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M. tuberculosis H37Rv Rv3206c (moeB1)

annotation: molybdopterin biosynthesis-like protein MoeZ
coordinates: 3582532 - 3583710
length: 392

STSLPPLVEPASALSREEVARYSRHLIIPDLGVDGQKRLKNARVLVIGAGGLGAPTLLYLAAAGVGTIGI
VDFDVVDESNLQRQVIHGVADVGRSKAQSARDSIVAINPLIRVRLHELRLAPSNAVDLFKQYDLILDGTD
NFATRYLVNDAAVLAGKPYVWGSIYRFEGQASVFWEDAPDGLGVNYRDLYPEPPPPGMVPSCAEGGVLGI
ICASVASVMGTEAIKLITGIGETLLGRLLVYDALEMSYRTITIRKDPSTPKITELVDYEQFCGVVADDAA
QAAKGSTITPRELRDWLDSGRKLALIDVRDPVEWDIVHIDGAQLIPKSLINSGEGLAKLPQDRTAVLYCK
TGVRSAEALAAVKKAGFSDAVHLQGGIVAWAKQMQPDMVMY*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3206cmoeB1-100% (392)molybdopterin biosynthesis-like protein MoeZ
M. tuberculosis H37RvRv3116moeB2e-12256.27% (391) molybdenum cofactor biosynthesis protein MoeB
M. tuberculosis H37RvRv2338cmoeW5e-1133.64% (107) hypothetical protein Rv2338c

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3231cmoeB10.099.74% (392) molybdopterin biosynthesis-like protein MoeZ
M. gilvum PYR-GCKMflv_4670-0.081.63% (392) molybdopterin biosynthesis-like protein MoeZ
M. leprae Br4923MLBr_00817moeZ0.086.45% (391) molybdopterin biosynthesis-like protein MoeZ
M. abscessus ATCC 19977MAB_3525c-0.084.06% (389) molybdenum cofactor biosynthesis protein MoeB1
M. marinum MMMAR_1352moeB10.088.49% (391) molybdenum cofactor biosynthesis protein MoeB1
M. avium 104MAV_4153-0.079.65% (398) molybdopterin biosynthesis-like protein MoeZ
M. smegmatis MC2 155MSMEG_1937-0.083.16% (392) molybdopterin biosynthesis-like protein MoeZ
M. thermoresistible (build 8)TH_0450moeZ0.081.12% (392) PROBABLE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN MOEB1
M. ulcerans Agy99MUL_2527moeB10.087.98% (391) molybdopterin biosynthesis-like protein MoeZ
M. vanbaalenii PYR-1Mvan_1797-0.081.61% (397) molybdopterin biosynthesis-like protein MoeZ

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4670|M.gilvum_PYR-GCK          ----MSTPLPPLVEPAAELTKEEVARYSRHLIIPDLGLDGQKRLKNARVL
Mvan_1797|M.vanbaalenii_PYR-1       ----MSTPLPPLVEPAAELTREEVARYSRHLIIPDVGLDGQKRLKNARVL
MSMEG_1937|M.smegmatis_MC2_155      MSANLDVSLPPLVEPADELTREEVARYSRHLIIPDLGLDGQKRLKNAKVL
MAB_3525c|M.abscessus_ATCC_199      ----MPT-LPPLVRPAAELTREEVARYSRHLIIPDLGVDGQKRLKNAKVL
TH_0450|M.thermoresistible__bu      ----VSSPLPPLVEPAAELTREEVARYSRHLIIPDVGVEGQKRLKNARVL
Rv3206c|M.tuberculosis_H37Rv        ---MS-TSLPPLVEPASALSREEVARYSRHLIIPDLGVDGQKRLKNARVL
Mb3231c|M.bovis_AF2122/97           ---MS-TSLPPLVEPASALSREEVARYSRHLIIPDLGVDGQKRLKNARVL
MMAR_1352|M.marinum_M               ---MSTTALPPLVAPAATLSREEVARYSRHLIIPDLGVDGQKRLKNARVL
MUL_2527|M.ulcerans_Agy99           ---MSTTALPPLVAPAATLSREEVARYSRHLIIPDLGVDGQKRLKNARVL
MLBr_00817|M.leprae_Br4923          -MSTSSTSLPPLVEPAGQLSRDEVIRYSRHLIIPDIGVDGQMRLKSARVL
MAV_4153|M.avium_104                ----MSTPLPPLVAPADQLTADEMARYSRQLIIPGLGVDGQKRLKNARVL
                                            ***** **  *: :*: ****:****.:*::** ***.*:**

