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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_0643 | - | - | 100% (318) | amidohydrolase 3 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2078c | - | 2e-13 | 35.14% (185) | hypothetical protein Mb2078c |
| M. gilvum PYR-GCK | Mflv_0443 | - | 1e-109 | 63.17% (315) | amidohydrolase 3 |
| M. tuberculosis H37Rv | Rv2052c | - | 2e-13 | 35.14% (185) | hypothetical protein Rv2052c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1868c | - | 8e-10 | 30.94% (181) | hypothetical protein MAB_1868c |
| M. marinum M | MMAR_0459 | - | 1e-109 | 63.26% (313) | hypothetical protein MMAR_0459 |
| M. avium 104 | MAV_4955 | - | 1e-117 | 64.86% (313) | amidohydrolase family protein |
| M. smegmatis MC2 155 | MSMEG_0263 | - | 1e-107 | 60.63% (315) | amidohydrolase 3 |
| M. ulcerans Agy99 | MUL_1109 | - | 1e-110 | 63.26% (313) | hypothetical protein MUL_1109 |
| M. vanbaalenii PYR-1 | Mvan_0224 | - | 1e-109 | 63.17% (315) | amidohydrolase 3 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2078c|M.bovis_AF2122/97 MSQIPVKLLVNGRVYSPTHP------------------------------
Rv2052c|M.tuberculosis_H37Rv MSQIPVKLLVNGRVYSPTHP------------------------------
Mflv_0443|M.gilvum_PYR-GCK -MLIRNAVLIDG--------------------------------------
Mvan_0224|M.vanbaalenii_PYR-1 -MLIRRAALLDG--------------------------------------
MSMEG_0263|M.smegmatis_MC2_155 -MLIQRASLLDG--------------------------------------
MMAR_0459|M.marinum_M -MLIRRATLLDG--------------------------------------
MUL_1109|M.ulcerans_Agy99 --------------------------------------------------
MAV_4955|M.avium_104 -MLIQRATLLDG--------------------------------------
TH_0643|M.thermoresistible__bu --------------------------------------------------
MAB_1868c|M.abscessus_ATCC_199 MSINRRQFVVGGAAATAATTGLAALAGCGHDTTDPDTGADLIFVGGPVVT
Mb2078c|M.bovis_AF2122/97 ------EATAMAVRGDVVAWLGSDDVGRDQF-PDADVQDLDGRFVAPGFV
Rv2052c|M.tuberculosis_H37Rv ------EATAMAVRGDVVAWLGSDDVGRDQF-PDADVQDLDGRFVAPGFV
Mflv_0443|M.gilvum_PYR-GCK -------TRTDIRVGDTVTEVA---DDVTAA-PGEDEFDAAGGTVLPGLN
Mvan_0224|M.vanbaalenii_PYR-1 -------TRTDIRVGERITGMA---DGLTAE-PGETEYDAAGGAVIPGLH
MSMEG_0263|M.smegmatis_MC2_155 -------RIADIRVGEAIEDVG---PSLRAR-RGEAVLDAALGAVIPGLH
MMAR_0459|M.marinum_M -------STADIRVCARIQEVG---QGLVAR-PGERVLDAAGQTVLPGLH
MUL_1109|M.ulcerans_Agy99 -------------MCARIQEVG---QGLVAR-PGERVLDAAGQTVLPGLH
MAV_4955|M.avium_104 -------TAADIRVGARIEEVAPADDGLAAR-AGEGVLYAGGGTVLPGLH
