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M. thermoresistible (build 8) TH_0961 ()

annotation: CONSERVED HYPOTHETICAL PROTEIN
coordinates: 1906179 - 1907006
length: 276

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0961-100% (276)CONSERVED HYPOTHETICAL PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3696c-2e-9066.80% (250) hypothetical protein Mb3696c
M. gilvum PYR-GCKMflv_1375-2e-9564.71% (272) NUDIX hydrolase
M. tuberculosis H37RvRv3672c-2e-9066.80% (250) hypothetical protein Rv3672c
M. leprae Br4923MLBr_02299-4e-8564.40% (250) hypothetical protein MLBr_02299
M. abscessus ATCC 19977MAB_0420-6e-6856.47% (255) hypothetical protein MAB_0420
M. marinum MMMAR_5160-2e-8763.35% (251) hypothetical protein MMAR_5160
M. avium 104MAV_0457-3e-9068.65% (252) hydrolase, nudix family protein
M. smegmatis MC2 155MSMEG_6185-1e-10671.59% (264) NTP pyrophosphohydrolase
M. ulcerans Agy99MUL_4962-6e-0530.00% (140) hypothetical protein MUL_4962
M. vanbaalenii PYR-1Mvan_5431-1e-10067.28% (272) NUDIX hydrolase

CLUSTAL 2.0.9 multiple sequence alignment


TH_0961|M.thermoresistible__bu      ------------------VRWERERSRLAPDAAPPWLKQLVDNVDHIRRA
MSMEG_6185|M.smegmatis_MC2_155      --------------------MSSTPEGLVPDAAPPWLRPLLDNVGHVPNA
Mflv_1375|M.gilvum_PYR-GCK          ------------------MSWDSREGELIPSAAPPWLAPLVDQPGAVKNA
Mvan_5431|M.vanbaalenii_PYR-1       ------------------MSWDSREGELTPSAAPPWLAPLVDRPGAVKDA
MLBr_02299|M.leprae_Br4923          ----------MPVSAGC-TARVQGTVPLVFDVGPSWLRPLVDNIAVMPGV
MMAR_5160|M.marinum_M               MTSAWPNLPDRPDQPDK-EAPVNATVALTPEVGPSWLRPLVDNIDRVPDA
Mb3696c|M.bovis_AF2122/97           -----MSAGGTPLQAGATPTGSRGTVALRPDAGPSWLRPLVDNVGQIPDA
Rv3672c|M.tuberculosis_H37Rv        -----MSAGGTPLQAGATPTGSRGTVALRPDAGPSWLRPLVDNVGQIPDA
MAV_0457|M.avium_104                -----MSAGGSPLRNGD-PAPARGTVPLTPDACPSWLRPLVDNVDDVPDA
MAB_0420|M.abscessus_ATCC_1997      -----------MTADEPFARRGLATAPLSPDAAPDWMRPLVDNAASVKDI
MUL_4962|M.ulcerans_Agy99           ---------------MTITYDEALRLRIRARLTSHERRAVTDPTKRHAAV
                                                               :     .     : *        

TH_0961|M.thermoresistible__bu      YRRRLPAEVVSAILEADAEADRAAGRDTSGPAGKPKRDAAVLVLFSGPPD
MSMEG_6185|M.smegmatis_MC2_155      YRRRVPPEVLASIVEANHQAAETGSR----------RDAAVLVLFSGPPD
Mflv_1375|M.gilvum_PYR-GCK          YRRRVPAEVLAALTAASTTAAVTGTR----------RDAAVLVLFSGPEE
Mvan_5431|M.vanbaalenii_PYR-1       YRRRVPAEVLAALTAANATAAVTGAR----------RDAAVLVLFSGPQE
MLBr_02299|M.leprae_Br4923          YQRLLPADVLAIVTAARAIPS-VALRRDG-------REAAVLVLFSGPES
MMAR_5160|M.marinum_M               VRRRLPADVLAMVTAASST---ASLRRDE-------RDAAVLVLFSGPES
Mb3696c|M.bovis_AF2122/97           YRRRLPADVLAMVTAAGAVSAMTSSRRDH-------REAAVLVLFSGPEA
Rv3672c|M.tuberculosis_H37Rv        YRRRLPADVLAMVTAAGAVSAMTSSRRDH-------REAAVLVLFSGPEA
MAV_0457|M.avium_104                ARRRLPADVLAMITTK-AASALTSVRGAA-------REAAVLVLFSGPES
MAB_0420|M.abscessus_ATCC_1997      YGRGVHPAVKAILQARKLPSS--------------GRPAAVLVLVSADG-
MUL_4962|M.ulcerans_Agy99           AVVLVDSEVGEDRVDPAPVDEWIGGR-----------------LMPEPGL
                                        : . *                                  *..    

