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M. thermoresistible (build 8) TH_1155 (-)

annotation: trehalose 6-phosphate phosphorylase
coordinates: 2231586 - 2234528
length: 981

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1155--100% (981)trehalose 6-phosphate phosphorylase
M. thermoresistible (build 8)TH_2141-7e-4726.93% (776) CONSERVED HYPOTHETICAL PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2029otsB10.058.79% (961) trehalose-6-phosphate phosphatase OtsB1
M. gilvum PYR-GCKMflv_4989-0.053.63% (1061) HAD family hydrolase
M. tuberculosis H37RvRv2006otsB10.058.79% (961) trehalose-6-phosphate phosphatase OtsB1
M. leprae Br4923MLBr_00392-2e-4727.00% (789) putative sugar phosphorylase
M. abscessus ATCC 19977-----
M. marinum MMMAR_2257otsB10.069.30% (961) trehalose-6-phosphate phosphatase OtsB1
M. avium 104MAV_4352-3e-5128.44% (777) glycoside hydrolase family protein 65, central catalytic
M. smegmatis MC2 155MSMEG_3954-0.061.74% (860) trehalose 6-phosphate phosphorylase
M. ulcerans Agy99MUL_0906-5e-3727.60% (558) glycosyl hydrolase
M. vanbaalenii PYR-1Mvan_4107-0.070.49% (881) HAD family hydrolase

CLUSTAL 2.0.9 multiple sequence alignment


TH_1155|M.thermoresistible__bu      --------------------------------------------------
MMAR_2257|M.marinum_M               ----------MKSFTIDPRRHDGVIFVLD---------------------
Mvan_4107|M.vanbaalenii_PYR-1       ---------MKLPVTIDPRYHDAVLLDLD---------------------
Mb2029|M.bovis_AF2122/97            MRCGIVVNVTGPPPTIDRRYHDAVIVGLDNVVDKATRVHAAAWTKFLDDY
Rv2006|M.tuberculosis_H37Rv         MRCGIVVNVTGPPPTIDRRYHDAVIVGLDNVVDKATRVHAAAWTKFLDDY
MSMEG_3954|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_4989|M.gilvum_PYR-GCK          -----------MPVFIDPRHHDAVIFEVD---------------------
MLBr_00392|M.leprae_Br4923          --------------------------------------------------
MUL_0906|M.ulcerans_Agy99           --------------------------------------------------
MAV_4352|M.avium_104                --------------------------------------------------
                                                                                      

TH_1155|M.thermoresistible__bu      --------------------------------------------------
MMAR_2257|M.marinum_M               --------------------------------------------------
Mvan_4107|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2029|M.bovis_AF2122/97            LTRRPQRTGEDHCPLTHDDYRRFLAGKPDSVADFLAARGIRLPPGSPTDL
Rv2006|M.tuberculosis_H37Rv         LTRRPQRTGEDHCPLTHDDYRRFLAGKPDGVADFLAARGIRLPPGSPTDL
MSMEG_3954|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_4989|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_00392|M.leprae_Br4923          --------------------------------------------------
MUL_0906|M.ulcerans_Agy99           --------------------------------------------------
MAV_4352|M.avium_104                --------------------------------------------------
                                                                                      

TH_1155|M.thermoresistible__bu      --------------------------------------------------
MMAR_2257|M.marinum_M               -----------------GDGHEQS-IWEPTVALARKLWQVGVGTAVYSPT
Mvan_4107|M.vanbaalenii_PYR-1       -----------------GALTSEAPLFGPTVDLARKLQSIGVAAAAYSSN
Mb2029|M.bovis_AF2122/97            TDDTVYGLQNLERQTFLQLLNTGVPEGKSIASFARRLQVAGVRVAAHTSH
Rv2006|M.tuberculosis_H37Rv         TDDTVYGLQNLERQTFLQLLNTGVPEGKSIASFARRLQVAGVRVAAHTSH
MSMEG_3954|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_4989|M.gilvum_PYR-GCK          -----------------DPVADEVALSASQGDLARRLTAAGIGVGCAES-
MLBr_00392|M.leprae_Br4923          --------------------------------------------------
MUL_0906|M.ulcerans_Agy99           --------------------------------------------------
MAV_4352|M.avium_104                --------------------------------------------------
                                                                                      

TH_1155|M.thermoresistible__bu      --------------------------------------------------
MMAR_2257|M.marinum_M               DESVRVLDAAGLSEPEQVSAP----PQASR-AKPYCVGLSAAAAKLGAAV
Mvan_4107|M.vanbaalenii_PYR-1       GQCRQALKAAGIDDLFGVCIDGMEGDRGTA-EKPDPAVLLEAARRIGARP
Mb2029|M.bovis_AF2122/97            RNYGHTLDATGLAEVFAVFVDGAVTAELGLPAEPNPAGLIETAKRLGANP
Rv2006|M.tuberculosis_H37Rv         RNYGHTLDATGLAEVFAVFVDGAVTAELGLPAEPNPAGLIETAKRLGANP
MSMEG_3954|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_4989|M.gilvum_PYR-GCK          ------------------------------------AMLRETARRLGVHP
MLBr_00392|M.leprae_Br4923          --------------------------------------------------
MUL_0906|M.ulcerans_Agy99           --------------------------------------------------
MAV_4352|M.avium_104                --------------------------------------------------
                                                                                      

