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M. smegmatis MC2 155 MSMEG_5471 (galU)

annotation: UTP-glucose-1-phosphate uridylyltransferase
coordinates: 5553543 - 5554439
length: 298

SIPHTAVVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVAAEAAEAGAERLVIVTSEGKDGVVAHFVQD
LVLEGTLEARGKKTMLEKVRRAPALIKVESVVQAEPLGLGHAVSCVESVLAADEDAISVLLPDDLVLPTG
VLETMSKVRAKRGGSVLCAIEVPGDKISAYGVFDVETVPDAANPNVLRVKGMVEKPRPEDAPSHFAAAGR
YVLDRAIFDALRRVPRGTGGEIQLTDAIALLIEEDHPVHVVVHRGARHDLGNPGGYLKAAVDFALERDDY
GPELRQWLVERLGLAEK*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_5471galU-100% (298)UTP-glucose-1-phosphate uridylyltransferase
M. smegmatis MC2 155MSMEG_0384rfbA2e-0922.92% (253) glucose-1-phosphate thymidylyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1020galU1e-14083.06% (301) UTP--glucose-1-phosphate uridylyltransferase GalU
M. gilvum PYR-GCKMflv_1897-1e-15290.85% (295) nucleotidyl transferase
M. tuberculosis H37RvRv0993galU1e-14082.72% (301) UTP--glucose-1-phosphate uridylyltransferase GalU
M. leprae Br4923MLBr_00182galU1e-14485.57% (298) putative UTP-glucose-1-phosphate uridylyltransferase
M. abscessus ATCC 19977MAB_1086-1e-14587.07% (294) putative UTP-glucose-1-phosphate uridylyltransferase (GalU)
M. marinum MMMAR_4521galU1e-14385.38% (301) UTP--glucose-1-phosphate uridylyltransferase GalU
M. avium 104MAV_1102-1e-14083.89% (298) GalU protein
M. thermoresistible (build 8)TH_0940galU1e-14988.40% (293) PROBABLE UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE GALU
M. ulcerans Agy99MUL_4693galU1e-14485.71% (301) UTP--glucose-1-phosphate uridylyltransferase GalU
M. vanbaalenii PYR-1Mvan_4833-1e-15190.20% (296) nucleotidyl transferase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_4521|M.marinum_M               ----MSQEVAIPFTAIVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA
MUL_4693|M.ulcerans_Agy99           ----MSQEVAIPFTAIVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA
Mb1020|M.bovis_AF2122/97            ---MSRPEVLTPFTAIVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA
Rv0993|M.tuberculosis_H37Rv         ---MSRPEVLTPFTAIVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA
MLBr_00182|M.leprae_Br4923          MSLLLSAQVPIPFTAIVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA
MAV_1102|M.avium_104                --------MVVPRTAIVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA
MSMEG_5471|M.smegmatis_MC2_155      ---MS-----IPHTAVVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA
TH_0940|M.thermoresistible__bu      ---MSESRAPVPRTAVVPAAGLGTRFLPVTKTVPKELLPVVDTPGIELVA
Mflv_1897|M.gilvum_PYR-GCK          ---MNRPEVPVPRTAVVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA
Mvan_4833|M.vanbaalenii_PYR-1       ---MNRAEVPIPRTAVVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA
MAB_1086|M.abscessus_ATCC_1997      ---MTGPDVLIPRTAVVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVA
                                               * **:************.*********************

MMAR_4521|M.marinum_M               AEAAAAGAERLVIVTSEGKDGVVAHFVEDLVLEGTLEARGKTAMLAKVRR
MUL_4693|M.ulcerans_Agy99           AEAAAAGAERLVIVTSEGKDGVVAHFVEDLVLEGTLEARGKTAMLAKVRR
Mb1020|M.bovis_AF2122/97            AEAAAAGAERLVIVTSEGKDGVVAHFVEDLVLEGTLEARGKIAMLAKVRR
Rv0993|M.tuberculosis_H37Rv         AEAAAAGAERLVIVTSEGKDGVVAHFVEDLVLEGTLEARGKIAMLAKVRR
MLBr_00182|M.leprae_Br4923          AEAAAAGAERLVIVTSEGKDGVVAHFVQDLVLEGTLLARGNKAMLAKVRR
MAV_1102|M.avium_104                AEAAEAGAERLVIVTSEGKDGVVAHFVEDLVLESTLEERGKTAMLDKVRR
MSMEG_5471|M.smegmatis_MC2_155      AEAAEAGAERLVIVTSEGKDGVVAHFVQDLVLEGTLEARGKKTMLEKVRR
TH_0940|M.thermoresistible__bu      EEAAEAGAQRLIIITSEGKDSVVAHFVQDLVLEGVLEARGKKTMLEKVRR
Mflv_1897|M.gilvum_PYR-GCK          AEAAEAGAERLIIITSEGKDGVVAHFVEDLVLEGTLEARGKKTMLEKVRR
Mvan_4833|M.vanbaalenii_PYR-1       AEAAEAGAERLIIVTSEGKDGVVAHFVEDLVLEGTLEARGKKTMLEKVRR
MAB_1086|M.abscessus_ATCC_1997      EEAAEAGAERLVIVTSEGKDGVVAHFVEDLVLEGTLEARGKHAMLEKVRK
                                     *** ***:**:*:******.******:*****..*  **: :** ***:

MMAR_4521|M.marinum_M               APALIKVESVVQAEPLGLGHAISCVEPTLSDDEDAVSVLLPDDLVLPTGV
MUL_4693|M.ulcerans_Agy99           APALIKVESVVQAEPLGLGHAISCVEPTLSDDEDAVSVLLPDDLVLPTGV
Mb1020|M.bovis_AF2122/97            APALIKVESVVQAEPLGLGHAIGCVEPTLSPDEDAVAVLLPDDLVLPTGV
Rv0993|M.tuberculosis_H37Rv         APALIKVESVVQAEPLGLGHAIGCVEPTLSPDEDAVAVLLPDDLVLPTGV
MLBr_00182|M.leprae_Br4923          APELIKVESVVQAEPLGLGHAIGCAEPTLAPDEDAVSVLLPDDLVLPTGV
MAV_1102|M.avium_104                APRLIKVESVVQSEPLGLGHAIGCVEPRLADDEDAVAVLLPDDLVLPTGV
MSMEG_5471|M.smegmatis_MC2_155      APALIKVESVVQAEPLGLGHAVSCVESVLAADEDAISVLLPDDLVLPTGV
TH_0940|M.thermoresistible__bu      APELIRVESVIQQEPLGLGHAVSCVESSLEPDEDAIAVLLPDDLVLPTGI
Mflv_1897|M.gilvum_PYR-GCK          APALIKVESVVQAEPLGLGHAVGCVEASLAPDEDAIAVLLPDDLVLPTGV
Mvan_4833|M.vanbaalenii_PYR-1       APALIKVESVVQAEPLGLGHAISCVEASLAPDEDAIAVLLPDDLVLPTGV
MAB_1086|M.abscessus_ATCC_1997      APALIKVQSVVQAEPLGLGHAVGCVESVLDDDEDAVAVLLPDDLVWPRGV
                                    ** **:*:**:* ********:.*.*. *  ****::******** * *:

MMAR_4521|M.marinum_M               LETMSKVRARLGGTVLCAIEVSPDEISAYGVFDVEPVPGGEWAANPDVLK
MUL_4693|M.ulcerans_Agy99           LETMSKVRARLGGTVLCAIEVSPDEISAYGVFDVEPVPGGEWAANPNVLK
Mb1020|M.bovis_AF2122/97            LETMSKVRASRGGTVLCAIEVAREEISAYGVFDVEPVPDGDYTDDPNVLK
Rv0993|M.tuberculosis_H37Rv         LETMSKVRASRGGTVLCAIEVAREEISAYGVFDVEPVPDGDYTDDPNVLK
MLBr_00182|M.leprae_Br4923          LETMSKVRASRGGTVLCAIEVASEEISSYGVFDVEPVPGG---DNPNVLK
MAV_1102|M.avium_104                LGTMSKVRAHYGGTVLCAIEVTPEEISAYGVFDVEPVPDD----DPDVLR
MSMEG_5471|M.smegmatis_MC2_155      LETMSKVRAKRGGSVLCAIEVPGDKISAYGVFDVETVPDAA---NPNVLR
TH_0940|M.thermoresistible__bu      LETMSRVRAKRGGSVLCAIEVPGDEISAYGVFDVEPVPDST---NPDVLR
Mflv_1897|M.gilvum_PYR-GCK          LETMAKVRAKRGGSVLCAIEVDREDISAYGVFDVETVPDAA---NPNVLR
Mvan_4833|M.vanbaalenii_PYR-1       LETMSKVRAKRGGSVLCAIEVDREDISAYGVIDVEPLPDAN---NPNVLK
MAB_1086|M.abscessus_ATCC_1997      LETMAKVRAKRGGSVLCAIEVPPHEISSYGAFDVEIVPDAA---NPNVLR
                                    * **::***  **:*******  ..**:**.:*** :*.     :*:**:

