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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_1287 | recB | - | 100% (682) | PROBABLE EXONUCLEASE V (BETA CHAIN) RECB (EXODEOXYRIBONUCLEASE V BETA CHAIN)(EXODEOXYRIBONUCLEASE V POLYPEPTIDE) (CHI-SPECIFIC ENDONUCLEASE) |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0647c | recBa | 1e-153 | 64.64% (444) | exonuclease V subunit beta |
M. gilvum PYR-GCK | Mflv_5130 | - | 0.0 | 68.90% (688) | exodeoxyribonuclease V, beta subunit |
M. tuberculosis H37Rv | Rv0630c | recB | 0.0 | 66.23% (684) | exonuclease V beta chain |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_0399c | - | 0.0 | 68.69% (677) | exodeoxyribonuclease V, beta subunit (RecB) |
M. marinum M | MMAR_0957 | recB | 0.0 | 70.97% (682) | exodeoxyribonuclease V (beta chain), RecB |
M. avium 104 | MAV_4543 | recB | 0.0 | 71.60% (676) | exodeoxyribonuclease V, beta subunit |
M. smegmatis MC2 155 | MSMEG_1327 | recB | 0.0 | 71.26% (675) | exodeoxyribonuclease V, beta subunit |
M. ulcerans Agy99 | MUL_0708 | recB | 0.0 | 70.67% (682) | exodeoxyribonuclease V (beta chain), RecB |
M. vanbaalenii PYR-1 | Mvan_1209 | - | 0.0 | 71.55% (682) | exodeoxyribonuclease V, beta subunit |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_5130|M.gilvum_PYR-GCK MEPFDLLGALPEPRTTTVLEASAGTGKTFALAGLVTRYVAEGVATLDRML Mvan_1209|M.vanbaalenii_PYR-1 MEPFDLLGPLPAPRTTTVLEASAGTGKTFALAGLVTRYVAEGVATLDQML TH_1287|M.thermoresistible__bu -------------------------------------------------- MMAR_0957|M.marinum_M MRPFDLLGPLPAENSTTVLEASAGTGKTFALAALVTRYVAEGRARLDEML MUL_0708|M.ulcerans_Agy99 MRPFDLLGPLPAENSTTVLEASAGTGKTFALAALVTRYVAEGRARLDEML MAV_4543|M.avium_104 MERFDLLGALPAARSTTVLEASAGTGKTFALAGLVTRYLADGAATLDQML MAB_0399c|M.abscessus_ATCC_199 MKRFDLLGPLPADRSTTVLEASAGTGKTFALAGLVTRYVAEGVATLDQML MSMEG_1327|M.smegmatis_MC2_155 MKVFDLLGPLPAPNTTTVLEASAGTGKTFALAGLVTRFVAEGVATLDQML Mb0647c|M.bovis_AF2122/97 MDRFELLGPLPREGTTTVLEASAGTGKTFALAGLVTRYLAETAATLDEML Rv0630c|M.tuberculosis_H37Rv MDRFELLGPLPREGTTTVLEASAGTGKTFALAGLVTRYLAETAATLDEML Mflv_5130|M.gilvum_PYR-GCK LITFGRAASQELRERVRSQIVDALRAFDDP-------AAIGDNEVVRHLV Mvan_1209|M.vanbaalenii_PYR-1 LITFGRAASQELRERVRAQILDALRAFDDP-------SHAADNEIVAHLL TH_1287|M.thermoresistible__bu -------------------------------------------------- MMAR_0957|M.marinum_M LITFGRAASQELRERVRCQMVDAVRVFHDSRNGSDDADPAGDNQLLAHLL MUL_0708|M.ulcerans_Agy99 LITFGRAASQELRERVRCQMVDAVRVFHDSRNGSDDADPAGDNQLLAHLL