TH_1155|M.thermoresistible__bu      --------------------------------------------------
MMAR_2257|M.marinum_M               QRLAVVAGMDGGVEAARECGFAFVIGFDRDGRAEELLRRGADVVAADLAE
Mvan_4107|M.vanbaalenii_PYR-1       QRCVVVENSAAGVAAGRAGGFALVVGIDGTEVADELTRHGADVVLAGLAD
Mb2029|M.bovis_AF2122/97            GRCVVIDSCQTGLRAGRNGGFALVIAVDAHGDAENLLSSGADAVVADLAA
Rv2006|M.tuberculosis_H37Rv         GRCVVIDSCQTGLRAGRNGGFALVIAVDAHGDAENLLSSGADAVVADLAA
MSMEG_3954|M.smegmatis_MC2_155      --------------------------------MEHHTDAAQDDVVTD---
Mflv_4989|M.gilvum_PYR-GCK          GRCVVVAGGEAGVRTARAGGFALIVGIDRAERAEDLRSCGADVVVPDLVA
MLBr_00392|M.leprae_Br4923          --------------------------------------------------
MUL_0906|M.ulcerans_Agy99           --------------------------------------------------
MAV_4352|M.avium_104                --------------------------------------------------
                                                                                      

TH_1155|M.thermoresistible__bu      ------------LSNALASYGLLIGIVANRQPVVFCRFDGAL----ADRD
MMAR_2257|M.marinum_M               VTVRTGDERLSQCPNALDSYGQVIGMVAGRQLFVCMDYDGTLSEIVSEPD
Mvan_4107|M.vanbaalenii_PYR-1       IAVRTGDRRISELPNALASYGQLIGITSARESMLFLDYDGTLSPIVSDPA
Mb2029|M.bovis_AF2122/97            VTVGSGDAAISTIPDALQVYSQLKRLLTGRRPAVFLDFDGTLSDIVERPE
Rv2006|M.tuberculosis_H37Rv         VTVGSGDAAISTIPDALQVYSQLKRLLTGRRPAVFLDFDGTLSDIVERPE
MSMEG_3954|M.smegmatis_MC2_155      ---DEDRRPIADLPDALDHFDEIRDLLAFRNPAS----------------
Mflv_4989|M.gilvum_PYR-GCK          VTVRDGYRRMSELADALQSYGEIVPLAETRTPVVLLDFDGTLSDIVGDPD
MLBr_00392|M.leprae_Br4923          --------------------------------------------------
MUL_0906|M.ulcerans_Agy99           --------------------------------------------------
MAV_4352|M.avium_104                --------------------------------------------------
                                                                                      

TH_1155|M.thermoresistible__bu      TATLVDGAAAALRKLASLCPVAVISGREVSELRARVGVDGLWYAGGHGRE
MMAR_2257|M.marinum_M               AATLVDGAAEALAHLSTQCPVAILSGRDLTDIRDRVGVPGIWYAGSHGFE
Mvan_4107|M.vanbaalenii_PYR-1       AARLVEGADEALELVSKVCPVAILSGRDLADVSARVGTPGVWYAGSHGFE
Mb2029|M.bovis_AF2122/97            AATLVDGAAEALRALAAQCPVAVISGRDLADVRNRVKVDGLWLAGSHGFE
Rv2006|M.tuberculosis_H37Rv         AATLVDGAAEALRALAAQCPVAVISGRDLADVRNRVKVDGLWLAGSHGFE
MSMEG_3954|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_4989|M.gilvum_PYR-GCK          TAALVPGARSVLDALAARCPVAVVSGRALADIRDRIGVPGIWYAGSHGFE
MLBr_00392|M.leprae_Br4923          --------------------------------------------------
MUL_0906|M.ulcerans_Agy99           --------------------------------------------------
MAV_4352|M.avium_104                --------------------------------------------------
                                                                                      

TH_1155|M.thermoresistible__bu      VVAPDGSHHRFDG-------------------------------------
MMAR_2257|M.marinum_M               LIAPDGTHHQHEAAAAAVDVLASAAKDLRHELAQIPGVSVEHKRFGVAVH
Mvan_4107|M.vanbaalenii_PYR-1       LTSPDGAYHCNDAAAVFVPVLEEAAAELNKTLAQIAGVRVEHKRFAVAVH
Mb2029|M.bovis_AF2122/97            LVAPDGSHHQNAAATAAIDGLAEAAAQLADALREIAGAVVEHKRFAVAVH
Rv2006|M.tuberculosis_H37Rv         LVAPDGSHHQNAAATAAIDGLAEAAAQLADALREIAGAVVEHKRFAVAVH
MSMEG_3954|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_4989|M.gilvum_PYR-GCK          LCSPDGGIQENEAGLEIVRVLAGALAEVRERVGAVDGVLIEDKRFSIAVH
MLBr_00392|M.leprae_Br4923          --------------------------------------------------
MUL_0906|M.ulcerans_Agy99           --------------------------------------------------
MAV_4352|M.avium_104                --------------------------------------------------
                                                                                      

