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VSWDSREGELIPSAAPPWLAPLVDQPGAVKNAYRRRVPAEVLAALTAASTTAAVTGTRRDAAVLVLFSGP EEGERGTLPEHADLLVTVRAATLRHHAGQAAFPGGAADPDDRSPVHTALREAAEETGLDAGRLRPLATLE KMFIPPSGFHVVPVLAYSADPGPVDVVDTSETAHVARVPVRAFVNPENRIMVYRDENTRRTAGPAFLLNE MLVWGFTGQVISAMLDVAGWAVPWENDKLYELRDAMALLDAEDSYGEAQR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1375 | - | - | 100% (260) | NUDIX hydrolase |
| M. gilvum PYR-GCK | Mflv_1043 | - | 5e-05 | 29.75% (121) | NUDIX hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3696c | - | 4e-91 | 68.42% (247) | hypothetical protein Mb3696c |
| M. tuberculosis H37Rv | Rv3672c | - | 4e-91 | 68.42% (247) | hypothetical protein Rv3672c |
| M. leprae Br4923 | MLBr_02299 | - | 2e-83 | 64.23% (246) | hypothetical protein MLBr_02299 |
| M. abscessus ATCC 19977 | MAB_0420 | - | 3e-66 | 56.30% (238) | hypothetical protein MAB_0420 |
| M. marinum M | MMAR_5160 | - | 2e-90 | 69.17% (240) | hypothetical protein MMAR_5160 |
| M. avium 104 | MAV_0457 | - | 7e-89 | 69.96% (243) | hydrolase, nudix family protein |
| M. smegmatis MC2 155 | MSMEG_6185 | - | 1e-104 | 73.71% (251) | NTP pyrophosphohydrolase |
| M. thermoresistible (build 8) | TH_0961 | - | 1e-95 | 64.71% (272) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4962 | - | 1e-06 | 28.00% (150) | hypothetical protein MUL_4962 |
| M. vanbaalenii PYR-1 | Mvan_5431 | - | 1e-131 | 87.31% (260) | NUDIX hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1375|M.gilvum_PYR-GCK ------------------MSWDSREGELIPSAAPPWLAPLVDQPGAVKNA
Mvan_5431|M.vanbaalenii_PYR-1 ------------------MSWDSREGELTPSAAPPWLAPLVDRPGAVKDA
MSMEG_6185|M.smegmatis_MC2_155 --------------------MSSTPEGLVPDAAPPWLRPLLDNVGHVPNA
TH_0961|M.thermoresistible__bu ------------------VRWERERSRLAPDAAPPWLKQLVDNVDHIRRA
MLBr_02299|M.leprae_Br4923 ----------MPVSAGC-TARVQGTVPLVFDVGPSWLRPLVDNIAVMPGV
MMAR_5160|M.marinum_M MTSAWPNLPDRPDQPDK-EAPVNATVALTPEVGPSWLRPLVDNIDRVPDA
Mb3696c|M.bovis_AF2122/97 -----MSAGGTPLQAGATPTGSRGTVALRPDAGPSWLRPLVDNVGQIPDA
Rv3672c|M.tuberculosis_H37Rv -----MSAGGTPLQAGATPTGSRGTVALRPDAGPSWLRPLVDNVGQIPDA
MAV_0457|M.avium_104 -----MSAGGSPLRNGD-PAPARGTVPLTPDACPSWLRPLVDNVDDVPDA
MAB_0420|M.abscessus_ATCC_1997 -----------MTADEPFARRGLATAPLSPDAAPDWMRPLVDNAASVKDI
MUL_4962|M.ulcerans_Agy99 ---------------MTITYDEALRLRIRARLTSHERRAVTDPTKRHAAV
: . : *
Mflv_1375|M.gilvum_PYR-GCK YRRRVPAEVLAALTAASTTAAVTGTR----------RDAAVLVLFSGPEE
Mvan_5431|M.vanbaalenii_PYR-1 YRRRVPAEVLAALTAANATAAVTGAR----------RDAAVLVLFSGPQE
MSMEG_6185|M.smegmatis_MC2_155 YRRRVPPEVLASIVEANHQAAETGSR----------RDAAVLVLFSGPPD
TH_0961|M.thermoresistible__bu YRRRLPAEVVSAILEADAEADRAAGRDTSGPAGKPKRDAAVLVLFSGPPD
MLBr_02299|M.leprae_Br4923 YQRLLPADVLAIVTAARAIPS-VALRRDG-------REAAVLVLFSGPES
MMAR_5160|M.marinum_M VRRRLPADVLAMVTAASST---ASLRRDE-------RDAAVLVLFSGPES
Mb3696c|M.bovis_AF2122/97 YRRRLPADVLAMVTAAGAVSAMTSSRRDH-------REAAVLVLFSGPEA
Rv3672c|M.tuberculosis_H37Rv YRRRLPADVLAMVTAAGAVSAMTSSRRDH-------REAAVLVLFSGPEA
MAV_0457|M.avium_104 ARRRLPADVLAMITTK-AASALTSVRGAA-------REAAVLVLFSGPES
MAB_0420|M.abscessus_ATCC_1997 YGRGVHPAVKAILQARKLPSS--------------GRPAAVLVLVSADG-
MUL_4962|M.ulcerans_Agy99 AVVLVDSEVGEDRVDPAPVDEWIGGR-----------------LMPEPGL
: . * *..