TH_0961|M.thermoresistible__bu      A-PAGELPDDADLLLTVRASTLRHHAGQAAFPGGAADDTDPDPVYTALRE
MSMEG_6185|M.smegmatis_MC2_155      A-PAGVLPDDADLLVTVRASTLRHHAGQAAFPGGATDPGDTGPVATAFRE
Mflv_1375|M.gilvum_PYR-GCK          G-ERGTLPEHADLLVTVRAATLRHHAGQAAFPGGAADPDDRSPVHTALRE
Mvan_5431|M.vanbaalenii_PYR-1       G-SRGTLPDDADLLVTVRASTLRHHAGQAAFPGGAADPGDQSPVHTALRE
MLBr_02299|M.leprae_Br4923          GPPDGGAPDDADLLLTVRASTLRHHAGQAAFPGGASDPTDDGPVATALRE
MMAR_5160|M.marinum_M               --ADGRVPTDADLLLTVRASTLRHHAGQAAFPGGASDPGDDGPVATALRE
Mb3696c|M.bovis_AF2122/97           GPGDGGVPDDADLLLTVRASTLRHHAGQAAFPGGVVDPADDGPVATALRE
Rv3672c|M.tuberculosis_H37Rv        GPGDGGVPDDADLLLTVRASTLRHHAGQAAFPGGVVDPADDGPVATALRE
MAV_0457|M.avium_104                GPPGGGPPTDADLLVTVRASTLRHHAGQAAFPGGAADPTDDGPVATALRE
MAB_0420|M.abscessus_ATCC_1997      ---AVTDPTEADLLLTVRASTLRQHSGQVSFPGGATDPGDGGPVGTALRE
MUL_4962|M.ulcerans_Agy99           DGRMVDVSGGAAFFLCRRASRLRAHAAQWALPGGRVDPGEN-AIEAALRE
                                           .  * :::  **: ** *:.* ::***  *  :  .: :*:**

TH_0961|M.thermoresistible__bu      AAEETGIDTARLQPLATMEKMFIPPSGFHVVPVLAYSPDPGPVGVVDPAE
MSMEG_6185|M.smegmatis_MC2_155      ATEETGVDTSRLHPLATLDKMFIPPSGFHVVPVLAYSPDPGPVTVVDEAE
Mflv_1375|M.gilvum_PYR-GCK          AAEETGLDAGRLRPLATLEKMFIPPSGFHVVPVLAYSADPGPVDVVDTSE
Mvan_5431|M.vanbaalenii_PYR-1       AAEETGIEAGRLQPLATLEKMFIPPSGFHVVPVLAYSPDPGPVAVVDESE
MLBr_02299|M.leprae_Br4923          AHEETGIDLARLHPLATLERMFIAPSRFHVVPVLAYSADPGPVAVVNEAE
MMAR_5160|M.marinum_M               AHEETGLDVSRLHPLVTMERTFIAPSRFHVVPVLAYSADPGPVNVINEAE
Mb3696c|M.bovis_AF2122/97           ANEETGIDPSRLHPLATMERTFIAPSRFHVVPVLAYSPDPGPVAVVNEAE
Rv3672c|M.tuberculosis_H37Rv        ANEETGIDPSRLHPLATMERTFIAPSRFHVVPVLAYSPDPGPVAVVNEAE
MAV_0457|M.avium_104                AREETGIDVSRLHPLATMEKMFIAPSQFHVVPVLAYSPDPGPVAVVNEAE
MAB_0420|M.abscessus_ATCC_1997      AQEETGLDPARVQPLTVMESLFIPPSGFHVSPVLAYSPDPGPVLAVDPGE
MUL_4962|M.ulcerans_Agy99           LDEEIGIRLPDSAVLGLLD-DYPTRSGYVITPVVIWGGGRLDPHLVP-DE
                                      ** *:       *  ::  : . * : : **: :. .      :   *