Mflv_4670|M.gilvum_PYR-GCK          VIGAGGLGSPTLLYLAAAGVGTIGIVEFDVVDESNLQRQIIHGQSDIGRP
Mvan_1797|M.vanbaalenii_PYR-1       VIGAGGLGSPTLLYLAAAGVGTIGIVEFDLVDESNLQRQIIHGQSDIGRS
MSMEG_1937|M.smegmatis_MC2_155      VIGAGGLGSPTLLYLAAAGVGTIGIVEFDVVDESNLQRQIIHGQSDIGRS
MAB_3525c|M.abscessus_ATCC_199      VIGAGGLGSPTLLYLAAAGVGTIGIVEFDVVDESNLQRQIIHGQSDIGRS
TH_0450|M.thermoresistible__bu      VIGAGGLGSPALLYLAAAGVGTLGVIDFDVVDESNLQRQVIHGQADVGRP
Rv3206c|M.tuberculosis_H37Rv        VIGAGGLGAPTLLYLAAAGVGTIGIVDFDVVDESNLQRQVIHGVADVGRS
Mb3231c|M.bovis_AF2122/97           VIGAGGLGAPTLLYLAAAGVGTIGIVDFDVVDESNLQRQVIHGVADVGRS
MMAR_1352|M.marinum_M               VIGAGGLGSPTLLYLAAAGVGTIGIVDFDVVDESNLQRQIIHGVADVGRS
MUL_2527|M.ulcerans_Agy99           VIGAGGLGSPTLLYLAAAGVGTIGIVDFDVVDESNLQRQIIHGVADVGRS
MLBr_00817|M.leprae_Br4923          VIGAGGLGAPVLLYLAAAGVGTIGIIDFDVVDESNLQRQIIHGVADVGRS
MAV_4153|M.avium_104                VIGAGGLGAPTLLYLAAAGVGTIGIVEFDAVEESNLQRQIIHGVADVGRS
                                    ********:*.***********:*:::** *:*******:*** :*:**.

Mflv_4670|M.gilvum_PYR-GCK          KAQSAKDSVLEVNPLVTVNLHEFRLEPDNAVELFEQYDLILDGTDNFATR
Mvan_1797|M.vanbaalenii_PYR-1       KAQSAKDSIAEINPLVNVVLHEFRLEPDNAVDLFAQYDLILDGTDNFATR
MSMEG_1937|M.smegmatis_MC2_155      KAQSARDSIAEINPLVTVNLHEFRLEPDNAVDLFGQYDLILDGTDNFATR
MAB_3525c|M.abscessus_ATCC_199      KAQSARDSVLEINPLVEVRLHELRLDPENAVELFAQYDLILDGTDNFATR
TH_0450|M.thermoresistible__bu      KAESARDTIRAINPFVDVRLHQFRLDRSNAVDLFSEYDLILDGTDNFATR
Rv3206c|M.tuberculosis_H37Rv        KAQSARDSIVAINPLIRVRLHELRLAPSNAVDLFKQYDLILDGTDNFATR
Mb3231c|M.bovis_AF2122/97           KAQSARDSIVAINPLIRVRLHELRLAPSNAVDLFKQYDLILDGTDNFATR
MMAR_1352|M.marinum_M               KAQSARDSIVAINPLIEVRLHEFRLESDNAVDLFGHYDLIIDGTDNFATR
MUL_2527|M.ulcerans_Agy99           KAQSARDSIVAINPLIEVRLHEFRLESDNAVDLFGHYDLIIDGTDNFATR
MLBr_00817|M.leprae_Br4923          KAQSARDSIVAINPLVQVRLHEFRLESSNVVNLFKQYDLIVDGTDNFATR
MAV_4153|M.avium_104                KAASARDSIAAINPLVDVRLHEFRLDASNAVELFGHYDLIVDGTDNFATR
                                    ** **:*::  :**:: * **::**  .*.*:** .****:*********

