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VSAGGSPLRNGDPAPARGTVPLTPDACPSWLRPLVDNVDDVPDAARRRLPADVLAMITTKAASALTSVRG AAREAAVLVLFSGPESGPPGGGPPTDADLLVTVRASTLRHHAGQAAFPGGAADPTDDGPVATALREAREE TGIDVSRLHPLATMEKMFIAPSQFHVVPVLAYSPDPGPVAVVNEAETALVARVPLRAFINPANRLMVYRG DLGRRWAGPAFLLNEMLVWGFTGQVISALLDVAGWAQPWDTSDQRELDAAMALVGERGDALE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0457 | - | - | 100% (272) | hydrolase, nudix family protein |
| M. avium 104 | MAV_4227 | - | 2e-05 | 30.72% (153) | hydrolase, nudix family protein, putative |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3696c | - | 1e-119 | 79.34% (271) | hypothetical protein Mb3696c |
| M. gilvum PYR-GCK | Mflv_1375 | - | 8e-89 | 69.96% (243) | NUDIX hydrolase |
| M. tuberculosis H37Rv | Rv3672c | - | 1e-119 | 79.34% (271) | hypothetical protein Rv3672c |
| M. leprae Br4923 | MLBr_02299 | - | 1e-110 | 74.52% (263) | hypothetical protein MLBr_02299 |
| M. abscessus ATCC 19977 | MAB_0420 | - | 3e-72 | 54.94% (253) | hypothetical protein MAB_0420 |
| M. marinum M | MMAR_5160 | - | 1e-114 | 80.00% (255) | hypothetical protein MMAR_5160 |
| M. smegmatis MC2 155 | MSMEG_6185 | - | 7e-97 | 73.36% (244) | NTP pyrophosphohydrolase |
| M. thermoresistible (build 8) | TH_0961 | - | 3e-90 | 68.65% (252) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_5431 | - | 5e-95 | 71.83% (252) | NUDIX hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1375|M.gilvum_PYR-GCK ------------------MSWDSREGELIPSAAPPWLAPLVDQPGAVKNA
Mvan_5431|M.vanbaalenii_PYR-1 ------------------MSWDSREGELTPSAAPPWLAPLVDRPGAVKDA
MSMEG_6185|M.smegmatis_MC2_155 --------------------MSSTPEGLVPDAAPPWLRPLLDNVGHVPNA
TH_0961|M.thermoresistible__bu ------------------VRWERERSRLAPDAAPPWLKQLVDNVDHIRRA
Mb3696c|M.bovis_AF2122/97 -----MSAGGTPLQAGATPTGSRGTVALRPDAGPSWLRPLVDNVGQIPDA
Rv3672c|M.tuberculosis_H37Rv -----MSAGGTPLQAGATPTGSRGTVALRPDAGPSWLRPLVDNVGQIPDA
MAV_0457|M.avium_104 -----MSAGGSPLRNGD-PAPARGTVPLTPDACPSWLRPLVDNVDDVPDA
MLBr_02299|M.leprae_Br4923 ----------MPVSAGC-TARVQGTVPLVFDVGPSWLRPLVDNIAVMPGV
MMAR_5160|M.marinum_M MTSAWPNLPDRPDQPDK-EAPVNATVALTPEVGPSWLRPLVDNIDRVPDA
MAB_0420|M.abscessus_ATCC_1997 -----------MTADEPFARRGLATAPLSPDAAPDWMRPLVDNAASVKDI
* .. * *: *:*. :
Mflv_1375|M.gilvum_PYR-GCK YRRRVPAEVLAALTAASTTAAVTGTR----------RDAAVLVLFSGPEE
Mvan_5431|M.vanbaalenii_PYR-1 YRRRVPAEVLAALTAANATAAVTGAR----------RDAAVLVLFSGPQE
MSMEG_6185|M.smegmatis_MC2_155 YRRRVPPEVLASIVEANHQAAETGSR----------RDAAVLVLFSGPPD
TH_0961|M.thermoresistible__bu YRRRLPAEVVSAILEADAEADRAAGRDTSGPAGKPKRDAAVLVLFSGPPD
Mb3696c|M.bovis_AF2122/97 YRRRLPADVLAMVTAAGAVSAMTSSRRDH-------REAAVLVLFSGPEA
Rv3672c|M.tuberculosis_H37Rv YRRRLPADVLAMVTAAGAVSAMTSSRRDH-------REAAVLVLFSGPEA
MAV_0457|M.avium_104 ARRRLPADVLAMITTK-AASALTSVRGAA-------REAAVLVLFSGPES
MLBr_02299|M.leprae_Br4923 YQRLLPADVLAIVTAARAIPS-VALRRDG-------REAAVLVLFSGPES
MMAR_5160|M.marinum_M VRRRLPADVLAMVTAASST---ASLRRDE-------RDAAVLVLFSGPES
MAB_0420|M.abscessus_ATCC_1997 YGRGVHPAVKAILQARKLPSS--------------GRPAAVLVLVSADG-
* : . * : : * ******.*.
