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MTTPSDARRVAVVTGASAGIGEAIARTLAAQGFHVICVARREGPIKALAAEIDGTAIVADVTDPTAVAAL AGRLDRVDVLVNNAGGARGLESISDADVENWRWMWEANVMGTLHVTRALLPKLIDSGDGLIVTITSIAAV EIYDNGGGYTSAKHAQGVLHRTLRSELLGKPVRLTEVAPGMVKTDFSLNRFDGDAERAEKVYEGVTPLVA EDIAEVVGFVASRPSHVDLDLIVVRPRDQVSGASGSRFHRQS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0088 | - | - | 100% (252) | short-chain dehydrogenase/reductase SDR |
| M. gilvum PYR-GCK | Mflv_3370 | - | 2e-22 | 36.22% (185) | short-chain dehydrogenase/reductase SDR |
| M. gilvum PYR-GCK | Mflv_0138 | - | 5e-22 | 36.87% (198) | short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0494c | - | 1e-102 | 74.49% (243) | putative short-chain type oxidoreductase |
| M. tuberculosis H37Rv | Rv0484c | - | 1e-102 | 74.49% (243) | short-chain type oxidoreductase |
| M. leprae Br4923 | MLBr_01094 | - | 2e-18 | 33.17% (199) | short chain alcohol dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4060 | - | 1e-97 | 72.20% (241) | putative short chain dehydrogenase/reductase |
| M. marinum M | MMAR_0810 | - | 1e-100 | 75.10% (241) | short-chain type oxidoreductase |
| M. avium 104 | MAV_4667 | - | 1e-103 | 75.72% (243) | oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_0930 | - | 1e-104 | 75.00% (252) | serine 3-dehydrogenase |
| M. thermoresistible (build 8) | TH_0876 | - | 9e-87 | 75.49% (204) | PROBABLE SHORT-CHAIN TYPE OXIDOREDUCTASE |
| M. ulcerans Agy99 | MUL_4554 | - | 2e-99 | 74.69% (241) | short-chain type oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_0825 | - | 1e-132 | 92.46% (252) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0088|M.gilvum_PYR-GCK MTTPSDARRVAVVTGASAGIGEAIARTLAAQGFHVICVARREGPIKALAA
Mvan_0825|M.vanbaalenii_PYR-1 MTTPTDARRVAVVTGASAGIGEATARTLAAQGFHVICVARREAPIQALAA
MSMEG_0930|M.smegmatis_MC2_155 MSTPHSDRPVAVVTGASAGIGAATAKTLASLGFHVICAARRADRIDALAK
TH_0876|M.thermoresistible__bu -------------------------------------VARRAELVEALAA
Mb0494c|M.bovis_AF2122/97 MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALAN
Rv0484c|M.tuberculosis_H37Rv MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALAN
MMAR_0810|M.marinum_M MTTTDAGNRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALTD
MUL_4554|M.ulcerans_Agy99 MTTTDAGNRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALTD
MAV_4667|M.avium_104 MVGTGRNERVAVVTGASSGIGEATARTLAAQGFHVVAVARRAKRIHALAN
MAB_4060|M.abscessus_ATCC_1997 MTNPTFDGRVAVVTGASSGIGAATAKSLAALGFHVVVAARREDRVKSLAG
MLBr_01094|M.leprae_Br4923 --MEGFAGKVAVVTGAGSGIGQALAIELARSGAKLAISDVDGEGLAQTEG
:
Mflv_0088|M.gilvum_PYR-GCK EIDGTAIVA-----DVTDPTAVAALAGRLDRVDVLVNNAGGARGLESISD
Mvan_0825|M.vanbaalenii_PYR-1 EIDGTAIVA-----DVTDPTAVAALAGRLDRVDVLVNNAGGARGLESVAD
MSMEG_0930|M.smegmatis_MC2_155 EIDGTAVVA-----DVTDDESVNALAAQLDRVDVLVNNAGGAKGLAPVSD
TH_0876|M.thermoresistible__bu EISGTASVT-----DVTDRAAVEALADQLDRVDVLVNNAGGAKGLEPVAE
Mb0494c|M.bovis_AF2122/97 QIGGTAIVA-----DVTDDAAVEALARALSRVDVLVNNAGGAKGLQFVAD
Rv0484c|M.tuberculosis_H37Rv QIGGTAIVA-----DVTDDAAVEALARALSRVDVLVNNAGGAKGLQFVAD
MMAR_0810|M.marinum_M QIGGTPIVA-----DVTDGAAVAALADGLSRVDVLVNNAGGAKGLEPVAD
MUL_4554|M.ulcerans_Agy99 QIGGTPIVA-----DVTDGAAVAALADGLSRVDVLVNNAGGAKELEPVAD
MAV_4667|M.avium_104 EIGGTAIVA-----DVTDDAAVAALASKLSRVDVLVNNAGGARGLEPVAE
MAB_4060|M.abscessus_ATCC_1997 EIGGTAFVL-----DVTDADSVAALTQSLDRVDVLVNNAGGAWGLEPVLE
MLBr_01094|M.leprae_Br4923 QLKAIGASARTDRLDVTEREAFLTYADVVHENFGKVNQIYNNAGIAFTGD
:: . ***: :. : : : . **: . : :
Mflv_0088|M.gilvum_PYR-GCK ADVENWR---WMWEANVMGTLHVTRALLPKLIDSGDGLIVTITSIAAVEI
Mvan_0825|M.vanbaalenii_PYR-1 ADVEHWR---WMWEANVLGTLHVTRALLPKLIGSGDGLIVTVTSIAAVEI
MSMEG_0930|M.smegmatis_MC2_155 ADLDHWR---WMWETNVLGTLRVTRALLPKLIDSGDGLIVTVTSIAAFET
TH_0876|M.thermoresistible__bu ADLDHWR---WMWETNVLGTLHVTRALLPKLIASGDGLIVTVTSIAAFEI
Mb0494c|M.bovis_AF2122/97 ADLEHWR---WMWDTNVLGTLRVTRALLPKLIDSGDGLIVTVTSIAALEV
Rv0484c|M.tuberculosis_H37Rv ADLEHWR---WMWDTNVLGTLRVTRALLPKLIDSGDGLIVTVTSIAAIEV
MMAR_0810|M.marinum_M ADLEHWR---WMWETNVLGTLRVTRALLPKLIASGDGLIVTVTSIAALEI
MUL_4554|M.ulcerans_Agy99 ADLEHWR---WMWETNVLGTLRVTRALLPKLIASGDGLIVTVTSIAALEI
MAV_4667|M.avium_104 ADLEHWR---WMWETNVIGTLRVTRALLPKLVDSGDGLIVTVTSVAALEV
MAB_4060|M.abscessus_ATCC_1997 ADLEHWR---WMWETNVVGTLQVTRALLPKLIDSGDGLIVTVTSIAALDV
MLBr_01094|M.leprae_Br4923 VEVSHFKDIERVMDVDYWGVVNGTKAFLPYLISSGDGHVINISSVFGLFS
.::.::: : :.: *.:. *:*:** *: **** ::.::*: ..
