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M. thermoresistible (build 8) TH_0850 (nrdB)

annotation: PROBABLE RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (BETA CHAIN) NRDB (RIBONUCLEOTIDE REDUCTASE SMALL CHAIN)
coordinates: 1743281 - 1744159
length: 293

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0850nrdB-100% (293)PROBABLE RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (BETA CHAIN) NRDB (RIBONUCLEOTIDE REDUCTASE SMALL CHAIN)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0238nrdB1e-14078.84% (293) ribonucleotide-diphosphate reductase subunit beta
M. gilvum PYR-GCKMflv_3061-1e-15386.99% (292) ribonucleotide-diphosphate reductase subunit beta
M. tuberculosis H37RvRv0233nrdB1e-14078.84% (293) ribonucleotide-diphosphate reductase subunit beta
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4007c-1e-14380.89% (293) ribonucleotide-diphosphate reductase subunit beta
M. marinum M-----
M. avium 104MAV_4937-1e-14179.66% (290) ribonucleotide-diphosphate reductase subunit beta
M. smegmatis MC2 155MSMEG_0358-1e-14180.41% (291) ribonucleotide-diphosphate reductase subunit beta
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_3466-1e-15790.07% (292) ribonucleotide-diphosphate reductase subunit beta

CLUSTAL 2.0.9 multiple sequence alignment


Mb0238|M.bovis_AF2122/97            MTRTRSGSLAAGGLNWASLPLKLFAGGNAKFWDPADIDFTRDRADWEKLS
Rv0233|M.tuberculosis_H37Rv         MTRTRSGSLAAGGLNWASLPLKLFAGGNAKFWHPADIDFTRDRADWEKLS
MAV_4937|M.avium_104                MNRTRSASMVQGGLNWDSLPLKLFAGGNAKFWNPADIDFSRDRADWERLT
MAB_4007c|M.abscessus_ATCC_199      MTRTQYGSLRAGGLNWDSMPLKLFAGGNAKFWDPAGIDFSRDRADWESLT
MSMEG_0358|M.smegmatis_MC2_155      MTRTHFDSIRAGGLNWSSLPLKLFAGGNAKFWDPADIDFSRDRADWEALT
Mflv_3061|M.gilvum_PYR-GCK          MNRTRSDSLAAGGLNWDSLPLRLFAGGNAKFWDPADIDFSRDRADWESLS
Mvan_3466|M.vanbaalenii_PYR-1       MARTRSDSLAAGGLNWDSLPLRLFAGGNAKFWDPADIDFSRDRADWESLT
TH_0850|M.thermoresistible__bu      --------------------LKLFTKGNAKFWNPADIDFSRDREDWESLT
                                                        *:**: ******.**.***:*** *** *:

Mb0238|M.bovis_AF2122/97            DDERDYATRLCTQFIAGEEAVTEDIQPFMSAMRAEGRLADEMYLTQFAFE
Rv0233|M.tuberculosis_H37Rv         DDERDYATRLCTQFIAGEEAVTEDIQPFMSAMRAEGRLADEMYLTQFAFE
MAV_4937|M.avium_104                DDERSYATRLCAEFIAGEESVTQDIQPFMAAMRAEGRLGDEMYLTQFAFE
MAB_4007c|M.abscessus_ATCC_199      ERERDYATRLCAQFIAGEESVTQDIQPFMSAMRAEGRLGDEMYLTQFAFE
MSMEG_0358|M.smegmatis_MC2_155      EREREYATRLCAEFIAGEEAVTKDIQPFMSAMRAEGRLGDEMYLTQFAFE
Mflv_3061|M.gilvum_PYR-GCK          TMERDWATRLCAEFIAGEEAVTQDIQPFMAAMRAEGRLGDEMYLTQFAFE
Mvan_3466|M.vanbaalenii_PYR-1       DLERDWATRLCAEFIAGEEAVTQDIQPFMAAMRAEGRLGDEMYLTQFAFE
TH_0850|M.thermoresistible__bu      QLERDWATRLCAQFIAGEEAVTQDIQPFMAAMRAEGRLGDEMYLTQFAFE
                                      **.:*****::******:**:******:********.***********

Mb0238|M.bovis_AF2122/97            EAKHTQVFRMWLDAVGISEDLHRYLDDLPAYRQIFYAELPECLNALSADP
Rv0233|M.tuberculosis_H37Rv         EAKHTQVFRMWLDAVGISEDLHRYLDDLPAYRQIFYAELPECLNALSADP
MAV_4937|M.avium_104                EAKHVQVFRMWLDAVGVTDDLHHFLDDVPSYRTIFYEELPDCLNALTIDP
MAB_4007c|M.abscessus_ATCC_199      EAKHTQVFRLWLDAVGVSEDLHGYLDDLPAYREIFFDRLPDALGMLAADP
MSMEG_0358|M.smegmatis_MC2_155      EAKHTQVFRMWLDAVGVTDDLHSLIEEVPAYVQIFCEELPAALEALTSDP
Mflv_3061|M.gilvum_PYR-GCK          EAKHTQVFRMWLDAVGITEDLQGYLDDLPAYRQMFYEELPASLDALATDP
Mvan_3466|M.vanbaalenii_PYR-1       EAKHTQVFRMWLDAVGITEDLQGYLDELPAYCQMFYEELPASLDALATDP
TH_0850|M.thermoresistible__bu      EAKHTQVFRMWLDAVGMTDDLHHYLDELPAYRQMFYDELPSSLEVLATDP
                                    ****.****:******:::**:  ::::*:*  :*  .** .*  *: **

