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M. thermoresistible (build 8) TH_0450 (moeZ)

annotation: PROBABLE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN MOEB1 (MPT-SYNTHASE SULFURYLASE) (MOLYBDOPTERIN SYNTHASE SULPHURYLASE)
coordinates: 976783 - 977958
length: 392

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_0450 moeZ - 100% (392) PROBABLE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN MOEB1 (MPT-SYNTHASE SULFURYLASE) (MOLYBDOPTERIN SYNTHASE SULPHURYLASE)
M. thermoresistible (build 8) TH_1233 - 1e-08 33.67% (98) rhodanese-like domain protein
M. thermoresistible (build 8) TH_1234 - 7e-08 38.16% (76) metallo-beta-lactamase family protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3231c moeB1 0.0 80.87% (392) molybdopterin biosynthesis-like protein MoeZ
M. gilvum PYR-GCK Mflv_4670 - 0.0 82.14% (392) molybdopterin biosynthesis-like protein MoeZ
M. tuberculosis H37Rv Rv3206c moeB1 0.0 81.12% (392) molybdopterin biosynthesis-like protein MoeZ
M. leprae Br4923 MLBr_00817 moeZ 1e-179 78.01% (391) molybdopterin biosynthesis-like protein MoeZ
M. abscessus ATCC 19977 MAB_3525c - 0.0 80.15% (388) molybdenum cofactor biosynthesis protein MoeB1
M. marinum M MMAR_1352 moeB1 0.0 80.05% (391) molybdenum cofactor biosynthesis protein MoeB1
M. avium 104 MAV_4153 - 1e-172 73.62% (398) molybdopterin biosynthesis-like protein MoeZ
M. smegmatis MC2 155 MSMEG_1937 - 0.0 82.73% (388) molybdopterin biosynthesis-like protein MoeZ
M. ulcerans Agy99 MUL_2527 moeB1 0.0 79.80% (391) molybdopterin biosynthesis-like protein MoeZ
M. vanbaalenii PYR-1 Mvan_1797 - 0.0 80.86% (397) molybdopterin biosynthesis-like protein MoeZ

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4670|M.gilvum_PYR-GCK          ----MSTPLPPLVEPAAELTKEEVARYSRHLIIPDLGLDGQKRLKNARVL
Mvan_1797|M.vanbaalenii_PYR-1       ----MSTPLPPLVEPAAELTREEVARYSRHLIIPDVGLDGQKRLKNARVL
MSMEG_1937|M.smegmatis_MC2_155      MSANLDVSLPPLVEPADELTREEVARYSRHLIIPDLGLDGQKRLKNAKVL
MAB_3525c|M.abscessus_ATCC_199      ----MPT-LPPLVRPAAELTREEVARYSRHLIIPDLGVDGQKRLKNAKVL
TH_0450|M.thermoresistible__bu      ----VSSPLPPLVEPAAELTREEVARYSRHLIIPDVGVEGQKRLKNARVL
MMAR_1352|M.marinum_M               ---MSTTALPPLVAPAATLSREEVARYSRHLIIPDLGVDGQKRLKNARVL
MUL_2527|M.ulcerans_Agy99           ---MSTTALPPLVAPAATLSREEVARYSRHLIIPDLGVDGQKRLKNARVL
Mb3231c|M.bovis_AF2122/97           ---MS-TSLPPLVEPASALSREEVARYSRHLIIPDLGVDGQKRLKNARVL
Rv3206c|M.tuberculosis_H37Rv        ---MS-TSLPPLVEPASALSREEVARYSRHLIIPDLGVDGQKRLKNARVL
MLBr_00817|M.leprae_Br4923          -MSTSSTSLPPLVEPAGQLSRDEVIRYSRHLIIPDIGVDGQMRLKSARVL
MAV_4153|M.avium_104                ----MSTPLPPLVAPADQLTADEMARYSRQLIIPGLGVDGQKRLKNARVL
                                            ***** **  *: :*: ****:****.:*::** ***.*:**

