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VYLEGLAESMKTKGALIRELNKPIVVEEITFGDPAEGEVQVQLHAAGMCHSDYHVLTGATPMELPVLPGH EGAGVVTKVGKGVTSVQEGDHVIFAFIPACGKCPPCMRGYRSLCDRGAILLGGKAIADGTNRIHAGNTPV SAMNLLGTFSPYAVVHEDSVVKIDDDVPFESAALLGCAVPTGFGSSTNIAEVKPGEDVIIVGIGGIGMSA LQGAVVSGARRVIAIDPVPWKREQALKFGATHAFPTMAEALLPVMDLTWGIMAQKTIITVGEMRGEMIEE AMLLTAKTGTCVVTGMGAMVDVDVKFNLFLFTMLQKTLKGNIFGGGTTHTETPRLVGLYKQGLLKIDEMI TSTYSLEQINEGYQDMLDGKNIRGVIKYTEADW
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4560 | - | - | 100% (383) | alcohol dehydrogenase B |
| M. abscessus ATCC 19977 | MAB_2084 | - | 3e-97 | 47.97% (369) | zinc-type alcohol dehydrogenase AdhD |
| M. abscessus ATCC 19977 | MAB_0983c | - | 1e-54 | 33.15% (356) | zinc-containing alcohol dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0784c | adhB | 1e-130 | 58.29% (374) | zinc-containing alcohol dehydrogenase NAD dependant ADHB |
| M. gilvum PYR-GCK | Mflv_1593 | - | 1e-132 | 59.47% (375) | alcohol dehydrogenase |
| M. tuberculosis H37Rv | Rv0761c | adhB | 1e-130 | 58.29% (374) | zinc-containing alcohol dehydrogenase NAD dependent ADHB |
| M. leprae Br4923 | MLBr_01784 | adhE2 | 2e-48 | 33.06% (369) | putative alcohol dehydrogenase (Zn dependent) |
| M. marinum M | MMAR_4935 | adhB | 1e-130 | 58.29% (374) | zinc-containing alcohol dehydrogenase NAD- dependent AdhB |
| M. avium 104 | MAV_0705 | - | 1e-131 | 57.75% (374) | alcohol dehydrogenase B |
| M. smegmatis MC2 155 | MSMEG_0217 | - | 1e-174 | 76.47% (374) | alcohol dehydrogenase B |
| M. thermoresistible (build 8) | TH_0605 | - | 1e-173 | 76.74% (374) | alcohol dehydrogenase B |
| M. ulcerans Agy99 | MUL_0470 | adhB | 1e-130 | 58.29% (374) | zinc-containing alcohol dehydrogenase NAD- dependent AdhB |
| M. vanbaalenii PYR-1 | Mvan_5164 | - | 1e-132 | 59.73% (375) | alcohol dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0217|M.smegmatis_MC2_155 ---------MKTKGALLWELNSPFKVDEIDLGDPVADEVQIRLHAAGMCH
TH_0605|M.thermoresistible__bu ---------MKTKGALLWELNSPFRVDEIDVGDPVEDEVQIRLHAAGMCH
MAB_4560|M.abscessus_ATCC_1997 MYLEGLAESMKTKGALIRELNKPIVVEEITFGDPAEGEVQVQLHAAGMCH
MMAR_4935|M.marinum_M ---------MKTKGALIWEFNQPWSVEDIEIGDPVKDEVKIQMEAAGMCR
MUL_0470|M.ulcerans_Agy99 ---------MKTKGALIWEFNQPWSVEDIEIGDPVKDEVKIQMEAAGMCR