Mflv_1375|M.gilvum_PYR-GCK G-ERGTLPEHADLLVTVRAATLRHHAGQAAFPGGAADPDDRSPVHTALRE
Mvan_5431|M.vanbaalenii_PYR-1 G-SRGTLPDDADLLVTVRASTLRHHAGQAAFPGGAADPGDQSPVHTALRE
MSMEG_6185|M.smegmatis_MC2_155 A-PAGVLPDDADLLVTVRASTLRHHAGQAAFPGGATDPGDTGPVATAFRE
TH_0961|M.thermoresistible__bu A-PAGELPDDADLLLTVRASTLRHHAGQAAFPGGAADDTDPDPVYTALRE
MLBr_02299|M.leprae_Br4923 GPPDGGAPDDADLLLTVRASTLRHHAGQAAFPGGASDPTDDGPVATALRE
MMAR_5160|M.marinum_M --ADGRVPTDADLLLTVRASTLRHHAGQAAFPGGASDPGDDGPVATALRE
Mb3696c|M.bovis_AF2122/97 GPGDGGVPDDADLLLTVRASTLRHHAGQAAFPGGVVDPADDGPVATALRE
Rv3672c|M.tuberculosis_H37Rv GPGDGGVPDDADLLLTVRASTLRHHAGQAAFPGGVVDPADDGPVATALRE
MAV_0457|M.avium_104 GPPGGGPPTDADLLVTVRASTLRHHAGQAAFPGGAADPTDDGPVATALRE
MAB_0420|M.abscessus_ATCC_1997 ---AVTDPTEADLLLTVRASTLRQHSGQVSFPGGATDPGDGGPVGTALRE
MUL_4962|M.ulcerans_Agy99 DGRMVDVSGGAAFFLCRRASRLRAHAAQWALPGGRVDPGEN-AIEAALRE
. * ::: **: ** *:.* ::*** * : .: :*:**
Mflv_1375|M.gilvum_PYR-GCK AAEETGLDAGRLRPLATLEKMFIPPSGFHVVPVLAYSADPGPVDVVDTSE
Mvan_5431|M.vanbaalenii_PYR-1 AAEETGIEAGRLQPLATLEKMFIPPSGFHVVPVLAYSPDPGPVAVVDESE
MSMEG_6185|M.smegmatis_MC2_155 ATEETGVDTSRLHPLATLDKMFIPPSGFHVVPVLAYSPDPGPVTVVDEAE
TH_0961|M.thermoresistible__bu AAEETGIDTARLQPLATMEKMFIPPSGFHVVPVLAYSPDPGPVGVVDPAE
MLBr_02299|M.leprae_Br4923 AHEETGIDLARLHPLATLERMFIAPSRFHVVPVLAYSADPGPVAVVNEAE
MMAR_5160|M.marinum_M AHEETGLDVSRLHPLVTMERTFIAPSRFHVVPVLAYSADPGPVNVINEAE
Mb3696c|M.bovis_AF2122/97 ANEETGIDPSRLHPLATMERTFIAPSRFHVVPVLAYSPDPGPVAVVNEAE
Rv3672c|M.tuberculosis_H37Rv ANEETGIDPSRLHPLATMERTFIAPSRFHVVPVLAYSPDPGPVAVVNEAE
MAV_0457|M.avium_104 AREETGIDVSRLHPLATMEKMFIAPSQFHVVPVLAYSPDPGPVAVVNEAE
MAB_0420|M.abscessus_ATCC_1997 AQEETGLDPARVQPLTVMESLFIPPSGFHVSPVLAYSPDPGPVLAVDPGE
MUL_4962|M.ulcerans_Agy99 LDEEIGIRLPDSAVLGLLD-DYPTRSGYVITPVVIWGGGRLDPHLVP-DE
