For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
PEGHTLHRLARQHQRRFGRAPVIVSSPQGRFVDGAAAVNGHVFKKASAWGKHLFHHYQGGRVVHVHLGLY GTFTEWPLPDDRTQPIPVGQVRMRMLGAEYGTDLRGPTVCEVIEEPDVADVVARLGPDPLRSDADPELAW RRISKSRRPIGALLMDQTVIAGVGNVYRSELLFRHRTDPFRPGTTVTSDEFAEMWTDLVALMKVGVRRGK IVVVAPEHDHGAPSYREGRPRTYVYRRAGDPCRVCATPIRTVELEGRNLFWCPACQT*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_4051 | - | - | 100% (268) | formamidopyrimidine-DNA glycolase |
M. vanbaalenii PYR-1 | Mvan_1631 | - | 2e-21 | 32.13% (277) | DNA-formamidopyrimidine glycosylase |
M. vanbaalenii PYR-1 | Mvan_4883 | - | 3e-14 | 26.60% (297) | DNA-formamidopyrimidine glycosylase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2491c | - | 1e-122 | 76.12% (268) | DNA glycosylase |
M. gilvum PYR-GCK | Mflv_2582 | - | 1e-141 | 86.19% (268) | formamidopyrimidine-DNA glycolase |
M. tuberculosis H37Rv | Rv2464c | - | 1e-122 | 76.12% (268) | DNA glycosylase |
M. leprae Br4923 | MLBr_01658 | fpg | 6e-09 | 25.52% (145) | formamidopyrimidine-DNA glycosylase |
M. abscessus ATCC 19977 | MAB_1575 | - | 1e-104 | 67.04% (267) | formamidopyrimidine-DNA glycolase |
M. marinum M | MMAR_3812 | - | 1e-122 | 76.03% (267) | formamidopyrimidine-DNA glycosylase |
M. avium 104 | MAV_1708 | - | 1e-119 | 73.78% (267) | endonuclease VIII and DNA n-glycosylase with an AP lyase |
M. smegmatis MC2 155 | MSMEG_4683 | - | 1e-133 | 78.73% (268) | putative formamidopyrimidine-DNA glycosylase |
M. thermoresistible (build 8) | TH_0348 | - | 1e-117 | 71.54% (267) | POSSIBLE DNA GLYCOSYLASE |
M. ulcerans Agy99 | MUL_3737 | - | 1e-120 | 75.66% (267) | formamidopyrimidine-DNA glycosylase |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_4051|M.vanbaalenii_PYR-1 MPEGHTLHRLAR-----QHQRRFGRAPVIVSSPQGRFVDGAAAVNGHVFK Mflv_2582|M.gilvum_PYR-GCK MPEGHTLHRLAR-----QHQRRFGRAPVIVSSPQGRFVDGATAVNGRVLK MSMEG_4683|M.smegmatis_MC2_155 MPEGHTLHRLAR-----LHQRRFGRTAVVVSSPQGRFADGAAAVSGQIFK MMAR_3812|M.marinum_M MPEGHTLHRLAR-----LHQRRFAGAPVVVSSPQGKFADSAGAVDGRVLR MUL_3737|M.ulcerans_Agy99 MPEGHTLHRLAR-----LHQRRFAGAPVVVSSPQGKFADSAGAVDGRVLR MAV_1708|M.avium_104 MPEGHTLHRLAR-----LHQRRYAGAPVAVTSPQGRFAEAAAVVDGRVLR Mb2491c|M.bovis_AF2122/97 MPEGHTLHRLAR-----LHQRRFAGAPVSVSSPQGRFADSASALNGRVLR Rv2464c|M.tuberculosis_H37Rv MPEGHTLHRLAR-----LHQRRFAGAPVSVSSPQGRFADSASALNGRVLR