543|M.avium_104                LRQHIGADLAADIRALLAAGATFDGKPVRAGDIAVIVERHRDAQACFTAL
MAB_0399c|M.abscessus_ATCC_199      LRRSIGRDLAADIGALLSSGATFDGRPVRARDIAVIVEAHKDARACHTAL
MSMEG_1327|M.smegmatis_MC2_155      LRRHIGRDLAADISALLNSGATWCDQPVQAKDIAVITETHKDARACHAAL
Mb0647c|M.bovis_AF2122/97           LRRHIPDDLAADVAALLASGATFAGRPVVAADIAVIVEHHKDARACRNAL
Rv0630c|M.tuberculosis_H37Rv        LRRHIPDDLAADVAALLASGATFAGRPVVAADIAVIVEHHKDARACRNAL
                                                                        .* *:*.:**  **

Mflv_5130|M.gilvum_PYR-GCK          ADAGIPAVYTGDSDVFSSPAADDWMCLLEAFDQPHRSGLVRAAATTMFFG
Mvan_1209|M.vanbaalenii_PYR-1       TAAGIPAVYTGDSDVFTSPAADDWMCLLEAFDQPHRSGLVRAAATTMFFG
TH_1287|M.thermoresistible__bu      CQAGIPAVYTGDSDVFGSPAAEDWLCLLEAFDQPHRPGMVRAAAATMFFG
MMAR_0957|M.marinum_M               TDAGIHAVYTGDTDVFSSEAADDWLALLEAFDQPHRPGIVRAAAATMFFG
MUL_0708|M.ulcerans_Agy99           TDAGIHAVYTGDTDVFSSEAADDWLALLEAFDQPHRPGIVRAAAATMFFG
MAV_4543|M.avium_104                CDAGVPAVYTGNSDVFTSQAAEDWLCLLEAFDQPHRPGVVRAAAATMFFG
MAB_0399c|M.abscessus_ATCC_199      TEAGIPAVYTGDTDVFSSDAAQDWLYLLEAFDQPHRPGLVRAAAATVFFG
MSMEG_1327|M.smegmatis_MC2_155      LAAGIPAVYTGDSDVFTSEAAEDWLYLLEAFDQPHRPGLVRAAAATMFFG
Mb0647c|M.bovis_AF2122/97           AEAGIPAIYTGDTDVFASQAAKDWLCLLEAFDAPQRSGLVRAAACTMFFG
Rv0630c|M.tuberculosis_H37Rv        AEAGIPAIYTGDTDVFASQAAKDWLCLLEAFDAPQRSGLVRAAACTMFFG
                                      **: *:***::*** * **.**: ****** *:*.*:***** *:***

Mflv_5130|M.gilvum_PYR-GCK          ETAEALALQGDSLTDRIAETLRQWADFARERGVAAVFEAAQLRGMGARVL
Mvan_1209|M.vanbaalenii_PYR-1       ETAESLAAEGDTLTDRVAETLRQWADFARDRGVAAVFEAAQLGGMGERVL
TH_1287|M.thermoresistible__bu      ETAESLAAGGDALTDRVADTLREWAAHARERGVAAIFEAAKLSGMGDRVL
MMAR_0957|M.marinum_M               KTANDLARGGDALTDRVAETLREWADYARERGVAAIFEAAQLGGMSDRVL
MUL_0708|M.ulcerans_Agy99           KTANDLARGGDALTDRVAETLREWADYARERGVAAIFEAAQLGGMSDRVL
MAV_4543|M.avium_104                ETAETLAAGGDALTDRIAQTLREWAGHARERGVAAIFEAAQLLGMGNRVL
MAB_0399c|M.abscessus_ATCC_199      ETAETLAVGGESLTDEIAGTLRTWAARARERGVAAVFEAAQLAGMGKRVL
MSMEG_1327|M.smegmatis_MC2_155      ETAESLAAGGDALTDRVADTLREWAGHARERGVAAIFEAAQLAGMGKRVL
Mb0647c|M.bovis_AF2122/97           ETAESLAAEGDALTDRVAGTLREWADHARHRGVAAVFQAAQLAGMGRRVL
Rv0630c|M.tuberculosis_H37Rv        ETAESLAAEGDALTDRVAGTLREWADHARHRGVAAVFQAAQLAGMGRRVL
                                    :**: **  *::***.:* *** **  **.*****:*:**:* **. ***