** *: * :: : . * : : **: :. . : *
Mflv_1375|M.gilvum_PYR-GCK TAHVARVPVRAFVNPENRIMVYRDENTRRTAGPAFLLNEMLVWGFTGQVI
Mvan_5431|M.vanbaalenii_PYR-1 TALVARVPVRAFINPENRIMVYRRQNTRRAAGPAFLLNQMMVWGFTGQVI
MSMEG_6185|M.smegmatis_MC2_155 TAAVSRVPVRAFINPENRLMVYREGNTSRFAGPAFLLNEMLVWGFTGQVI
TH_0961|M.thermoresistible__bu AALVSRIPVRAFVNPENRIMVHRDARTHRLAWPAFVLNEMLVWGFTGQVI
MLBr_02299|M.leprae_Br4923 TAIVARVPLCAFINPANRLMVYRRAHGHRWYGPAFLLNDMLVWGFTGQVI
MMAR_5160|M.marinum_M TAIVARVPVRAFINPANRLMVYRRTLSRRWAGPAFLLNQMLVWGFTGQVI
Mb3696c|M.bovis_AF2122/97 TAIVARVPVRAFINPANRLMVYRRPHTRRWAGPAFLLNQMLVWGFTGQVI
Rv3672c|M.tuberculosis_H37Rv TAIVARVPVRAFINPANRLMVYRRPHTRRWAGPAFLLNQMLVWGFTGQVI
MAV_0457|M.avium_104 TALVARVPLRAFINPANRLMVYRGDLGRRWAGPAFLLNEMLVWGFTGQVI
MAB_0420|M.abscessus_ATCC_1997 TAEVSRVKIGDLVDPTNRIMVTKKTFGIRYSGPAFLLPGMLVWGFTGQII
MUL_4962|M.ulcerans_Agy99 VVAVYRVGLHQLQRQDSPRFVAIPESPR--PVVQVPLGNDLIHAPTG---
.. * *: : : . :* . * :: . **
Mflv_1375|M.gilvum_PYR-GCK SAMLDVAGWAVPWENDKLYELRDAMALLD----AEDSYGEAQR----
Mvan_5431|M.vanbaalenii_PYR-1 AAMLDVAGWAVPWESDKVYELDEAMALLD----AEGSYGDAQR----
MSMEG_6185|M.smegmatis_MC2_155 SAMLDVAGWAKPWNTDDVRGLEEAMALVG---RASS-YGEAHRGTGI
TH_0961|M.thermoresistible__bu SAMLDVAGWARPWNTDDVRELDEAMALAGSPDRSPGRYGDAHDD---
MLBr_02299|M.leprae_Br4923 AAMLDVAGWAQSWDVTDVREVGEAMALVD-------SQGDPR-----
MMAR_5160|M.marinum_M SAVLDVAGWSEPWDTSDLRELDDAMALVG-------EQGGLR-----
Mb3696c|M.bovis_AF2122/97 SAVLDVAGWAQPWDTGDIRELDAAMVLID-------DESDPR-----
Rv3672c|M.tuberculosis_H37Rv SAVLDVAGWAQPWDTGDIRELDAAMVLID-------DESDPR-----
MAV_0457|M.avium_104 SALLDVAGWAQPWDTSDQRELDAAMALVG-------ERGDALE----
MAB_0420|M.abscessus_ATCC_1997 SAMLEVSGWAQPWDTHNLRDLDELLAEHLG--------GSV------
MUL_4962|M.ulcerans_Agy99 AVLLQVRWLCLEGRDDPVDELEQPVFAWK------------------
:.:*:* . : :