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M. thermoresistible (build 8) TH_0454 (-)

annotation: sensor-type histidine kinase PrrB
coordinates: 985385 - 986725
length: 447

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0454--100% (447)sensor-type histidine kinase PrrB
M. thermoresistible (build 8)TH_2428-2e-3432.15% (311) PUTATIVE integral membrane sensor signal transduction histidine
M. thermoresistible (build 8)TH_2452-2e-2227.69% (372) PUTATIVE putative sensor histidine kinase PhoR

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0926cprrB0.080.90% (445) two component sensor histidine kinase PRRB
M. gilvum PYR-GCKMflv_1743-0.078.03% (446) integral membrane sensor signal transduction histidine kinase
M. tuberculosis H37RvRv0902cprrB0.080.90% (445) two component sensor histidine kinase PRRB
M. leprae Br4923MLBr_02124-0.078.43% (445) sensor histidine kinase
M. abscessus ATCC 19977MAB_0955c-1e-13358.12% (437) sensor histidine kinase PrrB
M. marinum MMMAR_4634prrB0.080.90% (445) two-component sensor histidine kinase PrrB
M. avium 104MAV_1021-0.079.10% (445) sensor-type histidine kinase PrrB
M. smegmatis MC2 155MSMEG_5663-0.082.51% (446) sensor-type histidine kinase PrrB
M. ulcerans Agy99MUL_0249prrB0.080.67% (445) two component sensor histidine kinase PrrB
M. vanbaalenii PYR-1Mvan_5010-0.082.62% (443) integral membrane sensor signal transduction histidine kinase

CLUSTAL 2.0.9 multiple sequence alignment


Mb0926c|M.bovis_AF2122/97           ----------------------MNILSRIFARTP---SLRTRVVVATAIG
Rv0902c|M.tuberculosis_H37Rv        ----------------------MNILSRIFARTP---SLRTRVVVATAIG
MMAR_4634|M.marinum_M               -------------------MTVMNILSRIFARTP---SLRTRVVVATAIG
MUL_0249|M.ulcerans_Agy99           ----------------------MNILSRIFARTP---SLRTRVVVATAIG
MLBr_02124|M.leprae_Br4923          ----------------------MNILSRIFARTP---SLRTRVVVATAIG
MAV_1021|M.avium_104                ----------------------MKLLSRIVTRTP---SLRARVAVATAIG
TH_0454|M.thermoresistible__bu      ----------------------MNLVTRLFRRTP---SLRTRVAFATAIA
MSMEG_5663|M.smegmatis_MC2_155      ----------------------MSMLTRIFRRTP---SLRTRVAFATAIG
Mflv_1743|M.gilvum_PYR-GCK          ----------------------MSALSRFVRRTP---SLRQRVAFTSAIA
Mvan_5010|M.vanbaalenii_PYR-1       ----------------------MIALSRIFRRTP---SLRTRVAFATAIA
MAB_0955c|M.abscessus_ATCC_199      MSTSHENPPVMGRPSKHRSQRITDLSYRLLEKPMRIFSLRTLVAIA-ALG
                                                               *:. :.    ***  *..: *:.

