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SIPHTAVVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVAAEAAEAGAERLVIVTSEGKDGVVAHFVQD LVLEGTLEARGKKTMLEKVRRAPALIKVESVVQAEPLGLGHAVSCVESVLAADEDAISVLLPDDLVLPTG VLETMSKVRAKRGGSVLCAIEVPGDKISAYGVFDVETVPDAANPNVLRVKGMVEKPRPEDAPSHFAAAGR YVLDRAIFDALRRVPRGTGGEIQLTDAIALLIEEDHPVHVVVHRGARHDLGNPGGYLKAAVDFALERDDY GPELRQWLVERLGLAEK*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_5471 | galU | - | 100% (298) | UTP-glucose-1-phosphate uridylyltransferase |
M. smegmatis MC2 155 | MSMEG_0384 | rfbA | 2e-09 | 22.92% (253) | glucose-1-phosphate thymidylyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1020 | galU | 1e-140 | 83.06% (301) | UTP--glucose-1-phosphate uridylyltransferase GalU |
M. gilvum PYR-GCK | Mflv_1897 | - | 1e-152 | 90.85% (295) | nucleotidyl transferase |
M. tuberculosis H37Rv | Rv0993 | galU | 1e-140 | 82.72% (301) | UTP--glucose-1-phosphate uridylyltransferase GalU |
M. leprae Br4923 | MLBr_00182 | galU | 1e-144 | 85.57% (298) | putative UTP-glucose-1-phosphate uridylyltransferase |
M. abscessus ATCC 19977 | MAB_1086 | - | 1e-145 | 87.07% (294) | putative UTP-glucose-1-phosphate uridylyltransferase (GalU) |
M. marinum M | MMAR_4521 | galU | 1e-143 | 85.38% (301) | UTP--glucose-1-phosphate uridylyltransferase GalU |
M. avium 104 | MAV_1102 | - | 1e-140 | 83.89% (298) | GalU protein |
M. thermoresistible (build 8) | TH_0940 | galU | 1e-149 | 88.40% (293) | PROBABLE UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE GALU |
M. ulcerans Agy99 | MUL_4693 | galU | 1e-144 | 85.71% (301) | UTP--glucose-1-phosphate uridylyltransferase GalU |
M. vanbaalenii PYR-1 | Mvan_4833 | - | 1e-151 | 90.20% (296) | nucleotidyl transferase |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_4521|M.marinum_M ----MSQEVAIPFTAIVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA MUL_4693|M.ulcerans_Agy99 ----MSQEVAIPFTAIVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA Mb1020|M.bovis_AF2122/97 ---MSRPEVLTPFTAIVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA Rv0993|M.tuberculosis_H37Rv ---MSRPEVLTPFTAIVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA MLBr_00182|M.leprae_Br4923 MSLLLSAQVPIPFTAIVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA MAV_1102|M.avium_104 --------MVVPRTAIVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA MSMEG_5471|M.smegmatis_MC2_155 ---MS-----IPHTAVVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA TH_0940|M.thermoresistible__bu ---MSESRAPVPRTAVVPAAGLGTRFLPVTKTVPKELLPVVDTPGIELVA Mflv_1897|M.gilvum_PYR-GCK ---MNRPEVPVPRTAVVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA Mvan_4833|M.vanbaalenii_PYR-1 ---MNRAEVPIPRTAVVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA MAB_1086|M.abscessus_ATCC_1997 ---MTGPDVLIPRTAVVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA * **:************.