TH_1155|M.thermoresistible__bu      ---------------------------------------TDWDPGAALTS
MMAR_2257|M.marinum_M               YRNVAREHVAQVIATTHRYRREYGLRVTSGRKVVELRPDIDWDKGAALAW
Mvan_4107|M.vanbaalenii_PYR-1       YREVAPEQVSEIVSATHQLGARRGLRVTSGRMLVELRPDLDWDKGTTLAW
Mb2029|M.bovis_AF2122/97            YRNVADDSVDNLIAAVRRLGHAAGLRVTTGRKVVELRPDIAWDKGKALDW
Rv2006|M.tuberculosis_H37Rv         YRNVADDSVDNLIAAVRRLGHAAGLRVTTGRKVVELRPDIAWDKGKALDW
MSMEG_3954|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_4989|M.gilvum_PYR-GCK          YRNVAAESVDEVVTAVRNIAQCNGLRADGGRRVVELKPDTGWHKGRAVEW
MLBr_00392|M.leprae_Br4923          --------------------------------------------------
MUL_0906|M.ulcerans_Agy99           --------------------------------------------------
MAV_4352|M.avium_104                --------------------------------------------------
                                                                                      

TH_1155|M.thermoresistible__bu      IRARMGR----PEPVLPIYVGSELADEAAFDVLRLDGVSVVVH-HLGAAD
MMAR_2257|M.marinum_M               IRSLIFE----DSRVLPMYVGDDLTDEDAFDALRFSGVGIVVR-HDEDGD
Mvan_4107|M.vanbaalenii_PYR-1       IRDRIDP----SGSLLPIYIGDDLTDEDAFDAVRFDGIGIVVG-HDEDGD
Mb2029|M.bovis_AF2122/97            IGERLGPAEVGPDLRLPIYIGDDLTDEDAFDAVRFTGVGIVVR-HNEHGD
Rv2006|M.tuberculosis_H37Rv         IGERLGPAEVGPDLRLPIYIGDDLTDEDAFDAVRFTGVGIVVR-HNEHGD
MSMEG_3954|M.smegmatis_MC2_155      ---------------LPVFIG-NPADDSAFRTVRRDGIGIVVVTHAEDEK
Mflv_4989|M.gilvum_PYR-GCK          ILDRIDG----DELLLPVYIGDDLTDEDGFDAVRLRGIGVAVR-SAESGD
MLBr_00392|M.leprae_Br4923          --------------------------------------------------
MUL_0906|M.ulcerans_Agy99           --------------------------------------------------
MAV_4352|M.avium_104                --------------------------------------------------
                                                                                      

TH_1155|M.thermoresistible__bu      RPTGAQFRLDGAEEVCEFLRRGGNWIAYQRQTSNEAWTFSYRGYDPRQEK
MMAR_2257|M.marinum_M               RPTAANFTLRNPNEVRDFVRRGAGWLAHAHETQSRGWTFTFEGYDPPNEK
Mvan_4107|M.vanbaalenii_PYR-1       RKTAANFTLQSPEQVREFIQRGSRWLAYKHQVSGEAWDYVFDGYDPQNEK
Mb2029|M.bovis_AF2122/97            RRSAATFRLECPYTVCQFLSQLACDLQEAVQHDDP-WTLVFHGYDPGQER
Rv2006|M.tuberculosis_H37Rv         RRSAATFRLECPYTVCQFLSQLACDLQEAVQHDDP-WTLVFHGYDPGQER
MSMEG_3954|M.smegmatis_MC2_155      RSTTATFRLDSPGAAATFRHRLAQEADRPTSIDPG-WVLTFDGYDPANER
Mflv_4989|M.gilvum_PYR-GCK          RRSAARFALDSPAAVCAFLARLSDQLAVEQDLTNDPWTLTFGGYLPEDER
MLBr_00392|M.leprae_Br4923          -------------------------MITEEAFPVEPWQIRETRLDLNLLA
MUL_0906|M.ulcerans_Agy99           --------------------------------------------------
MAV_4352|M.avium_104                -------------------------MIADESFPVDPWHVRETQLNLNLLA
                                                                                      

TH_1155|M.thermoresistible__bu      LREALCTVGNGYFATRGAAPEARAG--QVHYPGTYAAGVFNRLDDVVDGR
MMAR_2257|M.marinum_M               LREALCTVGNGYFATRGAAPESKAG--QVHYPGTYAGGVFNRLDDLIGGT
Mvan_4107|M.vanbaalenii_PYR-1       LREALCTVGNGYFATRGAAPESKAG--QVHYPGTYAAGVYNRLVDNVSGT
Mb2029|M.bovis_AF2122/97            LREALCAVGNGYLGSRGCAPESAES--EAHYPGTYVAGVYNQLTDHIEGC
Rv2006|M.tuberculosis_H37Rv         LREALCAVGNGYLGSRGCAPESAES--EAHYPGTYVAGVYNQLTDHIEGC
MSMEG_3954|M.smegmatis_MC2_155      FREALCTLGNGYFATRGCAPEAPAG--RFHYPGTYVAGIYNRLTDEIAGH
Mflv_4989|M.gilvum_PYR-GCK          LREALCTLGNGYLATRGAAPECDAS--RLHYPATYVAGIYNRLFDEIAGT
MLBr_00392|M.leprae_Br4923          QSESLFALSNGHIGLRGNLDEGEPYGLPGTYLNSFYEIRPLPYAEAGYGY
MUL_0906|M.ulcerans_Agy99           --------------------------------------------------
MAV_4352|M.avium_104                QSESLFTLSNGHIGLRGNLDEGEPYGLPGTYLNSFYEIRPLPYAEAGYGY
                                                                                      