Mb0926c|M.bovis_AF2122/97           AAIPVLIVGTVVWVGITNDRKERLDRRLDEAAGF-AIPFVPRGLDEIPRS
Rv0902c|M.tuberculosis_H37Rv        AAIPVLIVGTVVWVGITNDRKERLDRRLDEAAGF-AIPFVPRGLDEIPRS
MMAR_4634|M.marinum_M               AAIPVLIVGTVVWVGITNDRKERLDRRLDEAAGF-AIPFVPRGLDEIPRS
MUL_0249|M.ulcerans_Agy99           AAIPVLIVGTVVWVGITNDRKERLDRRLDEAAGF-AIPFVPRGLDEIPRS
MLBr_02124|M.leprae_Br4923          AAIPVLIVGTVVWVGITNDRKERLDRKLDEAAGF-AIPFVPRGLDEIPRS
MAV_1021|M.avium_104                TAIVVVIAGAVVWFGITSAWRERLDRRLDETAGF-AIPFLPRGLNEIPRS
TH_0454|M.thermoresistible__bu      AAIVVGIVGVVVWVGITNDRKERLDRRLDEAAGF-ALPFVPRGLEQIPPS
MSMEG_5663|M.smegmatis_MC2_155      AAIVVVIVGTIVWIGITNDRKERLDRRLDEAAGF-AIPFLPRGLDQIPRS
Mflv_1743|M.gilvum_PYR-GCK          GAIVVLIAGTVVWFGITDAWNERLDRRLDEAAGF-VIPFLPRGLDEIPPS
Mvan_5010|M.vanbaalenii_PYR-1       AAIVVGIVGTVVWVGITNDRQERLDRRLDEAAGF-AIPLLPRSLDEIPKS
MAB_0955c|M.abscessus_ATCC_199      VMVLVVTLGTWVWLGVEEDQYSQLDRRLDSVSSLGAVSNLLNSVISSDKK
                                      : *   *. **.*: .   .:***:**..:.: .:. : ..: .   .

Mb0926c|M.bovis_AF2122/97           PNDQD-ALITVR-RGNVIKSNSDITLPKLQDDYADTYVRGVRYRVRTVEI
Rv0902c|M.tuberculosis_H37Rv        PNDQD-ALITVR-RGNVIKSNSDITLPKLQDDYADTYVRGVRYRVRTVEI
MMAR_4634|M.marinum_M               PNDQD-ALITVR-RGDLVKSNSDITLPKLQKDYADTYIRGVRYRVRTVEI
MUL_0249|M.ulcerans_Agy99           PNDQD-ALITVR-RGDLVKSNSDITLPKLQEDYADTYIRGVRYRVRTVEI
MLBr_02124|M.leprae_Br4923          PNDQD-AIITVR-RGNLVKSNFDITLPKLTNDYADTYLRGVRYRVRTVEI
MAV_1021|M.avium_104                PKDQD-TVITVR-RDGQVKSNSDVTLPPMEEGYADTYINGVRYRVRTVEV
TH_0454|M.thermoresistible__bu      PNDQD-VVITVR-RGDEVRSNSEVVLPELDADYADTYIDGVRYRVRTVQT
MSMEG_5663|M.smegmatis_MC2_155      PNDQD-AVITVR-QTGAVTSNSTVVLPELPAGYADTYIDGVRWRVRTVEI
Mflv_1743|M.gilvum_PYR-GCK          PNDQD-VVITVRRDGGDAASNSTVVLPEMEPGYADTYLDGVRYRVRTVEL
Mvan_5010|M.vanbaalenii_PYR-1       PNGQD-ALITVR-TGGQVTSNSNVVLPELEPGYADTYVDGVRYRVRTVAL
MAB_0955c|M.abscessus_ATCC_199      LDTPDGLVLTARVAGLTKSIPTDTELPLLEPGYANTKINGVEYRVR--SF
                                     .  *  ::*.*             ** :  .**:* : **.:***    

Mb0926c|M.bovis_AF2122/97           PGPEPTSVAVGATYDATVAETNNLHRRVLLICTFAIGAAAVFAWLLAAFA
Rv0902c|M.tuberculosis_H37Rv        PGPEPTSVAVGATYDATVAETNNLHRRVLLICTFAIGAAAVFAWLLAAFA
MMAR_4634|M.marinum_M               PGPEPTSVAVGATYDATIAETNNLHRRVLLICTFAIGAATVFAWLLAVFA
MUL_0249|M.ulcerans_Agy99           PGPEPTSVAVGATYDATIAETNNLHRRVLLICTFAIGAATVFAWLLAVFA
MLBr_02124|M.leprae_Br4923          PAPEPTSIAVGATYDATVAETNNLHRRVLLICGFAIAAAAVFAWLLAAFA
MAV_1021|M.avium_104                RTPQPATVEVGATYDDTIAQTNNLHRRVILICALSIGAAAVFAWLLAAFA
TH_0454|M.thermoresistible__bu      PYPIRTTLAVGATYDDTIADTANLHRRVILICTLAIGAATIAGWLLAAFA
MSMEG_5663|M.smegmatis_MC2_155      PAPGPMWVAVGATYDATIADTNNLHRRVLVICVFAVGAATVLGWVLAAFA
Mflv_1743|M.gilvum_PYR-GCK          ATPQPMSVAVGATYDATIADINNLHRRVLIICTLAIGAATLGGWVLAAFA
Mvan_5010|M.vanbaalenii_PYR-1       STPEPMSVAVGATYDATIADTNNLHRRVLIICTLAVGAATFGGWLLAAFA
MAB_0955c|M.abscessus_ATCC_199      IAPGNIPVAVGAPVAETQRQIDRYHMRILAICGGVLIGTVIVGWVISLIV
                                      *    : ***.   *  :  . * *:: **   : .:.. .*::: :.

Mb0926c|M.bovis_AF2122/97           VRPFKQLAEQTRSIDAGDEAPRVEVHGASEAIEIAEAMRGMLQRIWNEQN
Rv0902c|M.tuberculosis_H37Rv        VRPFKQLAEQTRSIDAGDEAPRVEVHGASEAIEIAEAMRGMLQRIWNEQN
MMAR_4634|M.marinum_M               VRPFKQLAEQTRSIDAGDEAPRVEVHGASEAIEIAEAMRGMLQRIWNEQI
MUL_0249|M.ulcerans_Agy99           VRPFKQLAEQTRSIDAGDEAPRVEVHGASEAIEIAEGMRGMLQRIWNEQI
MLBr_02124|M.leprae_Br4923          VRPFKQLAQQTRSVDAGGEAPRVEVHGATEAVEIAEAMRGMLQRIWNEQN
MAV_1021|M.avium_104                VRPFKRLAQQARSIDA-DERPQVAVRGASEAVEIAEAMRGMLQRIWKEQD
TH_0454|M.thermoresistible__bu      VRPFKQLAAQARSIDAGDEVPDVEIRGATEAVEIADAVKGMLQRIWKEQD
MSMEG_5663|M.smegmatis_MC2_155      VRPLKRLAEQTREIEAGDEAPDVEVRGATEAVEIAEAVNGMLKRIWKEQD
Mflv_1743|M.gilvum_PYR-GCK          VRPFKQLARQTSAIDTGDEEPDIDVRGATEAVEIAEAINGLVQRVWEEQE
Mvan_5010|M.vanbaalenii_PYR-1       VRPFKRLAQQTRQIEAGGEAPDIDIRGATEAVEIADAIKGLVERVWEEQG
MAB_0955c|M.abscessus_ATCC_199      VSPFRLLAQQARLINAQSNPDDVNVRGVREAVEISEAVEGMLERINTEQE
                                    * *:: ** *:  ::: .:   : ::*. **:**::.:.*:::*:  ** 

Mb0926c|M.bovis_AF2122/97           RTKEALASARDFAAVSSHELRTPLTAMRTNLEVLSTLDLPDDQRKEVLND
Rv0902c|M.tuberculosis_H37Rv        RTKEALASARDFAAVSSHELRTPLTAMRTNLEVLSTLDLPDDQRKEVLND
MMAR_4634|M.marinum_M               RTKEALASARDFAAVSSHELRTPLTAMRTNLEVLSTLDLPDDQRKEVLND
MUL_0249|M.ulcerans_Agy99           RTKEALASARDFAAVSSHELRTPLTAMRTNLEVLSTLDLPDDQRKEVLND
MLBr_02124|M.leprae_Br4923          RTKEALASARDFAAVSSHELRTPLTAMRTNLEVLATLDLADDQRKEVLGD
MAV_1021|M.avium_104                RTKEALASARDFSAVTAHELRSPLTAMRTNLEVLSTLDMPDEQRKEVLGD
TH_0454|M.thermoresistible__bu      RTKAALASARDFASAAAHELRTPLTAMRTNLEVLSTLDMPEEQRKEVLAD
MSMEG_5663|M.smegmatis_MC2_155      RTKSALASARDFASVSAHELRTPLTAMRTNLEVLSTLDLPDEQRKEVVND
Mflv_1743|M.gilvum_PYR-GCK          RTKAALTSARDFASVSAHELRTPLTAMRTNLEVLATLELSEDGRNEVLGD
Mvan_5010|M.vanbaalenii_PYR-1       RTKAALASARDFASVSAHELRTPLTAMRTNVEVLATLDLSEEGRKEVVND
MAB_0955c|M.abscessus_ATCC_199      KTKAALESARDFAAVASHELRTPLTAMRTNLEVLSTLNLSDDQREEIIEE
                                    :** ** *****::.::****:********:***:**::.:: *:*:: :

Mb0926c|M.bovis_AF2122/97           VIRTQSRIEATLSALERLAQGELSTSDDHVPVDITDLLDRAAHDAARIYP
Rv0902c|M.tuberculosis_H37Rv        VIRTQSRIEATLSALERLAQGELSTSDDHVPVDITDLLDRAAHDAARIYP
MMAR_4634|M.marinum_M               VIRTQSRIEATLGALERLAQGELSTSEDHVPVDITELLDRAAHDAMRIYP
MUL_0249|M.ulcerans_Agy99           VIRTQSRIEATLGALERLAQGELSTSEDHVPVDITELLDRAAHDAMRIYP
MLBr_02124|M.leprae_Br4923          VIRTQSRIEATLSALERLAQGELSTSDDHVPVDITELLDRAAHDATRSYP
MAV_1021|M.avium_104                VIRTQSRIEATLTALERLAQGELSTSEDHVPVDITELLDRAAHDAMRIYP
TH_0454|M.thermoresistible__bu      VIRTQSRIEATLSALERLAQGELSTSDDHVPVDITELLDRAAHEAMRIYP
MSMEG_5663|M.smegmatis_MC2_155      VIRTQSRIEATLGALERLAQGELSTTDDHVTVDITELLDRAAHDAMRIYP
Mflv_1743|M.gilvum_PYR-GCK          VMRTQTRIEATLGALERLAQGELSTEDDHVPVDITELLDRAAHDAMRVYP
Mvan_5010|M.vanbaalenii_PYR-1       VIRTQSRIEATLGALERLAQGELSTEDDHVPVDITELLDRAAHDAMRVYP
MAB_0955c|M.abscessus_ATCC_199      TIRTQSRVEATLSALERLAQGQLTTEDDHVPVDITELLDRAAHDADRSYP
                                    .:***:*:**** ********:*:* :***.****:*******:* * **

Mb0926c|M.bovis_AF2122/97           DLDVSLVPSPTCIIVGLPAGLRLAVDNAIANAVKHGGATLVQLSAVSSRA
Rv0902c|M.tuberculosis_H37Rv        DLDVSLVPSPTCIIVGLPAGLRLAVDNAIANAVKHGGATLVQLSAVSSRA
MMAR_4634|M.marinum_M               DLDVSLVPSPTCIIVGLPAGLRLAVDNAIANAVKHGGSTRVQLSAVSSRA
MUL_0249|M.ulcerans_Agy99           DLDVSLVPSPTCIIVGLPAGLRLAVDNAIANAVKHGGSTRVQLSAVSSRA
MLBr_02124|M.leprae_Br4923          ELKVSLVPSPTCIIVGLPAGLRLAVDNAVANAVKHGGATRVQLSAVSSRA
MAV_1021|M.avium_104                GLDVSLVPSPTCIIVGLPAGLRLAVDNAIANAVKHGGATRVQLSAVSSRA
TH_0454|M.thermoresistible__bu      DLEVSLVPAPTVIIVGLPAGLRLAVDNAIANAVKHGGATRVQLSAVSSRE
MSMEG_5663|M.smegmatis_MC2_155      DLEVSLAPSPTVIIVGLPTGLRLSVDNAIANAVKHGGATRVQLSAVSSRE
Mflv_1743|M.gilvum_PYR-GCK          DLDVSLVPAPTVIIVGLPAGLRLAVDNAIANAVKHGGATRVQLSAVSSRD
Mvan_5010|M.vanbaalenii_PYR-1       DLEVSLVPAPTVIIVGLPAGLRLAVDNAIANAVKHGGASRVQLSAVSSRE
MAB_0955c|M.abscessus_ATCC_199      NLEISLVPSSTILMLGLPAGLRLVIDNAIKNAVKHGGASKIQLSATSTVH
                                     *.:**.*:.* :::***:**** :***: *******:: :****.*:  

