For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VADGGGILVCGETLVDLVPVAGGLRRPVPGGGPYNTAIAAAKLGAPTALLTHVSHDAFGSRCVQDLAAAG VDESLVMRHDVPTTLAVADVDEHGAARYLFYWQGTSNDVAIQSFPDPVRTPVAIWAGSIASVLWRERDEL RAWIARHYADIPLTFDVNVRPALISHRQTYAARIVPWLSVARVARASTDDLEFLYPGVSVRDAVNAWLDA YPRIEIAVITCGAAGSLAFRRGEPSPLRIAAHKVSVVDTVGAGDTYTGAFLDGFYRHRLDLPEALRRAAV AAAITCTRPGAQPPDATELANELRRVTS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0359 | - | - | 100% (308) | putative fructokinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_1827 | - | 7e-29 | 32.91% (313) | ribokinase-like domain-containing protein |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_4574 | pfkB | 4e-27 | 31.19% (311) | fructokinase, PfkB |
| M. avium 104 | MAV_1051 | - | 1e-26 | 30.25% (314) | kinase, PfkB family protein |
| M. smegmatis MC2 155 | MSMEG_5577 | - | 8e-29 | 33.23% (313) | fructokinase |
| M. thermoresistible (build 8) | TH_0601 | - | 3e-33 | 35.86% (304) | fructokinase |
| M. ulcerans Agy99 | MUL_4435 | pfkB | 3e-26 | 30.87% (311) | fructokinase, PfkB |
| M. vanbaalenii PYR-1 | Mvan_4916 | - | 3e-34 | 35.64% (303) | ribokinase-like domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5577|M.smegmatis_MC2_155 ---MSRALVIGEALIDIVEREGQVVGEHVGGSPLNVAVGLGRLGRDVDFL
TH_0601|M.thermoresistible__bu --MTARALVIGEALIDVVERDGRVLGEHVGGSPLNVAVGLARLGRDVDFL
Mflv_1827|M.gilvum_PYR-GCK ----MRALVIGEALIDIVERGDEVT-EHVGGSPLNVAVGLARLGRDVDFL
Mvan_4916|M.vanbaalenii_PYR-1 ----MRALVIGEALIDIVERDGGVT-EHVGGSPLNVAVGLARLGRDVDFL
MMAR_4574|M.marinum_M ---MARGLVIGEALIDIVDGP--DPAEYVGGSPLNVAVGLARLGRDVDLL
MUL_4435|M.ulcerans_Agy99 ---MARGLVIGEALIDIVDGP--DPAEYVGGSPLNVAVGPARLGRDVDLL
MAV_1051|M.avium_104 ---MTRGLVIGESLIDIVED-----AEYVGGSPLNVAVGLGRLGRDVDFL
MAB_0359|M.abscessus_ATCC_1997 MADGGGILVCGETLVDLVPVAGGLRRPVPGGGPYNTAIAAAKLGAPTALL
** **:*:*:* **.* *.*:. .:** . :*
MSMEG_5577|M.smegmatis_MC2_155 THIADDPRGRRIVDYLKASGVQLVPGSTSAKKTPTAQVRLDAAGSATYEF
TH_0601|M.thermoresistible__bu THIADDARGRRIADHLADSGVQLVPGSRTAKRTPTAVARLDATGAADYTF
Mflv_1827|M.gilvum_PYR-GCK THIGTDDRGRRIAEYVESSGVHLVPGSTAAPRTATARAKLDAAGSASYSF
Mvan_4916|M.vanbaalenii_PYR-1 THIGTDARGQRITDFVESSGAQLVPGSRSAARTATARAVLDATGSATYSF
MMAR_4574|M.marinum_M THIGRDARGRRIAEYIESSGVQLVSGSQTADRTPTATARIGPDGSATYAF
MUL_4435|M.ulcerans_Agy99 THIGRDARGRRIAEYIESSGVQLVSGSQTADRTPTATARIGPDGSATYAF
MAV_1051|M.avium_104 TYLADDDHGRRIAAYLKDAGVQLVSESRAAERTATARSTIAADGSADYEF
MAB_0359|M.abscessus_ATCC_1997 THVSHDAFGSRCVQDLAAAGVDESLVMRHDVPTTLAVADVDEHGAARYLF
*::. * * * . : :*.. *. * : *:* * *
MSMEG_5577|M.smegmatis_MC2_155 DIDWQLAGTA------EVAPPIVAHSGSIATVLEPGCRAAAALLDAYHLS
TH_0601|M.thermoresistible__bu DIDWQLSGTP------EVAPPVVAHTGSIAAVLEPGCRAAAALIDTYHVS
Mflv_1827|M.gilvum_PYR-GCK NIEWALTGTP------EVAPPLVVHTGSIAAVHEPGCLATKALIDAYHLS
Mvan_4916|M.vanbaalenii_PYR-1 DIDWQLSGTP------EVAPPLVVHTGSIAAVLEPGCLATTALVDTYHLS