Mflv_4670|M.gilvum_PYR-GCK          VIGAGGLGSPTLLYLAAAGVGTIGIVEFDVVDESNLQRQIIHGQSDIGRP
Mvan_1797|M.vanbaalenii_PYR-1       VIGAGGLGSPTLLYLAAAGVGTIGIVEFDLVDESNLQRQIIHGQSDIGRS
MSMEG_1937|M.smegmatis_MC2_155      VIGAGGLGSPTLLYLAAAGVGTIGIVEFDVVDESNLQRQIIHGQSDIGRS
MAB_3525c|M.abscessus_ATCC_199      VIGAGGLGSPTLLYLAAAGVGTIGIVEFDVVDESNLQRQIIHGQSDIGRS
TH_0450|M.thermoresistible__bu      VIGAGGLGSPALLYLAAAGVGTLGVIDFDVVDESNLQRQVIHGQADVGRP
MMAR_1352|M.marinum_M               VIGAGGLGSPTLLYLAAAGVGTIGIVDFDVVDESNLQRQIIHGVADVGRS
MUL_2527|M.ulcerans_Agy99           VIGAGGLGSPTLLYLAAAGVGTIGIVDFDVVDESNLQRQIIHGVADVGRS
Mb3231c|M.bovis_AF2122/97           VIGAGGLGAPTLLYLAAAGVGTIGIVDFDVVDESNLQRQVIHGVADVGRS
Rv3206c|M.tuberculosis_H37Rv        VIGAGGLGAPTLLYLAAAGVGTIGIVDFDVVDESNLQRQVIHGVADVGRS
MLBr_00817|M.leprae_Br4923          VIGAGGLGAPVLLYLAAAGVGTIGIIDFDVVDESNLQRQIIHGVADVGRS
MAV_4153|M.avium_104                VIGAGGLGAPTLLYLAAAGVGTIGIVEFDAVEESNLQRQIIHGVADVGRS
                                    ********:*.***********:*:::** *:*******:*** :*:**.

Mflv_4670|M.gilvum_PYR-GCK          KAQSAKDSVLEVNPLVTVNLHEFRLEPDNAVELFEQYDLILDGTDNFATR
Mvan_1797|M.vanbaalenii_PYR-1       KAQSAKDSIAEINPLVNVVLHEFRLEPDNAVDLFAQYDLILDGTDNFATR
MSMEG_1937|M.smegmatis_MC2_155      KAQSARDSIAEINPLVTVNLHEFRLEPDNAVDLFGQYDLILDGTDNFATR
MAB_3525c|M.abscessus_ATCC_199      KAQSARDSVLEINPLVEVRLHELRLDPENAVELFAQYDLILDGTDNFATR
TH_0450|M.thermoresistible__bu      KAESARDTIRAINPFVDVRLHQFRLDRSNAVDLFSEYDLILDGTDNFATR
MMAR_1352|M.marinum_M               KAQSARDSIVAINPLIEVRLHEFRLESDNAVDLFGHYDLIIDGTDNFATR
MUL_2527|M.ulcerans_Agy99           KAQSARDSIVAINPLIEVRLHEFRLESDNAVDLFGHYDLIIDGTDNFATR
Mb3231c|M.bovis_AF2122/97           KAQSARDSIVAINPLIRVRLHELRLAPSNAVDLFKQYDLILDGTDNFATR
Rv3206c|M.tuberculosis_H37Rv        KAQSARDSIVAINPLIRVRLHELRLAPSNAVDLFKQYDLILDGTDNFATR
MLBr_00817|M.leprae_Br4923          KAQSARDSIVAINPLVQVRLHEFRLESSNVVNLFKQYDLIVDGTDNFATR
MAV_4153|M.avium_104                KAASARDSIAAINPLVDVRLHEFRLDASNAVELFGHYDLIVDGTDNFATR
                                    ** **:*::  :**:: * **::**  .*.*:** .****:*********

Mflv_4670|M.gilvum_PYR-GCK          YLVNDAAVLAGKPYVWGSIYRFEGQVSIFWEDAP-----NGLGLNYRDLY
Mvan_1797|M.vanbaalenii_PYR-1       YLVNDAAVLAGKPYVWGSIYRFEGQISVFWEDAPADEAGNERGLNYRDLY
MSMEG_1937|M.smegmatis_MC2_155      YLVNDAAVLAGKPYVWGSIYRFEGQVSVFWEDAP-----DGLGLNYRDLY
MAB_3525c|M.abscessus_ATCC_199      YLVNDAAVLAHKPYVWGSIYRFEGQVSVFWEDAP-----DGLGLNYRDLY
TH_0450|M.thermoresistible__bu      YLVNDAAVLAGKPYVWGSIYRFEGQVSVFWEDAP-----NGQGLNYRDLY
MMAR_1352|M.marinum_M               YLVNDAAVLAGKPYVWGSIYRFEGQVSVFWEDAP-----GGLGLNYRDLY
MUL_2527|M.ulcerans_Agy99           YLVNDAAVLAGKPYVWGSIYRFEGQVSVFWEDAP-----GGLGLNYRDLY
Mb3231c|M.bovis_AF2122/97           YLVNDAAVLAGKPYVWGSIYRFEGQASVFWEDAP-----DGLGVNYRDLY
Rv3206c|M.tuberculosis_H37Rv        YLVNDAAVLAGKPYVWGSIYRFEGQASVFWEDAP-----DGLGVNYRDLY
MLBr_00817|M.leprae_Br4923          YLINDAAVLAKKPYVWGSLYRFEGQVSVFWEDAP-----DGLGLNYRDLY
MAV_4153|M.avium_104                YLINDAAVLAGKPYVWGSIYRFEGQASVCWEDAP-----DGRGLNYRDLY
                                    **:******* *******:****** *: *****     .  *:******