Mflv_5130|M.gilvum_PYR-GCK          RWVDGERHMTDLAHLTQLLHDTAHREQYSLPALRDWLRAQRDDRGGLRGT
Mvan_1209|M.vanbaalenii_PYR-1       SWVDGERHMTDLAHLTQVLHGTAHREHFSLPALRDWLRGQRDERS---GA
TH_1287|M.thermoresistible__bu      SWADGERHMTDLAHIAQLLQEAAHRDHLGLPALRDWLRARREETSG--GA
MMAR_0957|M.marinum_M               SWQEGQRHMTDLAHVTQLLQKVSHRERYTLPALRDWLRGQREDRG---GA
MUL_0708|M.ulcerans_Agy99           SWQEGQRHMTDLAHVTQLLQKVSHRERYTLPALRDWLRGQREDRG---GA
MAV_4543|M.avium_104                GWQGGARHMTDLAHLTQLLGEVAHCEHHNLPALRDWLRRQRDERS---GA
MAB_0399c|M.abscessus_ATCC_199      SWRGGERMMTDLAHLTELLQETAHRNGFGPAALRDWLRTQCSEGG---AE
MSMEG_1327|M.smegmatis_MC2_155      SWQGGERLMTDLAHMTQLLQDTAHREGFGLAALRDWLRTQRSERG---GE
Mb0647c|M.bovis_AF2122/97           SQRGGERDLTDLAHIAQLLHEAAHRERLGLPGLRDWLRRQAKAGA---GP
Rv0630c|M.tuberculosis_H37Rv        SQRGGERDLTDLAHIAQLLHEAAHRERLGLPGLRDWLRRQAKAGA---GP
                                        * * :*****::::*  .:* :    ..****** : .  .   . 

Mflv_5130|M.gilvum_PYR-GCK          VERNRRLDSDAAAVQIMTVWVSKGLQFPVVYLPFAFNRNVQPRDVVVFHE
Mvan_1209|M.vanbaalenii_PYR-1       PERNRRLDSDAAAVQIMTVWVSKGLQFPVVYLPFAFNRNIQTRDVVTFHD
TH_1287|M.thermoresistible__bu      TERFRRLDTDAAAVPVMTVFAAKGLQFPVVYLPFAFNRHVRKQELVLYHE
MMAR_0957|M.marinum_M               TERNRRIDSDAAAVQIMTVWVSKGLQYPVVYLPFAFNRNIQERELVLFHD
MUL_0708|M.ulcerans_Agy99           TERNRRIDSDAAAVQIMTVWVSKGLQYPVVYLPFAFNRNIQERELVLFHD
MAV_4543|M.avium_104                PERNRRLDSDAAAVQIMTVFVSKGLQYPIVYLPFAFHRNTTDSDVVLFHD
MAB_0399c|M.abscessus_ATCC_199      AERNRRLDSDAAAVQIMTVWVSKGLQFPVVYLPFSFNRYVPEREYVLYHE
MSMEG_1327|M.smegmatis_MC2_155      SERNRRLDSDAAAVQIMTVWVSKGLQFPVVYLPFAFNRYVPEPDLVLFHD
Mb0647c|M.bovis_AF2122/97           PEHNRRLDSDAAAVQIMTVFVAKGLQFPIVYLPFAFNRNVRSDDILLYHD
Rv0630c|M.tuberculosis_H37Rv        PEHNRRLDSDAAAVQIMTVFVAKGLQFPIVYLPFAFNRNVRSDDILLYHD
                                     *: **:*:***** :***:.:****:*:*****:*:*     : : :*:

