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M. thermoresistible (build 8) TH_1007 (ribG)

annotation: PROBABLE BIFUNCTIONAL riboflavin biosynthesis protein RIBG : Diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino) uracil reductase (HTP reductase)
coordinates: 2002617 - 2003243
length: 209

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_1007 ribG - 100% (209) PROBABLE BIFUNCTIONAL riboflavin biosynthesis protein RIBG : Diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino) uracil reductase (HTP reductase)
M. thermoresistible (build 8) TH_1514 ribD 2e-06 45.45% (66) POSSIBLE BIFUNCTIONAL ENZYME RIBOFLAVIN BIOSYNTHESIS PROTEIN
M. thermoresistible (build 8) TH_2924 - 7e-05 47.92% (48) PUTATIVE bifunctional deaminase-reductase domain protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb1444 ribG 8e-91 76.92% (208) bifunctional diaminohydroxyphosphoribosylaminopyrimidine
M. gilvum PYR-GCK Mflv_3727 - 6e-99 83.09% (207) riboflavin biosynthesis protein RibD
M. tuberculosis H37Rv Rv1409 ribG 8e-91 76.92% (208) bifunctional diaminohydroxyphosphoribosylaminopyrimidine
M. leprae Br4923 MLBr_00555 ribG 1e-89 75.48% (208) putative bifunctional riboflavin-specific
M. abscessus ATCC 19977 MAB_2808c - 2e-89 75.73% (206) bifunctional riboflavin biosynthesis protein RibG
M. marinum M MMAR_2218 ribG 3e-91 77.40% (208) bifunctional riboflavin biosynthesis protein RibG
M. avium 104 MAV_3368 ribD 9e-94 78.85% (208) riboflavin biosynthesis protein RibD
M. smegmatis MC2 155 MSMEG_3067 ribD 8e-98 81.16% (207) riboflavin biosynthesis protein RibD
M. ulcerans Agy99 MUL_1805 ribG 2e-91 77.40% (208) bifunctional riboflavin biosynthesis protein RibG
M. vanbaalenii PYR-1 Mvan_2690 - 4e-97 81.16% (207) riboflavin biosynthesis protein RibD

CLUSTAL 2.0.9 multiple sequence alignment


MAB_2808c|M.abscessus_ATCC_199      --MTNPIGLDEAMDLAIRAAEEVKGSTYPNPPVGAVILDAAGQVAGVGGT
MSMEG_3067|M.smegmatis_MC2_155      --MS--ISVEAAMRLAIDQAEQVKGATYPNPPVGAVILDRDGQVAGVGGT
Mflv_3727|M.gilvum_PYR-GCK          ------MNLDAAMAAAIVQSERVKGRTYPNPPVGAVILDSDGEIAGVGAT
Mvan_2690|M.vanbaalenii_PYR-1       ------MKLDAAMAAAIEQSERVKGRTYPNPPVGAVILDRDGEIAGVGAT
TH_1007|M.thermoresistible__bu      --------------------------------------------------
Mb1444|M.bovis_AF2122/97            MNVEQVKSIDEAMGLAIEHSYQVKGTTYPNPPVGAVIVDPNGRIVGAGGT
Rv1409|M.tuberculosis_H37Rv         MNVEQVKSIDEAMGLAIEHSYQVKGTTYPKPPVGAVIVDPNGRIVGAGGT
MMAR_2218|M.marinum_M               MTVEQVKSLEEAMRLAIEQSMLVKGTTYPNPPVGAVIVDQEGRVVGIGGT
MUL_1805|M.ulcerans_Agy99           MTVEQVKSLEEAMRLAIEQSMLVKGTTYPNPPVGAVIVDQEGWVVGIGGT
MLBr_00555|M.leprae_Br4923          MNVQTVDSLDAAMRLAVEQSYLVKGATYPNPPVGAVIVDPDGRVVGVGAT
MAV_3368|M.avium_104                MTASLGDRLDAAMRLAIEQSNQVKGNTYPNPPVGAVVLDGRGEVVGVGGT
                                                                                      