MAV_0705|M.avium_104 ---------MKTKGALIWEFNQPWSIEEIEIGDPQAHEVKIQMEAAGMCH
Mb0784c|M.bovis_AF2122/97 ---------MKTKGALIWEFNQPWSVEEIEIGDPRKDEVKIQMEAAGMCR
Rv0761c|M.tuberculosis_H37Rv ---------MKTKGALIWEFNQPWSVEEIEIGDPRKDEVKIQMEAAGMCR
Mflv_1593|M.gilvum_PYR-GCK ---------MKTKGALIWEFNQPWSIEEIEIGDPVKDEVKIQMEASGMCH
Mvan_5164|M.vanbaalenii_PYR-1 ---------MKTKGALIWEFNQPWTIEEIEIGDPVKDEVKIQMEASGMCH
MLBr_01784|M.leprae_Br4923 -------MSQTVRGVISRKKDEPVELVDIVIPDPGPGEAVVDVTACGVCH
..:*.: : :.* : :* . ** *. : : *.*:*:
MSMEG_0217|M.smegmatis_MC2_155 SDYHITTGATPIG-LPALGGHEGAGVVTKVGKNVTGIEEGDHVILAFIPA
TH_0605|M.thermoresistible__bu SDYHLTTGATPIG-LPALGGHEGAGVITKVGKNVTGLQEGDHVILAFIPS
MAB_4560|M.abscessus_ATCC_1997 SDYHVLTGATPME-LPVLPGHEGAGVVTKVGKGVTSVQEGDHVIFAFIPA
MMAR_4935|M.marinum_M SDNHLVTGGIPMAGFPVLGGHEGAGVVTEVGPGVDDIAPGDHVVLSFIPS
MUL_0470|M.ulcerans_Agy99 SDNHLVTGGIPMAGFPVLGGHEGAGVVTEVGPGVDDIAPGDHVVLSFIPS
MAV_0705|M.avium_104 SDHHLVTGGIPMAGFPVLGGHEGAGIVTEVGPGVEDIAPGDHVVLSFIPS
Mb0784c|M.bovis_AF2122/97 SDHHLVTGDIPMAGFPVLGGHEGAGIVTEVGPGVDDFAPGDHVVLAFIPS
Rv0761c|M.tuberculosis_H37Rv SDHHLVTGDIPMAGFPVLGGHEGAGIVTEVGPGVDDFAPGDHVVLAFIPS
Mflv_1593|M.gilvum_PYR-GCK SDHHLVTGDIPMAGFPVLGGHEGAGIVTEVGPGVEGLEPGDHVVLSFIPS
Mvan_5164|M.vanbaalenii_PYR-1 SDHHLVTGDIPMAGFPVLGGHEGAGVVTEVGPGVEGLEPGDHVVLSFIPS
MLBr_01784|M.leprae_Br4923 TDLTYREGGINDR-YPFLLGHEAAGTVEVVGPGVTAVEPGDFVILNWRAV
:* * * * ***.** : ** .* . **.*:: : .
MSMEG_0217|M.smegmatis_MC2_155 CGECPPCLKGFRSLCDRGAVLLGGKAIADGTSRIHAG-SHEVSPMNLLGT
TH_0605|M.thermoresistible__bu CGQCQPCLRGHRSLCDRGAVLLGGKAIADGTSRVRAG-STEVSPMNLLGT
MAB_4560|M.abscessus_ATCC_1997 CGKCPPCMRGYRSLCDRGAILLGGKAIADGTNRIHAG-NTPVSAMNLLGT
MMAR_4935|M.marinum_M CGRCPTCQAGLRNLCDLGAGLLAGAAVSDGTFRIQAR-GQNVYPMTLLGT
MUL_0470|M.ulcerans_Agy99 CGRCPTCQAGLRNLCDLGAGLLAGAAVSDGTFRIQAR-GQNVYPMTLLGT
MAV_0705|M.avium_104 CGSCPTCQAGMRNLCDLGAGLLGGEAVSDGTFRIQAR-GQNVYPMTLLGT
Mb0784c|M.bovis_AF2122/97 CGKCPSCQAGMRNLCDLGAGLLAGESVTDGSFRIQAR-GQNVYPMTLLGT
Rv0761c|M.tuberculosis_H37Rv CGKCPSCQAGMRNLCDLGAGLLAGESVTDGSFRIQAR-GQNVYPMTLLGT
Mflv_1593|M.gilvum_PYR-GCK CGACPSCQAGLRNLCDLGAMLLQGTAVSDNTHRIHAADGTPVIPMTLLGT
Mvan_5164|M.vanbaalenii_PYR-1 CGSCPSCQAGMRNLCDLGAMLLQGTAVSDNTHRIHAKDGTPVIPMTLLGT
