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M. ulcerans Agy99 MUL_1861 (-)

annotation: transcriptional regulatory protein
coordinates: 2062649 - 2063434
length: 261

LLDRCPELRHTGVVKIQPEFSAAHSAALVAGSDGHTRRAIVRLLLESGSITAGEIGDRLGLSAAGVRRHL
DALIDAGDAESAPAAPWQQVGRGRPAKRYRLTPGGRAKLEHSYDDLAAAAMRQLREIGGDDAVRTFARRR
IDAILAGVPAAASPDDAAVEAAAERVASALTKAGYVATTTRVGGPIHGVQICQHHCPVSHVAEEFPELCE
AEQQAIAEVLGTHVQRLATIVNGDCACTTHVPLTPAPSPRQHLTSTGGASA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_1861--100% (261)transcriptional regulatory protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1495-1e-11883.08% (260) transcriptional regulatory protein
M. gilvum PYR-GCKMflv_3678-3e-9774.07% (243) putative transcriptional regulator
M. tuberculosis H37RvRv1460-1e-11983.46% (260) transcriptional regulatory protein
M. leprae Br4923MLBr_00592-1e-10981.38% (247) putative DNA-binding protein
M. abscessus ATCC 19977MAB_2750c-2e-8973.01% (226) transcriptional regulatory protein
M. marinum MMMAR_2265-1e-14899.62% (261) transcriptional regulatory protein
M. avium 104MAV_3319-1e-10982.35% (238) DNA-binding protein
M. smegmatis MC2 155MSMEG_3121-2e-9268.09% (257) DNA-binding protein
M. thermoresistible (build 8)TH_1094-2e-4165.69% (137) PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN
M. vanbaalenii PYR-1Mvan_2732-1e-9176.74% (215) putative transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3678|M.gilvum_PYR-GCK          ------------------MRHTGVVKFRSQSS---------EAPTSAPLH
Mvan_2732|M.vanbaalenii_PYR-1       ------------------------------------------------MS
MUL_1861|M.ulcerans_Agy99           -----------MLDRCPELRHTGVVKIQPEFS---------AAHSAA--L
MMAR_2265|M.marinum_M               -----------MLDRCPELRHTGVVKIQPEFS---------AAHSAA--L
MLBr_00592|M.leprae_Br4923          --MLNVHRGYPSLDRSPELRHTGVVKIRSELD---------AATT-----
Mb1495|M.bovis_AF2122/97            MTSTTLPHRASLVDRSTEFCHTDVVKIP-------------AVSTTV--P
Rv1460|M.tuberculosis_H37Rv         MTSTTLPHRASLVDRSTEFCHTDVVKIP-------------AVSTTV--P
MAV_3319|M.avium_104                --------------------------MG-------------AAG------
MAB_2750c|M.abscessus_ATCC_199      ------------------MKFGPGTSAGTAAT---------AAPSLNAAP
MSMEG_3121|M.smegmatis_MC2_155      ------------MEPSDEFRHNGVVKLRGGATSPVATGPSVPAADEVPGV
TH_1094|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3678|M.gilvum_PYR-GCK          PVDGDHHGDTRSAIVRLLLESGPVTAGHIGQQLGLSAAGVRRHLDALIEA
Mvan_2732|M.vanbaalenii_PYR-1       PQAADGH--TRGAIVRLLLESGPVTASRIGERLGLSAAGVRRHLDALIEA
MUL_1861|M.ulcerans_Agy99           VAGSDGH--TRRAIVRLLLESGSITAGEIGDRLGLSAAGVRRHLDALIDA
MMAR_2265|M.marinum_M               VAGSDGH--TRRAIVRLLLESGSITAGEIGDRLGLSAAGVRRHLDALIDA
MLBr_00592|M.leprae_Br4923          VAVSDGH--TRRAVVRLLLESGSITAGEISDRLGLSAAGVRRHLDVLIEM
Mb1495|M.bovis_AF2122/97            AAVSDGH--TRRAIVRLLLESGSITAGEIGDRLGLSAAGVRRHLDALIEA
Rv1460|M.tuberculosis_H37Rv         AAVSDGH--TRRAIVRLLLESGSITAGEIGDRLGLSAAGVRRHLDALIEA
MAV_3319|M.avium_104                AAVPDGH--TRRAIVRLLLESGSITAGEIGDRLGLAAAGVRRHLDALIEA
MAB_2750c|M.abscessus_ATCC_199      AASTEGQ--TRAAVVRLLLESGPITAGEIGERLGLSAAGVRRHLDALIDA
MSMEG_3121|M.smegmatis_MC2_155      ISTADGQ--TRRAIIKLLLE-GPITAGQIGERLGISAAGVRRHLDALIEA
TH_1094|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3678|M.gilvum_PYR-GCK          GDAQANAAAAWQQEGRGRPAKRYRLTAAGRAKLEHTYDDLASAAMRQLRE
Mvan_2732|M.vanbaalenii_PYR-1       GEAQANAAAAWQQEGRGRPAKRYQLTSAGRAKLEHTYDDLASAAMRQLRE
MUL_1861|M.ulcerans_Agy99           GDAESAPAAPWQQVGRGRPAKRYRLTPGGRAKLEHSYDDLAAAAMRQLRE
MMAR_2265|M.marinum_M               GDAESAPAAPWQQAGRGRPAKRYRLTPGGRAKLEHSYDDLAAAAMRQLRE
MLBr_00592|M.leprae_Br4923          GDAESATAAPWQQVGRGRPAKHYRLTAVGRAKLGHAYDTLASAAMRQLRE
Mb1495|M.bovis_AF2122/97            GDAEASAAAPWQQVGRGRPAKRYRLTAAGRAKLDHSYDDLASAAMRQLRE
Rv1460|M.tuberculosis_H37Rv         GDAEASAAAPWQQVGRGRPAKRYRLTAAGRAKLDHSYDDLASAAMRQLRE
MAV_3319|M.avium_104                GDAESIAPAAWQHAGRGRPAKRYRLTSAGRAKLDHAYDDLAAAAMRQLRE
MAB_2750c|M.abscessus_ATCC_199      GDAVAHPAAAWQHHGRGRPAKRFQLTADGRAKLNHAYDDLASAAMRQLRE
MSMEG_3121|M.smegmatis_MC2_155      GDAQASAAAAWQHTGRGRPAKRYRLTAAGRAKLGHSYDDLAVAAIRQLRE
TH_1094|M.thermoresistible__bu      -----------------VPSDTX----XGRS-------------------
                                                      *:.       **:                   

