For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_1094 ()

annotation: PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN
coordinates: 2148252 - 2148695
length: 148

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1094-100% (148)PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1495-6e-4062.04% (137) transcriptional regulatory protein
M. gilvum PYR-GCKMflv_3678-7e-3969.16% (107) putative transcriptional regulator
M. tuberculosis H37RvRv1460-2e-4062.77% (137) transcriptional regulatory protein
M. leprae Br4923MLBr_00592-5e-3972.38% (105) putative DNA-binding protein
M. abscessus ATCC 19977MAB_2750c-3e-3462.28% (114) transcriptional regulatory protein
M. marinum MMMAR_2265-1e-4165.69% (137) transcriptional regulatory protein
M. avium 104MAV_3319-1e-4365.44% (136) DNA-binding protein
M. smegmatis MC2 155MSMEG_3121-7e-4667.86% (140) DNA-binding protein
M. ulcerans Agy99MUL_1861-9e-4265.69% (137) transcriptional regulatory protein
M. vanbaalenii PYR-1Mvan_2732-6e-3972.38% (105) putative transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb1495|M.bovis_AF2122/97            MTSTTLPHRASLVDRSTEFCHTDVVKIP-------------AVSTTV--P
Rv1460|M.tuberculosis_H37Rv         MTSTTLPHRASLVDRSTEFCHTDVVKIP-------------AVSTTV--P
MAV_3319|M.avium_104                --------------------------MG-------------AAG------
MMAR_2265|M.marinum_M               -----------MLDRCPELRHTGVVKIQPEFS---------AAHSAA--L
MUL_1861|M.ulcerans_Agy99           -----------MLDRCPELRHTGVVKIQPEFS---------AAHSAA--L
MLBr_00592|M.leprae_Br4923          --MLNVHRGYPSLDRSPELRHTGVVKIRSELD---------AATT-----
Mflv_3678|M.gilvum_PYR-GCK          ------------------MRHTGVVKFRSQSS---------EAPTSAPLH
Mvan_2732|M.vanbaalenii_PYR-1       ------------------------------------------------MS
MAB_2750c|M.abscessus_ATCC_199      ------------------MKFGPGTSAGTAAT---------AAPSLNAAP
MSMEG_3121|M.smegmatis_MC2_155      ------------MEPSDEFRHNGVVKLRGGATSPVATGPSVPAADEVPGV
TH_1094|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1495|M.bovis_AF2122/97            AAVSDGH--TRRAIVRLLLESGSITAGEIGDRLGLSAAGVRRHLDALIEA
Rv1460|M.tuberculosis_H37Rv         AAVSDGH--TRRAIVRLLLESGSITAGEIGDRLGLSAAGVRRHLDALIEA
MAV_3319|M.avium_104                AAVPDGH--TRRAIVRLLLESGSITAGEIGDRLGLAAAGVRRHLDALIEA
MMAR_2265|M.marinum_M               VAGSDGH--TRRAIVRLLLESGSITAGEIGDRLGLSAAGVRRHLDALIDA
MUL_1861|M.ulcerans_Agy99           VAGSDGH--TRRAIVRLLLESGSITAGEIGDRLGLSAAGVRRHLDALIDA
MLBr_00592|M.leprae_Br4923          VAVSDGH--TRRAVVRLLLESGSITAGEISDRLGLSAAGVRRHLDVLIEM
Mflv_3678|M.gilvum_PYR-GCK          PVDGDHHGDTRSAIVRLLLESGPVTAGHIGQQLGLSAAGVRRHLDALIEA
Mvan_2732|M.vanbaalenii_PYR-1       PQAADGH--TRGAIVRLLLESGPVTASRIGERLGLSAAGVRRHLDALIEA
MAB_2750c|M.abscessus_ATCC_199      AASTEGQ--TRAAVVRLLLESGPITAGEIGERLGLSAAGVRRHLDALIDA
MSMEG_3121|M.smegmatis_MC2_155      ISTADGQ--TRRAIIKLLLE-GPITAGQIGERLGISAAGVRRHLDALIEA
TH_1094|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1495|M.bovis_AF2122/97            GDAEASAAAPWQQVGRGRPAKRYRLTAAGRAKLDHSYDDLASAAMRQLRE
Rv1460|M.tuberculosis_H37Rv         GDAEASAAAPWQQVGRGRPAKRYRLTAAGRAKLDHSYDDLASAAMRQLRE
MAV_3319|M.avium_104                GDAESIAPAAWQHAGRGRPAKRYRLTSAGRAKLDHAYDDLAAAAMRQLRE
MMAR_2265|M.marinum_M               GDAESAPAAPWQQAGRGRPAKRYRLTPGGRAKLEHSYDDLAAAAMRQLRE
MUL_1861|M.ulcerans_Agy99           GDAESAPAAPWQQVGRGRPAKRYRLTPGGRAKLEHSYDDLAAAAMRQLRE
MLBr_00592|M.leprae_Br4923          GDAESATAAPWQQVGRGRPAKHYRLTAVGRAKLGHAYDTLASAAMRQLRE
Mflv_3678|M.gilvum_PYR-GCK          GDAQANAAAAWQQEGRGRPAKRYRLTAAGRAKLEHTYDDLASAAMRQLRE
Mvan_2732|M.vanbaalenii_PYR-1       GEAQANAAAAWQQEGRGRPAKRYQLTSAGRAKLEHTYDDLASAAMRQLRE
MAB_2750c|M.abscessus_ATCC_199      GDAVAHPAAAWQHHGRGRPAKRFQLTADGRAKLNHAYDDLASAAMRQLRE
MSMEG_3121|M.smegmatis_MC2_155      GDAQASAAAAWQHTGRGRPAKRYRLTAAGRAKLGHSYDDLAVAAIRQLRE
TH_1094|M.thermoresistible__bu      -----------------VPSDTX----XGRS-------------------
                                                      *:.       **:                   