Mflv_5130|M.gilvum_PYR-GCK          PATSDGAGDIRCLHIGGESSPDFA-AVAQQARLEAAGDDVRLTYVAMTRA
Mvan_1209|M.vanbaalenii_PYR-1       -------GDIRCLHIGGERSPDHA-AAQQQGRREAAGDDVRLTYVAMTRA
TH_1287|M.thermoresistible__bu      ------DDGTRCLHIGGSDSPDHP-QVAQRGRDEDASDDGRLTYVALTRA
MMAR_0957|M.marinum_M               -------GGTRCLHIGGKDSPDFG-TVERLGAKEAANDDSRLTYVAMTRA
MUL_0708|M.ulcerans_Agy99           -------RGTRCLHIGGKDSPDFG-TVERLGAKEAANDDSRLTYVAMTRA
MAV_4543|M.avium_104                ------EDGTRCLHVGGKDSPDFK-TVERLGRKEDASDDSRLTYVALTRA
MAB_0399c|M.abscessus_ATCC_199      -------DGLRCLHIGGREDPDYS-MADLAGRTEAARDASRLAYVALTRA
MSMEG_1327|M.smegmatis_MC2_155      -------DGQRCLHVGG-ADP----AVARAGRAEAAGDDSRLTYVALTRA
Mb0647c|M.bovis_AF2122/97           -------DGTRCLYIGGKDGGAQRRTVEGLNRVEAAHDNLRLTYVALTRA
Rv0630c|M.tuberculosis_H37Rv        -------DGTRCLYIGGKDGGAQRRTVEGLNRVEAAHDNLRLTYVALTRA
                                            . ***::**  .      .      * * *  **:***:***

Mflv_5130|M.gilvum_PYR-GCK          QSQVVAWWAPSRDELNGGLSRLLRGRAPGDPVVPDRCDPARIDDAEAMAR
Mvan_1209|M.vanbaalenii_PYR-1       QSQVVAWWAPSNDEPNGGLSRLLRGRAPGDPVVPDRCDPPRIDDPDAMAQ
TH_1287|M.thermoresistible__bu      QAQVVAWWAPSWDEPNGGLSRLLRGRRPGERSVPHRCPDDRITDDQAWER
MMAR_0957|M.marinum_M               QSQVVAWWSPAYDEPNGGLSRLLRGRRPGDSVVPDRATPAKITDEDAWDR
MUL_0708|M.ulcerans_Agy99           QSQVVAWWSPAYDEPNGGLSRLLRGRRPGDSVVPDRATPAKITDEDAWDR
MAV_4543|M.avium_104                QAQVVAWWSPAYHEPNGGLSRLLRGRRPGEPVVPDRCEPAKISDEDALAR
MAB_0399c|M.abscessus_ATCC_199      QSQVVAWWAPSFDEPNGGLSRLLRGRAPGNPSVPDKCSPAKISDADVLKR
MSMEG_1327|M.smegmatis_MC2_155      QSQVVAWWAPSYDEPNGGLSRLMRGRAPGEAIVPDKCSPPKISDEDALER
Mb0647c|M.bovis_AF2122/97           QSQVVAWWAPTFDEVNGGLSRLLRGRRPGQSQVPDRCTP-RVTDEQAWAV
Rv0630c|M.tuberculosis_H37Rv        QSQVVAWWAPTFDEVNGGLSRLLRGRRPGQSQVPDRCTP-RVTDEQAWAV
                                    *:******:*: .* *******:*** **:  **.:.   :: * :.   