Mflv_1375|M.gilvum_PYR-GCK G-ERGTLPEHADLLVTVRAATLRHHAGQAAFPGGAADPDDRSPVHTALRE
Mvan_5431|M.vanbaalenii_PYR-1 G-SRGTLPDDADLLVTVRASTLRHHAGQAAFPGGAADPGDQSPVHTALRE
MSMEG_6185|M.smegmatis_MC2_155 A-PAGVLPDDADLLVTVRASTLRHHAGQAAFPGGATDPGDTGPVATAFRE
TH_0961|M.thermoresistible__bu A-PAGELPDDADLLLTVRASTLRHHAGQAAFPGGAADDTDPDPVYTALRE
Mb3696c|M.bovis_AF2122/97 GPGDGGVPDDADLLLTVRASTLRHHAGQAAFPGGVVDPADDGPVATALRE
Rv3672c|M.tuberculosis_H37Rv GPGDGGVPDDADLLLTVRASTLRHHAGQAAFPGGVVDPADDGPVATALRE
MAV_0457|M.avium_104 GPPGGGPPTDADLLVTVRASTLRHHAGQAAFPGGAADPTDDGPVATALRE
MLBr_02299|M.leprae_Br4923 GPPDGGAPDDADLLLTVRASTLRHHAGQAAFPGGASDPTDDGPVATALRE
MMAR_5160|M.marinum_M --ADGRVPTDADLLLTVRASTLRHHAGQAAFPGGASDPGDDGPVATALRE
MAB_0420|M.abscessus_ATCC_1997 ---AVTDPTEADLLLTVRASTLRQHSGQVSFPGGATDPGDGGPVGTALRE
* .****:****:***:*:**.:****. * * .** **:**
Mflv_1375|M.gilvum_PYR-GCK AAEETGLDAGRLRPLATLEKMFIPPSGFHVVPVLAYSADPGPVDVVDTSE
Mvan_5431|M.vanbaalenii_PYR-1 AAEETGIEAGRLQPLATLEKMFIPPSGFHVVPVLAYSPDPGPVAVVDESE
MSMEG_6185|M.smegmatis_MC2_155 ATEETGVDTSRLHPLATLDKMFIPPSGFHVVPVLAYSPDPGPVTVVDEAE
TH_0961|M.thermoresistible__bu AAEETGIDTARLQPLATMEKMFIPPSGFHVVPVLAYSPDPGPVGVVDPAE
Mb3696c|M.bovis_AF2122/97 ANEETGIDPSRLHPLATMERTFIAPSRFHVVPVLAYSPDPGPVAVVNEAE
Rv3672c|M.tuberculosis_H37Rv ANEETGIDPSRLHPLATMERTFIAPSRFHVVPVLAYSPDPGPVAVVNEAE
MAV_0457|M.avium_104 AREETGIDVSRLHPLATMEKMFIAPSQFHVVPVLAYSPDPGPVAVVNEAE
MLBr_02299|M.leprae_Br4923 AHEETGIDLARLHPLATLERMFIAPSRFHVVPVLAYSADPGPVAVVNEAE
MMAR_5160|M.marinum_M AHEETGLDVSRLHPLVTMERTFIAPSRFHVVPVLAYSADPGPVNVINEAE
MAB_0420|M.abscessus_ATCC_1997 AQEETGLDPARVQPLTVMESLFIPPSGFHVSPVLAYSPDPGPVLAVDPGE