TH_1155|M.thermoresistible__bu      VTAHESMVNLPNWLPLTFRIEGGPWFDVDAVTLLDYRQTLDLRGAVLTRE
MMAR_2257|M.marinum_M               RTAHESLVNLPNWLPLTFRIDGGDWFDVDAVTLLSYRQTLDLRGAVLTRE
Mvan_4107|M.vanbaalenii_PYR-1       EIDNESLVNLPNWLALTFRVDHGDWFDIDAVTVLSYRQTLDLRGAVLTRQ
Mb2029|M.bovis_AF2122/97            TVDNESLVNLPNWLSLTFRIDGGAWFNVDTVELLSYRQTFDLRRATLTRS
Rv2006|M.tuberculosis_H37Rv         TVDNESLVNLPNWLSLTFRIDGGAWFNVDTVELLSYRQTFDLRRATLTRS
MSMEG_3954|M.smegmatis_MC2_155      RTDNESLVNLPNWLALTFRFDDGPWLDVDDTDLQSYQQTLDLRRGVLTRQ
Mflv_4989|M.gilvum_PYR-GCK          TVDNESLVNLPNWLPVTFRVDGGAWFDIDAVEFTSYVTTLDLRRATLTRE
MLBr_00392|M.leprae_Br4923          PEAGQTVVDVTNGKILRLFVED-EPFDVRYGEVIFHERVLDLCAGTLTRR
MUL_0906|M.ulcerans_Agy99           --------------------------------------------------
MAV_4352|M.avium_104                PEAGQTLVDVTNGKIIRLLVED-EPFDVRYGELLSHERTLDLRGGTLTRS
                                                                                      

TH_1155|M.thermoresistible__bu      LRFRDNAGRTTSVTQQRFVAMHTAHIAALETTLVAEDWSGTVDVRSTLDG
MMAR_2257|M.marinum_M               LTFRDDAGRTSSVTQHRFVSMNQAHVAALQTTIVGHDWSGTIEIRSTIDG
Mvan_4107|M.vanbaalenii_PYR-1       VRFRDHAGRTSSLTQRRFVAMHLPHAGALETTVVAEDWSGTIEFRSTVDG
Mb2029|M.bovis_AF2122/97            LRFRDAGGRVTTMTQERFASMNRPNLVALQTRIESENWSGTVDFRSLVDG
Rv2006|M.tuberculosis_H37Rv         LRFRDAGGRVTTMTQERFASMNRPNLVALQTRIESENWSGTVDFRSLVDG
MSMEG_3954|M.smegmatis_MC2_155      FRFCDKAGRVATVTQHRLVAMHLPHLAMLQTMVTAENFSGTVEFRSEIDG
Mflv_4989|M.gilvum_PYR-GCK          FVMRDQAGRITRIRQRRLVAMHRPHVAAMATTVRAENWSGRLQLRSVLDG
MLBr_00392|M.leprae_Br4923          ANWRSPADKQVKVVSTRLVSLAHRSVAAIEYVVEALDKFVRVTVQSELVS
MUL_0906|M.ulcerans_Agy99           --------------------------------MEAVDDFARITVQSELVT
MAV_4352|M.avium_104                AYWRSPAGKEVKVVSTRLVSLAQRGVAAIEYVVQAVGDFVRVTVQSELVT
                                                                    : . .    : .:* :  

TH_1155|M.thermoresistible__bu      DVRNGLVERYRDLRGDHLESLGKSALTGD--SVLLSVRTNQSRIPIAMAA
MMAR_2257|M.marinum_M               NVRNSGVERYRNLASNHLQGLQKAVLSEN--SVSMAVETTQSKIPVAVAA
Mvan_4107|M.vanbaalenii_PYR-1       NVTNSLVERYRDLANEHLDSADTQELSNN--SVLLTMQTNQSRIPIAMAA
Mb2029|M.bovis_AF2122/97            GVHNTLVDRYRQLSSQHLT-TAEIEVLAD--SVLLRTQTSQSGIAIAVAA
Rv2006|M.tuberculosis_H37Rv         GVHNTLVDRYRQLSSQHLT-TAEIEVLAD--SVLLRTQTSQSGIAIAVAA
MSMEG_3954|M.smegmatis_MC2_155      AVTNSLVERYRDLSNVHLVGHEKRSLTAD--SLLLTAHTCQSHIRVAVAL
Mflv_4989|M.gilvum_PYR-GCK          GVENLGVERYRALSSRHLTVDAMRELSRD--AVLLQTHTGESQIQIAVAA
MLBr_00392|M.leprae_Br4923          NEDQPETSGDPRVSAILDNPLEAVEHEATERGGLLMHRTRASSLMMAAGM
MUL_0906|M.ulcerans_Agy99           NEDQPETSDDPRVSAILEHPLQAVDHENTECGALLMHRTRSSALMMAAAM
MAV_4352|M.avium_104                NEDQPQTSGDPRVSAILENPLEEVDHENTDTGALLIHRTRSSALMMAAGM
                                       :  ..    :                  .  :  .*  * : :* . 