Mflv_5130|M.gilvum_PYR-GCK          LRAWADEGGPVLEESIIAERVEVELPAPPDTLAVRHFHRRIDPLWRRTSY
Mvan_1209|M.vanbaalenii_PYR-1       LRAWSDAGGPVLEESVIAASVTVELPSPAEDLDVRHFHRRIDTSWRRTSY
TH_1287|M.thermoresistible__bu      LREWEAAGGPVLEESLPRPVTALPPEPTPTELGARHFHRSIDTDWRRTSY
MMAR_0957|M.marinum_M               FQQWQAAGGPTVEESVIAAAPAIAGRPAPSELATRRFDRGIDIRWRRTSY
MUL_0708|M.ulcerans_Agy99           FQQWQAAGGPTVEESVIAAAPAIAGQPAPSELATRRFDRDIDIRWRRTSY
MAV_4543|M.avium_104                LREWEAAGGPVIEEAVPAPAPPLPGVPVPARLENRHFHRGIDTGWRRTSY
MAB_0399c|M.abscessus_ATCC_199      LRAWEAQGGPVVEDALVTGFVPAATSSPSDNLAVRVFDRPIDTAWRRTSY
MSMEG_1327|M.smegmatis_MC2_155      LRAWEAAGGPVIEESVIGAVSPVPPEPAPEDLAARKFFRAIDMAWKRTSY
Mb0647c|M.bovis_AF2122/97           FAQWEAAGGPSVEESVIGARSSLEKPVPVPGFEVRHFHRRIDTTWRRTSY
Rv0630c|M.tuberculosis_H37Rv        FAQWEAAGGPSVEESVIGARSSLEKPVPVPGFEVRHFHRRIDTTWRRTSY
                                    :  *   *** :*:::               :  * * * **  *:****

Mflv_5130|M.gilvum_PYR-GCK          SGLIRAAEQE--------SGVGSEPEVVELDDEVAELRAPDTEPATPDVD
Mvan_1209|M.vanbaalenii_PYR-1       SGLIRAAESEQ-------TGVGSEPEVVELDDEAGEVPVPGAGGGGD--Q
TH_1287|M.thermoresistible__bu      SGLLRASQSDGGVAASGSPGVTSEPEVAELDDEVGEIPLT---PATDGAE
MMAR_0957|M.marinum_M               SGLIRMAEAT---------GVSSEPEVTERDDEVAEVPLTEVVMSGP--E
MUL_0708|M.ulcerans_Agy99           SGLIRMAEAT---------GVSSEPEVTERDDEVAEVPLTEVVMSGP--E
MAV_4543|M.avium_104                SGLIRQAQPS---------GVGSEPEAAGLDDEVGDILLAPATSVGD---
MAB_0399c|M.abscessus_ATCC_199      SGLLRAAEES---------GVSSEPEIAELDDEVDEIPLRSMPAGAD---
MSMEG_1327|M.smegmatis_MC2_155      SGLLRAAETAG-------VGVSSEPEVTERDDEFDDIPVVAPAEGAD---
Mb0647c|M.bovis_AF2122/97           SDLVRGSEAVT---------VTSEPAAGGRADEVEIAVFAAPGSGAD---
Rv0630c|M.tuberculosis_H37Rv        SDLVRGSEAVT---------VTSEPAAGGRADEVEIAVVAAPGSGAD---
                                    *.*:* ::            * ***      **                 

Mflv_5130|M.gilvum_PYR-GCK          MASPMAGLPMGAKFGTLVHAVLETADPFAVDLAAELEAAVVEHSLWWPVD
Mvan_1209|M.vanbaalenii_PYR-1       MPSPMADLPMGAKFGTLVHAVLETADPFATDLAAELESHVRRHSLWWPVD
TH_1287|M.thermoresistible__bu      VPSPMAGLPTGAKLGTLVHAVLETADPFAPDLAAELADRVREHAVWWPVD
MMAR_0957|M.marinum_M               QPSPMADLPSGAKFGSLVHAVLETSDPFAIDLAAELESQIRVQSAWWPVQ
MUL_0708|M.ulcerans_Agy99           QPSPMADLPSGAKFGSLVHAVLETSDPFAIDLAAELESQIRVQSAWWPVQ
MAV_4543|M.avium_104                VASPMADLPAGATFGTLVHAVLQTADPFAPDLAAELTARIREHSVWWPVA
MAB_0399c|M.abscessus_ATCC_199      VPSPMAQLPAGAAFGSLVHAVLETTDPLAPDLVAELQTQIIRHRERWPVE
MSMEG_1327|M.smegmatis_MC2_155      VPSPMAHLPTGAAFGSLVHAVLETADPFAEDLTAELATHIDAHSQHWPVE
Mb0647c|M.bovis_AF2122/97           LTSPLAALPSGASFGSLVHAVLETADPAAPDLAAELEAQVP---------
Rv0630c|M.tuberculosis_H37Rv        LTSPLAALPSGASFGSLVHAVLETADPAAPDLAAELEAQVRRHAPWWTVD
                                     .**:* ** ** :*:******:*:** * **.***   :          