MAV_4543|M.avium_104 LITFGRAASQELRERVRCQIVDAVAAFADP-------SRAGDNELVAYLL MAB_0399c|M.abscessus_ATCC_199 LITFGRAASQELRDRVRGQIVDALRAFADP--------STARTDLTQYLI MSMEG_1327|M.smegmatis_MC2_155 LITFGRAASQELRERVRAQIVAALVALDDP--------SRACNDLEEYLV Mb0647c|M.bovis_AF2122/97 LITFNRAASRELRERVRGQIVEALGALQGD--------APPSGELVEHLL Rv0630c|M.tuberculosis_H37Rv LITFNRAASRELRERVRGQIVEAVGALQGD--------APPSGELVEHLL Mflv_5130|M.gilvum_PYR-GCK TGDAEECDARRRRLRDALAGFDAATIATTHQFCQLVLRSLGVAGDTDSGV Mvan_1209|M.vanbaalenii_PYR-1 TGSHGELTERRQRLRDALAGFDAATIATTHQFCQLVLRSLGVAGDTDSGV TH_1287|M.thermoresistible__bu -------------------------------------------------- MMAR_0957|M.marinum_M DGTAAERDARQQRLRDALAGFDAATIATTHQFCQLVLKSLGVAGDTDAGV MUL_0708|M.ulcerans_Agy99 DGTAAERDARQQRLRDALAGFDAATIATTHQFCQLVLKSLGVAGDTDAGV MAV_4543|M.avium_104 DGTEDRLAARRQRLRDGLAGFDAATIATTHQFCQLVLRSLGVAGDTAAGV MAB_0399c|M.abscessus_ATCC_199 S---AEQDTRQRRLRDALAGFDAATIATTHQFCHIVLKSLGVAGDSDSGV MSMEG_1327|M.smegmatis_MC2_155 K---TDQQARRRRLRDALAGFDAATIATTHQFCQIVLKSLGVAGDSDAGV Mb0647c|M.bovis_AF2122/97 RGSDAERAQKRSRLRDALANFDAATIATTHEFCGSVLKSLGVAGDNAADV Rv0630c|M.tuberculosis_H37Rv RGSDAERAQKRSRLRDALANFDAATIATTHEFCGSVLKSLGVAGDNAADV Mflv_5130|M.gilvum_PYR-GCK ELVESLDDLVAEIVDDLYLAHFGQDRDEPLLTHESALRLAHAVVGNAHTE Mvan_1209|M.vanbaalenii_PYR-1 ELVESLDDLVTEIVDDLYLAHFGQDHDEPLLTYADALSLAREVVGNAHTE TH_1287|M.thermoresistible__bu -------------------------------------------------- MMAR_0957|M.marinum_M TLVEDLDELVTEIVDDLYLVHFGRDRDDPPLTYRDALRIARAVVANPSTQ MUL_0708|M.ulcerans_Agy99 TLVEDLDELVTEIVDDLYLVHFGRDRDDPPLTYRDALRIARAVVANPSTQ MAV_4543|M.avium_104 TLLDSLDELVAEIVDDLYLAHFGQDHDDPVLHYREALRLARDVVNNPSAQ MAB_0399c|M.abscessus_ATCC_199 TLVENLDELVCEIVNDRYLTHFGKDRDAPPLSYPAALRLAREVVRNPATQ MSMEG_1327|M.smegmatis_MC2_155 TLVESLDDLVSEIVDDLYLAHFGGQKDDPELSYPEALKLARVVVGNPATQ Mb0647c|M.bovis_AF2122/97 ELKESLTDLVTEIVDDRYLANFGRQETDPELTYAEALALALAVVDDPCAQ Rv0630c|M.tuberculosis_H37Rv ELKESLTDLVTEIVDDRYLANFGRQETDPELTYAEALALALAVVDDPCAQ Mflv_5130|M.gilvum_PYR-GCK LRPRDPAPGSDAAVRVEFAKAVCAELETRKRKLGILHYDDLLSRLADALE Mvan_1209|M.vanbaalenii_PYR-1 LRPTDPPPGSDPFVRVQFARAVCAELETRKRRLGILHYDDLLSRLAKALE TH_1287|M.thermoresistible__bu -------------------------------------------------- MMAR_0957|M.marinum_M LRPLDAPPGSRAAICVGFAHHVLEELETRKRRRGILGYDDLLLRLADALA MUL_0708|M.ulcerans_Agy99 LRPLDAPPGSRAAACVGFAHHVLEGLETRKRRRGILGYDDLLLRLADALA MAV_4543|M.avium_104 LRPLHPEPGSRAAVSLRFANDVLAELDTRKRRLGVLGYDDLLTRLADALA MAB_0399c|M.abscessus_ATCC_199 