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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_0601 | - | - | 100% (317) | fructokinase |
M. thermoresistible (build 8) | TH_1517 | rbsK | 3e-07 | 30.77% (156) | RIBOKINASE RBSK |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2462 | rbsK | 2e-11 | 26.95% (308) | ribokinase RBSK |
M. gilvum PYR-GCK | Mflv_1827 | - | 1e-116 | 69.51% (305) | ribokinase-like domain-containing protein |
M. tuberculosis H37Rv | Rv2436 | rbsK | 2e-11 | 27.27% (308) | ribokinase RBSK |
M. leprae Br4923 | MLBr_02091 | - | 6e-08 | 48.28% (58) | hypothetical protein MLBr_02091 |
M. abscessus ATCC 19977 | MAB_0359 | - | 3e-33 | 35.86% (304) | putative fructokinase |
M. marinum M | MMAR_4574 | pfkB | 1e-107 | 64.77% (298) | fructokinase, PfkB |
M. avium 104 | MAV_1051 | - | 1e-108 | 65.23% (302) | kinase, PfkB family protein |
M. smegmatis MC2 155 | MSMEG_5577 | - | 1e-130 | 74.68% (308) | fructokinase |
M. ulcerans Agy99 | MUL_4435 | pfkB | 1e-104 | 63.42% (298) | fructokinase, PfkB |
M. vanbaalenii PYR-1 | Mvan_4916 | - | 1e-124 | 73.44% (305) | ribokinase-like domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment TH_0601|M.thermoresistible__bu -----------MTARALVIGEALIDVVERDGRVLG-----------EHVG MSMEG_5577|M.smegmatis_MC2_155 ------------MSRALVIGEALIDIVEREGQVVG-----------EHVG Mflv_1827|M.gilvum_PYR-GCK -------------MRALVIGEALIDIVERGDEVT------------EHVG Mvan_4916|M.vanbaalenii_PYR-1 -------------MRALVIGEALIDIVERDGGVT------------EHVG MMAR_4574|M.marinum_M ------------MARGLVIGEALIDIVDGP--DPA-----------EYVG MUL_4435|M.ulcerans_Agy99 ------------MARGLVIGEALIDIVDGP--DPA-----------EYVG MAV_1051|M.avium_104 ------------MTRGLVIGESLIDIVED-----A-----------EYVG MLBr_02091|M.leprae_Br4923 -------------------------------------------------- MAB_0359|M.abscessus_ATCC_1997 ---------MADGGGILVCGETLVDLVPVAGGLRR-----------PVPG Mb2462|M.bovis_AF2122/97 MANASETNVGPMAPRVCVVGSVNMDLTFVVDALPRPGETVLAASLTRTPG Rv2436|M.tuberculosis_H37Rv MANASETNVGPMAPRVCVVGSVNMDLTFVVDALPRPGETVLAASLTRTPG TH_0601|M.thermoresistible__bu GSPLNVAVGLARLGRDVDFLTHIADDARGRRIADHLADSGVQLVPGSRTA MSMEG_5577|M.smegmatis_MC2_155 GSPLNVAVGLGRLGRDVDFLTHIADDPRGRRIVDYLKASGVQLVPGSTSA Mflv_1827|M.gilvum_PYR-GCK GSPLNVAVGLARLGRDVDFLTHIGTDDRGRRIAEYVESSGVHLVPGSTAA Mvan_4916|M.vanbaalenii_PYR-1 GSPLNVAVGLARLGRDVDFLTHIGTDARGQRITDFVESSGAQLVPGSRSA MMAR_4574|M.marinum_M GSPLNVAVGLARLGRDVDLLTHIGRDARGRRIAEYIESSGVQLVSGSQTA MUL_4435|M.ulcerans_Agy99 GSPLNVAVGPARLGRDVDLLTHIGRDARGRRIAEYIESSGVQLVSGSQTA MAV_1051|M.avium_104 GSPLNVAVGLGRLGRDVDFLTYLADDDHGRRIAAYLKDAGVQLVSESRAA MLBr_02091|M.leprae_Br4923 -------------------------------------------------- MAB_0359|M.abscessus_ATCC_1997 GGPYNTAIAAAKLGAPTALLTHVSHDAFGSRCVQDLAAAGVDESLVMRHD Mb2462|M.bovis_AF2122/97 GKGANQAVAAARAGAQVQFSGAFGDDPAAAQLRAHLRANAVGLDRTVTVP Rv2436|M.tuberculosis_H37Rv GKGANQAVAAARAGAQVQFSGAFGDDPAAAQLRAHLRANAVGLDRTVTVP TH_0601|M.thermoresistible__bu KRTPTAVARLDATGAADYTFDIDWQ------LSGTPEVAPPVVAHTGSIA MSMEG_5577|M.smegmatis_MC2_155 KKTPTAQVRLDAAGSATYEFDIDWQ------LAGTAEVAPPIVAHSGSIA Mflv_1827|M.gilvum_PYR-GCK PRTATARAKLDAAGSASYSFNIEWA------LTGTPEVAPPLVVHTGSIA Mvan_4916|M.vanbaalenii_PYR-1 ARTATARAVLDATGSATYSFDIDWQ------LSGTPEVAPPLVVHTGSIA MMAR_4574|M.marinum_M DRTPTATARIGPDGSATYAFDLEWQ------IPDTPPVAPPLLVHTGSIA MUL_4435|M.ulcerans_Agy99 DRTPTATARIGPDGSATYAFDLEWQ------IPDTPPVAPPLLVHTGSIA MAV_1051|M.avium_104 ERTATARSTIAADGSADYEFDLDWR------LSGIPPVAPPLFVHTGSIA MLBr_02091|M.leprae_Br4923 -------------------------------------------------- MAB_0359|M.abscessus_ATCC_1997 VPTTLAVADVDEHGAARYLFYWQGTSNDVAIQSFPDPVRTPVAIWAGSIA Mb2462|M.bovis_AF2122/97 GPSGTAIIVVDASAENTVLVAPGAN-------AHLTPVPSAVANCDVLLT Rv2436|M.tuberculosis_H37Rv GPSGTAIIVVDASAENTVLVAPGAN-------AHLTPVPSAVANCDVLLT TH_0601|M.thermoresistible__bu AVLEPGCRAAAALIDTYHVSATTTFDPNVRPALITDDTGARARIDRFIER MSMEG_5577|M.smegmatis_MC2_155 TVLEPGCRAAAALLDAYHLSATITFDPNVRPALISDGETARRRIERLVER Mflv_1827|M.gilvum_PYR-GCK AVHEPGCLATKALIDAYHLSATFTFDPNIRAALITDADAARSRIDRLLEQ Mvan_4916|M.vanbaalenii_PYR-1 AVLEPGCLATTALVDTYHLSATFTFDPNVRPALITDPDAARSRIDRLLER MMAR_4574|M.marinum_M AAREPGCLAVAALLDAYRAAATVSFDPNVRPSLSADPDLTRERIQRLVER MUL_4435|M.ulcerans_Agy99 AAREPGCLAVAALLDAYRAAATVSFDPNVRPSLRADPDLTRERIQRLVER MAV_1051|M.avium_104 AVRDPGCLAVAALIDTYRVSATVTFDPNVRPSLIADRELAVSRIEHLVER MLBr_02091|M.leprae_Br4923 -----------------------------------------------MNR MAB_0359|M.abscessus_ATCC_1997 SVLWRERDELRAWIARHYADIPLTFDVNVRPALISHRQTYAARIVPWLSV Mb2462|M.bovis_AF2122/97 QLEIPVATALAAARAAQSADAVVMVN-------ASPAGQDRSSLQDLAAI Rv2436|M.tuberculosis_H37Rv QLEIPVATALAAARAAQSADAVVMVN-------ASPAGQDRSSLQDLAAI TH_0601|M.thermoresistible__bu CDVVKASDEDLQWLEPGRSPEQVAQTWLRMGP--SLVAVTMGDRGAYAVC MSMEG_5577|M.smegmatis_MC2_155 ADVVKISDEDLRWLDSRRSPEQIAKTWLSMGP--SIVAVTAGGEGSFAVC Mflv_1827|M.gilvum_PYR-GCK