Mflv_0088|M.gilvum_PYR-GCK YDNGGGYTSAKHAQGVLHRTLRS--ELLGKPVRLTEVAPGMVKTDFSLNR
Mvan_0825|M.vanbaalenii_PYR-1 YDNGAGYTSAKHAQGVLHRTLRS--ELLGKPVRLTEVAPGMVKTEFSLNR
MSMEG_0930|M.smegmatis_MC2_155 YDGGAGYTSAKHAQGALHRTLRG--ELLGKPVRLTEIAPGAVETEFSLVR
TH_0876|M.thermoresistible__bu YDGGAGYTAAKHAQSALHRTLRG--ELLGKPVRLTEIQPGMVETEFSLVR
Mb0494c|M.bovis_AF2122/97 YDGGAGYTAAKHAQGALHRTLRG--ELLGKPVRLTEIAPGAVETEFSLVR
Rv0484c|M.tuberculosis_H37Rv YDGGAGYTAAKHAQGALHRTLRG--ELLGKPVRLTEIAPGAVETEFSLVR
MMAR_0810|M.marinum_M YDGGAGYTAAKHAQGALHRTLRG--ELLGLPVRLTEIAPGAVETEFSLVR
MUL_4554|M.ulcerans_Agy99 YDGGAGYTAAKHAQGALHRTLRG--ELLGLPVRLTEIAPGAVETEFSLVR
MAV_4667|M.avium_104 YDGGAGYTAAKHGQGALHRTLRG--ELLGKPVRLTEIAPGAVETEFSLVR
MAB_4060|M.abscessus_ATCC_1997 YDGGSGYTSAKHAQAALHRTLRG--ELLGKPVRLTEVAPGAVETEFSVVR
MLBr_01094|M.leprae_Br4923 VPGQAAYNSAKFAVRGFTEALREEMALAGRPVNVTTVYPGGIKTAIARNA
. ..*.:**.. : .:** * * **.:* : ** ::* ::
Mflv_0088|M.gilvum_PYR-GCK FDGDAERAEKVYEGVTPLVAEDIAEVVGFVASRPSHVDLDLIVVRPRDQV
Mvan_0825|M.vanbaalenii_PYR-1 FDGDAERADKVYQGVTPLVAEDIAEVIGFVASRPSHVDLDLIVVRPRDQV
MSMEG_0930|M.smegmatis_MC2_155 FDGDRERADNVYKGITPLVAEDIAEVIGFVASRPSHVNLDQIVIRPRDQA
TH_0876|M.thermoresistible__bu FDGDREKADAVYQGLTPLVAEDIAEVIGFAASRPPHVNLDQIVIRPRDQA
Mb0494c|M.bovis_AF2122/97 FDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA
Rv0484c|M.tuberculosis_H37Rv FDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA
MMAR_0810|M.marinum_M FDGDEQRADAVYSGMTPLVAADIAEVIGFVASRPPHVNLDQIIIRPRDQA
MUL_4554|M.ulcerans_Agy99 FDGDEQRADAVYSGMTPLVAADIAEVIGFVASRPPHVNLDQIIIRPRDQA
MAV_4667|M.avium_104 FDGDQQRADAVYTGITPLVAADVAEVIGFVASRPAHVNLDLIVMKPRDQA
MAB_4060|M.abscessus_ATCC_1997 FDGDQDRADAVYRGITPLVAEDVAEIIAFVASRPPHVNLDQIVVKPRDQA
MLBr_01094|M.leprae_Br4923 TAAEGLDVSKIASRFDTWVAHTSPQHAARIILKAVRKKKARVLVGPDAKV
.: .. : . . ** .: . :. : . ::: * :.
Mflv_0088|M.gilvum_PYR-GCK SGASGSRFHRQS-----------------
Mvan_0825|M.vanbaalenii_PYR-1 SGAAGSRFNRST-----------------
MSMEG_0930|M.smegmatis_MC2_155 P--NGR-FNRRT-----------------
TH_0876|M.thermoresistible__bu S--ATRKFTRPAGE---------------
Mb0494c|M.bovis_AF2122/97 S--ASRRATHPVR----------------
Rv0484c|M.tuberculosis_H37Rv S--ASRRATHPVR----------------
MMAR_0810|M.marinum_M S--ATRRANHQV-----------------
MUL_4554|M.ulcerans_Agy99 S--ATRRANHQV-----------------
MAV_4667|M.avium_104 S--ASRFNRRG------------------
MAB_4060|M.abscessus_ATCC_1997 S--STRRATRQ------------------
MLBr_01094|M.leprae_Br4923 ANVVVRFSGGAGYQRLFAQVASRLILNQR
.