TH_0643|M.thermoresistible__bu --------------------------------------------------
MAB_1868c|M.abscessus_ATCC_199 VDGHGTTTEALAVAQGKIAAVGSRQDVMRLRGAQTDVIELDGLALLPAFV
Mb2078c|M.bovis_AF2122/97 DSHIHLT-------ATGLMLSGLDLRPATSRAQCLRMVADYAADHPGQPL
Rv2052c|M.tuberculosis_H37Rv DSHIHLT-------ATGLMLSGLDLRPATSRAQCLRMVADYAADHPGQPL
Mflv_0443|M.gilvum_PYR-GCK DHHLHLR-------AAAAALRSLRVGPDEVRDRAA-LAGVLAAAVPDQ--
Mvan_0224|M.vanbaalenii_PYR-1 DHHIHLR-------AAAAALHSVRVGPDEVHSRAE-LAETLAAATVGA--
MSMEG_0263|M.smegmatis_MC2_155 DHHVHVY-------SAAAEQNSLRVGPREAHDTGE-LRRLLAGAAPGA--
MMAR_0459|M.marinum_M DHHVHLR-------SAASALDSLTLGPPTVDSKEK-FRQHLSSAQPGP--
MUL_1109|M.ulcerans_Agy99 DHHVHLRSHHVHLRSAASAVDSLTLGPPTVDSKEK-FRQHLSSAQPGP--
MAV_4955|M.avium_104 DHHVHLR-------SAASALDSFFVGPPGVSTRAE-LTRLLANATPGP--
TH_0643|M.thermoresistible__bu --------------------------------------------------
MAB_1868c|M.abscessus_ATCC_199 EAHSHPS-----QIAATLGPPAVDVRPFVVPTGQQVMQKLADTVRSTPKG
Mb2078c|M.bovis_AF2122/97 WGHGWDESAWPENAAPSTADLDAVLGDCPAYLARIDSHSALVSSGLRRLV
Rv2052c|M.tuberculosis_H37Rv WGHGWDESAWPENAAPSTADLDAVLGDCPAYLARIDSHSALVSSGLRRLV
Mflv_0443|M.gilvum_PYR-GCK --NGWIRAVGYHDSVAGPLTRDLLDAIAPEVPVRIQHR-----SGVQWTL
Mvan_0224|M.vanbaalenii_PYR-1 --DGWIRAVGYHDAAAGPLDRHVLDELAPSVPVRIQHR-----SGAQWIL
MSMEG_0263|M.smegmatis_MC2_155 --DGWIRAIGYHEQVAGPLDRDRLDALAPAVPVRVQHR-----SGVLWVL
MMAR_0459|M.marinum_M --DGWIRAVGYHESVAGPLDRTVLDALVPHLPVRVQHR-----SGALWIL
MUL_1109|M.ulcerans_Agy99 --DGWIRAVGYHEAVAGPLDRTVLDALVPHLPVRVQHR-----SGALWIL
MAV_4955|M.avium_104 --DGWIRAVGYHDSVAGALDRTALDAIVRDVPVRIQHR-----SGALWIL
TH_0643|M.thermoresistible__bu ------------------------------VPVRVQHR-----SGVLWTL
MAB_1868c|M.abscessus_ATCC_199 TQVLLYGIDVLLQPDLQLPTRTILDALAPDHPVIIVAN-----SGHAAYA
. : . **
Mb2078c|M.bovis_AF2122/97 PELAAATGYTA------------QRPLTGDAHHLARAAARYLLTDVQLAD
Rv2052c|M.tuberculosis_H37Rv PELAAATGYTA------------QRPLTGDAHHLARAAARYLLTDVQLAD
Mflv_0443|M.gilvum_PYR-GCK NTAGLALVGKH------------DHPDG----VLRSADPSWTLPA--TEP
Mvan_0224|M.vanbaalenii_PYR-1 NTAALRRVGLA------------DHPDG----RLPSADGSWAATLR-SDP
MSMEG_0263|M.smegmatis_MC2_155 NSAGLAAINRP------------DHPDG----ILRSADPTWAEALPRRDT
MMAR_0459|M.marinum_M NSAALNRIGLA------------GHVDG----RLRSADSDWSDALPRRKT
MUL_1109|M.ulcerans_Agy99 NSAALNRIGLA------------GHVDG----RLRSADSDWSDALPRRKT
MAV_4955|M.avium_104 NSEALGRIGLA------------EHPDG----RLRSADRGWSQALAHRET
TH_0643|M.thermoresistible__bu NSAGLARIGMP------------DHPDG----RLRSADPDWSNSLQRRET
MAB_1868c|M.abscessus_ATCC_199 NTASFRLAGITRDTPNPVGAEYVHGPDGELTGEVREAAALTTLAMPYLRN
. : * .
Mb2078c|M.bovis_AF2122/97 ARAVALQA--------IAAAGVVAVHECAGPEIGGLDDWLRLRAL-----
Rv2052c|M.tuberculosis_H37Rv ARAVALQA--------IAAAGVVAVHECAGPEIGGLDDWLRLRAL-----
Mflv_0443|M.gilvum_PYR-GCK DLEGLGAT--------LSRYGITGVTDAT-PDLGAGD-------------
Mvan_0224|M.vanbaalenii_PYR-1 GLDELGAL--------LCRYGVTGVTDAT-PDLAAGD-------------
MSMEG_0263|M.smegmatis_MC2_155 DIDSYAER--------LARYGITGITDAT-PDLSE---------------
MMAR_0459|M.marinum_M DLAALGDR--------LTAAGVTGVTDAT-PDLSDEDMAA----------
MUL_1109|M.ulcerans_Agy99 DLAELGDR--------LTAAGVTGVTDAT-PDLSDEDMAA----------
MAV_4955|M.avium_104 DLAELSRR--------ITATGVTGVTDAT-PDLDDDDRAA----------
TH_0643|M.thermoresistible__bu RIADLSAE--------LTRYGVTGVTDAT-PGLDVGDVVR----------
MAB_1868c|M.abscessus_ATCC_199 VAEPNAFQNLHWAFGQLAAVGIATASEHSYSAAQQGDLYRRMAADPGVKL
: *:. : : .
Mb2078c|M.bovis_AF2122/97 -----EHGVEVIGYWGEAVATPAQARDLVTETG-----ARGLAGDLFVDG
Rv2052c|M.tuberculosis_H37Rv -----EHGVEVIGYWGEAVATPAQARDLVTETG-----ARGLAGDLFVDG
Mflv_0443|M.gilvum_PYR-GCK -------ITELQRRMPQTVRALAPGKRILHDD------------------
Mvan_0224|M.vanbaalenii_PYR-1 -------VAALQREMRQRVRCLAPGKRILHDD------------------
MSMEG_0263|M.smegmatis_MC2_155 ----------PPRGLPQHLHVLAPGKKILHDD------------------
MMAR_0459|M.marinum_M -----LTVAHQRGEFRPRVRFLSPGKKILRDD------------------
MUL_1109|M.ulcerans_Agy99 -----LTVAHQRGEFRPRVRFLSPGKKILRDD------------------
MAV_4955|M.avium_104 -----LAAAHARGEFRPRPSFLSPGKKILHDD------------------
TH_0643|M.thermoresistible__bu -----LTGMNRRGNLSQRVNCLAPGKRILHDD------------------
MAB_1868c|M.abscessus_ATCC_199 RIRAYEMGAPELAKDPTHVAGPAAGADQLFAQIGMKLWADGSPWQGNIFT
: . :
Mb2078c|M.bovis_AF2122/97 ALGSRTAWLHEPYADAPDCIGTCHLDVDGIEAHVRACTKAEVTAGFHVIG
Rv2052c|M.tuberculosis_H37Rv ALGSRTAWLHEPYADAPDCIGTCHLDVDGIEAHVRACTKAEVTAGFHVIG
Mflv_0443|M.gilvum_PYR-GCK -----------------------ELDLDALTSWIRHTHSVGVPVALHCVT
Mvan_0224|M.vanbaalenii_PYR-1 -----------------------ELDPDELSRWIGDRHAEGFPVAVHCVT
MSMEG_0263|M.smegmatis_MC2_155 -----------------------MLDLDGLVTWIGERHARGVPVAVHCVT
MMAR_0459|M.marinum_M -----------------------HLDLEALMAWITDSHGAGQPVAIHCVT