TH_0348|M.thermoresistible__bu MPEGHTLHRLAR-----LHERRFAGVRVRVTSPQGRFAEGAAAVSGRVFQ MAB_1575|M.abscessus_ATCC_1997 MPEGHTLHRLAR-----LHQRRFAGAPVSVSSPQGRFTEGAAAVNGRTFV MLBr_01658|M.leprae_Br4923 MPELPEVEVVRRGLQDYIVGKTITAVRVHHPRAVRRHVAGPTDLTNRLLG *** :. : * : . * . . :.. .. : .: : Mvan_4051|M.vanbaalenii_PYR-1 K----ASAWGKHLFHHYQGGRVVHVHLGLYGTFTEWPLPDDRTQPIPVGQ Mflv_2582|M.gilvum_PYR-GCK K----ATAWGKHLFHHYDGGRVVHVHLGLYGSFTEWSLP----PLLPVGQ MSMEG_4683|M.smegmatis_MC2_155 R----ATAWGKHLFHHYDGGRVVHIHLGLYGAFTEWPVPAELALPLPVGQ MMAR_3812|M.marinum_M A----ASAWGKHLFHHYAGGPVVHVHLGLYGAFTEWARSAGELLPDPVGQ MUL_3737|M.ulcerans_Agy99 A----ASAWGKHLFHHYAGGPVVHVHLGLYGAFTEWVRSAGELLPDPVGQ MAV_1708|M.avium_104 R----TSAWGKHLFHHYAGGPIVHVHLGLYGSFSEWERPGDGPLPDPVGQ Mb2491c|M.bovis_AF2122/97 R----ASAWGKHLFHHYVGGPVVHVHLGLYGTFTEWARPTDGWLPEPAGQ Rv2464c|M.tuberculosis_H37Rv R----ASAWGKHLFHHYVGGPVVHVHLGLYGTFTEWARPTDGWLPEPAGQ TH_0348|M.thermoresistible__bu R----SDAWGKHLFHHYEGGRVVHVHLGLYGTFTEFEIPDGAEPPPPVGQ MAB_1575|M.abscessus_ATCC_1997 Q----AHAWGKHLFHDYGPVGVVHVHLGLYGAFTELPVPMG----LPVGQ MLBr_01658|M.leprae_Br4923 TRINGIDRRGKYLWFLLDTDIALVVHLGMSGQMLLGTVPRVDHVRISALF **:*:. : :***: * : . .. Mvan_4051|M.vanbaalenii_PYR-1 VRMRMLGAEYGTDLRGPTVCEVIEEPD--VADVVARLGPDPLRSDADPEL Mflv_2582|M.gilvum_PYR-GCK VRMRMVGTEYGADLRGPTVCEVIDEPE--IADIVARLGPDPLRPDADPSL MSMEG_4683|M.smegmatis_MC2_155 VRMRIIGAQYGTDLRGPTVCELITEPE--IVDVIAKLGPDPLRPDADASL MMAR_3812|M.marinum_M VRMRMVGAEYGTDLRGPTVCEVIDDAQ--VADVLARLGPDPLRKDADPSW MUL_3737|M.ulcerans_Agy99 VRMRMVGAEYGTDLRGPTVCEVIDDAQ--VADVLARLGPDPLRKDADPSW MAV_1708|M.avium_104 VRMRMVGASHGTDLRGPTVCEVIDEGQ--VSDVLARLGPDPLRDDADPSW Mb2491c|M.bovis_AF2122/97 VRMRMVGAEFGTDLRGPTVCESIDDGE--VADVVARLGPDPLRSDANPSS Rv2464c|M.tuberculosis_H37Rv VRMRMVGAEFGTDLRGPTVCESIDDGE--VADVVARLGPDPLRSDANPSS TH_0348|M.thermoresistible__bu VRMRIIGGRYGTDLRGPTVCEVIGEPG--VDEIIARLGPDPLRPDADPDR MAB_1575|M.abscessus_ATCC_1997 VRMRIEGAEFGTDLRGATACELIDAPQ--VDAILARLGPDPLRPRSDPAS MLBr_01658|M.leprae_Br4923 DDGTVLNFTDQRTLGGWLLADLMTVDGSVLPVPVAHLARDPFDPRFDVEA : . * * .: : : :*:*. **: : Mvan_4051|M.vanbaalenii_PYR-1 AWRRISKSRRPIGALLMDQTVIAGVGNVYRSELLFRHRTDPFRPGTTVTS Mflv_2582|M.gilvum_PYR-GCK AWRRISKSRRPIGALLMDQSVIAGIGNVYRSELLFRHRTDPFRPGTSVTA MSMEG_4683|M.smegmatis_MC2_155 