For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_0727 | - | - | 100% (646) | acyl-CoA oxidase |
| M. thermoresistible (build 8) | TH_3384 | - | 2e-15 | 24.56% (399) | PUTATIVE acyl-CoA dehydrogenase domain protein |
| M. thermoresistible (build 8) | TH_3736 | - | 3e-14 | 25.17% (449) | PUTATIVE acyl-CoA dehydrogenase domain protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2528c | fadE19 | 6e-15 | 23.94% (376) | acyl-CoA dehydrogenase |
| M. gilvum PYR-GCK | Mflv_2726 | - | 0.0 | 80.47% (645) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv2500c | fadE19 | 6e-15 | 23.94% (376) | acyl-CoA dehydrogenase |
| M. leprae Br4923 | MLBr_00845 | - | 1e-34 | 57.26% (124) | hypothetical protein MLBr_00845 |
| M. abscessus ATCC 19977 | MAB_3588 | - | 0.0 | 57.44% (632) | putative acyl-CoA oxidase |
| M. marinum M | MMAR_3631 | - | 0.0 | 80.03% (641) | acyl-CoA dehydrogenase |
| M. avium 104 | MAV_2078 | - | 0.0 | 81.96% (643) | acyl-CoA oxidase |
| M. smegmatis MC2 155 | MSMEG_4474 | - | 0.0 | 83.49% (642) | acyl-CoA oxidase |
| M. ulcerans Agy99 | MUL_1233 | - | 0.0 | 78.94% (641) | acyl-CoA dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_3808 | - | 0.0 | 82.17% (645) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2726|M.gilvum_PYR-GCK ----------------MTTTAEHLRNSLDGRFRDVKNRVRRELSDDVFRP
Mvan_3808|M.vanbaalenii_PYR-1 MRHHGLRIPRDGYRPDMTTTAEHLRNSLDGRFRDVKNRVRRELSDEVFRP
MSMEG_4474|M.smegmatis_MC2_155 ----------------MTTTAEHLRNALDGRWRDVKNAMRENLSNEVFRP
TH_0727|M.thermoresistible__bu ----------------MTTTAEHLRNALDGRWRDVKNEMRERLSDEVFRP
MMAR_3631|M.marinum_M ------------MAPDMTNTAKHLRDALDGRFRDVKNEMRQQLTLEIFRP
MUL_1233|M.ulcerans_Agy99 ------------MAPDMTNTAKHLRDALDGRFRDVKNAMRQQLTLEIFRP
MAV_2078|M.avium_104 ------------MAPETTSTAEHLRNALDGRWRDVRNRMRETLSEDLFRP
MLBr_00845|M.leprae_Br4923 --------------------------------------------------
MAB_3588|M.abscessus_ATCC_1997 -------METRTAPADPEVLTSNLRVALDGRFGPIRDAAREYLNRADLLP
Mb2528c|M.bovis_AF2122/97 ---------------MTTTTTTISGGILPKEYQDLRDTVADFARTVVAP-
Rv2500c|M.tuberculosis_H37Rv ---------------MTTTTTTISGGILPKEYQDLRDTVADFARTVVAP-
Mflv_2726|M.gilvum_PYR-GCK HYTPNTVIARTKVAEQMKIMAARGAAEDGFKKEHGGNG-DVGAAVTQIEM
Mvan_3808|M.vanbaalenii_PYR-1 HYTPNTVIARTKVAEQLKIMAAQGAAEDGFKKEHGGNG-DVGAAVTQIEM
MSMEG_4474|M.smegmatis_MC2_155 HYTPNTAIARAKVAEQLKIMAAAGAAEDGFRKEHGGNG-NVGAAIAQIEM
TH_0727|M.thermoresistible__bu HFTPNTVIARTKVNEQLRIMAAAGAAEDGFRKEHGGTG-DVGAAITRIEM
MMAR_3631|M.marinum_M HYTPNTVIARAKVAEQMKFMAGAGAAEDSFRKEHGGTG-NVGAAITMIEM
MUL_1233|M.ulcerans_Agy99 HYTPNTVIARAKVAEQMRFMAGAGAAEDSFRKEHGGTG-NVGAAITMIEM
MAV_2078|M.avium_104 HYTPNTVIARTKVAEQMRIMAAFGAAADGFRKEHGGTG-DVGAAITMIEM
MLBr_00845|M.leprae_Br4923 --------------------------------------------------
MAB_3588|M.abscessus_ATCC_1997 DPSLTLEQARARSLRIMRELVPHGLPHAGFRTEHGGTG-DVGAAIVGIEM
Mb2528c|M.bovis_AF2122/97 -VSAKHDAEHSFPYEIVAKMGEMGLFGLPFPEEYGGMGGDYFALSLVLEE
Rv2500c|M.tuberculosis_H37Rv -VSAKHDAEHSFPYEIVAKMGEMGLFGLPFPEEYGGMGGDYFALSLVLEE
Mflv_2726|M.gilvum_PYR-GCK LAMSDLSLMVKAGVQWGLFGGAIENLGTERHHAAYVKKLINLEVLGCFAM
Mvan_3808|M.vanbaalenii_PYR-1 LAMSDLSLMVKAGVQWGLFGGAIENLGTERHHKAYVKKLIDLELLGCFAM
MSMEG_4474|M.smegmatis_MC2_155 LAMSDLSLMVKAGVQWGLFGGAIENLGTERHHQAYVRRIIDLDLLGCFAM
TH_0727|M.thermoresistible__bu LAMSDLSLMVKAGVQWGLFGGAIENLGTERHHRKYVRRIIDCDLLGCFAM
MMAR_3631|M.marinum_M LAMSDLSLMVKAGVQWGLFGGAVENLGTERHHEQYVPKIIDLQLRGCFAM
MUL_1233|M.ulcerans_Agy99 LAMSDLSLMVKAGVQWGLFGGAVENLGTERHHEQYVPKIIDLQLRGCFAM
MAV_2078|M.avium_104 LAMSDLSLMVKAGVQWGLFGGAVENLGTERHHETYVPKIISLELRGCFAM
MLBr_00845|M.leprae_Br4923 --------------------------------------------------
MAB_3588|M.abscessus_ATCC_1997 LGYADLSLMVKAGVQWGLFGGAIENLGTATHHEQYVVPLINLDVLGCFGM
Mb2528c|M.bovis_AF2122/97 LGKVDQSVAITLEAAVGLGAMPIYRFGTEEQKQKWLPDLTSGRALAGFGL
Rv2500c|M.tuberculosis_H37Rv LGKVDQSVAITLEAAVGLGAMPIYRFGTEEQKQKWLPDLTSGRALAGFGL
Mflv_2726|M.gilvum_PYR-GCK TETGHGSDVQSLETTATYDPATQEFVIDSPTPSSRKDYIGGAAETARVAA
Mvan_3808|M.vanbaalenii_PYR-1 TETGHGSDVQSLETTATYDPATEEFVIDSPTRTSRKDYIGGAAETARVAA
MSMEG_4474|M.smegmatis_MC2_155 TETGHGSDVQSIETTATYDPATQEFVIHSPTPTARKDYIGGAAETARVAA
TH_0727|M.thermoresistible__bu TETGHGSNVQALETTATYDPATREFVIHSPTPTSRKDYIGGAAQTARMAA
MMAR_3631|M.marinum_M TETGHGSDVQSLETTATYDADTEEFIIDSPTPTARKDYIGGAAETATIAA
MUL_1233|M.ulcerans_Agy99 TETGHGSDVQSLETTATYDADTEEFIIDPPTPTARKDYIGGAAETATIAA
MAV_2078|M.avium_104 TETGHGSDVQSLETTATYDPATEEFVIDSPTPSARKDYIGGAAETATVAA
MLBr_00845|M.leprae_Br4923 --------------------------------------------------
MAB_3588|M.abscessus_ATCC_1997 TETGHGSNVQALQTVATYDRTTGDFVLNSEGSLARKDYIGGAAEHATVSA
Mb2528c|M.bovis_AF2122/97 TEPGAGSDAGSTRTTARLE--GDEWIINGS-----KQFITNSGTDITSLV
Rv2500c|M.tuberculosis_H37Rv TEPGAGSDAGSTRTTARLE--GDEWIINGS-----KQFITNSGTDITSLV
Mflv_2726|M.gilvum_PYR-GCK VFAQLIT-PDG---VKHGVHCFVVPIRDEQGEDLPGVTTSDCHYKGGLPG
Mvan_3808|M.vanbaalenii_PYR-1 VFAQLIT-PDG---ETHGVHCFVVPIRDDDGNDLPGVTTSDCHYKGGLPG
MSMEG_4474|M.smegmatis_MC2_155 VFAQLIT-PDG---MNHGVHCLVVPIRDDEGNDLPGVTTSDCHYKGGLPG
TH_0727|M.thermoresistible__bu VFAQLIT-HEDGAPVQHGVHCLLVPLRDEDGNDLPGVTTSDNDYKGGLPG
MMAR_3631|M.marinum_M VFAQLIT-QIDGEQANHGVHCFLVPIRDEDGNDLPGVTTSDCHYKGGLPG
MUL_1233|M.ulcerans_Agy99 VFAQLIT-QIDGEQANHGVHCFLVPIRDEDGNDLPGVTTSDCHYKGGLPD
MAV_2078|M.avium_104 VFAQLIT-TEDGKPVNHGVHCLLVPIRDADGNDLPGVTTSDCEYKGGLPG
MLBr_00845|M.leprae_Br4923 --------------------------------------------------
MAB_3588|M.abscessus_ATCC_1997 VFAQLVTGGPGEEATGRGVHCFVVPIRDADGNDLPGITTSDCGYKGGLAG
Mb2528c|M.bovis_AF2122/97 TVTAVTGTTGTAADAKKEISTIIVPSG------TPGFTVEPVYNKVGWNA
Rv2500c|M.tuberculosis_H37Rv TVTAVTGTTGTAADAKKEISTIIVPSG------TPGFTVEPVYNKVGWNA
Mflv_2726|M.gilvum_PYR-GCK VDNGRIQFDEVRIPRENLLNKYADVAEDGTYSSPIENPNRRFFTMLGTLI
Mvan_3808|M.vanbaalenii_PYR-1 VDNGRIQFDQVRVPRENLLNRYADVAADGTYTSPIENPNRRFFTMLGTLI
MSMEG_4474|M.smegmatis_MC2_155 VDNGRIVFDHVRVPRENLLNRYADVSPEGVYSSPIENPGRRFFTMLGTLI
TH_0727|M.thermoresistible__bu VDNGRIMFDHVRVPRENLLNRYGDVSEDGTYTSPIESPGRRFFTMLGTLV
MMAR_3631|M.marinum_M VDNGRITFDHVRIPRVNLLNRYGDVATDGTYSSPIDNPNRRFFTMIGTLI
MUL_1233|M.ulcerans_Agy99 VDNGRITFDHVRIPWVNLLNRYGDVATDGTYSSPIDNPNRRFFTMIGTLI
MAV_2078|M.avium_104 VDNGRIVFDHVRVPRVNLLNKYGDVAPDGTYSSPIENPNRRFFTMLGTLV
MLBr_00845|M.leprae_Br4923 --------------------------------------------------
MAB_3588|M.abscessus_ATCC_1997 VDNGRIVFDNVRVPRANLLNRYADVAEDGTYSSPIENENKRFFTMLGTLI
Mb2528c|M.bovis_AF2122/97 SDTHPLTFADARVPRENLLG------------------------------
Rv2500c|M.tuberculosis_H37Rv SDTHPLTFADARVPRENLLG------------------------------
Mflv_2726|M.gilvum_PYR-GCK RGRVTVGGSAGAAARVALDIATRYALQRRQFEDPDG--GEVLLMDYLVHQ
Mvan_3808|M.vanbaalenii_PYR-1 RGRVTVGGSAGAAARVALDIATRYALQRRQFSDPDG--GEVLLMDYLVHQ
MSMEG_4474|M.smegmatis_MC2_155 RGRVTVGGSAAAAARVALDIATRYALQRTQFSAPDDE-HEVVIMDYLVHQ
TH_0727|M.thermoresistible__bu RGRVTVGGSASAAARVALDIATRYALQRRQFSGPGDDDTEVLIMDYLVHQ
MMAR_3631|M.marinum_M RGRVTVGGSAAAAARVALDIATRYALQRRQFSAPDDDDTEVLIMDYLMHQ
MUL_1233|M.ulcerans_Agy99 RGRVTVGGSAAAAARVALDIATRYALQRRQFSAPDDDDTEVLIMDYLMHQ
MAV_2078|M.avium_104 RGRITVGGSAGAAGRVALDIATRYALQRKQFTTPDGD-SEVLIMDYLVHQ
MLBr_00845|M.leprae_Br4923 --------------------------------------------------
MAB_3588|M.abscessus_ATCC_1997 RGRVSVAATSGAAARKALTIASRYALVRKQFDTPDSD-DEVIIADYLVHQ
Mb2528c|M.bovis_AF2122/97 --------------------------------------------------
Rv2500c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_2726|M.gilvum_PYR-GCK RRLFPLIARSYALQYAQNELVARCHELQTADDPDPEDQRELESRAAGLKA
Mvan_3808|M.vanbaalenii_PYR-1 RRLFPLIARSYALQFAQNELVAKCHELQTADDPDPEEQRELESRAAGLKA
MSMEG_4474|M.smegmatis_MC2_155 RRLLPLIAKSYALQFAQNELVAKCHELQTSDDPDPEEQRELEARAAGLKA
TH_0727|M.thermoresistible__bu RRLFPLIAESYALQFAQNELVAKCHDLQSQDDPDPEEQRELEARAAGLKA
MMAR_3631|M.marinum_M RRLFPLIARSYALQFAQNELVSKCHDLQTTDSPDAEEQRELEARAAGLKA
MUL_1233|M.ulcerans_Agy99 RRLFPLIARSYALQFAQNELVSKCHDLQTTDSPDAEEQRELEARAAGLKA
MAV_2078|M.avium_104 RRLFPLIAKSYALQFAQNELVSKCHDIQSADDPDADEQRELEARAAGLKA
MLBr_00845|M.leprae_Br4923 --------------------------------------------------
MAB_3588|M.abscessus_ATCC_1997 RKLLPLIARSYALAFAQNELTEELHQVQTADEVDADRQRQLESAAAGLKA
Mb2528c|M.bovis_AF2122/97 --------------------------------------------------
Rv2500c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_2726|M.gilvum_PYR-GCK ANTWHATRAIQEAREACGGAGYLAENRLIALKADTDVFTTFEGDNHVLFQ
Mvan_3808|M.vanbaalenii_PYR-1 ANTWHATRAIQEAREACGGAGYMAENRLIALKADTDVFTTFEGDNHVLYQ
MSMEG_4474|M.smegmatis_MC2_155 ANTWHASTAIQEAREACGGAGYLAENRLIALRADTDVFTTFEGDNHVLTQ
TH_0727|M.thermoresistible__bu VGTWHASRAIQESREACGGAGYMGENRLVGLRGDIDVFTTFEGDNTVMLQ
MMAR_3631|M.marinum_M ANTWHASRAIQEAREACGGAGYMAENRLIALRADTDVFTTFEGDNHVLTQ
MUL_1233|M.ulcerans_Agy99 ANTWHASRAIQEAREACGGTGYMAENRLIALRADTDVFTTFEGDNHVLTQ
MAV_2078|M.avium_104 ANTWHATRAIQESREACGGAGYMAENRLIALRGDTDVFTTFEGDNHVLTQ
MLBr_00845|M.leprae_Br4923 ----------------------------MPLR------------------
MAB_3588|M.abscessus_ATCC_1997 MTSWHAQHAITVCREACGGAGYLDANQLTILRRDIDVFTTFEGDNTVLTQ
Mb2528c|M.bovis_AF2122/97 ----------------ARGSGYAN--------------------------
Rv2500c|M.tuberculosis_H37Rv ----------------ARGSGYAN--------------------------
Mflv_2726|M.gilvum_PYR-GCK LVAKELLTAYADDIKGMSPVDWVRFAANFAGERVLKRTAAQTIMQTILDT
Mvan_3808|M.vanbaalenii_PYR-1 LVAKELLTAYADDIKGMSPVEWVRFAASFAGERVLKRTAAQTIMQTVLDT
MSMEG_4474|M.smegmatis_MC2_155 LVAKELLTAYADDIKGMSPVEWVRFAANFAGERVLKRTAAQTIIQTILDT
TH_0727|M.thermoresistible__bu QVAKGLLTAYADDVRSMSPVEWVRFAANTVGTRVLKRTAAQPIIQTILDN
MMAR_3631|M.marinum_M LVAKELLTAYADDIRSMSPVEWVRFAANAVGDRVMKRTAAEAIMQRIVDA
MUL_1233|M.ulcerans_Agy99 LVAKELLTAYADDIRSMSPVEWVRFAANAVGDWVMKRTAAEAITQRIVDA
MAV_2078|M.avium_104 LVAKELLTAYADDIKSMSPVEWVRFAANAVGDRVIKRTAAETIIQTIVDA
MLBr_00845|M.leprae_Br4923 -------------------------PTNAASERVTKRTATETILQRMVGA
MAB_3588|M.abscessus_ATCC_1997 LVAKELLSAYAEDVRGLNAVGWTRFIAGMARDVILERSAARQVIQTILDS
Mb2528c|M.bovis_AF2122/97 ------------------------FLSILDEGRIAIAALATGAAQGCVDE
Rv2500c|M.tuberculosis_H37Rv ------------------------FLSILDEGRIAIAALATGAAQGCVDE
: : : : * :.
Mflv_2726|M.gilvum_PYR-GCK REDNEEEGSLFNRGTQVQMFEDREQYMLSSVARRIQ-SKSKEMGAFDAFN
Mvan_3808|M.vanbaalenii_PYR-1 RQDNEEEGSLFNRGTQVKMFEDREEYMVASVARRLQ-GKAKEMSAFDAFN
MSMEG_4474|M.smegmatis_MC2_155 RQDNEEEGSLFNRGTQIKMFEDREEYMVASVARRLQ-GKAKEMSAFDAFN
TH_0727|M.thermoresistible__bu RQDSEEEGSLFNRGTQLQMFSDREEYMLSSVARRLQ-GKSKEMSEFDAYN
MMAR_3631|M.marinum_M RQDNEEEGSLFNRGTQVKMFEDREDYLLSSVARRLQ-NKSNEMSAFDAFN
MUL_1233|M.ulcerans_Agy99 RQDNEEEGSLFNRGTQVKMFEDREDYLLSSVARRLQ-NKSNEMSAFDAFN
MAV_2078|M.avium_104 RQDSEEEGSLFNRGTQIKMFEDREEYLLASVARRLQ-AKSKEMSEFDAFN
MLBr_00845|M.leprae_Br4923 RQDSEKKGSLFNRGTQGTIFEKCEDCLLSAVARRRQ-VKSKEMFAFDTFN
MAB_3588|M.abscessus_ATCC_1997 SDEDVEESDLSNRGTQLRLLRNREDHLLRTAATRMQRAQSDDEDPFEVFN
Mb2528c|M.bovis_AF2122/97 SVKYANQRQSFG----------QPIGAYQAIGFKIARMEARAHVARTAYY
Rv2500c|M.tuberculosis_H37Rv SVKYANQRQSFG----------QPIGAYQAIGFKIARMEARAHVARTAYY
. :: . . : . : :: .:
Mflv_2726|M.gilvum_PYR-GCK SVQDHVLHTAQAHIDRIILEAFVAGIDSCQDRQAREILGMVCDLYALSVI
Mvan_3808|M.vanbaalenii_PYR-1 SVQDHVLHVAQAHIERVVLEAFVAGIDACEDRLAREILGMVCDLYALSVI
MSMEG_4474|M.smegmatis_MC2_155 AVQDHVLHAAQAHIDRVILEAFVAGIDACEDEAARELLADVCDLYALSVI