Mflv_5130|M.gilvum_PYR-GCK          VP----PAELAAALVPLHDTPLGPLAPGVTLRDIGLRDRLREMEFEFPLA
Mvan_1209|M.vanbaalenii_PYR-1       VP----AADLAAALVPLHDTPLGPLAPGVTLRDIGLRDRLREMEFEFPLA
TH_1287|M.thermoresistible__bu      VP----AEELAAALVPVHDTPLGPLAPGLTLRQIGLRDRMREMEFEFPLA
MMAR_0957|M.marinum_M               VP----AAQLAAALVPMHDTPLGPLAGGLTLRQIGLPDRLREMDFEFPLA
MUL_0708|M.ulcerans_Agy99           VP----AAQLAAALVPMHDTPLGPLAGGLTLRQIGLPDRLREMDFEFPLA
MAV_4543|M.avium_104                AT----PEDMAAAMVPMHDTPLGPLAGGLTLRRIGLSDRLCELDFELPLA
MAB_0399c|M.abscessus_ATCC_199      IP----AAELAAALEPMHDTPLGPLLPGVTLRQIGLRDRLCELDFEFPLA
MSMEG_1327|M.smegmatis_MC2_155      VE----TAELAAALVPMHDTPLGPLAPGLTLRQIGLRDRLCELDFEFPMA
Mb0647c|M.bovis_AF2122/97           --------------------------------------------------
Rv0630c|M.tuberculosis_H37Rv        VDHAQLAPELARALLPMHDTPLGPAAAALTLRQIGVRDRLRELDFEMPLA
                                                                                      

Mflv_5130|M.gilvum_PYR-GCK          GGDRRDD---TPDITLADVGRLLRAHLPADDPLAPYAARLTTGALAGQPL
Mvan_1209|M.vanbaalenii_PYR-1       GGDRRVE---VPDISLADVGRLLAAHLPADDPLAPYAERLTGGTLAAQSL
TH_1287|M.thermoresistible__bu      GGDARDA---APDIRLADVGDLLGAHLPEDDPLACYAERLTGTGLGRQPL
MMAR_0957|M.marinum_M               GGDEADAGGHAPDLRLADVGALLRAHLDASDPLAPYADRLSGDALGGQSL
MUL_0708|M.ulcerans_Agy99           GGDEADAGGHAPDLRLADVGALLRAHLDASDPLAPYDDRLSGDALGGQTL
MAV_4543|M.avium_104                GGDRRSA---PPEVRLADLAPLLRAHLPADDVLACYADRLTDRSLGAESL
MAB_0399c|M.abscessus_ATCC_199      GGDAAAD----SFARLADVGMLLREHLAADDPLGVYASRLTGPGLGGQSL
MSMEG_1327|M.smegmatis_MC2_155      GGDLRGG----RFARLSDVGELLREYLPADDPLAVYAERLSTGILGVQPL
Mb0647c|M.bovis_AF2122/97           -GTRRG-------------------------------------GPWTSTT
Rv0630c|M.tuberculosis_H37Rv        GGDLRGR---SPDVSLADVGELLASHLPGDDPLSPYADRLGSAGLGDQPL
                                     *                                             .. 