MUL_1109|M.ulcerans_Agy99 -----------------------HLDLETLMAWITDSHGAGQPVAIHCVT
MAV_4955|M.avium_104 -----------------------RLNLDALTEWVAGQHDTGQPVAVHCVT
TH_0643|M.thermoresistible__bu -----------------------RLDLTELTEWIATRHAAGGAVAIHCVT
MAB_1868c|M.abscessus_ATCC_199 SFPYLDTAATRRMGLEPHHHGGMNYTPAQVTELATAFIEQGWQLACHVHG
: . *
Mb2078c|M.bovis_AF2122/97 DAAVSAAVAAFERVVADLGVVAVARCGHRLEHVEMVTADQAAKLGAWGVI
Rv2052c|M.tuberculosis_H37Rv DAAVSAAVAAFERVVADLGVVAVARCGHRLEHVEMVTADQAAKLGAWGVI
Mflv_0443|M.gilvum_PYR-GCK AAQLVVTLTALRSAGRHP--------LDRIEHAAVVPDGSVADLADSGVT
Mvan_0224|M.vanbaalenii_PYR-1 AAQLVVTLEALRSSGTHP--------LDRIEHAAVVPDGSLADLAGRAVT
MSMEG_0263|M.smegmatis_MC2_155 SAQLVVTIAAMRVTGVLP--------GDRIEHAAMVPEDCVRDLCELGVT
MMAR_0459|M.marinum_M AAQLVVTIAAVRAVGRHP--------HDRIEHAAVVPDDLVADLAGLGLT
MUL_1109|M.ulcerans_Agy99 AAQLVVTIAAVRAVGRHP--------HDRIEHAAVVPDDLVADLAGLGLT
MAV_4955|M.avium_104 AAQLVVAIAALRAAGTHP--------RDRIEHAAVVPDDNLADLAELGVT
TH_0643|M.thermoresistible__bu AAQLVVTLTALRAVGTHP--------QDRIEHAAVVPDDSLEEIAALGLT
MAB_1868c|M.abscessus_ATCC_199 DRAIDVVLDAYEKAQSPAS------LRSRLEHVGAMTPAQFQRAARLGVH
: ..: * . *:**. :. .:
Mb2078c|M.bovis_AF2122/97 ASVQPNFDELWGGGDGMYARRLGAQRGSELNP-LALLASQGVPLALGSDA
Rv2052c|M.tuberculosis_H37Rv ASVQPNFDELWGGGDGMYARRLGAQRGSELNP-LALLASQGVPLALGSDA
Mflv_0443|M.gilvum_PYR-GCK VVTQPNFVAERGD---QYLVDVPEHEHHELWR-VGSLLEAGVPVALSTDA
Mvan_0224|M.vanbaalenii_PYR-1 VVTQPNFVAERGD---QYLADVAPAEQPELWR-VASLLRAGVPVALSTDA
MSMEG_0263|M.smegmatis_MC2_155 VVTQPNFVTERGD---AYRSDVDAADHHQLWR-VATLLAAGVRVALSTDA
MMAR_0459|M.marinum_M VVTQPNFVAERGD---QYLDEIPAAEHGQLWR-VASLLNANVPVAFSTDL
MUL_1109|M.ulcerans_Agy99 VVTQPNFVAERGD---QYLDEIPAAEHGQLWR-VASLLNANVPVALSTDL
MAV_4955|M.avium_104 VVTQPNFVAERGD---QYLAEVPADEHDQLWR-LASLRDARVPVALSTDM
TH_0643|M.thermoresistible__bu VVTQPNFIAERGD---QYRTDVPADEHHELWR-LKSLLDAGIPTALSTDA
MAB_1868c|M.abscessus_ATCC_199 PSLFIEHVYFWGD---PLIDELFGQDHGAHWMSAKSALDAGLRISFHNDG
:. *. : : :: .*
Mb2078c|M.bovis_AF2122/97 PVTGFDPWASVRAAVNHRTP-GSGVS--ARAAFAAATRGGWRAGGVRDGR
