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M. vanbaalenii PYR-1 Mvan_3466 (-)

annotation: ribonucleotide-diphosphate reductase subunit beta
coordinates: 3680304 - 3681242
length: 312

ARTRSDSLAAGGLNWDSLPLRLFAGGNAKFWDPADIDFSRDRADWESLTDLERDWATRLCAEFIAGEEAV
TQDIQPFMAAMRAEGRLGDEMYLTQFAFEEAKHTQVFRMWLDAVGITEDLQGYLDELPAYCQMFYEELPA
SLDALATDPSPAAQVRASVTYNHVIEGMMALTGYYAWHRICVDRGILPGMQELVRRIGDDERRHMAWGTF
TCRRHVAADDANWAVFETRMNELIPLALRNTEDGFALYDEVPFGLTMEEFQQYAADKGMRRFGTISSARG
RPLAEIDVDYSPLHLEDTFADEDRKSLAASA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_3466--100% (312)ribonucleotide-diphosphate reductase subunit beta

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0238nrdB1e-15482.43% (313) ribonucleotide-diphosphate reductase subunit beta
M. gilvum PYR-GCKMflv_3061-1e-17594.23% (312) ribonucleotide-diphosphate reductase subunit beta
M. tuberculosis H37RvRv0233nrdB1e-15482.11% (313) ribonucleotide-diphosphate reductase subunit beta
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4007c-1e-15682.43% (313) ribonucleotide-diphosphate reductase subunit beta
M. marinum M-----
M. avium 104MAV_4937-1e-15280.97% (310) ribonucleotide-diphosphate reductase subunit beta
M. smegmatis MC2 155MSMEG_0358-1e-15582.96% (311) ribonucleotide-diphosphate reductase subunit beta
M. thermoresistible (build 8)TH_0850nrdB1e-15790.07% (292) PROBABLE RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (BETA CHAIN)
M. ulcerans Agy99-----

CLUSTAL 2.0.9 multiple sequence alignment


Mb0238|M.bovis_AF2122/97            MTRTRSGSLAAGGLNWASLPLKLFAGGNAKFWDPADIDFTRDRADWEKLS
Rv0233|M.tuberculosis_H37Rv         MTRTRSGSLAAGGLNWASLPLKLFAGGNAKFWHPADIDFTRDRADWEKLS
MAV_4937|M.avium_104                MNRTRSASMVQGGLNWDSLPLKLFAGGNAKFWNPADIDFSRDRADWERLT
MAB_4007c|M.abscessus_ATCC_199      MTRTQYGSLRAGGLNWDSMPLKLFAGGNAKFWDPAGIDFSRDRADWESLT
MSMEG_0358|M.smegmatis_MC2_155      MTRTHFDSIRAGGLNWSSLPLKLFAGGNAKFWDPADIDFSRDRADWEALT
Mvan_3466|M.vanbaalenii_PYR-1       MARTRSDSLAAGGLNWDSLPLRLFAGGNAKFWDPADIDFSRDRADWESLT
Mflv_3061|M.gilvum_PYR-GCK          MNRTRSDSLAAGGLNWDSLPLRLFAGGNAKFWDPADIDFSRDRADWESLS
TH_0850|M.thermoresistible__bu      --------------------LKLFTKGNAKFWNPADIDFSRDREDWESLT
                                                        *:**: ******.**.***:*** *** *:

Mb0238|M.bovis_AF2122/97            DDERDYATRLCTQFIAGEEAVTEDIQPFMSAMRAEGRLADEMYLTQFAFE
Rv0233|M.tuberculosis_H37Rv         DDERDYATRLCTQFIAGEEAVTEDIQPFMSAMRAEGRLADEMYLTQFAFE
MAV_4937|M.avium_104                DDERSYATRLCAEFIAGEESVTQDIQPFMAAMRAEGRLGDEMYLTQFAFE
MAB_4007c|M.abscessus_ATCC_199      ERERDYATRLCAQFIAGEESVTQDIQPFMSAMRAEGRLGDEMYLTQFAFE
MSMEG_0358|M.smegmatis_MC2_155      EREREYATRLCAEFIAGEEAVTKDIQPFMSAMRAEGRLGDEMYLTQFAFE
Mvan_3466|M.vanbaalenii_PYR-1       DLERDWATRLCAEFIAGEEAVTQDIQPFMAAMRAEGRLGDEMYLTQFAFE
Mflv_3061|M.gilvum_PYR-GCK          TMERDWATRLCAEFIAGEEAVTQDIQPFMAAMRAEGRLGDEMYLTQFAFE
TH_0850|M.thermoresistible__bu      QLERDWATRLCAQFIAGEEAVTQDIQPFMAAMRAEGRLGDEMYLTQFAFE
                                      **.:*****::******:**:******:********.***********

Mb0238|M.bovis_AF2122/97            EAKHTQVFRMWLDAVGISEDLHRYLDDLPAYRQIFYAELPECLNALSADP
Rv0233|M.tuberculosis_H37Rv         EAKHTQVFRMWLDAVGISEDLHRYLDDLPAYRQIFYAELPECLNALSADP
MAV_4937|M.avium_104                EAKHVQVFRMWLDAVGVTDDLHHFLDDVPSYRTIFYEELPDCLNALTIDP
MAB_4007c|M.abscessus_ATCC_199      EAKHTQVFRLWLDAVGVSEDLHGYLDDLPAYREIFFDRLPDALGMLAADP
MSMEG_0358|M.smegmatis_MC2_155      EAKHTQVFRMWLDAVGVTDDLHSLIEEVPAYVQIFCEELPAALEALTSDP
Mvan_3466|M.vanbaalenii_PYR-1       EAKHTQVFRMWLDAVGITEDLQGYLDELPAYCQMFYEELPASLDALATDP
Mflv_3061|M.gilvum_PYR-GCK          EAKHTQVFRMWLDAVGITEDLQGYLDDLPAYRQMFYEELPASLDALATDP
TH_0850|M.thermoresistible__bu      EAKHTQVFRMWLDAVGMTDDLHHYLDELPAYRQMFYDELPSSLEVLATDP
                                    ****.****:******:::**:  ::::*:*  :*  .** .*  *: **