Mb1495|M.bovis_AF2122/97            IGGEEAVRTFARRRIDAILADVAPADGP-DDAALEAAAERIATALSKAGY
Rv1460|M.tuberculosis_H37Rv         IGGEEAVRTFARRRIDAILADVAPADGP-DDAALEAAAERIATALSKAGY
MAV_3319|M.avium_104                IGGEEAVQAFARQRIDAILAGVPGAASA-ADDDIEAAAQRIATALTKAGY
MMAR_2265|M.marinum_M               IGGDDAVRTFARRRIDAILAGVPAAASP-DDAAVEAAAERVASALTKAGY
MUL_1861|M.ulcerans_Agy99           IGGDDAVRTFARRRIDAILAGVPAAASP-DDAAVEAAAERVASALTKAGY
MLBr_00592|M.leprae_Br4923          IGGEDAVRTFARQRIDAILADVEPAGG---GADVEAAANRVASALSDAGY
Mflv_3678|M.gilvum_PYR-GCK          IGGDDAVRTFARRRIDTILAGVEPVDDASRGEEIEAAADRIADALTGAGY
Mvan_2732|M.vanbaalenii_PYR-1       IGGEEAVRTFARRRIDTILSGVEHVD---GGEGVEAAAGQIAEALSAAGF
MAB_2750c|M.abscessus_ATCC_199      IGGDEAVRTFARRRIDTILGDLTIGAPQ---DDLPAAVGQVADALTRAGY
MSMEG_3121|M.smegmatis_MC2_155      IGGKDAVRTFARRRIDTILSGVTAGSG-----DVAQTAERVADAMTKAGY
TH_1094|M.thermoresistible__bu      ----------PRRRIDAILAGVLGVSEG--AGDVESTAERVARALTRAGY
                                              .*:***:**..:           :  :. ::* *:: **:

Mb1495|M.bovis_AF2122/97            VATTTRVGGP---IHGVQICQHHCPVSHVAEEFPELCETEQQAMAEVLGT
Rv1460|M.tuberculosis_H37Rv         VATTTRVGGP---IHGVQICQHHCPVSHVAEEFPELCETEQQAMAEVLGT
MAV_3319|M.avium_104                VATTTQVGGP---IHGVQICQHHCPVSHVAEEFPELCDAEQQAMAEVLGT
MMAR_2265|M.marinum_M               VATTTRVGGP---IHGVQICQHHCPVSHVAEEFPELCEAEQQAIAEVLGT
MUL_1861|M.ulcerans_Agy99           VATTTRVGGP---IHGVQICQHHCPVSHVAEEFPELCEAEQQAIAEVLGT
MLBr_00592|M.leprae_Br4923          VATTARVGGP---IHGVEICQHHCPVSHVAEEFPELCETEQQAIAEVLGT
Mflv_3678|M.gilvum_PYR-GCK          ATTTPRVRGP---LSGVQICQHHCPVSHVAEQFPELCEAEQQAMSDVLGT
Mvan_2732|M.vanbaalenii_PYR-1       ATTTARVGGP---VGGVQICQHHCPVSHVAEEFPELCEAEQQAMAEVLGT
MAB_2750c|M.abscessus_ATCC_199      AASTQKVGGSGGFLQGVQICQHHCPVSHVAAEFPELCEAEQQAFAAVLGT
MSMEG_3121|M.smegmatis_MC2_155      ATTTAPVSGP---IRGVQICQHHCPVSHVAEEFPELCETEREAFAEILGT
TH_1094|M.thermoresistible__bu      AATTSRVPGP---VDGVQICQHHCPVSHVAEEFPELCDAEREAFAEILDT
                                    .::*  * *.   : **:************ :*****::*::*:: :*.*

Mb1495|M.bovis_AF2122/97            HVQRLATIVNGDCACTTHVPLSP---------------APSPRPPATSTE
Rv1460|M.tuberculosis_H37Rv         HVQRLATIVNGDCACTTHVPLSP---------------APSPRPPATSTE
MAV_3319|M.avium_104                HVQRLATIVNGDCACTTHVPLAQTA------------KAPSPRRHTTSNK
MMAR_2265|M.marinum_M               HVQRLATIVNGDCACTTHVPLTP---------------APSPRQHLTSTG
MUL_1861|M.ulcerans_Agy99           HVQRLATIVNGDCACTTHVPLTP---------------APSPRQHLTSTG
MLBr_00592|M.leprae_Br4923          HVQRLAMIVNGDCACTTHVPLMS---------------VPSKT-------
Mflv_3678|M.gilvum_PYR-GCK          HVQRLATIVNGDCACTTHVPLVP------------------ER-------
Mvan_2732|M.vanbaalenii_PYR-1       HVQRLATIANGDFACTTHVPLSP------------------AGR------
MAB_2750c|M.abscessus_ATCC_199      HVQRLATIANGDCACTTHVPMQT-----------------SPPA------
MSMEG_3121|M.smegmatis_MC2_155      HVQRLATIVNGDCACTTHVPLDLDPPGEHTDHPKDVRSTARDRTTTPSDQ
TH_1094|M.thermoresistible__bu      HVQRLATIVNGDNACTTHVPLPNRMPSHRKQPRKP--NRVQPRTATTSPQ
                                    ****** *.*** *******:                             

Mb1495|M.bovis_AF2122/97            GVSR
Rv1460|M.tuberculosis_H37Rv         GASR
MAV_3319|M.avium_104                GASL
MMAR_2265|M.marinum_M               GASA
MUL_1861|M.ulcerans_Agy99           GASA
MLBr_00592|M.leprae_Br4923          ----
Mflv_3678|M.gilvum_PYR-GCK          ----
Mvan_2732|M.vanbaalenii_PYR-1       ----
MAB_2750c|M.abscessus_ATCC_199      ----
MSMEG_3121|M.smegmatis_MC2_155      GAST
TH_1094|M.thermoresistible__bu      GASS