ADVVKASHEDLHWIDPTRTPEQVAAAWLALGP--AIVVVTFGADGALAMC Mvan_4916|M.vanbaalenii_PYR-1 ADVVKASSEDLHWIDPTRNPEQVATAWLALGP--SIVVVTFGAEGSVAMC MMAR_4574|M.marinum_M SDIIKASAEDLHWIDPTQPPEQTARAWLACGP--AIVALTLGDQGAVAFC MUL_4435|M.ulcerans_Agy99 SDIIKASAEDLHWIDPTQPPEQTARAWLACGP--AIVALTFGDQSAVAFC MAV_1051|M.avium_104 SDIVKVSAEDLHWIDPDRSPEQLAQTWLGLGP--AVVAVTMADRGAVGYC MLBr_02091|M.leprae_Br4923 PDLVDIWTGDR-----------------------------CGEQGALALC MAB_0359|M.abscessus_ATCC_1997 ARVARASTDDLEFLYPGVSVRDAVNAWLDAYPRIEIAVITCGAAGSLAFR Mb2462|M.bovis_AF2122/97 ADVVIAN-------------EHEANDWPSPPT---HFVITLGVRGARYVG Rv2436|M.tuberculosis_H37Rv ADVVIAN-------------EHEANDWPSPPT---HFVITLGVRGARYVG : . .: TH_0601|M.thermoresistible__bu AAG--EVRVPARPVEVVDTVGAGDAFMAGLIDALWSLQLLGAERRRQLAG MSMEG_5577|M.smegmatis_MC2_155 GAG--MVRVPARTVEVIDTVGAGDAFMTGLLDALWSLDLLGADRRRNLAH Mflv_1827|M.gilvum_PYR-GCK AAG--SVRVPAGNVHVVDTVGAGDAFMTGLIDALWSADLLGADRRHHLAR Mvan_4916|M.vanbaalenii_PYR-1 ADG--TVRVPAGNVDVVDTVGAGDAFMTGLIDALWSMDLLGAGRRARLAG MMAR_4574|M.marinum_M AAG--PASVPAQPVRVVDTVGAGDAFMAGLLDTLWEQGLLGADRRTELRK MUL_4435|M.ulcerans_Agy99 AAG--PASMPAQPVRVVDTVGAGDAFMAGLLDTLWEQGLLDADRRTELRK MAV_1051|M.avium_104 AAG--TARVPTRAVRVVDTVGAGDSFMAGLLDALWEAGLLGGDRRGALRD MLBr_02091|M.leprae_Br4923 LAG--KARVDIRNFRVVDTVCTSDEFMVRLLDGLWGYGL----------- MAB_0359|M.abscessus_ATCC_1997 RGEPSPLRIAAHKVSVVDTVGAGDTYTGAFLDGFYRHRLD---------- Mb2462|M.bovis_AF2122/97 ADG--VFEVPAPTVTPVDTAGAGDVFAG-VLAANWPRNPGSPAER----- Rv2436|M.tuberculosis_H37Rv ADG--VFEVPAPTVTPVDTAGAGDVFAG-VLAANWPRNPGSPAER----- : . :**. :.* : .: : TH_0601|M.thermoresistible__bu IAVEALQRVVETAALSSALTVARAGADLPDRATRDAAAAATERETGTY MSMEG_5577|M.smegmatis_MC2_155 ISTDALEHVLSTAALTSALTVAKAGADLPD---RDALRAAQQ------ Mflv_1827|M.gilvum_PYR-GCK IDVDALTTAVRAATLTSALTVAKSGADLPDRVERDTAPASDILS---- Mvan_4916|M.vanbaalenii_PYR-1 IGTDALTTAVRAATLTAALTVTRPGADLPDRVTRDAATASDILG---- MMAR_4574|M.marinum_M IGVSALTSALEVAALTSALTVARAGADLPY---RADLRQSR------- MUL_4435|M.ulcerans_Agy99 IGVSALTSALEVAALTSALTVARAGADLPY---RADLRQSR------- MAV_1051|M.avium_104 IGIDTLTSALDAASLSSALTIARAGADLPD---RAAVQAALRR----- MLBr_02091|M.leprae_Br4923 ------------------------------------------------ MAB_0359|M.abscessus_ATCC_1997 -----LPEALRRAAVAAAITCTRPGAQPPDATELANELRRVTS----- Mb2462|M.bovis_AF2122/97 --LRALRRACAAGVLATLVSGAGDCAPAAAAIDAALRANRHNGS---- Rv2436|M.tuberculosis_H37Rv --LRALRRACAAGALATLVSGVGDCAPAAAAIDAALRANRHNGS----