Mb0238|M.bovis_AF2122/97            SPAAQVRASVTYNHIVEGMLALTGYYAWHKICVERAILPGMQELVRRIGD
Rv0233|M.tuberculosis_H37Rv         SPAAQVRASVTYNHIVEGMLALTGYYAWHKICVERAILPGMQELVRRIGD
MAV_4937|M.avium_104                SPAAQVRASVTYNHMVEGMLALTGYFGWHKICVERGILPGMQELVRRIGD
MAB_4007c|M.abscessus_ATCC_199      SPAAQVRASVTYNHVVEGMLALTGYFAWHKICVDRGILPGMQELVHRIGD
MSMEG_0358|M.smegmatis_MC2_155      SPAAQVRASVVYNHVVEGMLALTGYYAWHRICVDRGILPGMQELVRRIGD
Mvan_3466|M.vanbaalenii_PYR-1       SPAAQVRASVTYNHVIEGMMALTGYYAWHRICVDRGILPGMQELVRRIGD
Mflv_3061|M.gilvum_PYR-GCK          SPQAQVRASVTYNHVIEGMMALTGYYAWHRICVDRHILPGMQELVRRIGD
TH_0850|M.thermoresistible__bu      SPAAQVRASVTYNHVIEGMMALTGYYAWQRICVDRGILPGMQELVRRIGD
                                    ** *******.***::***:*****:.*::***:* *********:****

Mb0238|M.bovis_AF2122/97            DERRHMAWGTFTCRRHVAADDANWTVFETRMNELIPLALRLIEEGFALYG
Rv0233|M.tuberculosis_H37Rv         DERRHMAWGTFTCRRHVAADDANWTVFETRMNELIPLALRLIEEGFALYG
MAV_4937|M.avium_104                DERRHMAWGTFTCRRHVAADDANWGVFETRMNELMPLGLRLIEEGFALY-
MAB_4007c|M.abscessus_ATCC_199      DERRHMAWGTFTCRRHVAADDANWSVFEARMNELIPIALRLTEEGFELYG
MSMEG_0358|M.smegmatis_MC2_155      DERRHMAWGTFTCRRHVAADDANWAVFETHMNELIPVALRLTQEGFALYG
Mvan_3466|M.vanbaalenii_PYR-1       DERRHMAWGTFTCRRHVAADDANWAVFETRMNELIPLALRNTEDGFALY-
Mflv_3061|M.gilvum_PYR-GCK          DERRHMAWGTFTCRRHVAADDANWTVFEDRMNELIPLALQNTDDAFALY-
TH_0850|M.thermoresistible__bu      DERRHMAWGTFTCRRHVAADDANWNVFEERMNELIPLVLKNTEDGFAVY-
                                    ************************ *** :****:*: *:  ::.* :* 

Mb0238|M.bovis_AF2122/97            DQPPFDLSKDDFLQYSTDKGMRRFGTISNARGRPVAEIDVDYSPAQLEDT
Rv0233|M.tuberculosis_H37Rv         DQPPFDLSKDDFLQYSTDKGMRRFGTISNARGRPVAEIDVDYSPAQLEDT
MAV_4937|M.avium_104                DPMPFDLSVDEFMAYASDKGMRRFGTIASARGRPLAEIDLDYTPVQLEDT
MAB_4007c|M.abscessus_ATCC_199      DDTPFGLSLDEFMQYSADKGMRRFGTISSARGRPLAEIDLDYSPLQLEDT
MSMEG_0358|M.smegmatis_MC2_155      DDIPFGLEEGEFLQYSSDRGMRRFGTISSARGRPLAEIDVDYTPLQLEDT
Mvan_3466|M.vanbaalenii_PYR-1       DEVPFGLTMEEFQQYAADKGMRRFGTISSARGRPLAEIDVDYSPLHLEDT
Mflv_3061|M.gilvum_PYR-GCK          DEIPFGLTIEEFQQYAADKGMRRFGTISSARGRPLAEIDVDYTPLHLEDS
TH_0850|M.thermoresistible__bu      DEVPFGLTMDEFQQYATDKGMRRFGTISSARGRPLSEIDVDYSPLTLEDT
                                    *  **.*   :*  *::*:********:.*****::***:**:*  ***:

Mb0238|M.bovis_AF2122/97            FADEDRRTLAAASA------
Rv0233|M.tuberculosis_H37Rv         FADEDRRTLAAASA------
MAV_4937|M.avium_104                FADEDARALAAV--------
MAB_4007c|M.abscessus_ATCC_199      FAAEDRQALAATA-------
MSMEG_0358|M.smegmatis_MC2_155      FADEDERALTAVKAAAAAAN
Mvan_3466|M.vanbaalenii_PYR-1       FADEDRKSLAASA-------
Mflv_3061|M.gilvum_PYR-GCK          FADEDRKALAASA-------
TH_0850|M.thermoresistible__bu      FADEDEKAMAASA-------
                                    ** ** ::::*