TH_0727|M.thermoresistible__bu AVQDHVLHTARAHIDRVILEAFVAGIDACPDEEAAHILGMVCDLYALSVI
MMAR_3631|M.marinum_M AVQDHVLHAAQAHIDRVVLEAFVAGIESCTDEQARELLGVVCDLYALSVI
MUL_1233|M.ulcerans_Agy99 AVQDHVLHAAQAHIDRVVLEAFVAGIESCTDKQARELLGVVCDLYALSVI
MAV_2078|M.avium_104 SVQDHVLHAASAHIDRVVLEAFVAGIDGCPDEQARELLGILCDLYALSVI
MLBr_00845|M.leprae_Br4923 TVQDHLLHAANEHTDRVVLETFLAGIESCNDPAARKLLDIVCDLYALSVK
MAB_3588|M.abscessus_ATCC_1997 SAQDHILKVGSAHTERVVLEAFIEAIDSCDSKSAQELLEKLCDLFVYSAL
Mb2528c|M.bovis_AF2122/97 DAAAKMLAGKPFKKEAAIAKMISSEAAMDNSRDATQIHGGYGFMNEYPVA
Rv2500c|M.tuberculosis_H37Rv DAAAKMLAGKPFKKEAAIAKMISSEAAMDNSRDATQIHGGYGFMNEYPVA
. ::* : : : : : . * .: : ..
Mflv_2726|M.gilvum_PYR-GCK EEDK-AWFVEHRFLSTERAKAV-TRGINDRCRRLRPYAELLVDGFG--IP
Mvan_3808|M.vanbaalenii_PYR-1 EEDK-AWFVEHRFLSTERAKAV-TRGINDRCRRLRPYAELLVDGFG--IP
MSMEG_4474|M.smegmatis_MC2_155 EEDK-AWFIEHRFLSTERAKAV-TRGINERCRTLRPHAETLIDGFG--IP
TH_0727|M.thermoresistible__bu ERDE-AWFIKHRFLSTERAKAV-TRGINERCRTLRPYAELLVDGFG--IP
MMAR_3631|M.marinum_M EEDK-AWYIEHRYLSTERAKAV-TRGINDRCRVLRPHARTLVDGFG--IP
MUL_1233|M.ulcerans_Agy99 EEDK-AWYIEHRYLSTERAKAV-TRGINDRCRVLRPHARTLVDGFG--IL
MAV_2078|M.avium_104 EDDK-AWYIEHRYLSTERAKAV-TRGINDRCRALRPHAQTLVDGFG--IP
MLBr_00845|M.leprae_Br4923 ARHG-TSSIDTSPPSALKAIAKGSRPMPSAAALCRDVGRRFSESQSSCVT
MAB_3588|M.abscessus_ATCC_1997 EADL-SWFLMHRHVSTERAKAI-RRGVNQLCEELRPHLGTLVDAFG--IP
Mb2528c|M.bovis_AF2122/97 RHYRDSKVLEIGEGTTEVQLMLIARSLGLQ--------------------
Rv2500c|M.tuberculosis_H37Rv RHYRDSKVLEIGEGTTEVQLMLIARSLGLQ--------------------
: : :: * :
Mflv_2726|M.gilvum_PYR-GCK ENLRYAEMLHPENIPDADEHTSQDATSAGVI
Mvan_3808|M.vanbaalenii_PYR-1 EQLRYAEMLHPEHIPDADEHTRQDATSAGTI
MSMEG_4474|M.smegmatis_MC2_155 EQLRYAAMLDPEELLNG--------------
TH_0727|M.thermoresistible__bu EQLRDAEMLHPERILQAD-------------
MMAR_3631|M.marinum_M KPLRYAEMLHPENLPD---------------
MUL_1233|M.ulcerans_Agy99 KPLRYAEMLHPENLPD---------------
MAV_2078|M.avium_104 ERLRYAEMLHPENLSEALTS-----------
MLBr_00845|M.leprae_Br4923 PRCRTSRICPSELQPR---------------
MAB_3588|M.abscessus_ATCC_1997 EALLATEMIPDN-------------------
Mb2528c|M.bovis_AF2122/97 -------------------------------
Rv2500c|M.tuberculosis_H37Rv -------------------------------