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M. thermoresistible (build 8) TH_0348 ()

annotation: POSSIBLE DNA GLYCOSYLASE
coordinates: 784318 - 785124
length: 269

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0348-100% (269)POSSIBLE DNA GLYCOSYLASE
M. thermoresistible (build 8)TH_1221nei6e-1828.98% (283) PROBABLE ENDONUCLEASE VIII NEI
M. thermoresistible (build 8)TH_2321-2e-1527.46% (284) POSSIBLE FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE (FAPY-DNA

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2491c-1e-11370.41% (267) DNA glycosylase
M. gilvum PYR-GCKMflv_2582-1e-11471.16% (267) formamidopyrimidine-DNA glycolase
M. tuberculosis H37RvRv2464c-1e-11370.41% (267) DNA glycosylase
M. leprae Br4923MLBr_01658fpg2e-0926.00% (150) formamidopyrimidine-DNA glycosylase
M. abscessus ATCC 19977MAB_1575-1e-10566.67% (267) formamidopyrimidine-DNA glycolase
M. marinum MMMAR_3812-1e-11672.28% (267) formamidopyrimidine-DNA glycosylase
M. avium 104MAV_1708-1e-11571.64% (268) endonuclease VIII and DNA n-glycosylase with an AP lyase
M. smegmatis MC2 155MSMEG_4683-1e-12073.41% (267) putative formamidopyrimidine-DNA glycosylase
M. ulcerans Agy99MUL_3737-1e-11471.54% (267) formamidopyrimidine-DNA glycosylase
M. vanbaalenii PYR-1Mvan_4051-1e-11771.54% (267) formamidopyrimidine-DNA glycolase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_3812|M.marinum_M               MPEGHTLHRLAR-----LHQRRFAGAPVVVSSPQGKFADSAGAVDGRVLR
MUL_3737|M.ulcerans_Agy99           MPEGHTLHRLAR-----LHQRRFAGAPVVVSSPQGKFADSAGAVDGRVLR
MAV_1708|M.avium_104                MPEGHTLHRLAR-----LHQRRYAGAPVAVTSPQGRFAEAAAVVDGRVLR
Mb2491c|M.bovis_AF2122/97           MPEGHTLHRLAR-----LHQRRFAGAPVSVSSPQGRFADSASALNGRVLR
Rv2464c|M.tuberculosis_H37Rv        MPEGHTLHRLAR-----LHQRRFAGAPVSVSSPQGRFADSASALNGRVLR
Mflv_2582|M.gilvum_PYR-GCK          MPEGHTLHRLAR-----QHQRRFGRAPVIVSSPQGRFVDGATAVNGRVLK
Mvan_4051|M.vanbaalenii_PYR-1       MPEGHTLHRLAR-----QHQRRFGRAPVIVSSPQGRFVDGAAAVNGHVFK
MSMEG_4683|M.smegmatis_MC2_155      MPEGHTLHRLAR-----LHQRRFGRTAVVVSSPQGRFADGAAAVSGQIFK
TH_0348|M.thermoresistible__bu      MPEGHTLHRLAR-----LHERRFAGVRVRVTSPQGRFAEGAAAVSGRVFQ
MAB_1575|M.abscessus_ATCC_1997      MPEGHTLHRLAR-----LHQRRFAGAPVSVSSPQGRFTEGAAAVNGRTFV
MLBr_01658|M.leprae_Br4923          MPELPEVEVVRRGLQDYIVGKTITAVRVHHPRAVRRHVAGPTDLTNRLLG
                                    ***   :. : *        :    . *  . .  :.. ..  : .: : 