MLBr_01784|M.leprae_Br4923 CGQCRACKRGRPSYCFDTFNAQQKMTLIDG---------TELTPALGIGA
** * .* * . * :: *. : . :*:
MSMEG_0217|M.smegmatis_MC2_155 FAPYMTVHKDSVVKIDKDIPFETAAIMGCAVPTGFGSATNVAQVQAGETV
TH_0605|M.thermoresistible__bu FAPYMTVHKDSVVKIDPEVPFETAAIMGCAVPTGFGSATNVAQVQPGETV
MAB_4560|M.abscessus_ATCC_1997 FSPYAVVHEDSVVKIDDDVPFESAALLGCAVPTGFGSSTNIAEVKPGEDV
MMAR_4935|M.marinum_M FSPYMVVHRSSVVKIDPAIPFEVAALVGCGVTTGYGSAVRTADVRPGDDV
MUL_0470|M.ulcerans_Agy99 FSPYMVVHRSSVVKIDPAIPFEVAALVGCGVTTGYGSAVRTADVRPGDDV
MAV_0705|M.avium_104 FSPYMVVHRSSVVKIDPSIPFEVAALVGCGVTTGYGSAVRTADIRPGQDV
Mb0784c|M.bovis_AF2122/97 FSPYMVVHRSSVVKIDPSVPFEVACLVGCGVTTGYGSAVRTADVRPGDDV
Rv0761c|M.tuberculosis_H37Rv FSPYMVVHRSSVVKIDPSVPFEVACLVGCGVTTGYGSAVRTADVRPGDDV
Mflv_1593|M.gilvum_PYR-GCK FSPYMVVHKSSVVKIDPSIPFEVACLVGCGVTTGYGSAVRSADVRPGDDV
Mvan_5164|M.vanbaalenii_PYR-1 FSPYMVVHKSSVVKIDPSIPFEVACLVGCGVTTGYGSAVRSANVRPGDDV
MLBr_01784|M.leprae_Br4923 FADKTLVHSGQCTKVDPAADPAVAGLLGCGVMAGLGAAINTAAVSRDDTV
*: ** .. .*:* * ::**.* :* *:: . * : .: *
MSMEG_0217|M.smegmatis_MC2_155 IIVGVGGIGMSALQGAVISGAKQVIAIDPNEWKREQAVKFGATHVYPTMA
TH_0605|M.thermoresistible__bu VIVGVGGIGLSALQGAVISGAKHVIAIDPVEFKRDTALKFGATHVFSSMA
MAB_4560|M.abscessus_ATCC_1997 IIVGIGGIGMSALQGAVVSGARRVIAIDPVPWKREQALKFGATHAFPTMA
MMAR_4935|M.marinum_M AIVGLGGVGMAALQGAVTAGARYIFAVEPVEWKRDQALKFGATHVYPDME
MUL_0470|M.ulcerans_Agy99 AIVGLGGVGMAALQGAVTAGARYIFAVEPVEWKRDQALKFGATHVYPDME
MAV_0705|M.avium_104 AIVGVGGVGMAALQGAVNAGARYIFAIDPVEWKRDQALKFGATHVYPDIM
Mb0784c|M.bovis_AF2122/97 AIVGLGGVGMAALQGAVSAGARYVFAVEPVEWKRDQALKFGATHVYPDIN
Rv0761c|M.tuberculosis_H37Rv AIVGLGGVGMAALQGAVSAGARYVFAVEPVEWKRDQALKFGATHVYPDIN
Mflv_1593|M.gilvum_PYR-GCK VIAGIGGVGMGALQGALNAGARNIFAIDPVEWKRDQALKFGATHAYPDIF
Mvan_5164|M.vanbaalenii_PYR-1 VIAGIGGVGMGALQGALNAGARTIFAIDPVEWKRDQALKFGATHAYPDIF
MLBr_01784|M.leprae_Br4923 AVIGCGGVGDAAISGAALVGANRIIAVDIDDTKLEWARTFGATHTVNALE
: * **:* .*:.** **. ::*:: * : * .*****. :
MSMEG_0217|M.smegmatis_MC2_155 EAIAP-VIDVTHGLMADKVIIAVGEMKGEYIEEALILTAKTGTCVVTGMG
TH_0605|M.thermoresistible__bu EAINP-VLELTHGFMAEKTIIAVGEMRGEYIEEAMTLTAKTGTCVVTGMG
MAB_4560|M.abscessus_ATCC_1997 EALLP-VMDLTWGIMAQKTIITVGEMRGEMIEEAMLLTAKTGTCVVTGMG
MMAR_4935|M.marinum_M AALMG-IAEVTYGLMAKKVVITVGELQGSDIDTYLAITSKGGTCVVTAIG