********************* MMAR_4521|M.marinum_M AEAAAAGAERLVIVTSEGKDGVVAHFVEDLVLEGTLEARGKTAMLAKVRR MUL_4693|M.ulcerans_Agy99 AEAAAAGAERLVIVTSEGKDGVVAHFVEDLVLEGTLEARGKTAMLAKVRR Mb1020|M.bovis_AF2122/97 AEAAAAGAERLVIVTSEGKDGVVAHFVEDLVLEGTLEARGKIAMLAKVRR Rv0993|M.tuberculosis_H37Rv AEAAAAGAERLVIVTSEGKDGVVAHFVEDLVLEGTLEARGKIAMLAKVRR MLBr_00182|M.leprae_Br4923 AEAAAAGAERLVIVTSEGKDGVVAHFVQDLVLEGTLLARGNKAMLAKVRR MAV_1102|M.avium_104 AEAAEAGAERLVIVTSEGKDGVVAHFVEDLVLESTLEERGKTAMLDKVRR MSMEG_5471|M.smegmatis_MC2_155 AEAAEAGAERLVIVTSEGKDGVVAHFVQDLVLEGTLEARGKKTMLEKVRR TH_0940|M.thermoresistible__bu EEAAEAGAQRLIIITSEGKDSVVAHFVQDLVLEGVLEARGKKTMLEKVRR Mflv_1897|M.gilvum_PYR-GCK AEAAEAGAERLIIITSEGKDGVVAHFVEDLVLEGTLEARGKKTMLEKVRR Mvan_4833|M.vanbaalenii_PYR-1 AEAAEAGAERLIIVTSEGKDGVVAHFVEDLVLEGTLEARGKKTMLEKVRR MAB_1086|M.abscessus_ATCC_1997 EEAAEAGAERLVIVTSEGKDGVVAHFVEDLVLEGTLEARGKHAMLEKVRK *** ***:**:*:******.******:*****..* **: :** ***: MMAR_4521|M.marinum_M APALIKVESVVQAEPLGLGHAISCVEPTLSDDEDAVSVLLPDDLVLPTGV MUL_4693|M.ulcerans_Agy99 APALIKVESVVQAEPLGLGHAISCVEPTLSDDEDAVSVLLPDDLVLPTGV Mb1020|M.bovis_AF2122/97 APALIKVESVVQAEPLGLGHAIGCVEPTLSPDEDAVAVLLPDDLVLPTGV Rv0993|M.tuberculosis_H37Rv APALIKVESVVQAEPLGLGHAIGCVEPTLSPDEDAVAVLLPDDLVLPTGV MLBr_00182|M.leprae_Br4923 APELIKVESVVQAEPLGLGHAIGCAEPTLAPDEDAVSVLLPDDLVLPTGV MAV_1102|M.avium_104 APRLIKVESVVQSEPLGLGHAIGCVEPRLADDEDAVAVLLPDDLVLPTGV MSMEG_5471|M.smegmatis_MC2_155 APALIKVESVVQAEPLGLGHAVSCVESVLAADEDAISVLLPDDLVLPTGV TH_0940|M.thermoresistible__bu APELIRVESVIQQEPLGLGHAVSCVESSLEPDEDAIAVLLPDDLVLPTGI Mflv_1897|M.gilvum_PYR-GCK APALIKVESVVQAEPLGLGHAVGCVEASLAPDEDAIAVLLPDDLVLPTGV Mvan_4833|M.vanbaalenii_PYR-1 APALIKVESVVQAEPLGLGHAISCVEASLAPDEDAIAVLLPDDLVLPTGV MAB_1086|M.abscessus_ATCC_1997 APALIKVQSVVQAEPLGLGHAVGCVESVLDDDEDAVAVLLPDDLVWPRGV ** **:*:**:* ********:.*.*. * ****::******** * *: MMAR_4521|M.marinum_M LETMSKVRARLGGTVLCAIEVSPDEISAYGVFDVEPVPGGEWAANPDVLK MUL_4693|M.ulcerans_Agy99 LETMSKVRARLGGTVLCAIEVSPDEISAYGVFDVEPVPGGEWAANPNVLK Mb1020|M.bovis_AF2122/97 LETMSKVRASRGGTVLCAIEVAREEISAYGVFDVEPVPDGDYTDDPNVLK Rv0993|M.tuberculosis_H37Rv LETMSKVRASRGGTVLCAIEVAREEISAYGVFDVEPVPDGDYTDDPNVLK MLBr_00182|M.leprae_Br4923 LETMSKVRASRGGTVLCAIEVASEEISSYGVFDVEPVPGG---DNPNVLK MAV_1102|M.avium_104 LGTMSKVRAHYGGTVLCAIEVTPEEISAYGVFDVEPVPDD----DPDVLR MSMEG_5471|M.smegmatis_MC2_155 LETMSKVRAKRGGSVLCAIEVPGDKISAYGVFDVETVPDAA---NPNVLR TH_0940|M.thermoresistible__bu LETMSRVRAKRGGSVLCAIEVPGDEISAYGVFDVEPVPDST---NPDVLR Mflv_1897|M.gilvum_PYR-GCK LETMAKVRAKRGGSVLCAIEVDREDISAYGVFDVETVPDAA---NPNVLR Mvan_4833|M.vanbaalenii_PYR-1 LETMSKVRAKRGGSVLCAIEVDREDISAYGVIDVEPLPDAN---NPNVLK MAB_1086|M.abscessus_ATCC_1997 LETMAKVRAKRGGSVLCAIEVPPHEISSYGAFDVEIVPDAA---NPNVLR * **::*** **:******* ..