LRPLQPEADSYAFAALGFARDVLEQLEIRKRRRGILGFDDLLTRLADALN MSMEG_1327|M.smegmatis_MC2_155 LRPRDPDPDSPAAVRLKFARDVLAELEIRKRRRGVLGYDDLLTRLADALE Mb0647c|M.bovis_AF2122/97 LRPPDPEPGSKAAVRLRFAAEVLEELERRKGRLRAQGFNDLLIRLATALE Rv0630c|M.tuberculosis_H37Rv LRPPDPEPGSKAAVRLRFAAEVLEELERRKGRLRAQGFNDLLIRLATALE Mflv_5130|M.gilvum_PYR-GCK APDSPARARMQRRWSIVMVDEFQDTDPVQWQVIDRAFRGHATLILIGDPK Mvan_1209|M.vanbaalenii_PYR-1 PQDSPARMRMQHRWSIVMVDEFQDTDPVQWQVIDCAFSGHATVILIGDPK TH_1287|M.thermoresistible__bu -------------------------------------------------- MMAR_0957|M.marinum_M SEDSAARARMQQRWPVVMVDEFQDTDAVQWQVIDSAFSGRCTLILIGDPK MUL_0708|M.ulcerans_Agy99 SEDSAARARMQQRWPVVMVDEFQDTDAVQWQVIDSAFSGRCTLILIGDPK MAV_4543|M.avium_104 TEHSPARLRMHQRWPIVMVDEFQDTDPVQWQVIDRAFSGRSTLILIGDPK MAB_0399c|M.abscessus_ATCC_199 ATDSPARVRMHQRWPIVMVDEFQDTDPVQWQVLERAFSGHSTLVLIGDPK MSMEG_1327|M.smegmatis_MC2_155 PEDSPARVRMQQRWPIVMVDEFQDTDPVQWQVIERAFSGRSTLVLIGDPK Mb0647c|M.bovis_AF2122/97 AADSPARDRMRERWRIVLVDEFQDTDPMQWRVLERAFSRHSALILIGDPK Rv0630c|M.tuberculosis_H37Rv AADSPARDRMRERWRIVLVDEFQDTDPMQWRVLERAFSRHSALILIGDPK Mflv_5130|M.gilvum_PYR-GCK QAIYAFRGGDIVTYLHAAATAGVQRTLGTNYRSDAPLVEGLQAVMRDAQL Mvan_1209|M.vanbaalenii_PYR-1 QAIYAFRGGDIVTYLHAVSTADRQKTLGTNYRSDGPLVDSLQAVMRDAQL TH_1287|M.thermoresistible__bu -------------------------------------------------- MMAR_0957|M.marinum_M QAIYAFRGGDIVTYLHAAQTAGDKRTLATNWRSDSALVDRLQVVLRGAEL MUL_0708|M.ulcerans_Agy99 QAIYAFRGGDIVTYLHAAQTAGDKRTLATNWRSDSALVDRLQVVLRGAEL MAV_4543|M.avium_104 QAIYAFRGGDIVTYLRAAETAGQKKTLDTNWRSDSALLQRLQVVLRGAQL MAB_0399c|M.abscessus_ATCC_199 QAIYAFRGGDIETYLRAAATAGDKQTLGTNWRSDAALVDRLQVVLRGAQL MSMEG_1327|M.smegmatis_MC2_155 QAIYAFRGGDIATYLRAAATAGDKQTLGTNWRSDRALVDRLQAVLRGAQL Mb0647c|M.bovis_AF2122/97 QAIYGFRGGDIHTYLKAAGTADARYTLGVNWRSDRALVESLQTVLRDATL Rv0630c|M.tuberculosis_H37Rv QAIYGFRGGDIHTYLKAAGTADARYTLGVNWRSDRALVESLQTVLRDATL Mflv_5130|M.gilvum_PYR-GCK GDPRIVVRRVDAHHREHRLQGAPHNEPFRLRVCTRDQFRVRPDRMIPIDV Mvan_1209|M.vanbaalenii_PYR-1 GDPRIVAHRVEAHHRDHRLAGAPRNAPFRLRVVTRDQFGTRPDRVVAIDQ TH_1287|M.thermoresistible__bu -------------------------------------------------- MMAR_0957|M.marinum_M GDPAIVVRDVKAHHQGHRLAGAPHNDALRLRVVRRATLGRRGIQNLPIDI MUL_0708|M.ulcerans_Agy99 GDPAIVVRDVKAHHQGHRLAGAPHNDALRLRVVRRATLGRRGIQNLPIDI MAV_4543|M.avium_104 GDPAIVVNDVAAHHRGHRLSGAPRNDPFRLRVVSRNTLGRRGIANLPIDE MAB_0399c|M.abscessus_ATCC_199 GGPDIVVHDVQAHHQGHRLAGAPHNDPFRLRVVSRN---RDGIKVIPIAD MSMEG_1327|M.smegmatis_MC2_155 