TH_1155|M.thermoresistible__bu      RTTAWRDGDPVSAGYRLVDEESEIGHQITTGLSRGQRLTVEKVVALSTG-
MMAR_2257|M.marinum_M               RTSLWRADEPVAATYRLLDEEFEIGHEIFTEAKLGQPLTVEKIVTLVSG-
Mvan_4107|M.vanbaalenii_PYR-1       RNTVWRDGEPVPAAFALFDQGAEIGHDIAVHLSAGDAVTLEKVVTVYTG-
Mb2029|M.bovis_AF2122/97            RSTLWRDGQRVDAQYRVARDTNRGGHDIQVTLSAGQSVTLEKVATIFTS-
Rv2006|M.tuberculosis_H37Rv         RSTLWRDGQRVDAQYRVARDTNRGGHDIQVTLSAGQSVTLEKVATIFTS-
MSMEG_3954|M.smegmatis_MC2_155      RNTVWRGDSPARADYTLVDDRRRAGHVISCYIEAGQPVTLEKAVSVATS-
Mflv_4989|M.gilvum_PYR-GCK          RHRVT-GGEPESVDQRVFRDDCRIGHDIEVVVTAGQAVTLEKVIAVYTG-
MLBr_00392|M.leprae_Br4923          DHEVEVPGRVEITTDARPDLAR---TTVICGLRPGQKLRIVKYLAYGWSS
MUL_0906|M.ulcerans_Agy99           DHEVEVPGRVEITTDARPDLAR---TTVICGLRPGQKLRIVKYLAYGWSS
MAV_4352|M.avium_104                DHEVEVPGRVEVSTDSRADLAR---TTVICGLRAGQKLRIVKYLAYGWSS
                                           .                   :      *: : : *  :   . 

TH_1155|M.thermoresistible__bu      -RDVGSSEPSESAERILERQGRFGEIRAAHTVAWAHLWRRLSIEFEDHTD
MMAR_2257|M.marinum_M               -LDVATSHPAIGAERRLGRQGRFAEICDAHRIAWSHLWERLSIEFSNHTE
Mvan_4107|M.vanbaalenii_PYR-1       -RDVAISEPGVNAQRWVTRLGRFDELLDGHRTAWTHLWERLSIDFDDFTD
Mb2029|M.bovis_AF2122/97            -RDAATLTAAISAQRCLGEAGRYAELCQQHVRAWARLWERCAIDLTGNTE
Rv2006|M.tuberculosis_H37Rv         -RDAATLTAAISAQRCLGEAGRYAELCQQHVRAWARLWERCAIDLTGNTE
MSMEG_3954|M.smegmatis_MC2_155      -RDHATCEAANEATRRLQWVDRYHDVQQAHTTAWGQLWERFDVDIGGRTD
Mflv_4989|M.gilvum_PYR-GCK          -RDHGMSGPVTAAEREIAGADTFDRLEDGHRLAWAHLWERFNIDMGHDPN
MLBr_00392|M.leprae_Br4923          LRSRPALHDQATAALHTARYSGWQGLLDAQRAYLNEFWDSADVEVEGDPE
MUL_0906|M.ulcerans_Agy99           LRSRPALRDQVAGALHGARYSGWQGLIDTQRSYLDEFWDSADVEVEGDPE
MAV_4352|M.avium_104                MRSRPALRDQVAAALHSARYTGWPGLLESQRKYLDNFWDCADVEVEGDPE
                                      .         .         :  :   :     .:*    ::.   .:

TH_1155|M.thermoresistible__bu      ELRVMRLHLLHLLQTVSPHSADLDIGPPARGLHGEAYRGHIFWD-ELFIF
MMAR_2257|M.marinum_M               ELRVLRLHLLHLLQTVSYNSADLDVGVPARGLHGEAYRGHIFWD-ELFIF
Mvan_4107|M.vanbaalenii_PYR-1       ELRILRLHLLHLLQTVSLNTADLDAGVPARGLHGEAYRGHIFWD-ELFIF
Mb2029|M.bovis_AF2122/97            ELRLVRLHLLHLLQTISPHTAELDAGVPARGLNGEAYRGHVFWD-ALFVA
Rv2006|M.tuberculosis_H37Rv         ELRLVRLHLLHLLQTISPHTAELDAGVPARGLNGEAYRGHVFWD-ALFVA
MSMEG_3954|M.smegmatis_MC2_155      ELRTVRLHLLHTLQTLSPHVRDLDIGVPARGLTGEAYRGHIFWD-ELFVA
Mflv_4989|M.gilvum_PYR-GCK          LLRLVRLHQLHLLQTLSPHTADLDVGVPARGLHGEAYRGHVFWD-ELFVF
MLBr_00392|M.leprae_Br4923          SQQAVRFGLFHLLQAS---ARAERRAIPSKGLTGTGYDGHAFWDTEGFVL
MUL_0906|M.ulcerans_Agy99           CQQAVRFGLFHLLQAS---ARAERRAIPSKGLTGTGYDGHAFWDSEGFVL
MAV_4352|M.avium_104                SQQAVRFGLFHLLQAS---ARAERRAIAAKGLTGTGYDGHAFWDTEGYVL
                                      : :*:  :* **:          . .::** * .* ** ***   :: 