Mb0926c|M.bovis_AF2122/97           GVEIAIDDNGSGVPEGERQVVFERFSRGSTASHSGSGLGLALVAQQAQLH
Rv0902c|M.tuberculosis_H37Rv        GVEIAIDDNGSGVPEGERQVVFERFSRGSTASHSGSGLGLALVAQQAQLH
MMAR_4634|M.marinum_M               GVEIAVDDNGSGVPEAERQMVFERFSRGSTASHSGSGLGLALVAQQAHLH
MUL_0249|M.ulcerans_Agy99           GVEIAVDDNGSGVPEAERQMVFERFSRGSTASHSGSGLGLALVAQQAHLH
MLBr_02124|M.leprae_Br4923          GVEIAVDDNGSGVPEDERQVVFERFSRGSTASHSGSGLGLALVAQQAQLH
MAV_1021|M.avium_104                GVEIAVDDNGSGVPEDERQVVFDRFSRGSTASQSGSGLGLALVAQQAQLH
TH_0454|M.thermoresistible__bu      GVEIAIDDNGTGVPEEERERVFDRFTRGSTASHSGSGLGLALVAQQAEIH
MSMEG_5663|M.smegmatis_MC2_155      GVEIAIDDNGVGVPEGERALVFDRFARGSTASRSGSGLGLALVAQQAELH
Mflv_1743|M.gilvum_PYR-GCK          GVEIAIDDDGVGVPEAEREVVFDRFSRGSTASQSGSGLGLALVAQQAELH
Mvan_5010|M.vanbaalenii_PYR-1       GVEIAIDDDGVGVPEEERTVVFDRFSRGSTASHSGSGLGLALVAQQAELH
MAB_0955c|M.abscessus_ATCC_199      GVEIAVDDNGSGIPEAERVQVFERFSRGSTASHSGSGLGLALVAQQAELH
                                    *****:**:* *:** **  **:**:******:**************.:*

Mb0926c|M.bovis_AF2122/97           GGTASLENSPLGGARLVLRLPGPS
Rv0902c|M.tuberculosis_H37Rv        GGTASLENSPLGGARLVLRLPGPS
MMAR_4634|M.marinum_M               GGTASLQNSPLGGARLLLKLPGPS
MUL_0249|M.ulcerans_Agy99           GGTASLQNSPLGGARLLLKLPGPS
MLBr_02124|M.leprae_Br4923          GGTASLETSPLGGARLLLRISAPS
MAV_1021|M.avium_104                GGTAALENSPLGGARLVLRLPGPS
TH_0454|M.thermoresistible__bu      GGTASLEASPLGGARLVLRLPGPR
MSMEG_5663|M.smegmatis_MC2_155      GGTATLAESPLGGARLLLRLPGPR
Mflv_1743|M.gilvum_PYR-GCK          GGTASLGSSPLGGARLLLRLPGPH
Mvan_5010|M.vanbaalenii_PYR-1       GGTASLEASPLGGARLLLRLPGPR
MAB_0955c|M.abscessus_ATCC_199      GGTAALESSPLGGARLVLRLPGH-
                                    ****:*  ********:*::..