TH_0961|M.thermoresistible__bu      AALVSRIPVRAFVNPENRIMVHRDARTHRLAWPAFVLNEMLVWGFTGQVI
MSMEG_6185|M.smegmatis_MC2_155      TAAVSRVPVRAFINPENRLMVYREGNTSRFAGPAFLLNEMLVWGFTGQVI
Mflv_1375|M.gilvum_PYR-GCK          TAHVARVPVRAFVNPENRIMVYRDENTRRTAGPAFLLNEMLVWGFTGQVI
Mvan_5431|M.vanbaalenii_PYR-1       TALVARVPVRAFINPENRIMVYRRQNTRRAAGPAFLLNQMMVWGFTGQVI
MLBr_02299|M.leprae_Br4923          TAIVARVPLCAFINPANRLMVYRRAHGHRWYGPAFLLNDMLVWGFTGQVI
MMAR_5160|M.marinum_M               TAIVARVPVRAFINPANRLMVYRRTLSRRWAGPAFLLNQMLVWGFTGQVI
Mb3696c|M.bovis_AF2122/97           TAIVARVPVRAFINPANRLMVYRRPHTRRWAGPAFLLNQMLVWGFTGQVI
Rv3672c|M.tuberculosis_H37Rv        TAIVARVPVRAFINPANRLMVYRRPHTRRWAGPAFLLNQMLVWGFTGQVI
MAV_0457|M.avium_104                TALVARVPLRAFINPANRLMVYRGDLGRRWAGPAFLLNEMLVWGFTGQVI
MAB_0420|M.abscessus_ATCC_1997      TAEVSRVKIGDLVDPTNRIMVTKKTFGIRYSGPAFLLPGMLVWGFTGQII
MUL_4962|M.ulcerans_Agy99           VVAVYRVGLHQLQRQDSPRFVAIPESPR--PVVQVPLGNDLIHAPTG---
                                    .. * *: :  :    .  :*             . *   :: . **   

TH_0961|M.thermoresistible__bu      SAMLDVAGWARPWNTDDVRELDEAMALAGSPDRSPGRYGDAHDD---
MSMEG_6185|M.smegmatis_MC2_155      SAMLDVAGWAKPWNTDDVRGLEEAMALVG---RASS-YGEAHRGTGI
Mflv_1375|M.gilvum_PYR-GCK          SAMLDVAGWAVPWENDKLYELRDAMALLD----AEDSYGEAQR----
Mvan_5431|M.vanbaalenii_PYR-1       AAMLDVAGWAVPWESDKVYELDEAMALLD----AEGSYGDAQR----
MLBr_02299|M.leprae_Br4923          AAMLDVAGWAQSWDVTDVREVGEAMALVD-------SQGDPR-----
MMAR_5160|M.marinum_M               SAVLDVAGWSEPWDTSDLRELDDAMALVG-------EQGGLR-----
Mb3696c|M.bovis_AF2122/97           SAVLDVAGWAQPWDTGDIRELDAAMVLID-------DESDPR-----
Rv3672c|M.tuberculosis_H37Rv        SAVLDVAGWAQPWDTGDIRELDAAMVLID-------DESDPR-----
MAV_0457|M.avium_104                SALLDVAGWAQPWDTSDQRELDAAMALVG-------ERGDALE----
MAB_0420|M.abscessus_ATCC_1997      SAMLEVSGWAQPWDTHNLRDLDELLAEHLG--------GSV------
MUL_4962|M.ulcerans_Agy99           AVLLQVRWLCLEGRDDPVDELEQPVFAWK------------------
                                    :.:*:*   .          :   :