GGPDIVVHDVQARHQGHRLVGAPRNDPFRLRVVSRK---PGNTRVIPIDQ Mb0647c|M.bovis_AF2122/97 GHADIVVRGTDAHHAGHRLASAPRPAPFRLRVVKRHTLGYDGTAHVPIEA Rv0630c|M.tuberculosis_H37Rv GHADIVVRGTDAHHAGHRLASAPRPAPFRLRVVKRHTLGYDGTAHVPIEA Mflv_5130|M.gilvum_PYR-GCK LRNHIPKDMAADIAALLNSGATHCGEKLAPGHIAVIVESHRDGHACFAAL Mvan_1209|M.vanbaalenii_PYR-1 LRRHIPQDMAADIAALLASDATFCDRPVQPGDVAVIVESHRDGHACFDAL TH_1287|M.thermoresistible__bu ------------------------------------VETHKDARACYDAL MMAR_0957|M.marinum_M LRDHIGRDLASDIGALLASGATFAGRALQANDIAVIVEKHKDARACHRAL MUL_0708|M.ulcerans_Agy99 LRDHIGRDLASDIGALLASGATFAGRALQANDIAVIVEKHKDARACHRAL MAV_4543|M.avium_104 LRQHIGADLAADIRALLAAGATFDGKPVRAGDIAVIVERHRDAQACFTAL MAB_0399c|M.abscessus_ATCC_199 LRRSIGRDLAADIGALLSSGATFDGRPVRARDIAVIVEAHKDARACHTAL MSMEG_1327|M.smegmatis_MC2_155 LRRHIGRDLAADISALLNSGATWCDQPVQAKDIAVITETHKDARACHAAL Mb0647c|M.bovis_AF2122/97 LRRHIPDDLAADVAALLASGATFAGRPVVAADIAVIVEHHKDARACRNAL Rv0630c|M.tuberculosis_H37Rv LRRHIPDDLAADVAALLASGATFAGRPVVAADIAVIVEHHKDARACRNAL .* *:*.:** ** Mflv_5130|M.gilvum_PYR-GCK ADAGIPAVYTGDSDVFSSPAADDWMCLLEAFDQPHRSGLVRAAATTMFFG Mvan_1209|M.vanbaalenii_PYR-1 TAAGIPAVYTGDSDVFTSPAADDWMCLLEAFDQPHRSGLVRAAATTMFFG TH_1287|M.thermoresistible__bu CQAGIPAVYTGDSDVFGSPAAEDWLCLLEAFDQPHRPGMVRAAAATMFFG MMAR_0957|M.marinum_M TDAGIHAVYTGDTDVFSSEAADDWLALLEAFDQPHRPGIVRAAAATMFFG MUL_0708|M.ulcerans_Agy99 TDAGIHAVYTGDTDVFSSEAADDWLALLEAFDQPHRPGIVRAAAATMFFG MAV_4543|M.avium_104 CDAGVPAVYTGNSDVFTSQAAEDWLCLLEAFDQPHRPGVVRAAAATMFFG MAB_0399c|M.abscessus_ATCC_199 TEAGIPAVYTGDTDVFSSDAAQDWLYLLEAFDQPHRPGLVRAAAATVFFG MSMEG_1327|M.smegmatis_MC2_155 LAAGIPAVYTGDSDVFTSEAAEDWLYLLEAFDQPHRPGLVRAAAATMFFG Mb0647c|M.bovis_AF2122/97 AEAGIPAIYTGDTDVFASQAAKDWLCLLEAFDAPQRSGLVRAAACTMFFG Rv0630c|M.tuberculosis_H37Rv AEAGIPAIYTGDTDVFASQAAKDWLCLLEAFDAPQRSGLVRAAACTMFFG **: *:***::*** * **.**: ****** *:*.*:***** *:*** Mflv_5130|M.gilvum_PYR-GCK ETAEALALQGDSLTDRIAETLRQWADFARERGVAAVFEAAQLRGMGARVL Mvan_1209|M.vanbaalenii_PYR-1 ETAESLAAEGDTLTDRVAETLRQWADFARDRGVAAVFEAAQLGGMGERVL TH_1287|M.thermoresistible__bu ETAESLAAGGDALTDRVADTLREWAAHARERGVAAIFEAAKLSGMGDRVL MMAR_0957|M.marinum_M KTANDLARGGDALTDRVAETLREWADYARERGVAAIFEAAQLGGMSDRVL MUL_0708|M.ulcerans_Agy99 KTANDLARGGDALTDRVAETLREWADYARERGVAAIFEAAQLGGMSDRVL MAV_4543|M.avium_104 ETAETLAAGGDALTDRIAQTLREWAGHARERGVAAIFEAAQLLGMGNRVL MAB_0399c|M.abscessus_ATCC_199 ETAETLAVGGESLTDEIAGTLRTWAARARERGVAAVFEAAQLAGMGKRVL MSMEG_1327|M.smegmatis_MC2_155 ETAESLAAGGDALTDRVADTLREWAGHARERGVAAIFEAAQLAGMGKRVL Mb0647c|M.bovis_AF2122/97 ETAESLAAEGDALTDRVAGTLREWADHARHRGVAAVFQAAQLAGMGRRVL Rv0630c|M.tuberculosis_H37Rv ETAESLAAEGDALTDRVAGTLREWADHARHRGVAAVFQAAQLAGMGRRVL :**: ** *::***.:* *** ** **.