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M. thermoresistible (build 8) TH_0755 (-)

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_0755	-	-	100% (190)	drug resistance transporter Bcr/CflA subfamily protein

Closest Orthologs (e-value cutoff: 1e-4)

species	id	gene	e-value	identity (len)	annotation
M. bovis AF2122 / 97	-	-	-	-	-
M. gilvum PYR-GCK	Mflv_2220	-	5e-57	63.43% (175)	Bcr/CflA subfamily drug resistance transporter
M. tuberculosis H37Rv	-	-	-	-	-
M. leprae Br4923	-	-	-	-	-
M. abscessus ATCC 19977	MAB_1395	-	2e-50	60.61% (165)	Bcr/CflA family multidrug resistance transporter
M. marinum M	-	-	-	-	-
M. avium 104	-	-	-	-	-
M. smegmatis MC2 155	MSMEG_5047	-	1e-56	68.12% (160)	drug resistance transporter Bcr/CflA subfamily protein
M. ulcerans Agy99	-	-	-	-	-
M. vanbaalenii PYR-1	Mvan_4475	-	4e-58	65.14% (175)	Bcr/CflA subfamily drug resistance transporter

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2220|M.gilvum_PYR-GCK          MSLINFMAISPDVKLKAQSPESAGPPS-----------RTRMIIVLGLLV
Mvan_4475|M.vanbaalenii_PYR-1       ----------------------MAPPG-----------RTRMILVLGLLV
MSMEG_5047|M.smegmatis_MC2_155      ------------------------MPS-----------RTRMILVLGALI
TH_0755|M.thermoresistible__bu      --------------------------------------------------
MAB_1395|M.abscessus_ATCC_1997      MRALSTEVTSAPGKTTVDDPATDRTPAGSVSPPATRLGRAWLITVLGAMV
                                                                                      

Mflv_2220|M.gilvum_PYR-GCK          ALGPLTIDMYLPALPKIGEELSVSSSVAQLTLTGTLAGLAIGQLVIGPLS
Mvan_4475|M.vanbaalenii_PYR-1       ALGPLTIDMYLPALPKIAEELSVSSSVAQLTLTGTLAGLAIGQLVIGPLS
MSMEG_5047|M.smegmatis_MC2_155      TLGPLTIDMYLPALPKIGEELSVSSSVAQLTLTGTLAGLALGQLVVGSLS
TH_0755|M.thermoresistible__bu      --------------------------------------------------
MAB_1395|M.abscessus_ATCC_1997      ALGPLTIDMYLPALPDIGSDLHVNSTLTQLTLTGTLVGLGLGQLLVGPLS
                                                                                      

Mflv_2220|M.gilvum_PYR-GCK          DSLGRRKPLFAGIVLHMVASLLCMFAPTITVLGIARGLQGMGAAAGMVVA
Mvan_4475|M.vanbaalenii_PYR-1       DSLGRRRPLFAGIVLHMLASLLCLLAPNITVLGVARCLQGMGAAAGMVVA
MSMEG_5047|M.smegmatis_MC2_155      DSLGRRRPLLAGIVLHMAASVLCFLAPNIAVLGIARGLQGMGASAAAVVA
TH_0755|M.thermoresistible__bu      --------------------------------------------------
MAB_1395|M.abscessus_ATCC_1997      DSLGRRLPLIAGAILHIVASLAITIAPNIVVLGVLRAVEGMGAAAAMVVA
                                                                                      

Mflv_2220|M.gilvum_PYR-GCK          IAVVGDLYKDNAAATVMSRLMLVLGVAPVLAPSLGAAVLLHGSWHWVFAA
Mvan_4475|M.vanbaalenii_PYR-1       IAVVGDLYKDNVAATVMSRLMLVLGVAPVLAPSFGAAVLLHGSWHWVFAA
MSMEG_5047|M.smegmatis_MC2_155      IAVVGDLYSGNTAATVMSRLMLVLGVAPVLAPSLGAAVLLKASWHWVFVA
TH_0755|M.thermoresistible__bu      --------------------------------------------------
MAB_1395|M.abscessus_ATCC_1997      MAVVRDLYTDKAAATVISRLTLVIGIAPILAPSLGAAVLVHGSWQNVFAA
                                                                                      

