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M. thermoresistible (build 8) TH_0876 ()

annotation: PROBABLE SHORT-CHAIN TYPE OXIDOREDUCTASE
coordinates: 1778838 - 1779485
length: 216

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0876-100% (216)PROBABLE SHORT-CHAIN TYPE OXIDOREDUCTASE
M. thermoresistible (build 8)TH_0508-4e-2031.00% (200) short chain dehydrogenase
M. thermoresistible (build 8)TH_3268-8e-1734.31% (204) PUTATIVE short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0494c-1e-9581.60% (212) putative short-chain type oxidoreductase
M. gilvum PYR-GCKMflv_0088-9e-8775.49% (204) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37RvRv0484c-1e-9581.60% (212) short-chain type oxidoreductase
M. leprae Br4923MLBr_01094-2e-1234.04% (141) short chain alcohol dehydrogenase
M. abscessus ATCC 19977MAB_4060-7e-9478.10% (210) putative short chain dehydrogenase/reductase
M. marinum MMMAR_0810-4e-9784.62% (208) short-chain type oxidoreductase
M. avium 104MAV_4667-3e-9481.16% (207) oxidoreductase
M. smegmatis MC2 155MSMEG_0930-2e-9585.64% (202) serine 3-dehydrogenase
M. ulcerans Agy99MUL_4554-2e-9684.13% (208) short-chain type oxidoreductase
M. vanbaalenii PYR-1Mvan_0825-1e-9078.40% (213) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0088|M.gilvum_PYR-GCK          MTTPSDARRVAVVTGASAGIGEAIARTLAAQGFHVICVARREGPIKALAA
Mvan_0825|M.vanbaalenii_PYR-1       MTTPTDARRVAVVTGASAGIGEATARTLAAQGFHVICVARREAPIQALAA
TH_0876|M.thermoresistible__bu      -------------------------------------VARRAELVEALAA
MSMEG_0930|M.smegmatis_MC2_155      MSTPHSDRPVAVVTGASAGIGAATAKTLASLGFHVICAARRADRIDALAK
Mb0494c|M.bovis_AF2122/97           MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALAN
Rv0484c|M.tuberculosis_H37Rv        MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALAN
MMAR_0810|M.marinum_M               MTTTDAGNRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALTD
MUL_4554|M.ulcerans_Agy99           MTTTDAGNRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALTD
MAV_4667|M.avium_104                MVGTGRNERVAVVTGASSGIGEATARTLAAQGFHVVAVARRAKRIHALAN
MAB_4060|M.abscessus_ATCC_1997      MTNPTFDGRVAVVTGASSGIGAATAKSLAALGFHVVVAARREDRVKSLAG
MLBr_01094|M.leprae_Br4923          --MEGFAGKVAVVTGAGSGIGQALAIELARSGAKLAISDVDGEGLAQTEG
                                                                                :     

Mflv_0088|M.gilvum_PYR-GCK          EIDGTAIVA-----DVTDPTAVAALAGRLDRVDVLVNNAGGARGLESISD
Mvan_0825|M.vanbaalenii_PYR-1       EIDGTAIVA-----DVTDPTAVAALAGRLDRVDVLVNNAGGARGLESVAD
TH_0876|M.thermoresistible__bu      EISGTASVT-----DVTDRAAVEALADQLDRVDVLVNNAGGAKGLEPVAE
MSMEG_0930|M.smegmatis_MC2_155      EIDGTAVVA-----DVTDDESVNALAAQLDRVDVLVNNAGGAKGLAPVSD
Mb0494c|M.bovis_AF2122/97           QIGGTAIVA-----DVTDDAAVEALARALSRVDVLVNNAGGAKGLQFVAD
Rv0484c|M.tuberculosis_H37Rv        QIGGTAIVA-----DVTDDAAVEALARALSRVDVLVNNAGGAKGLQFVAD
MMAR_0810|M.marinum_M               QIGGTPIVA-----DVTDGAAVAALADGLSRVDVLVNNAGGAKGLEPVAD
MUL_4554|M.ulcerans_Agy99           QIGGTPIVA-----DVTDGAAVAALADGLSRVDVLVNNAGGAKELEPVAD
MAV_4667|M.avium_104                EIGGTAIVA-----DVTDDAAVAALASKLSRVDVLVNNAGGARGLEPVAE
MAB_4060|M.abscessus_ATCC_1997      EIGGTAFVL-----DVTDADSVAALTQSLDRVDVLVNNAGGAWGLEPVLE
MLBr_01094|M.leprae_Br4923          QLKAIGASARTDRLDVTEREAFLTYADVVHENFGKVNQIYNNAGIAFTGD
                                    :: .          ***:  :. : :  : .    **:  .   :    :

Mflv_0088|M.gilvum_PYR-GCK          ADVENWR---WMWEANVMGTLHVTRALLPKLIDSGDGLIVTITSIAAVEI
Mvan_0825|M.vanbaalenii_PYR-1       ADVEHWR---WMWEANVLGTLHVTRALLPKLIGSGDGLIVTVTSIAAVEI
TH_0876|M.thermoresistible__bu      ADLDHWR---WMWETNVLGTLHVTRALLPKLIASGDGLIVTVTSIAAFEI
MSMEG_0930|M.smegmatis_MC2_155      ADLDHWR---WMWETNVLGTLRVTRALLPKLIDSGDGLIVTVTSIAAFET
Mb0494c|M.bovis_AF2122/97           ADLEHWR---WMWDTNVLGTLRVTRALLPKLIDSGDGLIVTVTSIAALEV
Rv0484c|M.tuberculosis_H37Rv        ADLEHWR---WMWDTNVLGTLRVTRALLPKLIDSGDGLIVTVTSIAAIEV
MMAR_0810|M.marinum_M               ADLEHWR---WMWETNVLGTLRVTRALLPKLIASGDGLIVTVTSIAALEI
MUL_4554|M.ulcerans_Agy99           ADLEHWR---WMWETNVLGTLRVTRALLPKLIASGDGLIVTVTSIAALEI
MAV_4667|M.avium_104                ADLEHWR---WMWETNVIGTLRVTRALLPKLVDSGDGLIVTVTSVAALEV
MAB_4060|M.abscessus_ATCC_1997      ADLEHWR---WMWETNVVGTLQVTRALLPKLIDSGDGLIVTVTSIAALDV
MLBr_01094|M.leprae_Br4923          VEVSHFKDIERVMDVDYWGVVNGTKAFLPYLISSGDGHVINISSVFGLFS
                                    .::.:::    : :.:  *.:. *:*:** *: **** ::.::*: ..  

