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M. thermoresistible (build 8) TH_0940 (galU)

annotation: PROBABLE UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE GALU (UDP-GLUCOSE PYROPHOSPHORYLASE) (UDPGP) (ALPHA-D-GLUCOSYL-1-PHOSPHATE URIDYLYLTRANSFERASE) (URIDINE DIPHOSPHOGLUCOSE PYROPHOSPHORYLASE)
coordinates: 1869830 - 1870735
length: 302

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0940galU-100% (302)PROBABLE UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE GALU (UDP-GLUCOSE PYROPHOSPHORYLASE) (UDPGP) (ALPHA-D-GLUCOSYL-1-PHOSPHATE URIDYLYLTRANSFERASE) (URIDINE DIPHOSPHOGLUCOSE PYROPHOSPHORYLASE)
M. thermoresistible (build 8)TH_1924rmlA3e-1427.49% (251) ALPHA-D-GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE RMLA
M. thermoresistible (build 8)TH_0779rmlA27e-1225.74% (272) D-ALPHA-D-MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE MANB

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1020galU1e-13980.26% (304) UTP--glucose-1-phosphate uridylyltransferase GalU
M. gilvum PYR-GCKMflv_1897-1e-14986.33% (300) nucleotidyl transferase
M. tuberculosis H37RvRv0993galU1e-13879.93% (304) UTP--glucose-1-phosphate uridylyltransferase GalU
M. leprae Br4923MLBr_00182galU1e-14181.14% (297) putative UTP-glucose-1-phosphate uridylyltransferase
M. abscessus ATCC 19977MAB_1086-1e-14283.90% (292) putative UTP-glucose-1-phosphate uridylyltransferase (GalU)
M. marinum MMMAR_4521galU1e-13981.82% (297) UTP--glucose-1-phosphate uridylyltransferase GalU
M. avium 104MAV_1102-1e-13982.31% (294) GalU protein
M. smegmatis MC2 155MSMEG_5471galU1e-14988.40% (293) UTP-glucose-1-phosphate uridylyltransferase
M. ulcerans Agy99MUL_4693galU1e-13981.48% (297) UTP--glucose-1-phosphate uridylyltransferase GalU
M. vanbaalenii PYR-1Mvan_4833-1e-15086.00% (300) nucleotidyl transferase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_4521|M.marinum_M               ----MSQEVAIPFTAIVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA
MUL_4693|M.ulcerans_Agy99           ----MSQEVAIPFTAIVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA
Mb1020|M.bovis_AF2122/97            ---MSRPEVLTPFTAIVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA
Rv0993|M.tuberculosis_H37Rv         ---MSRPEVLTPFTAIVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA
MLBr_00182|M.leprae_Br4923          MSLLLSAQVPIPFTAIVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA
MAV_1102|M.avium_104                --------MVVPRTAIVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA
TH_0940|M.thermoresistible__bu      ---MSESRAPVPRTAVVPAAGLGTRFLPVTKTVPKELLPVVDTPGIELVA
MSMEG_5471|M.smegmatis_MC2_155      ---MS-----IPHTAVVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA
Mflv_1897|M.gilvum_PYR-GCK          ---MNRPEVPVPRTAVVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA
Mvan_4833|M.vanbaalenii_PYR-1       ---MNRAEVPIPRTAVVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA
MAB_1086|M.abscessus_ATCC_1997      ---MTGPDVLIPRTAVVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA
                                               * **:************.*********************

MMAR_4521|M.marinum_M               AEAAAAGAERLVIVTSEGKDGVVAHFVEDLVLEGTLEARGKTAMLAKVRR
MUL_4693|M.ulcerans_Agy99           AEAAAAGAERLVIVTSEGKDGVVAHFVEDLVLEGTLEARGKTAMLAKVRR
Mb1020|M.bovis_AF2122/97            AEAAAAGAERLVIVTSEGKDGVVAHFVEDLVLEGTLEARGKIAMLAKVRR
Rv0993|M.tuberculosis_H37Rv         AEAAAAGAERLVIVTSEGKDGVVAHFVEDLVLEGTLEARGKIAMLAKVRR
MLBr_00182|M.leprae_Br4923          AEAAAAGAERLVIVTSEGKDGVVAHFVQDLVLEGTLLARGNKAMLAKVRR
MAV_1102|M.avium_104                AEAAEAGAERLVIVTSEGKDGVVAHFVEDLVLESTLEERGKTAMLDKVRR
TH_0940|M.thermoresistible__bu      EEAAEAGAQRLIIITSEGKDSVVAHFVQDLVLEGVLEARGKKTMLEKVRR
MSMEG_5471|M.smegmatis_MC2_155      AEAAEAGAERLVIVTSEGKDGVVAHFVQDLVLEGTLEARGKKTMLEKVRR
Mflv_1897|M.gilvum_PYR-GCK          AEAAEAGAERLIIITSEGKDGVVAHFVEDLVLEGTLEARGKKTMLEKVRR
Mvan_4833|M.vanbaalenii_PYR-1       AEAAEAGAERLIIVTSEGKDGVVAHFVEDLVLEGTLEARGKKTMLEKVRR
MAB_1086|M.abscessus_ATCC_1997      EEAAEAGAERLVIVTSEGKDGVVAHFVEDLVLEGTLEARGKHAMLEKVRK
                                     *** ***:**:*:******.******:*****..*  **: :** ***:

MMAR_4521|M.marinum_M               APALIKVESVVQAEPLGLGHAISCVEPTLSDDEDAVSVLLPDDLVLPTGV
MUL_4693|M.ulcerans_Agy99           APALIKVESVVQAEPLGLGHAISCVEPTLSDDEDAVSVLLPDDLVLPTGV
Mb1020|M.bovis_AF2122/97            APALIKVESVVQAEPLGLGHAIGCVEPTLSPDEDAVAVLLPDDLVLPTGV
Rv0993|M.tuberculosis_H37Rv         APALIKVESVVQAEPLGLGHAIGCVEPTLSPDEDAVAVLLPDDLVLPTGV
MLBr_00182|M.leprae_Br4923          APELIKVESVVQAEPLGLGHAIGCAEPTLAPDEDAVSVLLPDDLVLPTGV
MAV_1102|M.avium_104                APRLIKVESVVQSEPLGLGHAIGCVEPRLADDEDAVAVLLPDDLVLPTGV
TH_0940|M.thermoresistible__bu      APELIRVESVIQQEPLGLGHAVSCVESSLEPDEDAIAVLLPDDLVLPTGI
MSMEG_5471|M.smegmatis_MC2_155      APALIKVESVVQAEPLGLGHAVSCVESVLAADEDAISVLLPDDLVLPTGV
Mflv_1897|M.gilvum_PYR-GCK          APALIKVESVVQAEPLGLGHAVGCVEASLAPDEDAIAVLLPDDLVLPTGV
Mvan_4833|M.vanbaalenii_PYR-1       APALIKVESVVQAEPLGLGHAISCVEASLAPDEDAIAVLLPDDLVLPTGV
MAB_1086|M.abscessus_ATCC_1997      APALIKVQSVVQAEPLGLGHAVGCVESVLDDDEDAVAVLLPDDLVWPRGV
                                    ** **:*:**:* ********:.*.*. *  ****::******** * *:

MMAR_4521|M.marinum_M               LETMSKVRARLGGTVLCAIEVSPDEISAYGVFDVEPVPGGEWAANPDVLK
MUL_4693|M.ulcerans_Agy99           LETMSKVRARLGGTVLCAIEVSPDEISAYGVFDVEPVPGGEWAANPNVLK
Mb1020|M.bovis_AF2122/97            LETMSKVRASRGGTVLCAIEVAREEISAYGVFDVEPVPDGDYTDDPNVLK
Rv0993|M.tuberculosis_H37Rv         LETMSKVRASRGGTVLCAIEVAREEISAYGVFDVEPVPDGDYTDDPNVLK
MLBr_00182|M.leprae_Br4923          LETMSKVRASRGGTVLCAIEVASEEISSYGVFDVEPVPGG---DNPNVLK
MAV_1102|M.avium_104                LGTMSKVRAHYGGTVLCAIEVTPEEISAYGVFDVEPVPDD----DPDVLR
TH_0940|M.thermoresistible__bu      LETMSRVRAKRGGSVLCAIEVPGDEISAYGVFDVEPVPDST---NPDVLR
MSMEG_5471|M.smegmatis_MC2_155      LETMSKVRAKRGGSVLCAIEVPGDKISAYGVFDVETVPDAA---NPNVLR
Mflv_1897|M.gilvum_PYR-GCK          LETMAKVRAKRGGSVLCAIEVDREDISAYGVFDVETVPDAA---NPNVLR
Mvan_4833|M.vanbaalenii_PYR-1       LETMSKVRAKRGGSVLCAIEVDREDISAYGVIDVEPLPDAN---NPNVLK
MAB_1086|M.abscessus_ATCC_1997      LETMAKVRAKRGGSVLCAIEVPPHEISSYGAFDVEIVPDAA---NPNVLR
                                    * **::***  **:*******  ..**:**.:*** :*.     :*:**:

MMAR_4521|M.marinum_M               VKGMVEKPKTQDAPSMFAAAGRYVLDRAIFDALRRIERGAGGEVQLTDAI
MUL_4693|M.ulcerans_Agy99           VKGMVEKPKTQDAPSMFAAAGRYVLDRAIFDALRRIERGAGGEVQLTDAI
Mb1020|M.bovis_AF2122/97            VRGMVEKPKAETAPSRYAAAGRYVLDRAIFDALRRIDRGAGGEVQLTDAI
Rv0993|M.tuberculosis_H37Rv         VRGMVEKPKAETAPSRYAAAGRYVLDRAIFDALRRIDQGAGGEVQLTDAI
MLBr_00182|M.leprae_Br4923          VIGMVEKPKAEDAPSTFAAAGRYVLDRAIFDALRRVSRGTGGEVQITDAI
MAV_1102|M.avium_104                VKGMVEKPKAEDAPSMFAAAGRYVLDRAIFDALRRIDRGAGGEVQLTDGI
TH_0940|M.thermoresistible__bu      VKGMVEKPKPEDAPSPYAAAGRYVLDRAIFDALRRVPRGAGGEIQLTDAI
MSMEG_5471|M.smegmatis_MC2_155      VKGMVEKPRPEDAPSHFAAAGRYVLDRAIFDALRRVPRGTGGEIQLTDAI
Mflv_1897|M.gilvum_PYR-GCK          VKGMVEKPKAEDAPSLFAAAGRYILDRAIFDALKRIPRGAGGELQLTDAI
Mvan_4833|M.vanbaalenii_PYR-1       VKGMVEKPKPEDAPSLYAAAGRYVLDRAIFDALRRIPRGAGGELQLTDAI
MAB_1086|M.abscessus_ATCC_1997      VKGMVEKPKTEEAPSNYAAAGRYLLDRAIFDALKRIPRGAGGELQLTDAI
                                    * ******:.: *** :******:*********:*: :*:***:*:**.*

MMAR_4521|M.marinum_M               ALLIAEGHPVHVVVHRGSRHDLGNPGGYLKAAVDFALDRDDYGPDLRRWL
MUL_4693|M.ulcerans_Agy99           ALLIAEGHPVHVVVHRGSRHDLGNPGGYLKAAVDFALDRDDYGPDLRRWL
Mb1020|M.bovis_AF2122/97            ALLIAEGHPVHVVVHQGSRHDLGNPGGYLKAAVDFALDRDDYGPDLRRWL
Rv0993|M.tuberculosis_H37Rv         ALLIAEGHPVHVVVHQGSRHDLGNPGGYLKAAVDFALDRDDYGPDLRRWL
MLBr_00182|M.leprae_Br4923          ALLIKEGHPVHVVVHRGSRHDLGNPGGYLKAAVDFALDRDDYGPDLRRWL
MAV_1102|M.avium_104                ALLISEGHPVHVVVHRGSRHDLGNPGGYLKAAVDFALDRDDYGPDLRQWL
TH_0940|M.thermoresistible__bu      ALLIEEGHPVHAVVHRGTRHDLGNPGGYLKAAVDFALERDDYGPDLREWL
MSMEG_5471|M.smegmatis_MC2_155      ALLIEEDHPVHVVVHRGARHDLGNPGGYLKAAVDFALERDDYGPELRQWL
Mflv_1897|M.gilvum_PYR-GCK          ALLIEEGHPVHVVVHRGSRHDLGNPGGYLKAAVDFALERDDYGPELRRWL
Mvan_4833|M.vanbaalenii_PYR-1       ALLIQEGHPVHVVIHRGSRHDLGNPGGYLKAAVDFALERDDYGPELRRWL
MAB_1086|M.abscessus_ATCC_1997      ALLIDEGHPVHVVVHRGSRHDLGNPGGYLKAAVDFALDRDDYGPGLREWL
                                    **** *.****.*:*:*:*******************:****** **.**

MMAR_4521|M.marinum_M               VARLGLTEQ------
MUL_4693|M.ulcerans_Agy99           VARLGLTEQ------
Mb1020|M.bovis_AF2122/97            VARLGLTEQ------
Rv0993|M.tuberculosis_H37Rv         VARLGLTEQ------
MLBr_00182|M.leprae_Br4923          VERLGLIEQ------
MAV_1102|M.avium_104                VARLGLSEQ------
TH_0940|M.thermoresistible__bu      LERLGLT--------
MSMEG_5471|M.smegmatis_MC2_155      VERLGLAEK------
Mflv_1897|M.gilvum_PYR-GCK          VERLGLPAGTEG---
Mvan_4833|M.vanbaalenii_PYR-1       VERLGLAPATSGQ--
MAB_1086|M.abscessus_ATCC_1997      VERLGRESSVLPESE
                                    : ***