* ****:: .*::**..:: **.** *** ******.***** .:: .*
Mflv_1375|M.gilvum_PYR-GCK TAHVARVPVRAFVNPENRIMVYRDENTRRTAGPAFLLNEMLVWGFTGQVI
Mvan_5431|M.vanbaalenii_PYR-1 TALVARVPVRAFINPENRIMVYRRQNTRRAAGPAFLLNQMMVWGFTGQVI
MSMEG_6185|M.smegmatis_MC2_155 TAAVSRVPVRAFINPENRLMVYREGNTSRFAGPAFLLNEMLVWGFTGQVI
TH_0961|M.thermoresistible__bu AALVSRIPVRAFVNPENRIMVHRDARTHRLAWPAFVLNEMLVWGFTGQVI
Mb3696c|M.bovis_AF2122/97 TAIVARVPVRAFINPANRLMVYRRPHTRRWAGPAFLLNQMLVWGFTGQVI
Rv3672c|M.tuberculosis_H37Rv TAIVARVPVRAFINPANRLMVYRRPHTRRWAGPAFLLNQMLVWGFTGQVI
MAV_0457|M.avium_104 TALVARVPLRAFINPANRLMVYRGDLGRRWAGPAFLLNEMLVWGFTGQVI
MLBr_02299|M.leprae_Br4923 TAIVARVPLCAFINPANRLMVYRRAHGHRWYGPAFLLNDMLVWGFTGQVI
MMAR_5160|M.marinum_M TAIVARVPVRAFINPANRLMVYRRTLSRRWAGPAFLLNQMLVWGFTGQVI
MAB_0420|M.abscessus_ATCC_1997 TAEVSRVKIGDLVDPTNRIMVTKKTFGIRYSGPAFLLPGMLVWGFTGQII
:* *:*: : :::* **:** : * ***:* *:*******:*
Mflv_1375|M.gilvum_PYR-GCK SAMLDVAGWAVPWENDKLYELRDAMALLD----AEDSYGEAQR----
Mvan_5431|M.vanbaalenii_PYR-1 AAMLDVAGWAVPWESDKVYELDEAMALLD----AEGSYGDAQR----
MSMEG_6185|M.smegmatis_MC2_155 SAMLDVAGWAKPWNTDDVRGLEEAMALVG---RASS-YGEAHRGTGI
TH_0961|M.thermoresistible__bu SAMLDVAGWARPWNTDDVRELDEAMALAGSPDRSPGRYGDAHDD---
Mb3696c|M.bovis_AF2122/97 SAVLDVAGWAQPWDTGDIRELDAAMVLID-------DESDPR-----
Rv3672c|M.tuberculosis_H37Rv SAVLDVAGWAQPWDTGDIRELDAAMVLID-------DESDPR-----
MAV_0457|M.avium_104 SALLDVAGWAQPWDTSDQRELDAAMALVG-------ERGDALE----
MLBr_02299|M.leprae_Br4923 AAMLDVAGWAQSWDVTDVREVGEAMALVD-------SQGDPR-----
MMAR_5160|M.marinum_M SAVLDVAGWSEPWDTSDLRELDDAMALVG-------EQGGLR-----
MAB_0420|M.abscessus_ATCC_1997 SAMLEVSGWAQPWDTHNLRDLDELLAEHLG--------GSV------
:*:*:*:**: .*: . : :. .