MAB_2808c|M.abscessus_ATCC_199      RPPGQEHAEVVALAGAGAAARGGTAVVTLEPCNHQGRTGPCVDALAAAGV
MSMEG_3067|M.smegmatis_MC2_155      QPTGGPHAEVMALRAAAERAEGGTAVVTLEPCNHHGRTPPCVDGLVAAGI
Mflv_3727|M.gilvum_PYR-GCK          APTGGPHAEVVALRRAGERAAGGTAVVTLEPCNHFGRTPPCVDALIDAGV
Mvan_2690|M.vanbaalenii_PYR-1       APPGGPHAEVVALRRAGERAVGGTAVVTLEPCNHFGRTPPCVDALLDAGI
TH_1007|M.thermoresistible__bu      --------------------------------------------------
Mb1444|M.bovis_AF2122/97            EPAGGDHAEVVALRRAGGLATGAIVVVTMEPCNHYGKTPPCVNALIEARV
Rv1409|M.tuberculosis_H37Rv         EPAGGDHAEVVALRRAGGLAAGAIVVVTMEPCNHYGKTPPCVNALIEARV
MMAR_2218|M.marinum_M               QPSGGDHAEVVALRKAGGLAAGAIAVVTMEPCNHFGKTPPCVNALIEARV
MUL_1805|M.ulcerans_Agy99           QPSGGDHAEVVALRKAGGLAAGAIAVVTMEPCNHFGKTPPCVNALIEARV
MLBr_00555|M.leprae_Br4923          EPAGGDHAEVVALRSAGVTAAGAIAVVTLEPCNHYGKTPPCVNALLEAKV
MAV_3368|M.avium_104                EPAGGDHAEILALRRAGDLAAGGTVVVTLEPCNHHGKTPPCVDALLEAGV
                                                                                      

MAB_2808c|M.abscessus_ATCC_199      SRVVYAVADPNPQAAGGAARLRTLGIEVLDGLASDRVSAGPLREWLHKQR
MSMEG_3067|M.smegmatis_MC2_155      SRVVYAVADPNPVAAGGSARMASSGIEVTSGVLSDEVAGGPLREWLHKQR
Mflv_3727|M.gilvum_PYR-GCK          AAVAFAVADPNPAAAGGAARLAAAGVRVSAGVVADAVTGGPLREWLHKQR
Mvan_2690|M.vanbaalenii_PYR-1       AEVAFAVADPDPVAAGGAARLAESGVRVSAGVLAADVTGGPLREWLHKQR
TH_1007|M.thermoresistible__bu      -------------------------------VLADEVAAGPLREWLHKTR
Mb1444|M.bovis_AF2122/97            GTVVYAVADPNGIAGGGAGRLSAAGLQVRSGVLAEQVAAGPLREWLHKQR
Rv1409|M.tuberculosis_H37Rv         GTVVYAVADPNGIAGGGAGRLSAAGLQVRSGVLAEQVAAGPLREWLHKQR
MMAR_2218|M.marinum_M               GTVIYGVADPNGIAGGGAGRLSAAGLQVRSGVLADHVAAGPLREWLHKQR
MUL_1805|M.ulcerans_Agy99           GTVIYGVADPNGIAGGGAGRLSAAGLQVRSGVLADHVAAGPLREWLHKQR
MLBr_00555|M.leprae_Br4923          DKVAYAIADPNASAGGGAARLTAAGVHVQSGVLADLVTAGPLREWLHKQR
MAV_3368|M.avium_104                STVVYAVADPNPQAAGGAGRLQEAGVTVRSGLLADEVSGGPLREWLHKQR
                                                                   : :  *:.********* *