MMAR_4521|M.marinum_M               VKGMVEKPKTQDAPSMFAAAGRYVLDRAIFDALRRIERGAGGEVQLTDAI
MUL_4693|M.ulcerans_Agy99           VKGMVEKPKTQDAPSMFAAAGRYVLDRAIFDALRRIERGAGGEVQLTDAI
Mb1020|M.bovis_AF2122/97            VRGMVEKPKAETAPSRYAAAGRYVLDRAIFDALRRIDRGAGGEVQLTDAI
Rv0993|M.tuberculosis_H37Rv         VRGMVEKPKAETAPSRYAAAGRYVLDRAIFDALRRIDQGAGGEVQLTDAI
MLBr_00182|M.leprae_Br4923          VIGMVEKPKAEDAPSTFAAAGRYVLDRAIFDALRRVSRGTGGEVQITDAI
MAV_1102|M.avium_104                VKGMVEKPKAEDAPSMFAAAGRYVLDRAIFDALRRIDRGAGGEVQLTDGI
MSMEG_5471|M.smegmatis_MC2_155      VKGMVEKPRPEDAPSHFAAAGRYVLDRAIFDALRRVPRGTGGEIQLTDAI
TH_0940|M.thermoresistible__bu      VKGMVEKPKPEDAPSPYAAAGRYVLDRAIFDALRRVPRGAGGEIQLTDAI
Mflv_1897|M.gilvum_PYR-GCK          VKGMVEKPKAEDAPSLFAAAGRYILDRAIFDALKRIPRGAGGELQLTDAI
Mvan_4833|M.vanbaalenii_PYR-1       VKGMVEKPKPEDAPSLYAAAGRYVLDRAIFDALRRIPRGAGGELQLTDAI
MAB_1086|M.abscessus_ATCC_1997      VKGMVEKPKTEEAPSNYAAAGRYLLDRAIFDALKRIPRGAGGELQLTDAI
                                    * ******:.: *** :******:*********:*: :*:***:*:**.*

MMAR_4521|M.marinum_M               ALLIAEGHPVHVVVHRGSRHDLGNPGGYLKAAVDFALDRDDYGPDLRRWL
MUL_4693|M.ulcerans_Agy99           ALLIAEGHPVHVVVHRGSRHDLGNPGGYLKAAVDFALDRDDYGPDLRRWL
Mb1020|M.bovis_AF2122/97            ALLIAEGHPVHVVVHQGSRHDLGNPGGYLKAAVDFALDRDDYGPDLRRWL
Rv0993|M.tuberculosis_H37Rv         ALLIAEGHPVHVVVHQGSRHDLGNPGGYLKAAVDFALDRDDYGPDLRRWL
MLBr_00182|M.leprae_Br4923          ALLIKEGHPVHVVVHRGSRHDLGNPGGYLKAAVDFALDRDDYGPDLRRWL
MAV_1102|M.avium_104                ALLISEGHPVHVVVHRGSRHDLGNPGGYLKAAVDFALDRDDYGPDLRQWL
MSMEG_5471|M.smegmatis_MC2_155      ALLIEEDHPVHVVVHRGARHDLGNPGGYLKAAVDFALERDDYGPELRQWL
TH_0940|M.thermoresistible__bu      ALLIEEGHPVHAVVHRGTRHDLGNPGGYLKAAVDFALERDDYGPDLREWL
Mflv_1897|M.gilvum_PYR-GCK          ALLIEEGHPVHVVVHRGSRHDLGNPGGYLKAAVDFALERDDYGPELRRWL
Mvan_4833|M.vanbaalenii_PYR-1       ALLIQEGHPVHVVIHRGSRHDLGNPGGYLKAAVDFALERDDYGPELRRWL
MAB_1086|M.abscessus_ATCC_1997      ALLIDEGHPVHVVVHRGSRHDLGNPGGYLKAAVDFALDRDDYGPGLREWL
                                    **** *.****.*:*:*:*******************:****** **.**

MMAR_4521|M.marinum_M               VARLGLTEQ------
MUL_4693|M.ulcerans_Agy99           VARLGLTEQ------
Mb1020|M.bovis_AF2122/97            VARLGLTEQ------
Rv0993|M.tuberculosis_H37Rv         VARLGLTEQ------
MLBr_00182|M.leprae_Br4923          VERLGLIEQ------
MAV_1102|M.avium_104                VARLGLSEQ------
MSMEG_5471|M.smegmatis_MC2_155      VERLGLAEK------
TH_0940|M.thermoresistible__bu      LERLGLT--------
Mflv_1897|M.gilvum_PYR-GCK          VERLGLPAGTEG---
Mvan_4833|M.vanbaalenii_PYR-1       VERLGLAPATSGQ--
MAB_1086|M.abscessus_ATCC_1997      VERLGRESSVLPESE
                                    : ***