*****:*:**:* **. *** Mflv_5130|M.gilvum_PYR-GCK RWVDGERHMTDLAHLTQLLHDTAHREQYSLPALRDWLRAQRDDRGGLRGT Mvan_1209|M.vanbaalenii_PYR-1 SWVDGERHMTDLAHLTQVLHGTAHREHFSLPALRDWLRGQRDERS---GA TH_1287|M.thermoresistible__bu SWADGERHMTDLAHIAQLLQEAAHRDHLGLPALRDWLRARREETSG--GA MMAR_0957|M.marinum_M SWQEGQRHMTDLAHVTQLLQKVSHRERYTLPALRDWLRGQREDRG---GA MUL_0708|M.ulcerans_Agy99 SWQEGQRHMTDLAHVTQLLQKVSHRERYTLPALRDWLRGQREDRG---GA MAV_4543|M.avium_104 GWQGGARHMTDLAHLTQLLGEVAHCEHHNLPALRDWLRRQRDERS---GA MAB_0399c|M.abscessus_ATCC_199 SWRGGERMMTDLAHLTELLQETAHRNGFGPAALRDWLRTQCSEGG---AE MSMEG_1327|M.smegmatis_MC2_155 SWQGGERLMTDLAHMTQLLQDTAHREGFGLAALRDWLRTQRSERG---GE Mb0647c|M.bovis_AF2122/97 SQRGGERDLTDLAHIAQLLHEAAHRERLGLPGLRDWLRRQAKAGA---GP Rv0630c|M.tuberculosis_H37Rv SQRGGERDLTDLAHIAQLLHEAAHRERLGLPGLRDWLRRQAKAGA---GP * * :*****::::* .:* : ..****** : . . . Mflv_5130|M.gilvum_PYR-GCK VERNRRLDSDAAAVQIMTVWVSKGLQFPVVYLPFAFNRNVQPRDVVVFHE Mvan_1209|M.vanbaalenii_PYR-1 PERNRRLDSDAAAVQIMTVWVSKGLQFPVVYLPFAFNRNIQTRDVVTFHD TH_1287|M.thermoresistible__bu TERFRRLDTDAAAVPVMTVFAAKGLQFPVVYLPFAFNRHVRKQELVLYHE MMAR_0957|M.marinum_M TERNRRIDSDAAAVQIMTVWVSKGLQYPVVYLPFAFNRNIQERELVLFHD MUL_0708|M.ulcerans_Agy99 TERNRRIDSDAAAVQIMTVWVSKGLQYPVVYLPFAFNRNIQERELVLFHD MAV_4543|M.avium_104 PERNRRLDSDAAAVQIMTVFVSKGLQYPIVYLPFAFHRNTTDSDVVLFHD MAB_0399c|M.abscessus_ATCC_199 AERNRRLDSDAAAVQIMTVWVSKGLQFPVVYLPFSFNRYVPEREYVLYHE MSMEG_1327|M.smegmatis_MC2_155 SERNRRLDSDAAAVQIMTVWVSKGLQFPVVYLPFAFNRYVPEPDLVLFHD Mb0647c|M.bovis_AF2122/97 PEHNRRLDSDAAAVQIMTVFVAKGLQFPIVYLPFAFNRNVRSDDILLYHD Rv0630c|M.tuberculosis_H37Rv PEHNRRLDSDAAAVQIMTVFVAKGLQFPIVYLPFAFNRNVRSDDILLYHD *: **:*:***** :***:.:****:*:*****:*:* : : :*: Mflv_5130|M.gilvum_PYR-GCK PATSDGAGDIRCLHIGGESSPDFA-AVAQQARLEAAGDDVRLTYVAMTRA Mvan_1209|M.vanbaalenii_PYR-1 -------GDIRCLHIGGERSPDHA-AAQQQGRREAAGDDVRLTYVAMTRA TH_1287|M.thermoresistible__bu ------DDGTRCLHIGGSDSPDHP-QVAQRGRDEDASDDGRLTYVALTRA MMAR_0957|M.marinum_M -------GGTRCLHIGGKDSPDFG-TVERLGAKEAANDDSRLTYVAMTRA MUL_0708|M.ulcerans_Agy99 -------RGTRCLHIGGKDSPDFG-TVERLGAKEAANDDSRLTYVAMTRA MAV_4543|M.avium_104 ------EDGTRCLHVGGKDSPDFK-TVERLGRKEDASDDSRLTYVALTRA MAB_0399c|M.abscessus_ATCC_199 -------DGLRCLHIGGREDPDYS-MADLAGRTEAARDASRLAYVALTRA