Mflv_2220|M.gilvum_PYR-GCK          LVVVAAALLVMAVLALPETLPVDHRRPLKVRGIAATYLELVRDARFVILV
Mvan_4475|M.vanbaalenii_PYR-1       LVVVAGALLVMSVLALPETLPADHRRPLKARGIALTYLELLRDVRFVILV
MSMEG_5047|M.smegmatis_MC2_155      LVILAGLLLVMAALALPETLPTSHRRPLKVGGIMRTYGRLLHDARFVILV
TH_0755|M.thermoresistible__bu      ----------MSEEPLGEXX------------------------------
MAB_1395|M.abscessus_ATCC_1997      LSCLGVLLLILAVVALPETLPPSARRPLRAGAILRTYRDLLRDKVFVVLV
                                              ::  .* *                                

Mflv_2220|M.gilvum_PYR-GCK          LVAALGMSGLFAYIAGASFVLQGRFGLDQTAFALVFGAGAVALIGTTQCN
Mvan_4475|M.vanbaalenii_PYR-1       FVGALGMSGLFAYIAGASFVLQGRFGLDQTAFALVFGAGAIALIGTTQFN
MSMEG_5047|M.smegmatis_MC2_155      LVAALGMSGLFAYISAAPFVLQGRYGLDQQMFAAVFAAGAVALIGSTQFN
TH_0755|M.thermoresistible__bu      -----------XYISGAAFVLQDGYGLNQQAFALVFGAGAIALIGATQFN
MAB_1395|M.abscessus_ATCC_1997      LVAGLSLSGLFAYISGASFVLQGQYGMNQQVFALAFGAGAIAFVAASQLN
                                                **:.*.****. :*::*  ** .*.***:*::.::* *

Mflv_2220|M.gilvum_PYR-GCK          VILLKRFTPQQIMVWALAASSVFGLVFVALAAAGVGGVFGFVIPVWAILA
Mvan_4475|M.vanbaalenii_PYR-1       VVLLKRFAPQQIMVWALVAASLSGAVFVALAAAHIGGLWGFVIPVWAILA
MSMEG_5047|M.smegmatis_MC2_155      VVLLRRFTPQAITVAALASATVVGAVFVGLTIADVGGLIGFLVPVMAILT
TH_0755|M.thermoresistible__bu      VVLLRRFDPSTIVVTALAVASVLGFVFVGLAVTGVGGLAGFVLPVWGVLG
MAB_1395|M.abscessus_ATCC_1997      VVLLKRFEPQQIVRWCLSLALIPAVVLLVLAGFGIGGLVGFVAPVWTLMA
                                    *:**:** *. *   .*  : : . *:: *:   :**: **: **  :: 

Mflv_2220|M.gilvum_PYR-GCK          AMGLVIPNAPAVALTRHPDAAGTAAALLGAVQFGGGAAIAPVVGVLGNDE
Mvan_4475|M.vanbaalenii_PYR-1       AMGLVIPNAPAVALTRHPDAAGTAAALLGAVQFGMGAAIAPVVGVLGNDE
MSMEG_5047|M.smegmatis_MC2_155      AMGFVIPNAPAVALSRHSEAAGTAAALLGAAQFGIGALVAPLVGALGNGA
TH_0755|M.thermoresistible__bu      AMGFVLPNAPALALSRHPEASGTAAALLGCGQFGLGAVISPLVGVLGNSA
MAB_1395|M.abscessus_ATCC_1997      LMGFVIPNAPALALSRHGEAAGTSAAVLGAAQFGVGAVIAPLVGALGNNA
                                     **:*:*****:**:** :*:**:**:**. *** ** ::*:**.***. 

Mflv_2220|M.gilvum_PYR-GCK          LAMAVVMAAGVIIALGALLVTG-AHRNTEPAR----------VPDEAVAE
Mvan_4475|M.vanbaalenii_PYR-1       LAMAVVMAAGVIVALTALLVTG-VHRNTAPAA----------VPGEAVAE
MSMEG_5047|M.smegmatis_MC2_155      LALSGVMTAGMAIALVALLLVGGSHADDETHDGNEDGPGSDDVVAEAVAE
TH_0755|M.thermoresistible__bu      PAMAAVMTGGVLIALVALLAAG-VRPGAEHRD-----------TADMLVE
MAB_1395|M.abscessus_ATCC_1997      LAVAIVMMIGVVLALAGLAVVR-----------------------NRVAA
                                     *:: **  *: :** .*  .                        : :. 

Mflv_2220|M.gilvum_PYR-GCK          PA
Mvan_4475|M.vanbaalenii_PYR-1       PA
MSMEG_5047|M.smegmatis_MC2_155      PA
TH_0755|M.thermoresistible__bu      HA
MAB_1395|M.abscessus_ATCC_1997      --