AWKRITKSRRPIGALLMDQTVMAGVGNVYRSELLFRHGIDPYLPGTQLDA MMAR_3812|M.marinum_M AWARIAKSRRPIGALLMDQKVMAGVGNVYRSELLFRHRIDPYRSGQRITE MUL_3737|M.ulcerans_Agy99 AWARIAKSRRPIGALLMDQKVMAGVGNVYRSELLFRHRIDPYRSGQRITE MAV_1708|M.avium_104 AWQRIAKSRRPIGALLMDQTVMAGVGNVYRSELLFRHGIDPYRAGRDVGE Mb2491c|M.bovis_AF2122/97 AWSRITKSRRPIGALLMDQTVIAGVGNVYRNELLFRHRIDPQRPGRGIGE Rv2464c|M.tuberculosis_H37Rv AWSRITKSRRPIGALLMDQTVIAGVGNVYRNELLFRHRIDPQRPGRGIGE TH_0348|M.thermoresistible__bu AWTRISNSRRAIGALLMDQKVIAGIGNVYRSELLFRHGIDPFRPGKQLEE MAB_1575|M.abscessus_ATCC_1997 AFERIAKSHRPIGALLMDQKIIAGVGNVYRSEVLFRRRIDPYREGSRLDP MLBr_01658|M.leprae_Br4923 VVKVLRCKHSELKRQLLDQQTVSGIGNIYADEALWRAEVHGARIAATLTR . : .: : *:** ::*:**:* .* *:* . . : Mvan_4051|M.vanbaalenii_PYR-1 DEFAEMWTDLVALMKVGVRRGKIVVVAPEHDHGAPSYREGRPRTYVYRRA Mflv_2582|M.gilvum_PYR-GCK DEFDALWTDLVALMKVGVRRGKIVVVLPEHDHGAPSYREGRPRTYVYRRA MSMEG_4683|M.smegmatis_MC2_155 AEFDAMWTDLVALMKVGVRRGKIVVVRPEHDHGAPSYRTGRPRTYVYRRA MMAR_3812|M.marinum_M AEFSAAWTDLVALMKVGLRGGKIVVVRPEHDHGAPSYAAGRPRTYVYRRA MUL_3737|M.ulcerans_Agy99 AEFSAAWTDLVALMKVGSRGGKIVVVRPEHDHGAPSYAAGRPRTYVYRRA MAV_1708|M.avium_104 AEFDAAWTDLVALMKVGLRRGKIIVVRPEHDRGAPSYRPDRPRTYVYRRA Mb2491c|M.bovis_AF2122/97 PEFDAAWNDLVSLMKVGLRRGKIIVVRPEHDHGLPSYLPDRPRTYVYRRA Rv2464c|M.tuberculosis_H37Rv PEFDAAWNDLVSLMKVGLRRGKIIVVRPEHDHGLPSYLPDRPRTYVYRRA TH_0348|M.thermoresistible__bu AEFCAMWRDLVELMKVGLRTGRIHVVRPEHDHGPPAYAPGRPRTYVYRRT MAB_1575|M.abscessus_ATCC_1997 EQLTALWSDLVDRMRVGLRVGKIVTVDPEHDCGDPSYAPDRPRTYVYRRA MLBr_01658|M.leprae_Br4923 RQLAAVLDAAADVMRDSLAKGGTSFDSLYVNVNGESGYFDRS-LDAYGRE :: . *: . * : . : .*. .* * Mvan_4051|M.vanbaalenii_PYR-1 GDPCRVCATPIRTVELEGRNLFWCPACQT---- Mflv_2582|M.gilvum_PYR-GCK GDPCRVCSTPVRTVEMEARNLFWCPNCQS---- MSMEG_4683|M.smegmatis_MC2_155 GEPCRICGTPVRTAELEGRNLFWCPTCQS---- MMAR_3812|M.marinum_M GDPCRVCGATVGTAVLEGRNVFWCPSCQA---- MUL_3737|M.ulcerans_Agy99 GDPCRVCGATVGTAVLEGRNVFWRPSCQA---- MAV_1708|M.avium_104 GEACRVCGEPVRTAVLEGRNVFWCPTCQK---- Mb2491c|M.bovis_AF2122/97 GEPCRVCGGVIRTALLEGRNVFWCPVCQT---- Rv2464c|M.tuberculosis_H37Rv GEPCRVCGGVIRTALLEGRNVFWCPVCQT---- TH_0348|M.thermoresistible__bu GEPCRVCGTAVSTAQLEARNVYWCPSCQR---- MAB_1575|M.abscessus_ATCC_1997 GAPCRVCGTPILTAEMDARNLFWCPSCQIG--- MLBr_01658|M.leprae_Br4923 GEGCRRCGAVMHREKFMNRSSFYCPRCQPRPRR * ** *. : : *. :: * **