MSMEG_1327|M.smegmatis_MC2_155 -------DGQRCLHVGG-ADP----AVARAGRAEAAGDDSRLTYVALTRA Mb0647c|M.bovis_AF2122/97 -------DGTRCLYIGGKDGGAQRRTVEGLNRVEAAHDNLRLTYVALTRA Rv0630c|M.tuberculosis_H37Rv -------DGTRCLYIGGKDGGAQRRTVEGLNRVEAAHDNLRLTYVALTRA . ***::** . . * * * **:***:*** Mflv_5130|M.gilvum_PYR-GCK QSQVVAWWAPSRDELNGGLSRLLRGRAPGDPVVPDRCDPARIDDAEAMAR Mvan_1209|M.vanbaalenii_PYR-1 QSQVVAWWAPSNDEPNGGLSRLLRGRAPGDPVVPDRCDPPRIDDPDAMAQ TH_1287|M.thermoresistible__bu QAQVVAWWAPSWDEPNGGLSRLLRGRRPGERSVPHRCPDDRITDDQAWER MMAR_0957|M.marinum_M QSQVVAWWSPAYDEPNGGLSRLLRGRRPGDSVVPDRATPAKITDEDAWDR MUL_0708|M.ulcerans_Agy99 QSQVVAWWSPAYDEPNGGLSRLLRGRRPGDSVVPDRATPAKITDEDAWDR MAV_4543|M.avium_104 QAQVVAWWSPAYHEPNGGLSRLLRGRRPGEPVVPDRCEPAKISDEDALAR MAB_0399c|M.abscessus_ATCC_199 QSQVVAWWAPSFDEPNGGLSRLLRGRAPGNPSVPDKCSPAKISDADVLKR MSMEG_1327|M.smegmatis_MC2_155 QSQVVAWWAPSYDEPNGGLSRLMRGRAPGEAIVPDKCSPPKISDEDALER Mb0647c|M.bovis_AF2122/97 QSQVVAWWAPTFDEVNGGLSRLLRGRRPGQSQVPDRCTP-RVTDEQAWAV Rv0630c|M.tuberculosis_H37Rv QSQVVAWWAPTFDEVNGGLSRLLRGRRPGQSQVPDRCTP-RVTDEQAWAV *:******:*: .* *******:*** **: **.:. :: * :. Mflv_5130|M.gilvum_PYR-GCK LRAWADEGGPVLEESIIAERVEVELPAPPDTLAVRHFHRRIDPLWRRTSY Mvan_1209|M.vanbaalenii_PYR-1 LRAWSDAGGPVLEESVIAASVTVELPSPAEDLDVRHFHRRIDTSWRRTSY TH_1287|M.thermoresistible__bu LREWEAAGGPVLEESLPRPVTALPPEPTPTELGARHFHRSIDTDWRRTSY MMAR_0957|M.marinum_M FQQWQAAGGPTVEESVIAAAPAIAGRPAPSELATRRFDRGIDIRWRRTSY MUL_0708|M.ulcerans_Agy99 FQQWQAAGGPTVEESVIAAAPAIAGQPAPSELATRRFDRDIDIRWRRTSY MAV_4543|M.avium_104 LREWEAAGGPVIEEAVPAPAPPLPGVPVPARLENRHFHRGIDTGWRRTSY MAB_0399c|M.abscessus_ATCC_199 LRAWEAQGGPVVEDALVTGFVPAATSSPSDNLAVRVFDRPIDTAWRRTSY MSMEG_1327|M.smegmatis_MC2_155 LRAWEAAGGPVIEESVIGAVSPVPPEPAPEDLAARKFFRAIDMAWKRTSY Mb0647c|M.bovis_AF2122/97 FAQWEAAGGPSVEESVIGARSSLEKPVPVPGFEVRHFHRRIDTTWRRTSY Rv0630c|M.tuberculosis_H37Rv FAQWEAAGGPSVEESVIGARSSLEKPVPVPGFEVRHFHRRIDTTWRRTSY : * *** :*::: : * * * ** *:**** Mflv_5130|M.gilvum_PYR-GCK SGLIRAAEQE--------SGVGSEPEVVELDDEVAELRAPDTEPATPDVD Mvan_1209|M.vanbaalenii_PYR-1 SGLIRAAESEQ-------TGVGSEPEVVELDDEAGEVPVPGAGGGGD--Q TH_1287|M.thermoresistible__bu SGLLRASQSDGGVAASGSPGVTSEPEVAELDDEVGEIPLT---PATDGAE MMAR_0957|M.marinum_M SGLIRMAEAT---------GVSSEPEVTERDDEVAEVPLTEVVMSGP--E MUL_0708|M.ulcerans_Agy99 SGLIRMAEAT---------GVSSEPEVTERDDEVAEVPLTEVVMSGP--E MAV_4543|M.avium_104 SGLIRQAQPS---------GVGSEPEAAGLDDEVGDILLAPATSVGD--- MAB_0399c|M.abscessus_ATCC_199 SGLLRAAEES---------GVSSEPEIAELDDEVDEIPLRSMPAGAD--- MSMEG_1327|M.smegmatis_MC2_155 SGLLRAAETAG-------VGVSSEPEVTERDDEFDDIPVVAPAEGAD--- Mb0647c|M.bovis_AF2122/97 SDLVRGSEAVT---------VTSEPAAGGRADEVEIAVFAAPGSGAD--- Rv0630c|M.tuberculosis_H37Rv SDLVRGSEAVT---------VTSEPAAGGRADEVEIAVVAAPGSGAD--- *.