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PLRPTNAASERVTKRTATETILQRMVGARQDSEKKGSLFNRGTQGTIFEKCEDCLLSAVARRRQVKSKEM FAFDTFNTVQDHLLHAANEHTDRVVLETFLAGIESCNDPAARKLLDIVCDLYALSVKARHGTSSIDTSPP SALKAIAKGSRPMPSAAALCRDVGRRFSESQSSCVTPRCRTSRICPSELQPR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_00845 | - | - | 100% (193) | hypothetical protein MLBr_00845 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2726 | - | 1e-38 | 61.98% (121) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3588 | - | 1e-18 | 36.13% (119) | putative acyl-CoA oxidase |
| M. marinum M | MMAR_3631 | - | 5e-42 | 69.42% (121) | acyl-CoA dehydrogenase |
| M. avium 104 | MAV_2078 | - | 1e-40 | 66.94% (121) | acyl-CoA oxidase |
| M. smegmatis MC2 155 | MSMEG_4474 | - | 2e-38 | 62.81% (121) | acyl-CoA oxidase |
| M. thermoresistible (build 8) | TH_0727 | - | 5e-35 | 57.26% (124) | acyl-CoA oxidase |
| M. ulcerans Agy99 | MUL_1233 | - | 7e-41 | 68.60% (121) | acyl-CoA dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_3808 | - | 4e-37 | 60.50% (119) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2726|M.gilvum_PYR-GCK ----------------MTTTAEHLRNSLDGRFRDVKNRVRRELSDDVFRP
Mvan_3808|M.vanbaalenii_PYR-1 MRHHGLRIPRDGYRPDMTTTAEHLRNSLDGRFRDVKNRVRRELSDEVFRP
MSMEG_4474|M.smegmatis_MC2_155 ----------------MTTTAEHLRNALDGRWRDVKNAMRENLSNEVFRP
TH_0727|M.thermoresistible__bu ----------------MTTTAEHLRNALDGRWRDVKNEMRERLSDEVFRP
MAB_3588|M.abscessus_ATCC_1997 -------METRTAPADPEVLTSNLRVALDGRFGPIRDAAREYLNRADLLP
MAV_2078|M.avium_104 ------------MAPETTSTAEHLRNALDGRWRDVRNRMRETLSEDLFRP
MMAR_3631|M.marinum_M ------------MAPDMTNTAKHLRDALDGRFRDVKNEMRQQLTLEIFRP
MUL_1233|M.ulcerans_Agy99 ------------MAPDMTNTAKHLRDALDGRFRDVKNAMRQQLTLEIFRP
MLBr_00845|M.leprae_Br4923 --------------------------------------------------
Mflv_2726|M.gilvum_PYR-GCK HYTPNTVIARTKVAEQMKIMAARGAAEDGFKKEHGGNGDVGAAVTQIEML
Mvan_3808|M.vanbaalenii_PYR-1 HYTPNTVIARTKVAEQLKIMAAQGAAEDGFKKEHGGNGDVGAAVTQIEML
MSMEG_4474|M.smegmatis_MC2_155 HYTPNTAIARAKVAEQLKIMAAAGAAEDGFRKEHGGNGNVGAAIAQIEML
TH_0727|M.thermoresistible__bu HFTPNTVIARTKVNEQLRIMAAAGAAEDGFRKEHGGTGDVGAAITRIEML
MAB_3588|M.abscessus_ATCC_1997 DPSLTLEQARARSLRIMRELVPHGLPHAGFRTEHGGTGDVGAAIVGIEML
MAV_2078|M.avium_104 HYTPNTVIARTKVAEQMRIMAAFGAAADGFRKEHGGTGDVGAAITMIEML
MMAR_3631|M.marinum_M HYTPNTVIARAKVAEQMKFMAGAGAAEDSFRKEHGGTGNVGAAITMIEML
MUL_1233|M.ulcerans_Agy99 HYTPNTVIARAKVAEQMRFMAGAGAAEDSFRKEHGGTGNVGAAITMIEML
MLBr_00845|M.leprae_Br4923 --------------------------------------------------
Mflv_2726|M.gilvum_PYR-GCK AMSDLSLMVKAGVQWGLFGGAIENLGTERHHAAYVKKLINLEVLGCFAMT
Mvan_3808|M.vanbaalenii_PYR-1 AMSDLSLMVKAGVQWGLFGGAIENLGTERHHKAYVKKLIDLELLGCFAMT
MSMEG_4474|M.smegmatis_MC2_155 AMSDLSLMVKAGVQWGLFGGAIENLGTERHHQAYVRRIIDLDLLGCFAMT
TH_0727|M.thermoresistible__bu AMSDLSLMVKAGVQWGLFGGAIENLGTERHHRKYVRRIIDCDLLGCFAMT
MAB_3588|M.abscessus_ATCC_1997 GYADLSLMVKAGVQWGLFGGAIENLGTATHHEQYVVPLINLDVLGCFGMT
MAV_2078|M.avium_104 AMSDLSLMVKAGVQWGLFGGAVENLGTERHHETYVPKIISLELRGCFAMT
MMAR_3631|M.marinum_M AMSDLSLMVKAGVQWGLFGGAVENLGTERHHEQYVPKIIDLQLRGCFAMT
MUL_1233|M.ulcerans_Agy99 AMSDLSLMVKAGVQWGLFGGAVENLGTERHHEQYVPKIIDLQLRGCFAMT
MLBr_00845|M.leprae_Br4923 --------------------------------------------------
Mflv_2726|M.gilvum_PYR-GCK ETGHGSDVQSLETTATYDPATQEFVIDSPTPSSRKDYIGGAAETARVAAV
Mvan_3808|M.vanbaalenii_PYR-1 ETGHGSDVQSLETTATYDPATEEFVIDSPTRTSRKDYIGGAAETARVAAV
MSMEG_4474|M.smegmatis_MC2_155 ETGHGSDVQSIETTATYDPATQEFVIHSPTPTARKDYIGGAAETARVAAV
TH_0727|M.thermoresistible__bu ETGHGSNVQALETTATYDPATREFVIHSPTPTSRKDYIGGAAQTARMAAV
MAB_3588|M.abscessus_ATCC_1997 ETGHGSNVQALQTVATYDRTTGDFVLNSEGSLARKDYIGGAAEHATVSAV
MAV_2078|M.avium_104 ETGHGSDVQSLETTATYDPATEEFVIDSPTPSARKDYIGGAAETATVAAV
MMAR_3631|M.marinum_M ETGHGSDVQSLETTATYDADTEEFIIDSPTPTARKDYIGGAAETATIAAV
MUL_1233|M.ulcerans_Agy99 ETGHGSDVQSLETTATYDADTEEFIIDPPTPTARKDYIGGAAETATIAAV
MLBr_00845|M.leprae_Br4923 --------------------------------------------------
Mflv_2726|M.gilvum_PYR-GCK FAQLIT-PDG---VKHGVHCFVVPIRDEQGEDLPGVTTSDCHYKGGLPGV
Mvan_3808|M.vanbaalenii_PYR-1 FAQLIT-PDG---ETHGVHCFVVPIRDDDGNDLPGVTTSDCHYKGGLPGV
MSMEG_4474|M.smegmatis_MC2_155 FAQLIT-PDG---MNHGVHCLVVPIRDDEGNDLPGVTTSDCHYKGGLPGV
TH_0727|M.thermoresistible__bu FAQLIT-HEDGAPVQHGVHCLLVPLRDEDGNDLPGVTTSDNDYKGGLPGV
MAB_3588|M.abscessus_ATCC_1997 FAQLVTGGPGEEATGRGVHCFVVPIRDADGNDLPGITTSDCGYKGGLAGV
MAV_2078|M.avium_104 FAQLITTEDG-KPVNHGVHCLLVPIRDADGNDLPGVTTSDCEYKGGLPGV
MMAR_3631|M.marinum_M FAQLITQIDG-EQANHGVHCFLVPIRDEDGNDLPGVTTSDCHYKGGLPGV
MUL_1233|M.ulcerans_Agy99 FAQLITQIDG-EQANHGVHCFLVPIRDEDGNDLPGVTTSDCHYKGGLPDV
MLBr_00845|M.leprae_Br4923 --------------------------------------------------
Mflv_2726|M.gilvum_PYR-GCK DNGRIQFDEVRIPRENLLNKYADVAEDGTYSSPIENPNRRFFTMLGTLIR
Mvan_3808|M.vanbaalenii_PYR-1 DNGRIQFDQVRVPRENLLNRYADVAADGTYTSPIENPNRRFFTMLGTLIR
MSMEG_4474|M.smegmatis_MC2_155 DNGRIVFDHVRVPRENLLNRYADVSPEGVYSSPIENPGRRFFTMLGTLIR
TH_0727|M.thermoresistible__bu DNGRIMFDHVRVPRENLLNRYGDVSEDGTYTSPIESPGRRFFTMLGTLVR
MAB_3588|M.abscessus_ATCC_1997 DNGRIVFDNVRVPRANLLNRYADVAEDGTYSSPIENENKRFFTMLGTLIR
MAV_2078|M.avium_104 DNGRIVFDHVRVPRVNLLNKYGDVAPDGTYSSPIENPNRRFFTMLGTLVR
MMAR_3631|M.marinum_M DNGRITFDHVRIPRVNLLNRYGDVATDGTYSSPIDNPNRRFFTMIGTLIR
MUL_1233|M.ulcerans_Agy99 DNGRITFDHVRIPWVNLLNRYGDVATDGTYSSPIDNPNRRFFTMIGTLIR
MLBr_00845|M.leprae_Br4923 --------------------------------------------------
Mflv_2726|M.gilvum_PYR-GCK GRVTVGGSAGAAARVALDIATRYALQRRQFEDPDG--GEVLLMDYLVHQR
Mvan_3808|M.vanbaalenii_PYR-1 GRVTVGGSAGAAARVALDIATRYALQRRQFSDPDG--GEVLLMDYLVHQR
MSMEG_4474|M.smegmatis_MC2_155 GRVTVGGSAAAAARVALDIATRYALQRTQFSAPDDE-HEVVIMDYLVHQR
TH_0727|M.thermoresistible__bu GRVTVGGSASAAARVALDIATRYALQRRQFSGPGDDDTEVLIMDYLVHQR
MAB_3588|M.abscessus_ATCC_1997 GRVSVAATSGAAARKALTIASRYALVRKQFDTPDSD-DEVIIADYLVHQR
MAV_2078|M.avium_104 GRITVGGSAGAAGRVALDIATRYALQRKQFTTPDGD-SEVLIMDYLVHQR
MMAR_3631|M.marinum_M GRVTVGGSAAAAARVALDIATRYALQRRQFSAPDDDDTEVLIMDYLMHQR
MUL_1233|M.ulcerans_Agy99 GRVTVGGSAAAAARVALDIATRYALQRRQFSAPDDDDTEVLIMDYLMHQR
MLBr_00845|M.leprae_Br4923 --------------------------------------------------
Mflv_2726|M.gilvum_PYR-GCK RLFPLIARSYALQYAQNELVARCHELQTADDPDPEDQRELESRAAGLKAA
Mvan_3808|M.vanbaalenii_PYR-1 RLFPLIARSYALQFAQNELVAKCHELQTADDPDPEEQRELESRAAGLKAA
MSMEG_4474|M.smegmatis_MC2_155 RLLPLIAKSYALQFAQNELVAKCHELQTSDDPDPEEQRELEARAAGLKAA
TH_0727|M.thermoresistible__bu RLFPLIAESYALQFAQNELVAKCHDLQSQDDPDPEEQRELEARAAGLKAV
MAB_3588|M.abscessus_ATCC_1997 KLLPLIARSYALAFAQNELTEELHQVQTADEVDADRQRQLESAAAGLKAM
MAV_2078|M.avium_104 RLFPLIAKSYALQFAQNELVSKCHDIQSADDPDADEQRELEARAAGLKAA
MMAR_3631|M.marinum_M RLFPLIARSYALQFAQNELVSKCHDLQTTDSPDAEEQRELEARAAGLKAA
MUL_1233|M.ulcerans_Agy99 RLFPLIARSYALQFAQNELVSKCHDLQTTDSPDAEEQRELEARAAGLKAA
MLBr_00845|M.leprae_Br4923 --------------------------------------------------
Mflv_2726|M.gilvum_PYR-GCK NTWHATRAIQEAREACGGAGYLAENRLIALKADTDVFTTFEGDNHVLFQL
Mvan_3808|M.vanbaalenii_PYR-1 NTWHATRAIQEAREACGGAGYMAENRLIALKADTDVFTTFEGDNHVLYQL
MSMEG_4474|M.smegmatis_MC2_155 NTWHASTAIQEAREACGGAGYLAENRLIALRADTDVFTTFEGDNHVLTQL
TH_0727|M.thermoresistible__bu GTWHASRAIQESREACGGAGYMGENRLVGLRGDIDVFTTFEGDNTVMLQQ
MAB_3588|M.abscessus_ATCC_1997 TSWHAQHAITVCREACGGAGYLDANQLTILRRDIDVFTTFEGDNTVLTQL
MAV_2078|M.avium_104 NTWHATRAIQESREACGGAGYMAENRLIALRGDTDVFTTFEGDNHVLTQL
MMAR_3631|M.marinum_M NTWHASRAIQEAREACGGAGYMAENRLIALRADTDVFTTFEGDNHVLTQL
MUL_1233|M.ulcerans_Agy99 NTWHASRAIQEAREACGGTGYMAENRLIALRADTDVFTTFEGDNHVLTQL
MLBr_00845|M.leprae_Br4923 ---------------------------MPLR-------------------
*:
Mflv_2726|M.gilvum_PYR-GCK VAKELLTAYADDIKGMSPVDWVRFAANFAGERVLKRTAAQTIMQTILDTR
Mvan_3808|M.vanbaalenii_PYR-1 VAKELLTAYADDIKGMSPVEWVRFAASFAGERVLKRTAAQTIMQTVLDTR
MSMEG_4474|M.smegmatis_MC2_155 VAKELLTAYADDIKGMSPVEWVRFAANFAGERVLKRTAAQTIIQTILDTR
TH_0727|M.thermoresistible__bu VAKGLLTAYADDVRSMSPVEWVRFAANTVGTRVLKRTAAQPIIQTILDNR
MAB_3588|M.abscessus_ATCC_1997 VAKELLSAYAEDVRGLNAVGWTRFIAGMARDVILERSAARQVIQTILDSS
MAV_2078|M.avium_104 VAKELLTAYADDIKSMSPVEWVRFAANAVGDRVIKRTAAETIIQTIVDAR
MMAR_3631|M.marinum_M VAKELLTAYADDIRSMSPVEWVRFAANAVGDRVMKRTAAEAIMQRIVDAR
MUL_1233|M.ulcerans_Agy99 VAKELLTAYADDIRSMSPVEWVRFAANAVGDWVMKRTAAEAITQRIVDAR
MLBr_00845|M.leprae_Br4923 ------------------------PTNAASERVTKRTATETILQRMVGAR
:. . : :*:*:. : * ::.
Mflv_2726|M.gilvum_PYR-GCK EDNEEEGSLFNRGTQVQMFEDREQYMLSSVARRIQ-SKSKEMGAFDAFNS
Mvan_3808|M.vanbaalenii_PYR-1 QDNEEEGSLFNRGTQVKMFEDREEYMVASVARRLQ-GKAKEMSAFDAFNS
MSMEG_4474|M.smegmatis_MC2_155 QDNEEEGSLFNRGTQIKMFEDREEYMVASVARRLQ-GKAKEMSAFDAFNA
TH_0727|M.thermoresistible__bu QDSEEEGSLFNRGTQLQMFSDREEYMLSSVARRLQ-GKSKEMSEFDAYNA
MAB_3588|M.abscessus_ATCC_1997 DEDVEESDLSNRGTQLRLLRNREDHLLRTAATRMQRAQSDDEDPFEVFNS
MAV_2078|M.avium_104 QDSEEEGSLFNRGTQIKMFEDREEYLLASVARRLQ-AKSKEMSEFDAFNS
MMAR_3631|M.marinum_M QDNEEEGSLFNRGTQVKMFEDREDYLLSSVARRLQ-NKSNEMSAFDAFNA