Mflv_4670|M.gilvum_PYR-GCK          PEPPPPGMVPSCAEGGVLGILCASIASVMGTEAIKLITGIGDPLLGRLMV
Mvan_1797|M.vanbaalenii_PYR-1       PEPPPPGMVPSCAEGGVLGILCASVGSVMGTEAIKLITGIGETLLGRLMV
MSMEG_1937|M.smegmatis_MC2_155      PEPPPPGMVPSCAEGGVLGILCSSIASIMGTEAIKLITGIGEPLLGRLMV
MAB_3525c|M.abscessus_ATCC_199      PEPPPPGMVPSCAEGGVLGILCASIASVMGTEAIKLITGIGDSLLGRLMV
TH_0450|M.thermoresistible__bu      PEPPPPGMVPSCAEGGVLGILPATIGAIQGTEAIKLITGIGETLLGQLLI
MMAR_1352|M.marinum_M               PEPPPPGMVPSCAEGGVLGIICASIASVMGTEAVKLITGIGETLLGRLMI
MUL_2527|M.ulcerans_Agy99           PEPPPPGMVPSCAEGGVLGIICASIASVMGTEAVKLITGIGETLLGRLMI
Mb3231c|M.bovis_AF2122/97           PEPPP-GMVPSCAEGGVLGIICASVASVMGTEAIKLITGIGETLLGRLLV
Rv3206c|M.tuberculosis_H37Rv        PEPPPPGMVPSCAEGGVLGIICASVASVMGTEAIKLITGIGETLLGRLLV
MLBr_00817|M.leprae_Br4923          LEPPPPGMVPSCAEGGVLGIVCASIASVMGTEAIKLITGIGAPLLGRLMI
MAV_4153|M.avium_104                PEPPPPGAVPSCAEGGVLGVVCAAIASVMSTEVIKLITGIGESLLGRLMI
                                     **** * ***********:: :::.:: .**.:******* .***:*::

Mflv_4670|M.gilvum_PYR-GCK          YDALDMSYRTIKIRKDP---STPKITELIDYEAFCG---VVSDAAAEAAA
Mvan_1797|M.vanbaalenii_PYR-1       YDALDMTYRTIKIRKDP---STPKITELIDYEAFCG---VVSDAAAEAAA
MSMEG_1937|M.smegmatis_MC2_155      YDALDMTYRTIRIRKDP---STPKITELIDYEEFCG---VVSDEAAAAAA
MAB_3525c|M.abscessus_ATCC_199      YDALDMTYRTIKIRKDP---ATPKITELIDYEAFCG---VISDEASAAVA
TH_0450|M.thermoresistible__bu      YDALEMSYRKIRIRKDP---STPAITELIDYEEFCG---VVSDAAAEAAA
MMAR_1352|M.marinum_M               YDALEMTYRTIRIRKDP---ATPKITALIDYEQFCG---VVSDDVARAAS
MUL_2527|M.ulcerans_Agy99           YDALEMTYRTIRIRKDP---ATPKITALIDYEQFCG---VVSDDVARAAS
Mb3231c|M.bovis_AF2122/97           YDALEMSYRTITIRKDP---STPKITELVDYEQFCG---VVADDAAQAAK
Rv3206c|M.tuberculosis_H37Rv        YDALEMSYRTITIRKDP---STPKITELVDYEQFCG---VVADDAAQAAK
MLBr_00817|M.leprae_Br4923          YNALEMSYRRIRIHKDP---SRPKITELTDYQQFCG---VVSDDAAQVAT
MAV_4153|M.avium_104                YDALEMSYRTIAIRRDPCDASRPAITTLVDYEQLCGAAPAASTDAATGGA
                                    *:**:*:** * *::**   : * ** * **: :**   . :  .:    