Rv2052c|M.tuberculosis_H37Rv PVTGFDPWASVRAAVNHRTP-GSGVS--ARAAFAAATRGGWRAGGVRDGR
Mflv_0443|M.gilvum_PYR-GCK PFGHSDPWAAMRAAVHRRTP-SGTVLGPNERITEATALAMFTGN--RAGH
Mvan_0224|M.vanbaalenii_PYR-1 PFGDADPWAAMRAAVFRRTP-AGHVLGEAECVPASAALQMFLGDPGRPAT
MSMEG_0263|M.smegmatis_MC2_155 PFGDADPWAVMRAAVHRRTP-HGFVLNPAERIPPRTALELFFGTAQDPAH
MMAR_0459|M.marinum_M PFGSGDPWAAMRAAVHRRTP-RGVVLGVDECVTARAALTMFLGRPDQPGR
MUL_1109|M.ulcerans_Agy99 PFGSGDPWAPMRAAVHRRTP-RGVVLGVDECVTARAALTMFLGRPDQPGR
MAV_4955|M.avium_104 PFGHGDPWTAMRAAVHRTTP-SGVVLGARECVSARTALTMFLGRADQPDR
TH_0643|M.thermoresistible__bu PFGDADPWAAMRAAVHRTTG-SGAVLGADERIDAGTALRMFFGTADRPTR
MAB_1868c|M.abscessus_ATCC_199 NVSPPNPLGNIATAVTRTAKGSGRVLAPEQRISVTQAVRAQTIDAAWQLH
. :* : :** : : . * . :
Mb2078c|M.bovis_AF2122/97 IG----TLVPGAPASYAIWDAGDFDVDAPRDAVQRWSTDPRSRVPALPRL
Rv2052c|M.tuberculosis_H37Rv IG----TLVPGAPASYAIWDAGDFDVDAPRDAVQRWSTDPRSRVPALPRL
Mflv_0443|M.gilvum_PYR-GCK PG----AVVPGAPGDLCILAT------PPPQALAELDAAAVA--------
Mvan_0224|M.vanbaalenii_PYR-1 PR----RVEPGAAADLCILST------PPEATLAELDAAAVA--------
MSMEG_0263|M.smegmatis_MC2_155 PR----RVDVGQPGDLCVLAA------PPRQVVETLDADLVA--------
MMAR_0459|M.marinum_M VR----AVAAGQPGDLCVLAQ------TPAMVLTELDASLVS--------
MUL_1109|M.ulcerans_Agy99 VR----AVAAGQPGDLCVLAQ------TPAVVLTELDASLVS--------
MAV_4955|M.avium_104 VR----SVQPGEPGDLCVLNE------PPHTALAELDAGMVA--------
TH_0643|M.thermoresistible__bu PR----TVEPGQPADLCVLSA------PPDRVLRELSAELVS--------
MAB_1868c|M.abscessus_ATCC_199 LDNEVGSLEVGKYADLVVLSAD-----PHAVDPQALRDISVR--------
: * .. : .
Mb2078c|M.bovis_AF2122/97 GPTDALPRCRQTVHRGAVIYG----
Rv2052c|M.tuberculosis_H37Rv GPTDALPRCRQTVHRGAVIYG----
Mflv_0443|M.gilvum_PYR-GCK ----------ATVIAGRVVYER---
Mvan_0224|M.vanbaalenii_PYR-1 ----------ATVIGGEVVYQRG--
MSMEG_0263|M.smegmatis_MC2_155 ----------ATIIGGSVVFSR---
MMAR_0459|M.marinum_M ----------ATIIGGEVAYAA---
MUL_1109|M.ulcerans_Agy99 ----------ATIIGGEVAYAA---
MAV_4955|M.avium_104 ----------ATIIGGELVYFAM--
TH_0643|M.thermoresistible__bu ----------ATIVGGKPVYQKPV-
MAB_1868c|M.abscessus_ATCC_199 ----------ATYLAGRQTYAAPVG
* * :