MUL_0470|M.ulcerans_Agy99 AALMG-IAEVTYGLMAKKVMITVGELQGSDIDTYLAITSKGGTCVVTAIG
MAV_0705|M.avium_104 AAMAG-MAEVTYGLMAHKVVVTVGELQGADVDNYLNITQKGGTCVLTAIG
Mb0784c|M.bovis_AF2122/97 AALMG-IAEVTYGLMAQKVIITVGKLDGADVDSYLTITAKGGTCVLTAIG
Rv0761c|M.tuberculosis_H37Rv AALMG-IAEVTYGLMAQKVIITVGKLDGADVDSYLTITAKGGTCVLTAIG
Mflv_1593|M.gilvum_PYR-GCK SAMAG-VAELTQGRMAAKTIITTGELHGEEIDNYLNITSKGGTCVVTAVA
Mvan_5164|M.vanbaalenii_PYR-1 SAMAG-VAEVTQGRMASKTIITTGELHGEEIDNYLNITAKGGTCVVTAVA
MLBr_01784|M.leprae_Br4923 LEVVKTIQDLTSGFGVDVVIDTVGRP--ETWKQAFYARDLAGTVVLVGVP
: : ::* * . .: :.*. . : ** *:..:
MSMEG_0217|M.smegmatis_MC2_155 AMTDVDVKLNLFLFTMLQKTLKGNIFGGGSSHIETPRLAALYKSGLLNID
TH_0605|M.thermoresistible__bu AMTDVDVKLNLFLFTMLQKTLKGNIFGGGSSHVETPRLVALYKSGLLKID
MAB_4560|M.abscessus_ATCC_1997 AMVDVDVKFNLFLFTMLQKTLKGNIFGGGTTHTETPRLVGLYKQGLLKID
MMAR_4935|M.marinum_M SLLDTQVNLNLAMLTLMQKNLQGTIFGGGNPQYDIPQLLSMYKARKLNID
MUL_0470|M.ulcerans_Agy99 SLLDTQVNLNLAMLTLMQKNLQGTIFGGGNPQYDIPHLLSMYKARNLNID
MAV_0705|M.avium_104 SLLDTNVTLNLAMLTLMQKNLQGTIFGGGNPQYDIPQLLSMYKAGKLNLD
Mb0784c|M.bovis_AF2122/97 SLVDTQVTLNLAMLTLLQKNIQGTIFGGGNPHYDIPKLLSMYKAGKLNLD
Rv0761c|M.tuberculosis_H37Rv SLVDTQVTLNLAMLTLLQKNIQGTIFGGGNPHYDIPKLLSMYKAGKLNLD
Mflv_1593|M.gilvum_PYR-GCK NMAKSDVTLNLSMLTLLQKNLQGTIFGGGNPHHDIPQLLSMYKAGRLNLD
Mvan_5164|M.vanbaalenii_PYR-1 NMASSEVTMNLSMLTLLQKNLQGTIFGGGNPHHDIPQLLSMYKAGRLNLD
MLBr_01784|M.leprae_Br4923 -TPDMRLDMPLLDFFSHGGSLKSSWYGDCLPERDFPTLVDLYLQGRLPLG
. : : * : .::.. :*. .. : * * :* * :.
MSMEG_0217|M.smegmatis_MC2_155 DMVTRTYKLEDINSGYQDMLDGKNIRGVIKYDESDW
TH_0605|M.thermoresistible__bu EMVTNTYRLEDINQGYQDMLDGKNIRGVIVYDESDW
MAB_4560|M.abscessus_ATCC_1997 EMITSTYSLEQINEGYQDMLDGKNIRGVIKYTEADW
MMAR_4935|M.marinum_M DMITRQYRLEQINEGYQDMIDGKNIRGVIRFTDADR
MUL_0470|M.ulcerans_Agy99 DMITRQYRLEQINEGYQDMIDGKNIRGVIRFTDADR
MAV_0705|M.avium_104 DMITRQYRLEQINDGYQDMLDGKNIRGVIRYTDADR
Mb0784c|M.bovis_AF2122/97 DMVTTAYKLEQINDGYQDMLNGKNIRGVIRYTDDDR
Rv0761c|M.tuberculosis_H37Rv DMVTTAYKLEQINDGYQDMLNGKNIRGVIRYTDDDR
Mflv_1593|M.gilvum_PYR-GCK DMVTRQYKLEQINDGYKDMLEGKNIRGVIRYTDADR
Mvan_5164|M.vanbaalenii_PYR-1 DMVTRQYKLEQINEGYKDMLEGKNIRGVIRYTDADR
MLBr_01784|M.leprae_Br4923 KFVSERIGLGDVEEAFHKIHGGKVLRSVVML-----
.::: * :::..::.: ** :*.*: