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M. thermoresistible (build 8) TH_0584 (moxR2)

annotation: PROBABLE METHANOL DEHYDROGENASE TRANSCRIPTIONAL REGULATORY PROTEIN MOXR2
coordinates: 1245765 - 1246730
length: 322

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0584moxR2-100% (322)PROBABLE METHANOL DEHYDROGENASE TRANSCRIPTIONAL REGULATORY PROTEIN MOXR2
M. thermoresistible (build 8)TH_1715moxR21e-8251.15% (305) PROBABLE METHANOL DEHYDROGENASE TRANSCRIPTIONAL REGULATORY
M. thermoresistible (build 8)TH_3229-2e-6441.85% (313) PUTATIVE ATPase associated with various cellular activities,

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3189cmoxR31e-14078.30% (318) methanol dehydrogenase transcriptional regulatory protein
M. gilvum PYR-GCKMflv_0476-1e-13777.32% (313) ATPase
M. tuberculosis H37RvRv3164cmoxR31e-14178.30% (318) methanol dehydrogenase transcriptional regulatory protein
M. leprae Br4923MLBr_01810moxR3e-6441.72% (314) MoxR homolog
M. abscessus ATCC 19977MAB_1909c-1e-13374.45% (317) methanol dehydrogenase transcriptional regulatory protein MoxR3
M. marinum MMMAR_1399moxR31e-14078.10% (315) methanol dehydrogenase transcriptional regulatory protein
M. avium 104MAV_4052-1e-13480.60% (299) ATPase family protein associated with various cellular
M. smegmatis MC2 155MSMEG_3867-1e-9777.29% (229) ATPase family protein associated with various cellular
M. ulcerans Agy99MUL_2477moxR31e-13977.78% (315) methanol dehydrogenase transcriptional regulatory protein
M. vanbaalenii PYR-1Mvan_0180-1e-13879.23% (313) ATPase

CLUSTAL 2.0.9 multiple sequence alignment


Mb3189c|M.bovis_AF2122/97           -------------------------------MIMPAATTTAHCEAVLDEI
Rv3164c|M.tuberculosis_H37Rv        -------------------------------MIMPAATTTAHCEAVLDEI
MMAR_1399|M.marinum_M               -------------------------------MTMPAALTTAACEAVIDEI
MUL_2477|M.ulcerans_Agy99           -------------------------------MTMPAALTTAACEAVIDEI
MAV_4052|M.avium_104                --------------------------------------------------
Mflv_0476|M.gilvum_PYR-GCK          --------------------------------MSTPALTTARCEAVLDEI
Mvan_0180|M.vanbaalenii_PYR-1       --------------------------------MTTPALTTARCEAVLDEI
TH_0584|M.thermoresistible__bu      --------------------------------MMPATTATAHCHAVLDEV
MAB_1909c|M.abscessus_ATCC_199      ------------------------------MTTVPISIATRHADAVLTEI
MSMEG_3867|M.smegmatis_MC2_155      ----------------------------MTSQANVDVATAAAARSVLDEI
MLBr_01810|M.leprae_Br4923          MTSAGGLPVGADGCSGPGGQSGPRAHEAPPGGADGLVAEVHTLERAIFEV
                                                                                      

Mb3189c|M.bovis_AF2122/97           GRVVVGKRSALTLILTAVLARGHVLIEDLPGLGKTLIARSFAAALGLDFT
Rv3164c|M.tuberculosis_H37Rv        ERVVVGKRSALTLILTAVLARGHVLIEDLPGLGKTLIARSFAAALGLDFT
MMAR_1399|M.marinum_M               ERVVVGKRAALTLILTAVLARGHVLIEDLPGLGKTLIARSFAAALGLEFK
MUL_2477|M.ulcerans_Agy99           ERVVVGKRAALTLILTAVLARGHVLIEDLPGLGKTLIARSFAAALGLEFK
MAV_4052|M.avium_104                --MVVGKRNALRLILTAVLARGHILIEDLPGLGKTLIARSFAAALGLQFT
Mflv_0476|M.gilvum_PYR-GCK          GRAVVGKRGALNLILITVLARGHVLVEDLPGLGKTLIAKSFAAALGLEFT
Mvan_0180|M.vanbaalenii_PYR-1       GRAVVGKRNALNLILITVLARGHVLVEDLPGLGKTLIAKSFAAALGLEFT
TH_0584|M.thermoresistible__bu      QRAVVGNRAALELILLTVLARGHILVEDLPGLGKTLIARTFSAALGLRFT
MAB_1909c|M.abscessus_ATCC_199      ERVVVGKRDALQLILLTILARGHVLIEDLPGLGKTLIARSFASALGLDFT
MSMEG_3867|M.smegmatis_MC2_155      EKAVVGKRDALTLILTTLLARGHVLIEDLPGLGKTLIARSFAAALGLKFT
MLBr_01810|M.leprae_Br4923          KRVIVGQDQLVERMLVGLLSKGHVLLEGVPGVAKTLAVETFARVVGGTFA
                                       :**:   :  :*  :*::**:*:*.:**:.*** ..:*: .:*  * 

Mb3189c|M.bovis_AF2122/97           RVQFTPDLLPADLLGSTIYDMQSGRFEFRAGPIFTNLLLADEINRTPPKT
Rv3164c|M.tuberculosis_H37Rv        RVQFTPDLLPADLLGSTIYDMQSGRFEFRAGPIFTNLLLADEINRTPPKT
MMAR_1399|M.marinum_M               RVQFTPDLLPADLLGSTIYDMQSGRFEFRAGPIFTNLLMADEINRTPPKT
MUL_2477|M.ulcerans_Agy99           RVQFTPDLLPADLLGSTIYDMQSGRFEFRAGPIFTNLLMADEINRTPPKT
MAV_4052|M.avium_104                RVQFTPDLLPADLLGSTIYDMQSGRFAFRAGPIFTNLLLADEINRTPPKT
Mflv_0476|M.gilvum_PYR-GCK          RVQFTPDLLPADLLGSTIYDMQSGRFEFRRGPVFTNLLLGDEINRTPPKT
Mvan_0180|M.vanbaalenii_PYR-1       RVQFTPDLLPADLLGSTIYDMQSGRFEFRRGPIFTNLLLGDEINRTPPKT
TH_0584|M.thermoresistible__bu      RVQFTPDLLPADLLGTTIYDMRSGGFEFRPGPIFTNLLLADEINRTPPKT
MAB_1909c|M.abscessus_ATCC_199      RVQFTPDLLPADLLGSTIYDMSSGSFEFRTGPIFTNLLLADEINRTPPKT
MSMEG_3867|M.smegmatis_MC2_155      RVQFTPDLLPADLLGSTVYDMQSGRFEFRPGPIFTNLLLADEINRTPPKT
MLBr_01810|M.leprae_Br4923          RIQFTPDLVPTDIIGTRIYRQGKEEFDTELGPVVVNFLLADEINRAPAKV
                                    *:******:*:*::*: :*   .  *  . **:..*:*:.*****:*.*.

Mb3189c|M.bovis_AF2122/97           QAALLEAMAEGQVSIDGQTHKLAMPFIVLATDNPIEYEGTYPLPEAQLDR
Rv3164c|M.tuberculosis_H37Rv        QAALLEAMAEGQVSIDGQTHKLAMPFIVLATDNPIEYEGTYPLPEAQLDR
MMAR_1399|M.marinum_M               QAALLEAMAEGQVSIDGQTHKLPMPFIVLATDNPIEYEGTYPLPEAQLDR
MUL_2477|M.ulcerans_Agy99           QAALLEAMAEGQVSIDGQTHKLPVPFIVLATDNPIEHEGTYPLPEAQLDR
MAV_4052|M.avium_104                QAALLEAMAEGQVSIDGETHRLPKPFIVLATDNPIEYEGTYPLPEAQLDR
Mflv_0476|M.gilvum_PYR-GCK          QAALLEAMAERQVSIDGATHRLPEPFLVLATDNPIEYEGTYPLPEAQLDR
Mvan_0180|M.vanbaalenii_PYR-1       QAALLEAMAEGQVSVDGVTHRLPQPFLVLATDNPIEYEGTYPLPEAQLDR
TH_0584|M.thermoresistible__bu      QAALLEAMAETQVTIDGVSHRLPAPFVVLATDNPIEYEGTYPLPEAQLDR
MAB_1909c|M.abscessus_ATCC_199      QSALLEAMAEGQVSLDGQTRQLPSPFVVLATDNPIEYEGTYPLPEAQLDR
MSMEG_3867|M.smegmatis_MC2_155      QAALLEAMAEGQVSIDGQTHRLPAPFIVLATDNPIEYEGTYPLPEAQLDR
MLBr_01810|M.leprae_Br4923          QSALLEVMQERHVSIGGKTFPLPNPFLVMATQNPIEHEGVYLLPEAQRDR
                                    *:****.* * :*::.* :  *. **:*:**:****:**.* ***** **

Mb3189c|M.bovis_AF2122/97           FAIRLELRYLSERDETSMLRRRLERGSADPTVNQVVDCHDLLAMRESVEQ
Rv3164c|M.tuberculosis_H37Rv        FAIRLELRYLSERDETSMLRRRLERGSADPTVNQVVDCHDLLAMRESVEQ
MMAR_1399|M.marinum_M               FAIRLELRYLSEQDETAMLRRRLERGSAEATVNQVVDLHDLLAMRESVEQ
MUL_2477|M.ulcerans_Agy99           FAIRLELRYLSEQDETAMLRRRLERGSAEATVNQVVDLHDLLAMRESVEQ
MAV_4052|M.avium_104                FAIRLELRYLSERDETSMLRRRLERGSAEPAVNQVVDAHDLLAMRESVEQ
Mflv_0476|M.gilvum_PYR-GCK          FAIRLELKYLSESEEATMLRRRLDRGSAPATVNQIVDAQDLLHMQESVEQ
Mvan_0180|M.vanbaalenii_PYR-1       FAIRLELKYLNESEEVTMLRRRLERGSTAPTVQQVVDSHDLLAMQESVEN
TH_0584|M.thermoresistible__bu      FAVRLELGYLSAPEEVSMLRRRIERGADDVVITEVVDADALIAMREAVEA
MAB_1909c|M.abscessus_ATCC_199      FAVRLQLGYLAEDLEIEMLQRRLSRGSTLPTVSQVIAADDLIAMREAVEA
MSMEG_3867|M.smegmatis_MC2_155      FSVRLELKYLSEQDETAMLRRRLDRGSAEAGVAEVVDGPRFLAMREAVEQ
MLBr_01810|M.leprae_Br4923          FLFKINVGYPSPEEEREIIYR---MGVTPPVPKQILNAGDLLRLQEISAN
                                    * .:::: *     *  :: *    *       :::    :: ::*    

Mb3189c|M.bovis_AF2122/97           VTVHEDVLHYVVSLAN---------------------ATR----------
Rv3164c|M.tuberculosis_H37Rv        VTVHEDVLHYVVSLAN---------------------ATR----------
MMAR_1399|M.marinum_M               VTVHDDVLHYVVSLAT---------------------ATR----------
MUL_2477|M.ulcerans_Agy99           VTVHDDVLQYVVSLAT---------------------ATR----------
MAV_4052|M.avium_104                VTVHEDVLHYVVSLAN---------------------ATR----------
Mflv_0476|M.gilvum_PYR-GCK          VSVHDDVVQYVVSLAA---------------------ASR----------
Mvan_0180|M.vanbaalenii_PYR-1       VTVHDDVLQYIVSLAT---------------------ASR----------
TH_0584|M.thermoresistible__bu      VTVHDDVLDYVVALAT---------------------ATR----------
MAB_1909c|M.abscessus_ATCC_199      VSVHPDVLRYIVALAA---------------------ATR----------
MSMEG_3867|M.smegmatis_MC2_155      VSVHDDVLRYVVALRGRDAPPPAGCGRRQPPRRTRPRATREGQGLAARAG
MLBr_01810|M.leprae_Br4923          NFVHHALVDYVVRVVT---------------------ATR----------
                                      **  :: *:* :                       *:*          

Mb3189c|M.bovis_AF2122/97           ----------------------------HHP-------------------
Rv3164c|M.tuberculosis_H37Rv        ----------------------------HHP-------------------
MMAR_1399|M.marinum_M               ----------------------------NHP-------------------
MUL_2477|M.ulcerans_Agy99           ----------------------------NHP-------------------
MAV_4052|M.avium_104                ----------------------------HHP-------------------
Mflv_0476|M.gilvum_PYR-GCK          ----------------------------QHP-------------------
Mvan_0180|M.vanbaalenii_PYR-1       ----------------------------QHP-------------------
TH_0584|M.thermoresistible__bu      ----------------------------RHP-------------------
MAB_1909c|M.abscessus_ATCC_199      ----------------------------SHS-------------------
MSMEG_3867|M.smegmatis_MC2_155      LRHPRGRQDTRGRGDGAPHQPAPGDVGAQHPRCRRHERTAAPAPRAPCGQ
MLBr_01810|M.leprae_Br4923          -----------------------------HPEQLG---------------
                                                                 *.                   

Mb3189c|M.bovis_AF2122/97           --------------------------------------------------
Rv3164c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1399|M.marinum_M               --------------------------------------------------
MUL_2477|M.ulcerans_Agy99           --------------------------------------------------
MAV_4052|M.avium_104                --------------------------------------------------
Mflv_0476|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0180|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0584|M.thermoresistible__bu      --------------------------------------------------
MAB_1909c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_3867|M.smegmatis_MC2_155      PAMTVGVHVPLRWGASPLTKSVATAAAGAMLIAVLGFRWQLVIFASPLLG
MLBr_01810|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3189c|M.bovis_AF2122/97           ------------QVAVGASPR-----------------------------
Rv3164c|M.tuberculosis_H37Rv        ------------QVAVGASPR-----------------------------
MMAR_1399|M.marinum_M               ------------QVAVGASPR-----------------------------
MUL_2477|M.ulcerans_Agy99           ------------QVAVGASPR-----------------------------
MAV_4052|M.avium_104                ------------QVAVGASPR-----------------------------
Mflv_0476|M.gilvum_PYR-GCK          ------------QVAVGASPR-----------------------------
Mvan_0180|M.vanbaalenii_PYR-1       ------------QVAVGTSPR-----------------------------
TH_0584|M.thermoresistible__bu      ------------QVAVGASPR-----------------------------
MAB_1909c|M.abscessus_ATCC_199      ------------HVEVGASPR-----------------------------
MSMEG_3867|M.smegmatis_MC2_155      VLCSAYWQRPRVSVEVGAEPATVRCFENESAELSVRVSSSAGADARLRVD
MLBr_01810|M.leprae_Br4923          ------MNDVKTWISFGASPR-----------------------------
                                                 : .*:.*                              

Mb3189c|M.bovis_AF2122/97           --------------------------------------------------
Rv3164c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1399|M.marinum_M               --------------------------------------------------
MUL_2477|M.ulcerans_Agy99           --------------------------------------------------
MAV_4052|M.avium_104                --------------------------------------------------
Mflv_0476|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0180|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0584|M.thermoresistible__bu      --------------------------------------------------
MAB_1909c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_3867|M.smegmatis_MC2_155      SVEGLRLEPGDRAGPEQRVRANASRWGRYPLRAHVTVTAPGGLVTGTGTV
MLBr_01810|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3189c|M.bovis_AF2122/97           --AELDLVQLSR------ARALLLG-------------------RDYVIP
Rv3164c|M.tuberculosis_H37Rv        --AELDLVQLSR------ARALLLG-------------------RDYVIP
MMAR_1399|M.marinum_M               --AELDLVQLSR------ARALLLG-------------------RDYVIP
MUL_2477|M.ulcerans_Agy99           --AELDLVQLSR------ARALLLG-------------------RDYVIP
MAV_4052|M.avium_104                --AELDLVQLAR------ARALLLG-------------------RDYVIP
Mflv_0476|M.gilvum_PYR-GCK          --AELDLVQLAR------ARALLLG-------------------RDYVIP
Mvan_0180|M.vanbaalenii_PYR-1       --AELDLVQLAR------ARALLLG-------------------RDYVIP
TH_0584|M.thermoresistible__bu      --AELDLVQLAR------ARALLLN-------------------RDYVIP
MAB_1909c|M.abscessus_ATCC_199      --AELDLVQMSR------ARALLLG-------------------RDFVIP
MSMEG_3867|M.smegmatis_MC2_155      EAAELYVFPLAAPHLTPMPRAELPDRLGTHLTRHTGPGVEYADVRPYVPG
MLBr_01810|M.leprae_Br4923          --ASLGIIKASR------SLALVRG-------------------RDYVIP
                                      *.* :.  :       . * : .                   * :*  

Mb3189c|M.bovis_AF2122/97           EDVKELATAAVAHRITLRPEMWVRKIAG----------------------
Rv3164c|M.tuberculosis_H37Rv        EDVKELATAAVAHRITLRPEMWVRKIAG----------------------
MMAR_1399|M.marinum_M               EDVKALATASIAHRITLRPEMWVRKIQG----------------------
MUL_2477|M.ulcerans_Agy99           EDVKALATASIAHRITLRPEMWVRKIQG----------------------
MAV_4052|M.avium_104                EDVKALATAAVAHRITLRPEMWVRKIQG----------------------
Mflv_0476|M.gilvum_PYR-GCK          EDVKALAVPTMAHRISLRPEMWVRRVQG----------------------
Mvan_0180|M.vanbaalenii_PYR-1       EDVKALAVPALAHRISPRPEMWVRRVQG----------------------
TH_0584|M.thermoresistible__bu      EDVKTLAVPALAHRIMLRPEMWVRQIRS----------------------
MAB_1909c|M.abscessus_ATCC_199      EDVKALAVPAVAHRISLRPEMWVRRITG----------------------
MSMEG_3867|M.smegmatis_MC2_155      DHLRTVNWPVSARRGRLHVTERLTDRGGDVVVLIDTHDQAPGPATQATER
MLBr_01810|M.leprae_Br4923          QDVIEVIPDVLRHRLVLTYNALADEISP----------------------
                                    :.:  :      :*                                    

Mb3189c|M.bovis_AF2122/97           -----ADVVSELLR------------RLP---------------------
Rv3164c|M.tuberculosis_H37Rv        -----ADVVSELLR------------RLP---------------------
MMAR_1399|M.marinum_M               -----ADVIAELLR------------RLP---------------------
MUL_2477|M.ulcerans_Agy99           -----ADVIAELLR------------RLP---------------------
MAV_4052|M.avium_104                -----ADVIGELLH------------RLP---------------------
Mflv_0476|M.gilvum_PYR-GCK          -----ADVVEELLR------------RTP---------------------
Mvan_0180|M.vanbaalenii_PYR-1       -----ADVIEELLR------------RTP---------------------
TH_0584|M.thermoresistible__bu      -----GDVIGELLR------------RLP---------------------
MAB_1909c|M.abscessus_ATCC_199      -----AHVVDELLH------------RLP---------------------
MSMEG_3867|M.smegmatis_MC2_155      TARGAAQVVQSALRSGDRAGIVALGGRQPRWLGLDIGRRQFYRVLDAILG
MLBr_01810|M.leprae_Br4923          -----EIVINRVLQT----------VALPQVN------------------
                                           *:   *:              *                     

Mb3189c|M.bovis_AF2122/97           ------------VPRISGT-------------------------------
Rv3164c|M.tuberculosis_H37Rv        ------------VPRISGT-------------------------------
MMAR_1399|M.marinum_M               ------------VPRTNTGSR-----------------------------
MUL_2477|M.ulcerans_Agy99           ------------VPRTNAGSR-----------------------------
MAV_4052|M.avium_104                ------------VPRTGAGPGQTG--------------------------
Mflv_0476|M.gilvum_PYR-GCK          ------------VPRAR---------------------------------
Mvan_0180|M.vanbaalenii_PYR-1       ------------VPRARETQ------------------------------
TH_0584|M.thermoresistible__bu      ------------VPRTGGPPP-----------------------------
MAB_1909c|M.abscessus_ATCC_199      ------------VPRASG--------------------------------
MSMEG_3867|M.smegmatis_MC2_155      AGGGFETTTGTLAPRAAVPPGAIVVAFSTMLNTEFAFALIELAKHGHAVV
MLBr_01810|M.leprae_Br4923          -----------SFPQQGHSVPSVTQAAAAASGR-----------------
                                                 *:                                   

Mb3189c|M.bovis_AF2122/97           --------------------------------------------------
Rv3164c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1399|M.marinum_M               --------------------------------------------------
MUL_2477|M.ulcerans_Agy99           --------------------------------------------------
MAV_4052|M.avium_104                --------------------------------------------------
Mflv_0476|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0180|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0584|M.thermoresistible__bu      --------------------------------------------------
MAB_1909c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_3867|M.smegmatis_MC2_155      AVDILEGAPFDNPDGLDPLIPRLWALQRSAMYRDMSTIGIDVVHWRGDIP
MLBr_01810|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3189c|M.bovis_AF2122/97           -----------------
Rv3164c|M.tuberculosis_H37Rv        -----------------
MMAR_1399|M.marinum_M               -----------------
MUL_2477|M.ulcerans_Agy99           -----------------
MAV_4052|M.avium_104                -----------------
Mflv_0476|M.gilvum_PYR-GCK          -----------------
Mvan_0180|M.vanbaalenii_PYR-1       -----------------
TH_0584|M.thermoresistible__bu      -----------------
MAB_1909c|M.abscessus_ATCC_199      -----------------
MSMEG_3867|M.smegmatis_MC2_155      LQDVMRLIPDRHRRRTR
MLBr_01810|M.leprae_Br4923          -----------------