MMAR_4574|M.marinum_M DLEWQIPDTP------PVAPPLLVHTGSIAAAREPGCLAVAALLDAYRAA
MUL_4435|M.ulcerans_Agy99 DLEWQIPDTP------PVAPPLLVHTGSIAAAREPGCLAVAALLDAYRAA
MAV_1051|M.avium_104 DLDWRLSGIP------PVAPPLFVHTGSIAAVRDPGCLAVAALIDTYRVS
MAB_0359|M.abscessus_ATCC_1997 YWQGTSNDVAIQSFPDPVRTPVAIWAGSIASVLWRERDELRAWIARHYAD
: . . * .*: :****:. * : :
MSMEG_5577|M.smegmatis_MC2_155 ATITFDPNVRPALISDGETARRRIERLVERADVVKISDEDLRWLDSRRSP
TH_0601|M.thermoresistible__bu ATTTFDPNVRPALITDDTGARARIDRFIERCDVVKASDEDLQWLEPGRSP
Mflv_1827|M.gilvum_PYR-GCK ATFTFDPNIRAALITDADAARSRIDRLLEQADVVKASHEDLHWIDPTRTP
Mvan_4916|M.vanbaalenii_PYR-1 ATFTFDPNVRPALITDPDAARSRIDRLLERADVVKASSEDLHWIDPTRNP
MMAR_4574|M.marinum_M ATVSFDPNVRPSLSADPDLTRERIQRLVERSDIIKASAEDLHWIDPTQPP
MUL_4435|M.ulcerans_Agy99 ATVSFDPNVRPSLRADPDLTRERIQRLVERSDIIKASAEDLHWIDPTQPP
MAV_1051|M.avium_104 ATVTFDPNVRPSLIADRELAVSRIEHLVERSDIVKVSAEDLHWIDPDRSP
MAB_0359|M.abscessus_ATCC_1997 IPLTFDVNVRPALISHRQTYAARIVPWLSVARVARASTDDLEFLYPGVSV
. :** *:*.:* :. ** :. . : : * :**.:: .
MSMEG_5577|M.smegmatis_MC2_155 EQIAKTWLSMGP--SIVAVTAGGEGSFAVCGAG--MVRVPARTVEVIDTV
TH_0601|M.thermoresistible__bu EQVAQTWLRMGP--SLVAVTMGDRGAYAVCAAG--EVRVPARPVEVVDTV
Mflv_1827|M.gilvum_PYR-GCK EQVAAAWLALGP--AIVVVTFGADGALAMCAAG--SVRVPAGNVHVVDTV
Mvan_4916|M.vanbaalenii_PYR-1 EQVATAWLALGP--SIVVVTFGAEGSVAMCADG--TVRVPAGNVDVVDTV
MMAR_4574|M.marinum_M EQTARAWLACGP--AIVALTLGDQGAVAFCAAG--PASVPAQPVRVVDTV
MUL_4435|M.ulcerans_Agy99 EQTARAWLACGP--AIVALTFGDQSAVAFCAAG--PASMPAQPVRVVDTV
MAV_1051|M.avium_104 EQLAQTWLGLGP--AVVAVTMADRGAVGYCAAG--TARVPTRAVRVVDTV
MAB_0359|M.abscessus_ATCC_1997 RDAVNAWLDAYPRIEIAVITCGAAGSLAFRRGEPSPLRIAAHKVSVVDTV
.: . :** * :..:* . .: . :.: * *:***
MSMEG_5577|M.smegmatis_MC2_155 GAGDAFMTGLLDALWSLDLLGADRRRNLAHISTDALEHVLSTAALTSALT
TH_0601|M.thermoresistible__bu GAGDAFMAGLIDALWSLQLLGAERRRQLAGIAVEALQRVVETAALSSALT
Mflv_1827|M.gilvum_PYR-GCK GAGDAFMTGLIDALWSADLLGADRRHHLARIDVDALTTAVRAATLTSALT
Mvan_4916|M.vanbaalenii_PYR-1 GAGDAFMTGLIDALWSMDLLGAGRRARLAGIGTDALTTAVRAATLTAALT
MMAR_4574|M.marinum_M GAGDAFMAGLLDTLWEQGLLGADRRTELRKIGVSALTSALEVAALTSALT
MUL_4435|M.ulcerans_Agy99 GAGDAFMAGLLDTLWEQGLLDADRRTELRKIGVSALTSALEVAALTSALT
MAV_1051|M.avium_104 GAGDSFMAGLLDALWEAGLLGGDRRGALRDIGIDTLTSALDAASLSSALT
MAB_0359|M.abscessus_ATCC_1997 GAGDTYTGAFLDGFYRHRLD---------------LPEALRRAAVAAAIT
****:: .::* :: * * .: *::::*:*
MSMEG_5577|M.smegmatis_MC2_155 VAKAGADLPD---RDALRAAQQ------
TH_0601|M.thermoresistible__bu VARAGADLPDRATRDAAAAATERETGTY
Mflv_1827|M.gilvum_PYR-GCK VAKSGADLPDRVERDTAPASDILS----
Mvan_4916|M.vanbaalenii_PYR-1 VTRPGADLPDRVTRDAATASDILG----
MMAR_4574|M.marinum_M VARAGADLPY---RADLRQSR-------
MUL_4435|M.ulcerans_Agy99 VARAGADLPY---RADLRQSR-------
MAV_1051|M.avium_104 IARAGADLPD---RAAVQAALRR-----
MAB_0359|M.abscessus_ATCC_1997 CTRPGAQPPDATELANELRRVTS-----
::.**: *