*:* :: * *** ** Mflv_5130|M.gilvum_PYR-GCK MASPMAGLPMGAKFGTLVHAVLETADPFAVDLAAELEAAVVEHSLWWPVD Mvan_1209|M.vanbaalenii_PYR-1 MPSPMADLPMGAKFGTLVHAVLETADPFATDLAAELESHVRRHSLWWPVD TH_1287|M.thermoresistible__bu VPSPMAGLPTGAKLGTLVHAVLETADPFAPDLAAELADRVREHAVWWPVD MMAR_0957|M.marinum_M QPSPMADLPSGAKFGSLVHAVLETSDPFAIDLAAELESQIRVQSAWWPVQ MUL_0708|M.ulcerans_Agy99 QPSPMADLPSGAKFGSLVHAVLETSDPFAIDLAAELESQIRVQSAWWPVQ MAV_4543|M.avium_104 VASPMADLPAGATFGTLVHAVLQTADPFAPDLAAELTARIREHSVWWPVA MAB_0399c|M.abscessus_ATCC_199 VPSPMAQLPAGAAFGSLVHAVLETTDPLAPDLVAELQTQIIRHRERWPVE MSMEG_1327|M.smegmatis_MC2_155 VPSPMAHLPTGAAFGSLVHAVLETADPFAEDLTAELATHIDAHSQHWPVE Mb0647c|M.bovis_AF2122/97 LTSPLAALPSGASFGSLVHAVLETADPAAPDLAAELEAQVP--------- Rv0630c|M.tuberculosis_H37Rv LTSPLAALPSGASFGSLVHAVLETADPAAPDLAAELEAQVRRHAPWWTVD .**:* ** ** :*:******:*:** * **.*** : Mflv_5130|M.gilvum_PYR-GCK VP----PAELAAALVPLHDTPLGPLAPGVTLRDIGLRDRLREMEFEFPLA Mvan_1209|M.vanbaalenii_PYR-1 VP----AADLAAALVPLHDTPLGPLAPGVTLRDIGLRDRLREMEFEFPLA TH_1287|M.thermoresistible__bu VP----AEELAAALVPVHDTPLGPLAPGLTLRQIGLRDRMREMEFEFPLA MMAR_0957|M.marinum_M VP----AAQLAAALVPMHDTPLGPLAGGLTLRQIGLPDRLREMDFEFPLA MUL_0708|M.ulcerans_Agy99 VP----AAQLAAALVPMHDTPLGPLAGGLTLRQIGLPDRLREMDFEFPLA MAV_4543|M.avium_104 AT----PEDMAAAMVPMHDTPLGPLAGGLTLRRIGLSDRLCELDFELPLA MAB_0399c|M.abscessus_ATCC_199 IP----AAELAAALEPMHDTPLGPLLPGVTLRQIGLRDRLCELDFEFPLA MSMEG_1327|M.smegmatis_MC2_155 VE----TAELAAALVPMHDTPLGPLAPGLTLRQIGLRDRLCELDFEFPMA Mb0647c|M.bovis_AF2122/97 -------------------------------------------------- Rv0630c|M.tuberculosis_H37Rv VDHAQLAPELARALLPMHDTPLGPAAAALTLRQIGVRDRLRELDFEMPLA Mflv_5130|M.gilvum_PYR-GCK GGDRRDD---TPDITLADVGRLLRAHLPADDPLAPYAARLTTGALAGQPL Mvan_1209|M.vanbaalenii_PYR-1 GGDRRVE---VPDISLADVGRLLAAHLPADDPLAPYAERLTGGTLAAQSL TH_1287|M.thermoresistible__bu GGDARDA---APDIRLADVGDLLGAHLPEDDPLACYAERLTGTGLGRQPL MMAR_0957|M.marinum_M GGDEADAGGHAPDLRLADVGALLRAHLDASDPLAPYADRLSGDALGGQSL MUL_0708|M.ulcerans_Agy99 GGDEADAGGHAPDLRLADVGALLRAHLDASDPLAPYDDRLSGDALGGQTL MAV_4543|M.avium_104 GGDRRSA---PPEVRLADLAPLLRAHLPADDVLACYADRLTDRSLGAESL MAB_0399c|M.abscessus_ATCC_199 GGDAAAD----SFARLADVGMLLREHLAADDPLGVYASRLTGPGLGGQSL MSMEG_1327|M.smegmatis_MC2_155 