MMAR_3812|M.marinum_M               A----ASAWGKHLFHHYAGGPVVHVHLGLYGAFTEWARSAGELLPDPVGQ
MUL_3737|M.ulcerans_Agy99           A----ASAWGKHLFHHYAGGPVVHVHLGLYGAFTEWVRSAGELLPDPVGQ
MAV_1708|M.avium_104                R----TSAWGKHLFHHYAGGPIVHVHLGLYGSFSEWERPGDGPLPDPVGQ
Mb2491c|M.bovis_AF2122/97           R----ASAWGKHLFHHYVGGPVVHVHLGLYGTFTEWARPTDGWLPEPAGQ
Rv2464c|M.tuberculosis_H37Rv        R----ASAWGKHLFHHYVGGPVVHVHLGLYGTFTEWARPTDGWLPEPAGQ
Mflv_2582|M.gilvum_PYR-GCK          K----ATAWGKHLFHHYDGGRVVHVHLGLYGSFTEWSLP----PLLPVGQ
Mvan_4051|M.vanbaalenii_PYR-1       K----ASAWGKHLFHHYQGGRVVHVHLGLYGTFTEWPLPDDRTQPIPVGQ
MSMEG_4683|M.smegmatis_MC2_155      R----ATAWGKHLFHHYDGGRVVHIHLGLYGAFTEWPVPAELALPLPVGQ
TH_0348|M.thermoresistible__bu      R----SDAWGKHLFHHYEGGRVVHVHLGLYGTFTEFEIPDGAEPPPPVGQ
MAB_1575|M.abscessus_ATCC_1997      Q----AHAWGKHLFHDYGPVGVVHVHLGLYGAFTELPVPMG----LPVGQ
MLBr_01658|M.leprae_Br4923          TRINGIDRRGKYLWFLLDTDIALVVHLGMSGQMLLGTVPRVDHVRISALF
                                             **:*:.       : :***: * :     .       ..  

MMAR_3812|M.marinum_M               VRMRMVGAEYGTDLRGPTVCEVIDDAQ--VADVLARLGPDPLRKDADPSW
MUL_3737|M.ulcerans_Agy99           VRMRMVGAEYGTDLRGPTVCEVIDDAQ--VADVLARLGPDPLRKDADPSW
MAV_1708|M.avium_104                VRMRMVGASHGTDLRGPTVCEVIDEGQ--VSDVLARLGPDPLRDDADPSW
Mb2491c|M.bovis_AF2122/97           VRMRMVGAEFGTDLRGPTVCESIDDGE--VADVVARLGPDPLRSDANPSS
Rv2464c|M.tuberculosis_H37Rv        VRMRMVGAEFGTDLRGPTVCESIDDGE--VADVVARLGPDPLRSDANPSS
Mflv_2582|M.gilvum_PYR-GCK          VRMRMVGTEYGADLRGPTVCEVIDEPE--IADIVARLGPDPLRPDADPSL
Mvan_4051|M.vanbaalenii_PYR-1       VRMRMLGAEYGTDLRGPTVCEVIEEPD--VADVVARLGPDPLRSDADPEL
MSMEG_4683|M.smegmatis_MC2_155      VRMRIIGAQYGTDLRGPTVCELITEPE--IVDVIAKLGPDPLRPDADASL
TH_0348|M.thermoresistible__bu      VRMRIIGGRYGTDLRGPTVCEVIGEPG--VDEIIARLGPDPLRPDADPDR
MAB_1575|M.abscessus_ATCC_1997      VRMRIEGAEFGTDLRGATACELIDAPQ--VDAILARLGPDPLRPRSDPAS
MLBr_01658|M.leprae_Br4923          DDGTVLNFTDQRTLGGWLLADLMTVDGSVLPVPVAHLARDPFDPRFDVEA
                                        : .      * *   .: :      :   :*:*. **:    :   

MMAR_3812|M.marinum_M               AWARIAKSRRPIGALLMDQKVMAGVGNVYRSELLFRHRIDPYRSGQRITE
MUL_3737|M.ulcerans_Agy99           AWARIAKSRRPIGALLMDQKVMAGVGNVYRSELLFRHRIDPYRSGQRITE
MAV_1708|M.avium_104                AWQRIAKSRRPIGALLMDQTVMAGVGNVYRSELLFRHGIDPYRAGRDVGE
Mb2491c|M.bovis_AF2122/97           AWSRITKSRRPIGALLMDQTVIAGVGNVYRNELLFRHRIDPQRPGRGIGE
Rv2464c|M.tuberculosis_H37Rv        AWSRITKSRRPIGALLMDQTVIAGVGNVYRNELLFRHRIDPQRPGRGIGE
Mflv_2582|M.gilvum_PYR-GCK          AWRRISKSRRPIGALLMDQSVIAGIGNVYRSELLFRHRTDPFRPGTSVTA
Mvan_4051|M.vanbaalenii_PYR-1       AWRRISKSRRPIGALLMDQTVIAGVGNVYRSELLFRHRTDPFRPGTTVTS
MSMEG_4683|M.smegmatis_MC2_155      AWKRITKSRRPIGALLMDQTVMAGVGNVYRSELLFRHGIDPYLPGTQLDA
TH_0348|M.thermoresistible__bu      AWTRISNSRRAIGALLMDQKVIAGIGNVYRSELLFRHGIDPFRPGKQLEE
MAB_1575|M.abscessus_ATCC_1997      AFERIAKSHRPIGALLMDQKIIAGVGNVYRSEVLFRRRIDPYREGSRLDP
MLBr_01658|M.leprae_Br4923          VVKVLRCKHSELKRQLLDQQTVSGIGNIYADEALWRAEVHGARIAATLTR
                                    .   :  .:  :   *:**  ::*:**:* .* *:*   .    .  :  