TH_1155|M.thermoresistible__bu      PVLNLRFPMITRSLLQYRYRRLPEARRAARLAGYRGAIFPWQSGSDGREE
MMAR_2257|M.marinum_M               PVLNLRLPAVTRSLLLYRYRRLLEAQRAAKLAGYRGAMYPWQSGSDGREE
Mvan_4107|M.vanbaalenii_PYR-1       PVLNLRAPMITRSLLGYRYRRLPEARHAARAAGHSGAMFPWQSGSDGREE
Mb2029|M.bovis_AF2122/97            PVLSLRMPKVARSLLDYRYRRLPAARRAAHRAGHLGAMYPWQSGSDGSEV
Rv2006|M.tuberculosis_H37Rv         PVLSLRMPKVARSLLDYRYRRLPAARRAAHRAGHLGAMYPWQSGSDGSEV
MSMEG_3954|M.smegmatis_MC2_155      PVVSLRRPALTRALLAYRHRRLPEARRAARDAGFTGAMFPWQSGSNGREE
Mflv_4989|M.gilvum_PYR-GCK          PVLNMRLPKVTRSLLLYRYRRLPEARRAAAEAGYAGAMFPWQSGSDGREE
MLBr_00392|M.leprae_Br4923          PVLTYTAPHAVADALRWRASTLQLAKDRAAELGLDGASFCWR--------
MUL_0906|M.ulcerans_Agy99           PVLTYTAPHAVADALRWRASTLDLAKERAAELGLDGASFPWR--------
MAV_4352|M.avium_104                PVLTYTAPHTVADALRWRASTLDLAKERAAELGLEGAAFPWR--------
                                    **:.   *  .   * :*   *  *:  *   *  ** : *:        

TH_1155|M.thermoresistible__bu      SPELHLNPRSGRWNSDPSHRAHHIGIAIAYNVWQFYQVTGDLAYLIDHGA
MMAR_2257|M.marinum_M               SPEQHLNPRSGRWIPDASHRAHHIGIAVAYNVWQFYQVTGDLAFMIDYGT
Mvan_4107|M.vanbaalenii_PYR-1       SQRLHLNPRSGRWNPDASARAHHIGIAVAYSAWKFYQVTGDLAYLIDYGA
Mb2029|M.bovis_AF2122/97            SQQLHLNPRSGRWTPDPSDRAHHVGLAVAYNAWHYYQVTGDRQYLVDCGA
Rv2006|M.tuberculosis_H37Rv         SQQLHLNPRSGRWTPDPSDRAHHVGLAVAYNAWHYYQVTGDRQYLVDCGA
MSMEG_3954|M.smegmatis_MC2_155      SPALHLNPRSGRWNPDPSALAHHVGLAVAYNIWQYYQVTDDLEYLIDYGA
Mflv_4989|M.gilvum_PYR-GCK          SQRLHLNPRSGRWNPDASARAHHVGLAIAFNIWQHYQVTGDIGFLIDYGA
MLBr_00392|M.leprae_Br4923          --TIRGQECSAYWP--AGTAAWHINADIAMAFERYRIVTGDHSLEEECGL
MUL_0906|M.ulcerans_Agy99           --TIRGEECSAYWP--AGTAAWQINADIAMAFERYRTVTCDHSLEKDCGL
MAV_4352|M.avium_104                --TIRGQECSAYWP--AGTAAWHINADIAMAFERYRIVTGDDDLEAECGL
                                        : :  *. *   ..  * ::.  :*    :.  ** *     : * 

TH_1155|M.thermoresistible__bu      ELLVEIARFWVSRAEFDTRRGRYRIRGVIGPDEFHAGYPDRPFDGVDDNA
MMAR_2257|M.marinum_M               EMMAEIARFWVSRATYDAERDRYHIKGVIGPDEFHSGYPDRPYDGVDDNA
Mvan_4107|M.vanbaalenii_PYR-1       ELIAEVARFFVSLASYDEDRERFGIKGVIGPDEFHSGYPEAPYDGIDNNA
Mb2029|M.bovis_AF2122/97            ELLVEIARFWVGLAKLDDSRGRYLIRGVIGPDEFHSGYPGNEYDGIDNNA
Rv2006|M.tuberculosis_H37Rv         ELLVEIARFWVGLAKLDDSRGRYLIRGVIGPDEFHSGYPGNEYDGIDNNA
MSMEG_3954|M.smegmatis_MC2_155      ETLLEIARFWAGLALFSRERGRYVIPGVIGPDEFHTGYPGRLYDGIDNNA
Mflv_4989|M.gilvum_PYR-GCK          EMLVEITKFWVSAANLDPHRDRYVIRGVIGPDEFHSGYPGREYDGVDNNA
MLBr_00392|M.leprae_Br4923          AVLIETARLWLSLGHHDR-HGVWHLDGVTGPDEYTA--------VVRDNV
MUL_0906|M.ulcerans_Agy99           AVLIETARLWISLGHHDR-HGIWHLDGVTGPDEYTA--------IVRDNV
MAV_4352|M.avium_104                PVLVETARLWLSLGHHDR-HGVWHLDGVTGPDEYTA--------VVRDNV
                                      : * :::: . .  .  :  : : ** ****: :         : :*.