Mflv_5130|M.gilvum_PYR-GCK          KGYLNGSLDAVLRVDG----RYLVVDYKTNWLGDPAGELTAADYAPARLA
Mvan_1209|M.vanbaalenii_PYR-1       KGYLNGSVDAVLRVGD----RYLVVDYKTNWLGDPARPLTAADYGKARLT
TH_1287|M.thermoresistible__bu      RGYLTGSVDAVLRIPAGDDHRYLVVDYKTNWLGPVDRPLTAADYTRPRLV
MMAR_0957|M.marinum_M               RGYLSGSVDAVLRIPDGPGQRYLVVDYKTNWLGDPDRPLTAADYHRPRLI
MUL_0708|M.ulcerans_Agy99           RGYLSGSVDVVLRIPDGPGQRYLVVDYKTNWLGDPDRPLTAADYHRPRLI
MAV_4543|M.avium_104                RGYLTGSIDAVLRIPDGAGHRYLVVDYKTNRLGDAQHPLTAADYDRPRMV
MAB_0399c|M.abscessus_ATCC_199      RGYLSGSVDAVLRVGS----RYVVVDYKTNWLGTGDAPLTAADYSRPRMV
MSMEG_1327|M.smegmatis_MC2_155      RGYLSGSVDAVLRVGE----KFVIVDYKTNWLGTGDGTLTAADYGRRRMV
Mb0647c|M.bovis_AF2122/97           RSWLP---------------------------------------------
Rv0630c|M.tuberculosis_H37Rv        RGYLAGSIDVVLRLPG---QRYLVVDYKTNHLGD-----TAADYGFERLT
                                    :.:*                                              

Mflv_5130|M.gilvum_PYR-GCK          EAMLHSDYPLQALLYCVVLHRFLRWRQPGYSARRHIAGVLYLFVRGMCGP
Mvan_1209|M.vanbaalenii_PYR-1       EVMLHSDYPLQALLYCVVLHRFLRWRAPGYRAESHIAGVLYLFVRGMCGA
TH_1287|M.thermoresistible__bu      EAMLHSDYPLQALLYSVVLHRFLRWRLPAYTPEEHLGGVLYLFLRGMCGP
MMAR_0957|M.marinum_M               EAMLHSDYPLQALLYTVVLHRFLRWRQPGYDPARHLGGVLYLFVRGMCGP
MUL_0708|M.ulcerans_Agy99           EAMLHSDYPLQALLYTVVLHRFLRWRQPGYDPARHLGGVLYLFVRGMCGP
MAV_4543|M.avium_104                EAMLHSDYPLQALLYSAVLHRFLRWRLAGYDPDRHLGGILYLFVRGMCGP
MAB_0399c|M.abscessus_ATCC_199      EAMLHSDYPLQALLYSVVLHRFLSWRLPGYRPEEHLGGAVYLFVRGMCGA
MSMEG_1327|M.smegmatis_MC2_155      EAMLHSDYPLQALLYAVVLHRYLGWRLSGYDPATHLGGVLYLFVRGMCGA
Mb0647c|M.bovis_AF2122/97           -----------------------NWPER------------------CCRC
Rv0630c|M.tuberculosis_H37Rv        EAMLHSDYPLQALLYVVVLHRFLRWRQRDYAPARHLGGVLYLFVRGMCGA
                                                            *                      *  

Mflv_5130|M.gilvum_PYR-GCK          DTPVLDGHPAGVFSWQPPAALIEELSDLLDAGAVPA
Mvan_1209|M.vanbaalenii_PYR-1       DTPVVDGHPAGVFSWQPPAALIEALSDLLDAGVAA-
TH_1287|M.thermoresistible__bu      DTPVVDGHPAGVFSWQPPAGLVVALSDLLDAGRTAE
MMAR_0957|M.marinum_M               DTPMLDGHPAGVFSWSPPAALVTALSDLLDAGRAVA
MUL_0708|M.ulcerans_Agy99           DTPMLDGHPAGVFSWSPPAALVTALSDLLDAGRAVA
MAV_4543|M.avium_104                DTPVRDGHPSGVFDWRPPSSLIAALSDLLDAQGVAV
MAB_0399c|M.abscessus_ATCC_199      TTPVVEGHPAGVFSWQPPSALVVALSELLS------
MSMEG_1327|M.smegmatis_MC2_155      GTPVVDGHPAGVFSWEPPADLVVALSKLLDAEAP--
Mb0647c|M.bovis_AF2122/97           TTRR----------WDPPPPH---------------
Rv0630c|M.tuberculosis_H37Rv        ATPVTAGHPAGVFTWNPPTALVVALSDLLDRGRLQS
                                     *            * **.