Mflv_4670|M.gilvum_PYR-GCK          DSTITPRELRELLDSGKPLALIDVREPVEWDINRIEGAELIPKGGFESGE
Mvan_1797|M.vanbaalenii_PYR-1       ESTITPRELRELMDSGKPLALIDVREPVEWDINHIEGAELIPKGAFESGE
MSMEG_1937|M.smegmatis_MC2_155      DSTVTPRELKELLDSGKPLALIDVRERVEWDINHIEGAELIPKPTFESGA
MAB_3525c|M.abscessus_ATCC_199      DSTITPRELRELLDTDKKVALIDVREPVEWDIVHIDGAELVPKSTLESGD
TH_0450|M.thermoresistible__bu      DSTVTPRELRELLDAGK-VALVDVREPVEWEINRIEGAELIPKSEIESGV
MMAR_1352|M.marinum_M               DSTITPQELRAMIDSGKKLALIDVREQVEWDIVHIDGAQLIPKSLISTGE
MUL_2527|M.ulcerans_Agy99           DSTITPQELRAMINSGKKLALIDVREQVEWDIVHIDGAQLIPKSLISTGE
Mb3231c|M.bovis_AF2122/97           GSTITPRELRDWLDSGRKLALIDVRDPVEWDIVHIDGAQLIPKSLINSGE
Rv3206c|M.tuberculosis_H37Rv        GSTITPRELRDWLDSGRKLALIDVRDPVEWDIVHIDGAQLIPKSLINSGE
MLBr_00817|M.leprae_Br4923          GSIVTPRELRELLDSGKKLALIDVREPVEWDIVHIDGAQLIPRSLINSGE
MAV_4153|M.avium_104                EAAITPRQLRELLDSGAKLALIDVREPVEFDIVHLDGAQLIPQSSINSGE
                                     : :**::*:  :::.  :**:***: **::* :::**:*:*:  :.:* 

Mflv_4670|M.gilvum_PYR-GCK          ALSKLDNDRTPVFYCKTGIRSAEVLAIVKKAGFADAMHVQGGIVAWGKQL
Mvan_1797|M.vanbaalenii_PYR-1       ALSKLKVDRTPVFYCKTGIRSAEVLAIVKKAGFSDAMHVQGGIVAWGKQL
MSMEG_1937|M.smegmatis_MC2_155      ALAKLPTDRTPVFYCKTGVRSAEVLAIAKKAGFSDAVHLQGGIVAWAKQL
MAB_3525c|M.abscessus_ATCC_199      GLAKLPQDRQAVLYCKTGIRSAEALVAVKKAGFSDAVHLQGGIAAWAKQV
TH_0450|M.thermoresistible__bu      GLAKLPMDRAPVLYCKTGVRSAEALAAVKRAGFADAMHLQGGIVAWAKQL
MMAR_1352|M.marinum_M               GLAKLPQDRTTVLYCKTGVRSAEALAALKKAGFADAVHLQGGIVAWANQM
MUL_2527|M.ulcerans_Agy99           GLAKLPQDRTTVLYCKTGVRSAEALAALKKAGFADAAHLQGGIVAWANQM
Mb3231c|M.bovis_AF2122/97           GLAKLPQDRTAVLYCKTGVRSAEALAAVKKAGFSDAVHLQGGIVAWAKQM
Rv3206c|M.tuberculosis_H37Rv        GLAKLPQDRTAVLYCKTGVRSAEALAAVKKAGFSDAVHLQGGIVAWAKQM
MLBr_00817|M.leprae_Br4923          GLAKLPQDRMSVLYCKTGVRSAETLATVKKAGFSDAVHLQGGIVAWAKQV
MAV_4153|M.avium_104                GLAKLPADRMPVLYCKTGVRSAQALAVVRQAGFSDAVHLQGGIVAWAQQM
                                    .*:**  ** .*:*****:***:.*.  ::***:** *:****.**.:*:

Mflv_4670|M.gilvum_PYR-GCK          EPDMVMY
Mvan_1797|M.vanbaalenii_PYR-1       EPDMVMY
MSMEG_1937|M.smegmatis_MC2_155      EPDMVMY
MAB_3525c|M.abscessus_ATCC_199      DPDMVMY
TH_0450|M.thermoresistible__bu      EPDMVMY
MMAR_1352|M.marinum_M               QPDMVMY
MUL_2527|M.ulcerans_Agy99           QPDMVMY
Mb3231c|M.bovis_AF2122/97           QPDMVMY
Rv3206c|M.tuberculosis_H37Rv        QPDMVMY
MLBr_00817|M.leprae_Br4923          QPDMVIY
MAV_4153|M.avium_104                QPDMILY
                                    :***::*

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_0450	moeZ	-	100% (392)	PROBABLE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN MOEB1 (MPT-SYNTHASE SULFURYLASE) (MOLYBDOPTERIN SYNTHASE SULPHURYLASE)
M. thermoresistible (build 8)	TH_1233	-	1e-08	33.67% (98)	rhodanese-like domain protein
M. thermoresistible (build 8)	TH_1234	-	7e-08	38.16% (76)	metallo-beta-lactamase family protein