TH_1155|M.thermoresistible__bu      YTNVMAVWVILRALEALNLIPLPNRIDVREKLNLTAAELAQWDDVSRRMY
MMAR_2257|M.marinum_M               YTNVMAAWVILRAIDALLLMPLPNRLDLYEKLALTEEELAQWDHVSRRMF
Mvan_4107|M.vanbaalenii_PYR-1       YTNVMAVWVIMRAIDALNLLPLPNRLDLLEALGLHNEELAHWDDVSRRMY
Mb2029|M.bovis_AF2122/97            YTNVMAVWVILRAMEALDLLPLTDRRHLIEKLGLTTQERDQWDDVSRRMF
Rv2006|M.tuberculosis_H37Rv         YTNVMAVWVILRAMEALDLLPLTDRRHLIEKLGLTTQERDQWDDVSRRMF
MSMEG_3954|M.smegmatis_MC2_155      YTNVMAVWVILRALDALDAMPLADRTALLERLGLHGDELDKWEDVSHRMF
Mflv_4989|M.gilvum_PYR-GCK          YTNLMAVWVIVRTLEALERLPLSYRLALLETVGVGDEDLAHWEDVSRRMF
MLBr_00392|M.leprae_Br4923          FTNLMAASNLITAADACLRQPE-----AAKAMGVTTEEMAAWRDAADAAN
MUL_0906|M.ulcerans_Agy99           FTNLMAAHNLITAADACLRHPE-----AAQDMGVTTEGMAAWRDAADAVN
MAV_4352|M.avium_104                FTNLMAAHNLRVAAEACNRHPD-----GAKALGVTTEETAAWRDAADAVK
                                    :**:**.  :  : :*    *        : : :       * ..:    

TH_1155|M.thermoresistible__bu      VPFHD--GIISQFEGYGELAELDWDGYRRRYGNIQRLDRILEAEGDDVNR
MMAR_2257|M.marinum_M               VPFHD--GVISQFDGYEQLAELDWDAYRQRYGNIQRLDRILEAEDDDVNR
Mvan_4107|M.vanbaalenii_PYR-1       VPFHD--GVISQFEGYGDLADLDWDRLRRQYGNIQRLDRILEAENDDVNR
Mb2029|M.bovis_AF2122/97            VPFHD--GVISQFEGYSELAELDWDHYRHRYGNIQRLDRILEAEGDSVNN
Rv2006|M.tuberculosis_H37Rv         VPFHD--GVISQFEGYSELAELDWDHYRHRYGNIQRLDRILEAEGDSVNN
MSMEG_3954|M.smegmatis_MC2_155      VPFHN--GVISQFEGYESLVELDWDRYRHEYGNIQRLDRILEAENDNVNR
Mflv_4989|M.gilvum_PYR-GCK          VPFHD--GVITQFEGYDRLRELDWEAYRNRYDDLQRLDRILEAEGDSVNN
MLBr_00392|M.leprae_Br4923          IPYDDELGVHQQCEGFTTFAEWDFEAN-------TTYPLFLHEAYVRLYP
MUL_0906|M.ulcerans_Agy99           IPYDEELGVHQQCEGFTTLAEWDFETN-------TTYPLLLHEAYVRLYP
MAV_4352|M.avium_104                IPYDSGLGVHQQCEGFTTFAEWDFEHN-------TTYPLLLHEAYVRLYP
                                    :*:..  *:  * :*:  : : *::              :*.     :  

TH_1155|M.thermoresistible__bu      YKASKQADALMLLYLLSADELRELLGHLGYRFTAEQIPGMVDYYLARTSH
MMAR_2257|M.marinum_M               YRASKQADALMLLYLLSADELGELLDRLGYHMERDQIPEMVDYYMARTSH
Mvan_4107|M.vanbaalenii_PYR-1       YKASKQADALMLLYLLSADELREILDRLGYRFLPEQVPKMVDYYLARTSH
Mb2029|M.bovis_AF2122/97            YQASKQADALMLLYLLSSDELIGLLARLGYRFAPTQIPGTVDYYLARTSD
Rv2006|M.tuberculosis_H37Rv         YQASKQADALMLLYLLSSDELIGLLARLGYRFAPTQIPGTVDYYLARTSD
MSMEG_3954|M.smegmatis_MC2_155      YKASKQADVLMLFYLLSADEIRELLARLGYRFTPKQIPETVDYYLSRTSH
Mflv_4989|M.gilvum_PYR-GCK          YRAGKQADTLMLFYLLSADELYELFDRLGYNFAPEQIPATIDYYQKRTSH
MLBr_00392|M.leprae_Br4923          AQVIKQADLVLAMQWQS------------HAFTPEQKARNVDYYERRMVR
MUL_0906|M.ulcerans_Agy99           TQVIKQAHLVLAMQWQS------------HAFTAEQKARNVDYYERRMVR
MAV_4352|M.avium_104                AQVIKQADLVLAMHWQS------------HAFTPEQKARNVDYYEPRMVR
                                     :. ***. :: :   *            : :   * .  :***  *   