MUL_1233|M.ulcerans_Agy99 QDNEEEGSLFNRGTQVKMFEDREDYLLSSVARRLQ-NKSNEMSAFDAFNA
MLBr_00845|M.leprae_Br4923 QDSEKKGSLFNRGTQGTIFEKCEDCLLSAVARRRQ-VKSKEMFAFDTFNT
::. ::..* ***** :: . *: :: :.* * * ::.: *:.:*:
Mflv_2726|M.gilvum_PYR-GCK VQDHVLHTAQAHIDRIILEAFVAGIDSCQDRQAREILGMVCDLYALSVIE
Mvan_3808|M.vanbaalenii_PYR-1 VQDHVLHVAQAHIERVVLEAFVAGIDACEDRLAREILGMVCDLYALSVIE
MSMEG_4474|M.smegmatis_MC2_155 VQDHVLHAAQAHIDRVILEAFVAGIDACEDEAARELLADVCDLYALSVIE
TH_0727|M.thermoresistible__bu VQDHVLHTARAHIDRVILEAFVAGIDACPDEEAAHILGMVCDLYALSVIE
MAB_3588|M.abscessus_ATCC_1997 AQDHILKVGSAHTERVVLEAFIEAIDSCDSKSAQELLEKLCDLFVYSALE
MAV_2078|M.avium_104 VQDHVLHAASAHIDRVVLEAFVAGIDGCPDEQARELLGILCDLYALSVIE
MMAR_3631|M.marinum_M VQDHVLHAAQAHIDRVVLEAFVAGIESCTDEQARELLGVVCDLYALSVIE
MUL_1233|M.ulcerans_Agy99 VQDHVLHAAQAHIDRVVLEAFVAGIESCTDKQARELLGVVCDLYALSVIE
MLBr_00845|M.leprae_Br4923 VQDHLLHAANEHTDRVVLETFLAGIESCNDPAARKLLDIVCDLYALSVKA
.***:*:.. * :*::**:*: .*:.* . * .:* :***:. *.
Mflv_2726|M.gilvum_PYR-GCK EDKAWFVEHRFLSTERAKAVT-RGINDRCRRLRPYAELLVDGFG--IPEN
Mvan_3808|M.vanbaalenii_PYR-1 EDKAWFVEHRFLSTERAKAVT-RGINDRCRRLRPYAELLVDGFG--IPEQ
MSMEG_4474|M.smegmatis_MC2_155 EDKAWFIEHRFLSTERAKAVT-RGINERCRTLRPHAETLIDGFG--IPEQ
TH_0727|M.thermoresistible__bu RDEAWFIKHRFLSTERAKAVT-RGINERCRTLRPYAELLVDGFG--IPEQ
MAB_3588|M.abscessus_ATCC_1997 ADLSWFLMHRHVSTERAKAIR-RGVNQLCEELRPHLGTLVDAFG--IPEA
MAV_2078|M.avium_104 DDKAWYIEHRYLSTERAKAVT-RGINDRCRALRPHAQTLVDGFG--IPER
MMAR_3631|M.marinum_M EDKAWYIEHRYLSTERAKAVT-RGINDRCRVLRPHARTLVDGFG--IPKP
MUL_1233|M.ulcerans_Agy99 EDKAWYIEHRYLSTERAKAVT-RGINDRCRVLRPHARTLVDGFG--ILKP
MLBr_00845|M.leprae_Br4923 RHGTSSIDTSPPSALKAIAKGSRPMPSAAALCRDVGRRFSESQSSCVTPR
. : : *: :* * * : . . * : :. . :
Mflv_2726|M.gilvum_PYR-GCK LRYAEMLHPENIPDADEHTSQDATSAGVI
Mvan_3808|M.vanbaalenii_PYR-1 LRYAEMLHPEHIPDADEHTRQDATSAGTI
MSMEG_4474|M.smegmatis_MC2_155 LRYAAMLDPEELLNG--------------
TH_0727|M.thermoresistible__bu LRDAEMLHPERILQAD-------------
MAB_3588|M.abscessus_ATCC_1997 LLATEMIPDN-------------------
MAV_2078|M.avium_104 LRYAEMLHPENLSEALTS-----------
MMAR_3631|M.marinum_M LRYAEMLHPENLPD---------------
MUL_1233|M.ulcerans_Agy99 LRYAEMLHPENLPD---------------
MLBr_00845|M.leprae_Br4923 CRTSRICPSELQPR---------------
: : :