Mflv_3678|M.gilvum_PYR-GCK          IGGDDAVRTFARRRIDTILAGVEPVDDASRGEEIEAAADRIADALTGAGY
Mvan_2732|M.vanbaalenii_PYR-1       IGGEEAVRTFARRRIDTILSGVEHVD---GGEGVEAAAGQIAEALSAAGF
MUL_1861|M.ulcerans_Agy99           IGGDDAVRTFARRRIDAILAGVPAAASP-DDAAVEAAAERVASALTKAGY
MMAR_2265|M.marinum_M               IGGDDAVRTFARRRIDAILAGVPAAASP-DDAAVEAAAERVASALTKAGY
MLBr_00592|M.leprae_Br4923          IGGEDAVRTFARQRIDAILADVEPAGG---GADVEAAANRVASALSDAGY
Mb1495|M.bovis_AF2122/97            IGGEEAVRTFARRRIDAILADVAPADGP-DDAALEAAAERIATALSKAGY
Rv1460|M.tuberculosis_H37Rv         IGGEEAVRTFARRRIDAILADVAPADGP-DDAALEAAAERIATALSKAGY
MAV_3319|M.avium_104                IGGEEAVQAFARQRIDAILAGVPGAASA-ADDDIEAAAQRIATALTKAGY
MAB_2750c|M.abscessus_ATCC_199      IGGDEAVRTFARRRIDTILGDLTIGAPQ---DDLPAAVGQVADALTRAGY
MSMEG_3121|M.smegmatis_MC2_155      IGGKDAVRTFARRRIDTILSGVTAGSG-----DVAQTAERVADAMTKAGY
TH_1094|M.thermoresistible__bu      ----------PRRRIDAILAGVLGVSEG--AGDVESTAERVARALTRAGY
                                              .*:***:**..:           :  :. ::* *:: **:

Mflv_3678|M.gilvum_PYR-GCK          ATTTPRVRGP---LSGVQICQHHCPVSHVAEQFPELCEAEQQAMSDVLGT
Mvan_2732|M.vanbaalenii_PYR-1       ATTTARVGGP---VGGVQICQHHCPVSHVAEEFPELCEAEQQAMAEVLGT
MUL_1861|M.ulcerans_Agy99           VATTTRVGGP---IHGVQICQHHCPVSHVAEEFPELCEAEQQAIAEVLGT
MMAR_2265|M.marinum_M               VATTTRVGGP---IHGVQICQHHCPVSHVAEEFPELCEAEQQAIAEVLGT
MLBr_00592|M.leprae_Br4923          VATTARVGGP---IHGVEICQHHCPVSHVAEEFPELCETEQQAIAEVLGT
Mb1495|M.bovis_AF2122/97            VATTTRVGGP---IHGVQICQHHCPVSHVAEEFPELCETEQQAMAEVLGT
Rv1460|M.tuberculosis_H37Rv         VATTTRVGGP---IHGVQICQHHCPVSHVAEEFPELCETEQQAMAEVLGT
MAV_3319|M.avium_104                VATTTQVGGP---IHGVQICQHHCPVSHVAEEFPELCDAEQQAMAEVLGT
MAB_2750c|M.abscessus_ATCC_199      AASTQKVGGSGGFLQGVQICQHHCPVSHVAAEFPELCEAEQQAFAAVLGT
MSMEG_3121|M.smegmatis_MC2_155      ATTTAPVSGP---IRGVQICQHHCPVSHVAEEFPELCETEREAFAEILGT
TH_1094|M.thermoresistible__bu      AATTSRVPGP---VDGVQICQHHCPVSHVAEEFPELCDAEREAFAEILDT
                                    .::*  * *.   : **:************ :*****::*::*:: :*.*

Mflv_3678|M.gilvum_PYR-GCK          HVQRLATIVNGDCACTTHVPLVP------------------ER-------
Mvan_2732|M.vanbaalenii_PYR-1       HVQRLATIANGDFACTTHVPLSP------------------AGR------
MUL_1861|M.ulcerans_Agy99           HVQRLATIVNGDCACTTHVPLTP---------------APSPRQHLTSTG
MMAR_2265|M.marinum_M               HVQRLATIVNGDCACTTHVPLTP---------------APSPRQHLTSTG
MLBr_00592|M.leprae_Br4923          HVQRLAMIVNGDCACTTHVPLMS---------------VPSKT-------
Mb1495|M.bovis_AF2122/97            HVQRLATIVNGDCACTTHVPLSP---------------APSPRPPATSTE
Rv1460|M.tuberculosis_H37Rv         HVQRLATIVNGDCACTTHVPLSP---------------APSPRPPATSTE
MAV_3319|M.avium_104                HVQRLATIVNGDCACTTHVPLAQTA------------KAPSPRRHTTSNK
MAB_2750c|M.abscessus_ATCC_199      HVQRLATIANGDCACTTHVPMQT-----------------SPPA------
MSMEG_3121|M.smegmatis_MC2_155      HVQRLATIVNGDCACTTHVPLDLDPPGEHTDHPKDVRSTARDRTTTPSDQ
TH_1094|M.thermoresistible__bu      HVQRLATIVNGDNACTTHVPLPNRMPSHRKQPRKP--NRVQPRTATTSPQ
                                    ****** *.*** *******:                             

Mflv_3678|M.gilvum_PYR-GCK          ----
Mvan_2732|M.vanbaalenii_PYR-1       ----
MUL_1861|M.ulcerans_Agy99           GASA
MMAR_2265|M.marinum_M               GASA
MLBr_00592|M.leprae_Br4923          ----
Mb1495|M.bovis_AF2122/97            GVSR
Rv1460|M.tuberculosis_H37Rv         GASR
MAV_3319|M.avium_104                GASL
MAB_2750c|M.abscessus_ATCC_199      ----
MSMEG_3121|M.smegmatis_MC2_155      GAST
TH_1094|M.thermoresistible__bu      GASS