Mflv_4670|M.gilvum_PYR-GCK          YLVNDAAVLAGKPYVWGSIYRFEGQVSIFWEDAP-----NGLGLNYRDLY
Mvan_1797|M.vanbaalenii_PYR-1       YLVNDAAVLAGKPYVWGSIYRFEGQISVFWEDAPADEAGNERGLNYRDLY
MSMEG_1937|M.smegmatis_MC2_155      YLVNDAAVLAGKPYVWGSIYRFEGQVSVFWEDAP-----DGLGLNYRDLY
MAB_3525c|M.abscessus_ATCC_199      YLVNDAAVLAHKPYVWGSIYRFEGQVSVFWEDAP-----DGLGLNYRDLY
TH_0450|M.thermoresistible__bu      YLVNDAAVLAGKPYVWGSIYRFEGQVSVFWEDAP-----NGQGLNYRDLY
Rv3206c|M.tuberculosis_H37Rv        YLVNDAAVLAGKPYVWGSIYRFEGQASVFWEDAP-----DGLGVNYRDLY
Mb3231c|M.bovis_AF2122/97           YLVNDAAVLAGKPYVWGSIYRFEGQASVFWEDAP-----DGLGVNYRDLY
MMAR_1352|M.marinum_M               YLVNDAAVLAGKPYVWGSIYRFEGQVSVFWEDAP-----GGLGLNYRDLY
MUL_2527|M.ulcerans_Agy99           YLVNDAAVLAGKPYVWGSIYRFEGQVSVFWEDAP-----GGLGLNYRDLY
MLBr_00817|M.leprae_Br4923          YLINDAAVLAKKPYVWGSLYRFEGQVSVFWEDAP-----DGLGLNYRDLY
MAV_4153|M.avium_104                YLINDAAVLAGKPYVWGSIYRFEGQASVCWEDAP-----DGRGLNYRDLY
                                    **:******* *******:****** *: *****     .  *:******

Mflv_4670|M.gilvum_PYR-GCK          PEPPPPGMVPSCAEGGVLGILCASIASVMGTEAIKLITGIGDPLLGRLMV
Mvan_1797|M.vanbaalenii_PYR-1       PEPPPPGMVPSCAEGGVLGILCASVGSVMGTEAIKLITGIGETLLGRLMV
MSMEG_1937|M.smegmatis_MC2_155      PEPPPPGMVPSCAEGGVLGILCSSIASIMGTEAIKLITGIGEPLLGRLMV
MAB_3525c|M.abscessus_ATCC_199      PEPPPPGMVPSCAEGGVLGILCASIASVMGTEAIKLITGIGDSLLGRLMV
TH_0450|M.thermoresistible__bu      PEPPPPGMVPSCAEGGVLGILPATIGAIQGTEAIKLITGIGETLLGQLLI
Rv3206c|M.tuberculosis_H37Rv        PEPPPPGMVPSCAEGGVLGIICASVASVMGTEAIKLITGIGETLLGRLLV
Mb3231c|M.bovis_AF2122/97           PEPPP-GMVPSCAEGGVLGIICASVASVMGTEAIKLITGIGETLLGRLLV
MMAR_1352|M.marinum_M               PEPPPPGMVPSCAEGGVLGIICASIASVMGTEAVKLITGIGETLLGRLMI
MUL_2527|M.ulcerans_Agy99           PEPPPPGMVPSCAEGGVLGIICASIASVMGTEAVKLITGIGETLLGRLMI
MLBr_00817|M.leprae_Br4923          LEPPPPGMVPSCAEGGVLGIVCASIASVMGTEAIKLITGIGAPLLGRLMI
MAV_4153|M.avium_104                PEPPPPGAVPSCAEGGVLGVVCAAIASVMSTEVIKLITGIGESLLGRLMI
                                     **** * ***********:: :::.:: .**.:******* .***:*::

Mflv_4670|M.gilvum_PYR-GCK          YDALDMSYRTIKIRKDP---STPKITELIDYEAFCG---VVSDAAAEAAA
Mvan_1797|M.vanbaalenii_PYR-1       YDALDMTYRTIKIRKDP---STPKITELIDYEAFCG---VVSDAAAEAAA
MSMEG_1937|M.smegmatis_MC2_155      YDALDMTYRTIRIRKDP---STPKITELIDYEEFCG---VVSDEAAAAAA
MAB_3525c|M.abscessus_ATCC_199      YDALDMTYRTIKIRKDP---ATPKITELIDYEAFCG---VISDEASAAVA
TH_0450|M.thermoresistible__bu      YDALEMSYRKIRIRKDP---STPAITELIDYEEFCG---VVSDAAAEAAA
Rv3206c|M.tuberculosis_H37Rv        YDALEMSYRTITIRKDP---STPKITELVDYEQFCG---VVADDAAQAAK
Mb3231c|M.bovis_AF2122/97           YDALEMSYRTITIRKDP---STPKITELVDYEQFCG---VVADDAAQAAK
MMAR_1352|M.marinum_M               YDALEMTYRTIRIRKDP---ATPKITALIDYEQFCG---VVSDDVARAAS
MUL_2527|M.ulcerans_Agy99           YDALEMTYRTIRIRKDP---ATPKITALIDYEQFCG---VVSDDVARAAS
MLBr_00817|M.leprae_Br4923          YNALEMSYRRIRIHKDP---SRPKITELTDYQQFCG---VVSDDAAQVAT
MAV_4153|M.avium_104                YDALEMSYRTIAIRRDPCDASRPAITTLVDYEQLCGAAPAASTDAATGGA
                                    *:**:*:** * *::**   : * ** * **: :**   . :  .:    