GGDLRGG----RFARLSDVGELLREYLPADDPLAVYAERLSTGILGVQPL Mb0647c|M.bovis_AF2122/97 -GTRRG-------------------------------------GPWTSTT Rv0630c|M.tuberculosis_H37Rv GGDLRGR---SPDVSLADVGELLASHLPGDDPLSPYADRLGSAGLGDQPL * .. Mflv_5130|M.gilvum_PYR-GCK KGYLNGSLDAVLRVDG----RYLVVDYKTNWLGDPAGELTAADYAPARLA Mvan_1209|M.vanbaalenii_PYR-1 KGYLNGSVDAVLRVGD----RYLVVDYKTNWLGDPARPLTAADYGKARLT TH_1287|M.thermoresistible__bu RGYLTGSVDAVLRIPAGDDHRYLVVDYKTNWLGPVDRPLTAADYTRPRLV MMAR_0957|M.marinum_M RGYLSGSVDAVLRIPDGPGQRYLVVDYKTNWLGDPDRPLTAADYHRPRLI MUL_0708|M.ulcerans_Agy99 RGYLSGSVDVVLRIPDGPGQRYLVVDYKTNWLGDPDRPLTAADYHRPRLI MAV_4543|M.avium_104 RGYLTGSIDAVLRIPDGAGHRYLVVDYKTNRLGDAQHPLTAADYDRPRMV MAB_0399c|M.abscessus_ATCC_199 RGYLSGSVDAVLRVGS----RYVVVDYKTNWLGTGDAPLTAADYSRPRMV MSMEG_1327|M.smegmatis_MC2_155 RGYLSGSVDAVLRVGE----KFVIVDYKTNWLGTGDGTLTAADYGRRRMV Mb0647c|M.bovis_AF2122/97 RSWLP--------------------------------------------- Rv0630c|M.tuberculosis_H37Rv RGYLAGSIDVVLRLPG---QRYLVVDYKTNHLGD-----TAADYGFERLT :.:* Mflv_5130|M.gilvum_PYR-GCK EAMLHSDYPLQALLYCVVLHRFLRWRQPGYSARRHIAGVLYLFVRGMCGP Mvan_1209|M.vanbaalenii_PYR-1 EVMLHSDYPLQALLYCVVLHRFLRWRAPGYRAESHIAGVLYLFVRGMCGA TH_1287|M.thermoresistible__bu EAMLHSDYPLQALLYSVVLHRFLRWRLPAYTPEEHLGGVLYLFLRGMCGP MMAR_0957|M.marinum_M EAMLHSDYPLQALLYTVVLHRFLRWRQPGYDPARHLGGVLYLFVRGMCGP MUL_0708|M.ulcerans_Agy99 EAMLHSDYPLQALLYTVVLHRFLRWRQPGYDPARHLGGVLYLFVRGMCGP MAV_4543|M.avium_104 EAMLHSDYPLQALLYSAVLHRFLRWRLAGYDPDRHLGGILYLFVRGMCGP MAB_0399c|M.abscessus_ATCC_199 EAMLHSDYPLQALLYSVVLHRFLSWRLPGYRPEEHLGGAVYLFVRGMCGA MSMEG_1327|M.smegmatis_MC2_155 EAMLHSDYPLQALLYAVVLHRYLGWRLSGYDPATHLGGVLYLFVRGMCGA Mb0647c|M.bovis_AF2122/97 -----------------------NWPER------------------CCRC Rv0630c|M.tuberculosis_H37Rv EAMLHSDYPLQALLYVVVLHRFLRWRQRDYAPARHLGGVLYLFVRGMCGA * * Mflv_5130|M.gilvum_PYR-GCK DTPVLDGHPAGVFSWQPPAALIEELSDLLDAGAVPA Mvan_1209|M.vanbaalenii_PYR-1 DTPVVDGHPAGVFSWQPPAALIEALSDLLDAGVAA- TH_1287|M.thermoresistible__bu DTPVVDGHPAGVFSWQPPAGLVVALSDLLDAGRTAE MMAR_0957|M.marinum_M DTPMLDGHPAGVFSWSPPAALVTALSDLLDAGRAVA MUL_0708|M.ulcerans_Agy99 DTPMLDGHPAGVFSWSPPAALVTALSDLLDAGRAVA MAV_4543|M.avium_104 DTPVRDGHPSGVFDWRPPSSLIAALSDLLDAQGVAV MAB_0399c|M.abscessus_ATCC_199 TTPVVEGHPAGVFSWQPPSALVVALSELLS------ MSMEG_1327|M.smegmatis_MC2_155 GTPVVDGHPAGVFSWEPPADLVVALSKLLDAEAP-- Mb0647c|M.bovis_AF2122/97 TTRR----------WDPPPPH--------------- Rv0630c|M.tuberculosis_H37Rv ATPVTAGHPAGVFTWNPPTALVVALSDLLDRGRLQS * * **.