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MTRTRSGSLAAGGLNWASLPLKLFAGGNAKFWHPADIDFTRDRADWEKLSDDERDYATRLCTQFIAGEEA VTEDIQPFMSAMRAEGRLADEMYLTQFAFEEAKHTQVFRMWLDAVGISEDLHRYLDDLPAYRQIFYAELP ECLNALSADPSPAAQVRASVTYNHIVEGMLALTGYYAWHKICVERAILPGMQELVRRIGDDERRHMAWGT FTCRRHVAADDANWTVFETRMNELIPLALRLIEEGFALYGDQPPFDLSKDDFLQYSTDKGMRRFGTISNA RGRPVAEIDVDYSPAQLEDTFADEDRRTLAAASA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0233 | nrdB | - | 100% (314) | ribonucleotide-diphosphate reductase subunit beta |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0238 | nrdB | 0.0 | 99.68% (314) | ribonucleotide-diphosphate reductase subunit beta |
| M. gilvum PYR-GCK | Mflv_3061 | - | 1e-151 | 80.83% (313) | ribonucleotide-diphosphate reductase subunit beta |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4007c | - | 1e-156 | 82.75% (313) | ribonucleotide-diphosphate reductase subunit beta |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_4937 | - | 1e-156 | 82.64% (311) | ribonucleotide-diphosphate reductase subunit beta |
| M. smegmatis MC2 155 | MSMEG_0358 | - | 1e-152 | 80.25% (314) | ribonucleotide-diphosphate reductase subunit beta |
| M. thermoresistible (build 8) | TH_0850 | nrdB | 1e-140 | 78.84% (293) | PROBABLE RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (BETA CHAIN) |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3466 | - | 1e-153 | 82.11% (313) | ribonucleotide-diphosphate reductase subunit beta |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0233|M.tuberculosis_H37Rv MTRTRSGSLAAGGLNWASLPLKLFAGGNAKFWHPADIDFTRDRADWEKLS
Mb0238|M.bovis_AF2122/97 MTRTRSGSLAAGGLNWASLPLKLFAGGNAKFWDPADIDFTRDRADWEKLS
MAV_4937|M.avium_104 MNRTRSASMVQGGLNWDSLPLKLFAGGNAKFWNPADIDFSRDRADWERLT
MAB_4007c|M.abscessus_ATCC_199 MTRTQYGSLRAGGLNWDSMPLKLFAGGNAKFWDPAGIDFSRDRADWESLT
MSMEG_0358|M.smegmatis_MC2_155 MTRTHFDSIRAGGLNWSSLPLKLFAGGNAKFWDPADIDFSRDRADWEALT
Mflv_3061|M.gilvum_PYR-GCK MNRTRSDSLAAGGLNWDSLPLRLFAGGNAKFWDPADIDFSRDRADWESLS
Mvan_3466|M.vanbaalenii_PYR-1 MARTRSDSLAAGGLNWDSLPLRLFAGGNAKFWDPADIDFSRDRADWESLT
TH_0850|M.thermoresistible__bu --------------------LKLFTKGNAKFWNPADIDFSRDREDWESLT
*:**: ******.**.***:*** *** *:
Rv0233|M.tuberculosis_H37Rv DDERDYATRLCTQFIAGEEAVTEDIQPFMSAMRAEGRLADEMYLTQFAFE
Mb0238|M.bovis_AF2122/97 DDERDYATRLCTQFIAGEEAVTEDIQPFMSAMRAEGRLADEMYLTQFAFE
MAV_4937|M.avium_104 DDERSYATRLCAEFIAGEESVTQDIQPFMAAMRAEGRLGDEMYLTQFAFE
MAB_4007c|M.abscessus_ATCC_199 ERERDYATRLCAQFIAGEESVTQDIQPFMSAMRAEGRLGDEMYLTQFAFE
MSMEG_0358|M.smegmatis_MC2_155 EREREYATRLCAEFIAGEEAVTKDIQPFMSAMRAEGRLGDEMYLTQFAFE
Mflv_3061|M.gilvum_PYR-GCK TMERDWATRLCAEFIAGEEAVTQDIQPFMAAMRAEGRLGDEMYLTQFAFE
Mvan_3466|M.vanbaalenii_PYR-1 DLERDWATRLCAEFIAGEEAVTQDIQPFMAAMRAEGRLGDEMYLTQFAFE
TH_0850|M.thermoresistible__bu QLERDWATRLCAQFIAGEEAVTQDIQPFMAAMRAEGRLGDEMYLTQFAFE
**.:*****::******:**:******:********.***********
Rv0233|M.tuberculosis_H37Rv EAKHTQVFRMWLDAVGISEDLHRYLDDLPAYRQIFYAELPECLNALSADP
Mb0238|M.bovis_AF2122/97 EAKHTQVFRMWLDAVGISEDLHRYLDDLPAYRQIFYAELPECLNALSADP
MAV_4937|M.avium_104 EAKHVQVFRMWLDAVGVTDDLHHFLDDVPSYRTIFYEELPDCLNALTIDP
MAB_4007c|M.abscessus_ATCC_199 EAKHTQVFRLWLDAVGVSEDLHGYLDDLPAYREIFFDRLPDALGMLAADP
MSMEG_0358|M.smegmatis_MC2_155 EAKHTQVFRMWLDAVGVTDDLHSLIEEVPAYVQIFCEELPAALEALTSDP
Mflv_3061|M.gilvum_PYR-GCK EAKHTQVFRMWLDAVGITEDLQGYLDDLPAYRQMFYEELPASLDALATDP
Mvan_3466|M.vanbaalenii_PYR-1 EAKHTQVFRMWLDAVGITEDLQGYLDELPAYCQMFYEELPASLDALATDP
TH_0850|M.thermoresistible__bu EAKHTQVFRMWLDAVGMTDDLHHYLDELPAYRQMFYDELPSSLEVLATDP
****.****:******:::**: ::::*:* :* .** .* *: **
Rv0233|M.tuberculosis_H37Rv SPAAQVRASVTYNHIVEGMLALTGYYAWHKICVERAILPGMQELVRRIGD
Mb0238|M.bovis_AF2122/97 SPAAQVRASVTYNHIVEGMLALTGYYAWHKICVERAILPGMQELVRRIGD
MAV_4937|M.avium_104 SPAAQVRASVTYNHMVEGMLALTGYFGWHKICVERGILPGMQELVRRIGD
MAB_4007c|M.abscessus_ATCC_199 SPAAQVRASVTYNHVVEGMLALTGYFAWHKICVDRGILPGMQELVHRIGD
MSMEG_0358|M.smegmatis_MC2_155 SPAAQVRASVVYNHVVEGMLALTGYYAWHRICVDRGILPGMQELVRRIGD
Mflv_3061|M.gilvum_PYR-GCK SPQAQVRASVTYNHVIEGMMALTGYYAWHRICVDRHILPGMQELVRRIGD
Mvan_3466|M.vanbaalenii_PYR-1 SPAAQVRASVTYNHVIEGMMALTGYYAWHRICVDRGILPGMQELVRRIGD
TH_0850|M.thermoresistible__bu SPAAQVRASVTYNHVIEGMMALTGYYAWQRICVDRGILPGMQELVRRIGD
** *******.***::***:*****:.*::***:* *********:****
Rv0233|M.tuberculosis_H37Rv DERRHMAWGTFTCRRHVAADDANWTVFETRMNELIPLALRLIEEGFALYG
Mb0238|M.bovis_AF2122/97 DERRHMAWGTFTCRRHVAADDANWTVFETRMNELIPLALRLIEEGFALYG
MAV_4937|M.avium_104 DERRHMAWGTFTCRRHVAADDANWGVFETRMNELMPLGLRLIEEGFALY-
MAB_4007c|M.abscessus_ATCC_199 DERRHMAWGTFTCRRHVAADDANWSVFEARMNELIPIALRLTEEGFELYG
MSMEG_0358|M.smegmatis_MC2_155 DERRHMAWGTFTCRRHVAADDANWAVFETHMNELIPVALRLTQEGFALYG
Mflv_3061|M.gilvum_PYR-GCK DERRHMAWGTFTCRRHVAADDANWTVFEDRMNELIPLALQNTDDAFALY-
Mvan_3466|M.vanbaalenii_PYR-1 DERRHMAWGTFTCRRHVAADDANWAVFETRMNELIPLALRNTEDGFALY-
TH_0850|M.thermoresistible__bu DERRHMAWGTFTCRRHVAADDANWNVFEERMNELIPLVLKNTEDGFAVY-
************************ *** :****:*: *: ::.* :*
Rv0233|M.tuberculosis_H37Rv DQPPFDLSKDDFLQYSTDKGMRRFGTISNARGRPVAEIDVDYSPAQLEDT
Mb0238|M.bovis_AF2122/97 DQPPFDLSKDDFLQYSTDKGMRRFGTISNARGRPVAEIDVDYSPAQLEDT
MAV_4937|M.avium_104 DPMPFDLSVDEFMAYASDKGMRRFGTIASARGRPLAEIDLDYTPVQLEDT
MAB_4007c|M.abscessus_ATCC_199 DDTPFGLSLDEFMQYSADKGMRRFGTISSARGRPLAEIDLDYSPLQLEDT
MSMEG_0358|M.smegmatis_MC2_155 DDIPFGLEEGEFLQYSSDRGMRRFGTISSARGRPLAEIDVDYTPLQLEDT
Mflv_3061|M.gilvum_PYR-GCK DEIPFGLTIEEFQQYAADKGMRRFGTISSARGRPLAEIDVDYTPLHLEDS
Mvan_3466|M.vanbaalenii_PYR-1 DEVPFGLTMEEFQQYAADKGMRRFGTISSARGRPLAEIDVDYSPLHLEDT
TH_0850|M.thermoresistible__bu DEVPFGLTMDEFQQYATDKGMRRFGTISSARGRPLSEIDVDYSPLTLEDT
* **.* :* *::*:********:.*****::***:**:* ***:
Rv0233|M.tuberculosis_H37Rv FADEDRRTLAAASA------
Mb0238|M.bovis_AF2122/97 FADEDRRTLAAASA------
MAV_4937|M.avium_104 FADEDARALAAV--------
MAB_4007c|M.abscessus_ATCC_199 FAAEDRQALAATA-------
MSMEG_0358|M.smegmatis_MC2_155 FADEDERALTAVKAAAAAAN
Mflv_3061|M.gilvum_PYR-GCK FADEDRKALAASA-------
Mvan_3466|M.vanbaalenii_PYR-1 FADEDRKSLAASA-------
TH_0850|M.thermoresistible__bu FADEDEKAMAASA-------
** ** ::::*