Mflv_0088|M.gilvum_PYR-GCK          YDNGGGYTSAKHAQGVLHRTLRS--ELLGKPVRLTEVAPGMVKTDFSLNR
Mvan_0825|M.vanbaalenii_PYR-1       YDNGAGYTSAKHAQGVLHRTLRS--ELLGKPVRLTEVAPGMVKTEFSLNR
TH_0876|M.thermoresistible__bu      YDGGAGYTAAKHAQSALHRTLRG--ELLGKPVRLTEIQPGMVETEFSLVR
MSMEG_0930|M.smegmatis_MC2_155      YDGGAGYTSAKHAQGALHRTLRG--ELLGKPVRLTEIAPGAVETEFSLVR
Mb0494c|M.bovis_AF2122/97           YDGGAGYTAAKHAQGALHRTLRG--ELLGKPVRLTEIAPGAVETEFSLVR
Rv0484c|M.tuberculosis_H37Rv        YDGGAGYTAAKHAQGALHRTLRG--ELLGKPVRLTEIAPGAVETEFSLVR
MMAR_0810|M.marinum_M               YDGGAGYTAAKHAQGALHRTLRG--ELLGLPVRLTEIAPGAVETEFSLVR
MUL_4554|M.ulcerans_Agy99           YDGGAGYTAAKHAQGALHRTLRG--ELLGLPVRLTEIAPGAVETEFSLVR
MAV_4667|M.avium_104                YDGGAGYTAAKHGQGALHRTLRG--ELLGKPVRLTEIAPGAVETEFSLVR
MAB_4060|M.abscessus_ATCC_1997      YDGGSGYTSAKHAQAALHRTLRG--ELLGKPVRLTEVAPGAVETEFSVVR
MLBr_01094|M.leprae_Br4923          VPGQAAYNSAKFAVRGFTEALREEMALAGRPVNVTTVYPGGIKTAIARNA
                                      . ..*.:**..   : .:**    * * **.:* : ** ::* ::   

Mflv_0088|M.gilvum_PYR-GCK          FDGDAERAEKVYEGVTPLVAEDIAEVVGFVASRPSHVDLDLIVVRPRDQV
Mvan_0825|M.vanbaalenii_PYR-1       FDGDAERADKVYQGVTPLVAEDIAEVIGFVASRPSHVDLDLIVVRPRDQV
TH_0876|M.thermoresistible__bu      FDGDREKADAVYQGLTPLVAEDIAEVIGFAASRPPHVNLDQIVIRPRDQA
MSMEG_0930|M.smegmatis_MC2_155      FDGDRERADNVYKGITPLVAEDIAEVIGFVASRPSHVNLDQIVIRPRDQA
Mb0494c|M.bovis_AF2122/97           FDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA
Rv0484c|M.tuberculosis_H37Rv        FDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA
MMAR_0810|M.marinum_M               FDGDEQRADAVYSGMTPLVAADIAEVIGFVASRPPHVNLDQIIIRPRDQA
MUL_4554|M.ulcerans_Agy99           FDGDEQRADAVYSGMTPLVAADIAEVIGFVASRPPHVNLDQIIIRPRDQA
MAV_4667|M.avium_104                FDGDQQRADAVYTGITPLVAADVAEVIGFVASRPAHVNLDLIVMKPRDQA
MAB_4060|M.abscessus_ATCC_1997      FDGDQDRADAVYRGITPLVAEDVAEIIAFVASRPPHVNLDQIVVKPRDQA
MLBr_01094|M.leprae_Br4923          TAAEGLDVSKIASRFDTWVAHTSPQHAARIILKAVRKKKARVLVGPDAKV
                                      .:   .. :   . . **   .:  .    :. : .   ::: *  :.

Mflv_0088|M.gilvum_PYR-GCK          SGASGSRFHRQS-----------------
Mvan_0825|M.vanbaalenii_PYR-1       SGAAGSRFNRST-----------------
TH_0876|M.thermoresistible__bu      S--ATRKFTRPAGE---------------
MSMEG_0930|M.smegmatis_MC2_155      P--NGR-FNRRT-----------------
Mb0494c|M.bovis_AF2122/97           S--ASRRATHPVR----------------
Rv0484c|M.tuberculosis_H37Rv        S--ASRRATHPVR----------------
MMAR_0810|M.marinum_M               S--ATRRANHQV-----------------
MUL_4554|M.ulcerans_Agy99           S--ATRRANHQV-----------------
MAV_4667|M.avium_104                S--ASRFNRRG------------------
MAB_4060|M.abscessus_ATCC_1997      S--STRRATRQ------------------
MLBr_01094|M.leprae_Br4923          ANVVVRFSGGAGYQRLFAQVASRLILNQR
                                    .