MMAR_3812|M.marinum_M               AEFSAAWTDLVALMKVGLRGGKIVVVRPEHDHGAPSYAAGRPRTYVYRRA
MUL_3737|M.ulcerans_Agy99           AEFSAAWTDLVALMKVGSRGGKIVVVRPEHDHGAPSYAAGRPRTYVYRRA
MAV_1708|M.avium_104                AEFDAAWTDLVALMKVGLRRGKIIVVRPEHDRGAPSYRPDRPRTYVYRRA
Mb2491c|M.bovis_AF2122/97           PEFDAAWNDLVSLMKVGLRRGKIIVVRPEHDHGLPSYLPDRPRTYVYRRA
Rv2464c|M.tuberculosis_H37Rv        PEFDAAWNDLVSLMKVGLRRGKIIVVRPEHDHGLPSYLPDRPRTYVYRRA
Mflv_2582|M.gilvum_PYR-GCK          DEFDALWTDLVALMKVGVRRGKIVVVLPEHDHGAPSYREGRPRTYVYRRA
Mvan_4051|M.vanbaalenii_PYR-1       DEFAEMWTDLVALMKVGVRRGKIVVVAPEHDHGAPSYREGRPRTYVYRRA
MSMEG_4683|M.smegmatis_MC2_155      AEFDAMWTDLVALMKVGVRRGKIVVVRPEHDHGAPSYRTGRPRTYVYRRA
TH_0348|M.thermoresistible__bu      AEFCAMWRDLVELMKVGLRTGRIHVVRPEHDHGPPAYAPGRPRTYVYRRT
MAB_1575|M.abscessus_ATCC_1997      EQLTALWSDLVDRMRVGLRVGKIVTVDPEHDCGDPSYAPDRPRTYVYRRA
MLBr_01658|M.leprae_Br4923          RQLAAVLDAAADVMRDSLAKGGTSFDSLYVNVNGESGYFDRS-LDAYGRE
                                     ::       .  *: .   *         : .  :   .*.   .* * 

MMAR_3812|M.marinum_M               GDPCRVCGATVGTAVLEGRNVFWCPSCQA----
MUL_3737|M.ulcerans_Agy99           GDPCRVCGATVGTAVLEGRNVFWRPSCQA----
MAV_1708|M.avium_104                GEACRVCGEPVRTAVLEGRNVFWCPTCQK----
Mb2491c|M.bovis_AF2122/97           GEPCRVCGGVIRTALLEGRNVFWCPVCQT----
Rv2464c|M.tuberculosis_H37Rv        GEPCRVCGGVIRTALLEGRNVFWCPVCQT----
Mflv_2582|M.gilvum_PYR-GCK          GDPCRVCSTPVRTVEMEARNLFWCPNCQS----
Mvan_4051|M.vanbaalenii_PYR-1       GDPCRVCATPIRTVELEGRNLFWCPACQT----
MSMEG_4683|M.smegmatis_MC2_155      GEPCRICGTPVRTAELEGRNLFWCPTCQS----
TH_0348|M.thermoresistible__bu      GEPCRVCGTAVSTAQLEARNVYWCPSCQR----
MAB_1575|M.abscessus_ATCC_1997      GAPCRVCGTPILTAEMDARNLFWCPSCQIG---
MLBr_01658|M.leprae_Br4923          GEGCRRCGAVMHREKFMNRSSFYCPRCQPRPRR
                                    *  ** *.  :    :  *. :: * **