TH_1155|M.thermoresistible__bu      GSTLSAVVHAWVLARA-NRDRAMEYFERVLKSDVADIQGGTTAEGIHLAA
MMAR_2257|M.marinum_M               GSTLSAAVHGWVLARA-NRDRALEFFQQVLESDVADIQGGTTAEGVHLAA
Mvan_4107|M.vanbaalenii_PYR-1       GSTLSGVVHTWVLARA-NRNRALEFFQQALKSDVSDIQGGTTSEGIHLAA
Mb2029|M.bovis_AF2122/97            GSTLSAVVHAWVLARA-NRSNAMEYFRQVLRSDIADVQGGTTQEGIHLAA
Rv2006|M.tuberculosis_H37Rv         GSTLSAVVHAWVLARA-NRSNAMEYFRQVLRSDIADVQGGTTQEGIHLAA
MSMEG_3954|M.smegmatis_MC2_155      GSTLSAVVHSWVLARG-HREQAMEFFVQALNSDVADIQGGTTAEGIHLAA
Mflv_4989|M.gilvum_PYR-GCK          GSTLSAVVHSWVLARG-DRREAMHYFRRVLASDVVDIQRGTTAEGIHLAA
MLBr_00392|M.leprae_Br4923          DSSLSACTQAVMCAEVGHLELAHDYAYEAALIDLRDLHR-NTRDGLHMAS
MUL_0906|M.ulcerans_Agy99           DSSLSACTQAVMCADVGHLELAHDYAYEAALIDLRDLHR-NTRDGLHMAS
MAV_4352|M.avium_104                DSSLSACTQAVMCAEVGHLELAHDYAYEAALIDLRDLHH-NTRDGLHMAS
                                    .*:**. .:  : *   .   * .:  ..   *: *::  .* :*:*:*:

TH_1155|M.thermoresistible__bu      MAGSVDLVQRCFTGLETRSDRIVLSPNWPESLGALGFPIRYRGHQMYVRV
MMAR_2257|M.marinum_M               MAGSVDFVQRCFTGLEIRADRIVLSPHWPEYLGALGFPIHYRGNHLHLRV
Mvan_4107|M.vanbaalenii_PYR-1       MAGTVDLMQRCFTGLETRSNRIILSPYWPESLGVLAIPIHYRGLHLHLRV
Mb2029|M.bovis_AF2122/97            MAGSIDLPQRCYSGLELRDDRLVLSPQWPEALGPLEFPFVYRRHQLSLRI
Rv2006|M.tuberculosis_H37Rv         MAGSIDLLQRCYSGLELRDDRLVLSPQWPEALGPLEFPFVYRRHQLSLRI
MSMEG_3954|M.smegmatis_MC2_155      MAGSVDLLQRCFTGLETRGDRLVLGPCWPEALGVLSFRMYYRGHNLHLRV
Mflv_4989|M.gilvum_PYR-GCK          MAGSIDLLQRCFTGLELRRDRIVVGPMWPEPLGRLAFTFRYRGHRLRLTV
MLBr_00392|M.leprae_Br4923          LAGAWTALVGGFGGLRDDEGILSIDPQLPHGISRLRFRLRWRGFRLTVDA
MUL_0906|M.ulcerans_Agy99           LAGAWTALVGGFGGLRDDEGILSIDPQLPDGISRLRFRLRWRGYRLTVDA
MAV_4352|M.avium_104                LAGAWTALVSGFGGLRDDEGVLSLDPQLPDGISRLRFRLRWRDFRVTVDV
                                    :**:       : **.   . : :.*  *. :. * : : :*  .: :  

TH_1155|M.thermoresistible__bu      SGRGAEISVAPRDLPPVAVECNGRVQRLEPGTTVRFT-------------
MMAR_2257|M.marinum_M               SGKGAEISVEPRDVPPVEVECHGRVERLLPGSTVRFS-------------
Mvan_4107|M.vanbaalenii_PYR-1       SGKGVIISVDPRDAAGIEVECRGQVVQLMPGTTVRFPG------------
Mb2029|M.bovis_AF2122/97            SGRSATLTAESGDAEPIEVECRGHVQRLRCGHTIEVGCSR----------
Rv2006|M.tuberculosis_H37Rv         SGRSATLTAESGDAEPIEVECRGHVQRLRCGHTIEVGCSR----------
MSMEG_3954|M.smegmatis_MC2_155      SGRTASVISAIGSAAPITLECRGRTWQLCAGTTIDVG-------------
Mflv_4989|M.gilvum_PYR-GCK          LGRSSTLSAEPSEASPILVECRGQAQTLVAGGTVEFTR------------
MLBr_00392|M.leprae_Br4923          RHADVTYTLRDGPGGELTIRHAGEHLTLKSDSPSTIAVRDRKPLLPPPSQ
MUL_0906|M.ulcerans_Agy99           NHSTVTFTLRDGPGAELTIRHAGKDLELSSTKPTTISVHKHKPLLPPPPQ
MAV_4352|M.avium_104                NHADVTYTLRDGPGGELTIQHAGAELELSTQSPTTVAVRPRKPLLPPPQQ
                                                    : :.  *    *    .  .              

TH_1155|M.thermoresistible__bu      ----------------------
MMAR_2257|M.marinum_M               ----------------------
Mvan_4107|M.vanbaalenii_PYR-1       ----------------------
Mb2029|M.bovis_AF2122/97            ----------------------
Rv2006|M.tuberculosis_H37Rv         ----------------------
MSMEG_3954|M.smegmatis_MC2_155      ----------------------
Mflv_4989|M.gilvum_PYR-GCK          ----------------------
MLBr_00392|M.leprae_Br4923          PPGREPVSRRHKSLIISAAR--
MUL_0906|M.ulcerans_Agy99           PPGREPVHRRNMAAKVWASTAT
MAV_4352|M.avium_104                PPGREPTHRRAVSRSSPGQ---