Mb0238|M.bovis_AF2122/97            SPAAQVRASVTYNHIVEGMLALTGYYAWHKICVERAILPGMQELVRRIGD
Rv0233|M.tuberculosis_H37Rv         SPAAQVRASVTYNHIVEGMLALTGYYAWHKICVERAILPGMQELVRRIGD
MAV_4937|M.avium_104                SPAAQVRASVTYNHMVEGMLALTGYFGWHKICVERGILPGMQELVRRIGD
MAB_4007c|M.abscessus_ATCC_199      SPAAQVRASVTYNHVVEGMLALTGYFAWHKICVDRGILPGMQELVHRIGD
MSMEG_0358|M.smegmatis_MC2_155      SPAAQVRASVVYNHVVEGMLALTGYYAWHRICVDRGILPGMQELVRRIGD
Mflv_3061|M.gilvum_PYR-GCK          SPQAQVRASVTYNHVIEGMMALTGYYAWHRICVDRHILPGMQELVRRIGD
Mvan_3466|M.vanbaalenii_PYR-1       SPAAQVRASVTYNHVIEGMMALTGYYAWHRICVDRGILPGMQELVRRIGD
TH_0850|M.thermoresistible__bu      SPAAQVRASVTYNHVIEGMMALTGYYAWQRICVDRGILPGMQELVRRIGD
                                    ** *******.***::***:*****:.*::***:* *********:****

Mb0238|M.bovis_AF2122/97            DERRHMAWGTFTCRRHVAADDANWTVFETRMNELIPLALRLIEEGFALYG
Rv0233|M.tuberculosis_H37Rv         DERRHMAWGTFTCRRHVAADDANWTVFETRMNELIPLALRLIEEGFALYG
MAV_4937|M.avium_104                DERRHMAWGTFTCRRHVAADDANWGVFETRMNELMPLGLRLIEEGFALY-
MAB_4007c|M.abscessus_ATCC_199      DERRHMAWGTFTCRRHVAADDANWSVFEARMNELIPIALRLTEEGFELYG
MSMEG_0358|M.smegmatis_MC2_155      DERRHMAWGTFTCRRHVAADDANWAVFETHMNELIPVALRLTQEGFALYG
Mflv_3061|M.gilvum_PYR-GCK          DERRHMAWGTFTCRRHVAADDANWTVFEDRMNELIPLALQNTDDAFALY-
Mvan_3466|M.vanbaalenii_PYR-1       DERRHMAWGTFTCRRHVAADDANWAVFETRMNELIPLALRNTEDGFALY-
TH_0850|M.thermoresistible__bu      DERRHMAWGTFTCRRHVAADDANWNVFEERMNELIPLVLKNTEDGFAVY-
                                    ************************ *** :****:*: *:  ::.* :* 

Mb0238|M.bovis_AF2122/97            DQPPFDLSKDDFLQYSTDKGMRRFGTISNARGRPVAEIDVDYSPAQLEDT
Rv0233|M.tuberculosis_H37Rv         DQPPFDLSKDDFLQYSTDKGMRRFGTISNARGRPVAEIDVDYSPAQLEDT
MAV_4937|M.avium_104                DPMPFDLSVDEFMAYASDKGMRRFGTIASARGRPLAEIDLDYTPVQLEDT
MAB_4007c|M.abscessus_ATCC_199      DDTPFGLSLDEFMQYSADKGMRRFGTISSARGRPLAEIDLDYSPLQLEDT
MSMEG_0358|M.smegmatis_MC2_155      DDIPFGLEEGEFLQYSSDRGMRRFGTISSARGRPLAEIDVDYTPLQLEDT
Mflv_3061|M.gilvum_PYR-GCK          DEIPFGLTIEEFQQYAADKGMRRFGTISSARGRPLAEIDVDYTPLHLEDS
Mvan_3466|M.vanbaalenii_PYR-1       DEVPFGLTMEEFQQYAADKGMRRFGTISSARGRPLAEIDVDYSPLHLEDT
TH_0850|M.thermoresistible__bu      DEVPFGLTMDEFQQYATDKGMRRFGTISSARGRPLSEIDVDYSPLTLEDT
                                    *  **.*   :*  *::*:********:.*****::***:**:*  ***:

Mb0238|M.bovis_AF2122/97            FADEDRRTLAAASA------
Rv0233|M.tuberculosis_H37Rv         FADEDRRTLAAASA------
MAV_4937|M.avium_104                FADEDARALAAV--------
MAB_4007c|M.abscessus_ATCC_199      FAAEDRQALAATA-------
MSMEG_0358|M.smegmatis_MC2_155      FADEDERALTAVKAAAAAAN
Mflv_3061|M.gilvum_PYR-GCK          FADEDRKALAASA-------
Mvan_3466|M.vanbaalenii_PYR-1       FADEDRKSLAASA-------
TH_0850|M.thermoresistible__bu      FADEDEKAMAASA-------
                                    ** ** ::::*