Mflv_4670|M.gilvum_PYR-GCK          DSTITPRELRELLDSGKPLALIDVREPVEWDINRIEGAELIPKGGFESGE
Mvan_1797|M.vanbaalenii_PYR-1       ESTITPRELRELMDSGKPLALIDVREPVEWDINHIEGAELIPKGAFESGE
MSMEG_1937|M.smegmatis_MC2_155      DSTVTPRELKELLDSGKPLALIDVRERVEWDINHIEGAELIPKPTFESGA
MAB_3525c|M.abscessus_ATCC_199      DSTITPRELRELLDTDKKVALIDVREPVEWDIVHIDGAELVPKSTLESGD
TH_0450|M.thermoresistible__bu      DSTVTPRELRELLDAGK-VALVDVREPVEWEINRIEGAELIPKSEIESGV
Rv3206c|M.tuberculosis_H37Rv        GSTITPRELRDWLDSGRKLALIDVRDPVEWDIVHIDGAQLIPKSLINSGE
Mb3231c|M.bovis_AF2122/97           GSTITPRELRDWLDSGRKLALIDVRDPVEWDIVHIDGAQLIPKSLINSGE
MMAR_1352|M.marinum_M               DSTITPQELRAMIDSGKKLALIDVREQVEWDIVHIDGAQLIPKSLISTGE
MUL_2527|M.ulcerans_Agy99           DSTITPQELRAMINSGKKLALIDVREQVEWDIVHIDGAQLIPKSLISTGE
MLBr_00817|M.leprae_Br4923          GSIVTPRELRELLDSGKKLALIDVREPVEWDIVHIDGAQLIPRSLINSGE
MAV_4153|M.avium_104                EAAITPRQLRELLDSGAKLALIDVREPVEFDIVHLDGAQLIPQSSINSGE
                                     : :**::*:  :::.  :**:***: **::* :::**:*:*:  :.:* 

Mflv_4670|M.gilvum_PYR-GCK          ALSKLDNDRTPVFYCKTGIRSAEVLAIVKKAGFADAMHVQGGIVAWGKQL
Mvan_1797|M.vanbaalenii_PYR-1       ALSKLKVDRTPVFYCKTGIRSAEVLAIVKKAGFSDAMHVQGGIVAWGKQL
MSMEG_1937|M.smegmatis_MC2_155      ALAKLPTDRTPVFYCKTGVRSAEVLAIAKKAGFSDAVHLQGGIVAWAKQL
MAB_3525c|M.abscessus_ATCC_199      GLAKLPQDRQAVLYCKTGIRSAEALVAVKKAGFSDAVHLQGGIAAWAKQV
TH_0450|M.thermoresistible__bu      GLAKLPMDRAPVLYCKTGVRSAEALAAVKRAGFADAMHLQGGIVAWAKQL
Rv3206c|M.tuberculosis_H37Rv        GLAKLPQDRTAVLYCKTGVRSAEALAAVKKAGFSDAVHLQGGIVAWAKQM
Mb3231c|M.bovis_AF2122/97           GLAKLPQDRTAVLYCKTGVRSAEALAAVKKAGFSDAVHLQGGIVAWAKQM
MMAR_1352|M.marinum_M               GLAKLPQDRTTVLYCKTGVRSAEALAALKKAGFADAVHLQGGIVAWANQM
MUL_2527|M.ulcerans_Agy99           GLAKLPQDRTTVLYCKTGVRSAEALAALKKAGFADAAHLQGGIVAWANQM
MLBr_00817|M.leprae_Br4923          GLAKLPQDRMSVLYCKTGVRSAETLATVKKAGFSDAVHLQGGIVAWAKQV
MAV_4153|M.avium_104                GLAKLPADRMPVLYCKTGVRSAQALAVVRQAGFSDAVHLQGGIVAWAQQM
                                    .*:**  ** .*:*****:***:.*.  ::***:** *:****.**.:*:

Mflv_4670|M.gilvum_PYR-GCK          EPDMVMY
Mvan_1797|M.vanbaalenii_PYR-1       EPDMVMY
MSMEG_1937|M.smegmatis_MC2_155      EPDMVMY
MAB_3525c|M.abscessus_ATCC_199      DPDMVMY
TH_0450|M.thermoresistible__bu      EPDMVMY
Rv3206c|M.tuberculosis_H37Rv        QPDMVMY
Mb3231c|M.bovis_AF2122/97           QPDMVMY
MMAR_1352|M.marinum_M               QPDMVMY
MUL_2527|M.ulcerans_Agy99           QPDMVMY
MLBr_00817|M.leprae_Br4923          QPDMVIY
MAV_4153|M.avium_104                QPDMILY
                                    :***::*