MAB_2808c|M.abscessus_ATCC_199      TGRPHVTWKYGASVDGRSAANDGTSQWITSEQSRADVHRRRAFADAVLVG
MSMEG_3067|M.smegmatis_MC2_155      TGLPHVTWKFATSVDGRSAAADGSSQWITSAAARADVHRRRAAADAIVVG
Mflv_3727|M.gilvum_PYR-GCK          TGKPHVTWKFAASVDGRSAAADGTSQWITSEASRADVHRRRAAADAIVAG
Mvan_2690|M.vanbaalenii_PYR-1       TGMPHVTWKFATSVDGRSAAADGSSQWITSEAARADVHRRRATADAIIVG
TH_1007|M.thermoresistible__bu      TGRPHVTWKFAASVDGRSAAADGTSQWITSEEARADVHRRRAAADAIVVG
Mb1444|M.bovis_AF2122/97            TGLPHVTWKYATSIDGRSAAADGSSQWISSEAARLDLHRRRAIADAILVG
Rv1409|M.tuberculosis_H37Rv         TGLPHVTWKYATSIDGRSAAADGSSQWISSEAARLDLHRRRAIADAILVG
MMAR_2218|M.marinum_M               TGLPHVTWKYATSIDGRSAAADGSSQWISSEAARADLHRRRAISDAIVVG
MUL_1805|M.ulcerans_Agy99           TGLPHVTWKYATSIDGRSAAADGSSQWISSEAARADLHRRRAISDAIVVG
MLBr_00555|M.leprae_Br4923          TGLPHVTWKYASSIDGRSAAADGSSRWLSSEASRADLHRRRATADAIVVG
MAV_3368|M.avium_104                TGLPHLTWKYASSVDGRSAAADGSSRWISSEASRLDLHRRRAAADAIVVG
                                    ** **:***:.:*:****** **:*:*::*  :* *:***** :**::.*

MAB_2808c|M.abscessus_ATCC_199      TGTVFADDPQLTARTPDNELVPHQPLRVVVGMREVSSDAKVLNDDSHTMV
MSMEG_3067|M.smegmatis_MC2_155      TGTVFVDDPSLTARLPDGTLADRQPLRVVVGRREVSSDANVLNDDSRTMV
Mflv_3727|M.gilvum_PYR-GCK          TGTVFADDPALTARLPDGSLADHQPLRVVVGMREISPDATVLNDDSRTMV
Mvan_2690|M.vanbaalenii_PYR-1       TGTVFVDDPALTARLPDGSLADHQPLRVVVGKREISPDATVLNDDSRTMV
TH_1007|M.thermoresistible__bu      TGTVLADDPTLTARRPDGSLAERQPLRVVVGTRDISADANVLNDDSRTMV
Mb1444|M.bovis_AF2122/97            TGTVLADDPALTARLADGSLAPQQPLRVVVGKRDIPPEARVLNDEARTMM
Rv1409|M.tuberculosis_H37Rv         TGTVLADDPALTARLADGSLAPQQPLRVVVGKRDIPPEARVLNDEARTMM
MMAR_2218|M.marinum_M               TGTVLVDDPTLTARLSDGSLAAEQPLRVVVGKRDIPPEAKVLNDDARTMM
MUL_1805|M.ulcerans_Agy99           TGTVLVDDPTLTARLSDGSLAAEQPLRVVVGKRDIPPEAKVLNDDARTMM
MLBr_00555|M.leprae_Br4923          TGTVLADNPTLTARLANGALADRQPLRVVVGMREIPLEANVLNDDSPTMV
MAV_3368|M.avium_104                TGTVLADDPALTARLPDGTLADRQPLRVVVGMREIPSEAKVLNDDSRTMV
                                    ****:.*:* **** .:. *. .******** *::. :* ****:: **:

MAB_2808c|M.abscessus_ATCC_199      IRTHDPAEVLAALGDRTDIILEGGPTLAGAFLRAGLVDRILAYLAPMLLG
MSMEG_3067|M.smegmatis_MC2_155      IRTHDPHEVLRALSDRTDIMLEGGPTLAGAFLRAGVVNRILAYVAPILLG
Mflv_3727|M.gilvum_PYR-GCK          IRTRDPHEVIQALTDRTDVLVEGGPTLAGAFLRAGAIDRILAYVAPILLG
Mvan_2690|M.vanbaalenii_PYR-1       IRTHNPHEVIKALADRTDVFVEGGPTLAGAFLRAGVIDRILAYVAPILLG
TH_1007|M.thermoresistible__bu      IRTHDPHEVVRALADRTDVLLEGGPTLAGAFVRAGLVDRILAYVAPVLLG
Mb1444|M.bovis_AF2122/97            IRTHEPMEVLRALSDRTDVLLEGGPTLAGAFLRAGAINRILAYVAPILLG
Rv1409|M.tuberculosis_H37Rv         IRTHEPMEVLRALSDRTDVLLEGGPTLAGAFLRAGAINRILAYVAPILLG
MMAR_2218|M.marinum_M               IKTHEPVEVLRALSDRTDVLLEGGPTLAGAFLRAGAINRILAYVAPILLG
MUL_1805|M.ulcerans_Agy99           IKTHEPVEVLRALSDRTDVLLEGGPTLAGAFLRAGAINRILAYVAPILLG
MLBr_00555|M.leprae_Br4923          IRTHDPMEVLKALADRTDVLLEGGPTLAGAFLRAGTINRILAYVAPILLG
MAV_3368|M.avium_104                IRTHDPAEVLKAVSDRTDVLLEGGPTLAGAFVRAGLVNRILVYLAPTLLG
                                    *:*::* **: *: ****:::**********:*** ::***.*:** ***

MAB_2808c|M.abscessus_ATCC_199      GNVPAVEDVGVTTLSRALRWEYDQIERMGPDVLLSLVPRLPV
MSMEG_3067|M.smegmatis_MC2_155      GPITAVDDVGVPSIAHAQRWRFDCVQTIGPDVLMSLVPN---
Mflv_3727|M.gilvum_PYR-GCK          GPVTAVDDVGVSSITQAHRWRFDGMQAIGPDVLLSLVPN---
Mvan_2690|M.vanbaalenii_PYR-1       GPITAVDDVGVLSIAQAQRWRFDGMTAVGPDVLLSLTPV---
TH_1007|M.thermoresistible__bu      GPVTVVDDVGVTTIGNAHRWRFDGMTSVGPDVLLSLVPR---
Mb1444|M.bovis_AF2122/97            GPVTAVDDVGVSNITNALRWQFDSVEKVGPDLLLSLVAR---
Rv1409|M.tuberculosis_H37Rv         GPVTAVDDVGVSNITNALRWQFDSVEKVGPDLLLSLVAR---
MMAR_2218|M.marinum_M               GPVTAVDDVGVSSIAHALRWQFDGVERCGPDLLLSLVSR---
MUL_1805|M.ulcerans_Agy99           GPVTAVDDVGVSSIAHALRWQFDGVERCGPDLLLSLVSR---
MLBr_00555|M.leprae_Br4923          GPVTAVDDVGVPNIARALRWQFDGIDRAGSDLVISLVTR---
MAV_3368|M.avium_104                GPVTAVDDVGVPTIAKALRWQFDGVDRVGPDLLLSLVPRSG-
                                    * :..*:**** .: .* **.:* :   *.*:::**..

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_1007	ribG	-	100% (209)	PROBABLE BIFUNCTIONAL riboflavin biosynthesis protein RIBG : Diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino) uracil reductase (HTP reductase)
M. thermoresistible (build 8)	TH_1514	ribD	2e-06	45.45% (66)	POSSIBLE BIFUNCTIONAL ENZYME RIBOFLAVIN BIOSYNTHESIS PROTEIN
M. thermoresistible (build 8)	TH_2924	-	7e-05	47.92% (48)	PUTATIVE bifunctional deaminase-reductase domain protein