**:**.:*** :*. :*:**: MMAR_4521|M.marinum_M VKGMVEKPKTQDAPSMFAAAGRYVLDRAIFDALRRIERGAGGEVQLTDAI MUL_4693|M.ulcerans_Agy99 VKGMVEKPKTQDAPSMFAAAGRYVLDRAIFDALRRIERGAGGEVQLTDAI Mb1020|M.bovis_AF2122/97 VRGMVEKPKAETAPSRYAAAGRYVLDRAIFDALRRIDRGAGGEVQLTDAI Rv0993|M.tuberculosis_H37Rv VRGMVEKPKAETAPSRYAAAGRYVLDRAIFDALRRIDQGAGGEVQLTDAI MLBr_00182|M.leprae_Br4923 VIGMVEKPKAEDAPSTFAAAGRYVLDRAIFDALRRVSRGTGGEVQITDAI MAV_1102|M.avium_104 VKGMVEKPKAEDAPSMFAAAGRYVLDRAIFDALRRIDRGAGGEVQLTDGI MSMEG_5471|M.smegmatis_MC2_155 VKGMVEKPRPEDAPSHFAAAGRYVLDRAIFDALRRVPRGTGGEIQLTDAI TH_0940|M.thermoresistible__bu VKGMVEKPKPEDAPSPYAAAGRYVLDRAIFDALRRVPRGAGGEIQLTDAI Mflv_1897|M.gilvum_PYR-GCK VKGMVEKPKAEDAPSLFAAAGRYILDRAIFDALKRIPRGAGGELQLTDAI Mvan_4833|M.vanbaalenii_PYR-1 VKGMVEKPKPEDAPSLYAAAGRYVLDRAIFDALRRIPRGAGGELQLTDAI MAB_1086|M.abscessus_ATCC_1997 VKGMVEKPKTEEAPSNYAAAGRYLLDRAIFDALKRIPRGAGGELQLTDAI * ******:.: *** :******:*********:*: :*:***:*:**.* MMAR_4521|M.marinum_M ALLIAEGHPVHVVVHRGSRHDLGNPGGYLKAAVDFALDRDDYGPDLRRWL MUL_4693|M.ulcerans_Agy99 ALLIAEGHPVHVVVHRGSRHDLGNPGGYLKAAVDFALDRDDYGPDLRRWL Mb1020|M.bovis_AF2122/97 ALLIAEGHPVHVVVHQGSRHDLGNPGGYLKAAVDFALDRDDYGPDLRRWL Rv0993|M.tuberculosis_H37Rv ALLIAEGHPVHVVVHQGSRHDLGNPGGYLKAAVDFALDRDDYGPDLRRWL MLBr_00182|M.leprae_Br4923 ALLIKEGHPVHVVVHRGSRHDLGNPGGYLKAAVDFALDRDDYGPDLRRWL MAV_1102|M.avium_104 ALLISEGHPVHVVVHRGSRHDLGNPGGYLKAAVDFALDRDDYGPDLRQWL MSMEG_5471|M.smegmatis_MC2_155 ALLIEEDHPVHVVVHRGARHDLGNPGGYLKAAVDFALERDDYGPELRQWL TH_0940|M.thermoresistible__bu ALLIEEGHPVHAVVHRGTRHDLGNPGGYLKAAVDFALERDDYGPDLREWL Mflv_1897|M.gilvum_PYR-GCK ALLIEEGHPVHVVVHRGSRHDLGNPGGYLKAAVDFALERDDYGPELRRWL Mvan_4833|M.vanbaalenii_PYR-1 ALLIQEGHPVHVVIHRGSRHDLGNPGGYLKAAVDFALERDDYGPELRRWL MAB_1086|M.abscessus_ATCC_1997 ALLIDEGHPVHVVVHRGSRHDLGNPGGYLKAAVDFALDRDDYGPGLREWL **** *.****.*:*:*:*******************:****** **.** MMAR_4521|M.marinum_M VARLGLTEQ------ MUL_4693|M.ulcerans_Agy99 VARLGLTEQ------ Mb1020|M.bovis_AF2122/97 VARLGLTEQ------ Rv0993|M.tuberculosis_H37Rv VARLGLTEQ------ MLBr_00182|M.leprae_Br4923 VERLGLIEQ------ MAV_1102|M.avium_104 VARLGLSEQ------ MSMEG_5471|M.smegmatis_MC2_155 VERLGLAEK------ TH_0940|M.thermoresistible__bu LERLGLT-------- Mflv_1897|M.gilvum_PYR-GCK VERLGLPAGTEG--- Mvan_4833|M.vanbaalenii_PYR-1 VERLGLAPATSGQ-- MAB_1086|M.abscessus_ATCC_1997 VERLGRESSVLPESE : ***