For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_2321 ()

annotation: POSSIBLE FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE (FAPY-DNA GLYCOSYLASE)
coordinates: 4546854 - 4547723
length: 290

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2321-100% (290)POSSIBLE FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE (FAPY-DNA GLYCOSYLASE)
M. thermoresistible (build 8)TH_1223fpg6e-2429.87% (298) PROBABLE FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE FPG (FAPY-DNA
M. thermoresistible (build 8)TH_1221nei1e-1529.08% (282) PROBABLE ENDONUCLEASE VIII NEI

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0969-8e-6677.71% (157) formamidopyrimidine-DNA glycosylase
M. gilvum PYR-GCKMflv_1852-1e-12475.09% (289) DNA-formamidopyrimidine glycosylase
M. tuberculosis H37RvRv0944-8e-6677.71% (157) formamidopyrimidine-DNA glycosylase
M. leprae Br4923MLBr_01658fpg2e-1828.77% (292) formamidopyrimidine-DNA glycosylase
M. abscessus ATCC 19977MAB_1038-1e-12474.05% (289) putative formamidopyrimidine-DNA glycosylase
M. marinum MMMAR_4559-1e-12776.21% (290) formamidopyrimidine-DNA glycosylase
M. avium 104MAV_1066-1e-13078.28% (290) formamidopyrimidine-DNA glycosylase
M. smegmatis MC2 155MSMEG_5545-1e-12977.47% (293) formamidopyrimidine-DNA glycosylase
M. ulcerans Agy99MUL_4418-1e-12274.14% (290) formamidopyrimidine-DNA glycosylase
M. vanbaalenii PYR-1Mvan_4883-1e-13076.09% (297) DNA-formamidopyrimidine glycosylase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1852|M.gilvum_PYR-GCK          MPELPEVEALADHLRRHAVGLTVGRVDVASLSVLKTFDP----PVSALVG
Mvan_4883|M.vanbaalenii_PYR-1       MPELPEVEALADHLRRHAVGLTVGRVDVAALSVLKTFDP----PISALYG
MAB_1038|M.abscessus_ATCC_1997      MPELPEVEALADHLRRHATGATIGRIDISALSVLKTFDP----PITALHG
MSMEG_5545|M.smegmatis_MC2_155      MPELPEVEALADHLRRHAVGRVVSRVDVSALSVLKTFDP----PVAALHG
Mb0969|M.bovis_AF2122/97            --------------------------------------------------
Rv0944|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_1066|M.avium_104                MPELPEIEALADHLRRHAVGLPIGRVDVAALSVLKTFDP----PISALHG
MMAR_4559|M.marinum_M               MPELPEIEALVDHLRRHAVGTTIGRVDVAALSVLKTFDP----PINALHG
MUL_4418|M.ulcerans_Agy99           MPELPEIGALVDHLRRPAVGTTIGRVDVAALSVLKTFDS----PINALHG
TH_2321|M.thermoresistible__bu      MPELPEVEALADHLRRHAVGQRILRIDVAALSALKTFDP----PVTALHG
MLBr_01658|M.leprae_Br4923          MPELPEVEVVRRGLQDYIVGKTITAVRVHHPRAVRRHVAGPTDLTNRLLG
                                                                                      

Mflv_1852|M.gilvum_PYR-GCK          REVTAANRWGKYLGLQAG----DLHLITHLSRAGWLRWSDKLAAAPLKPG
Mvan_4883|M.vanbaalenii_PYR-1       QEVTGANRWGKYLGLQAG----ELHLITHLSRAGWLRWSDKLAAAPLKPG
MAB_1038|M.abscessus_ATCC_1997      QPVTGATRWGKYLGLQAG----DLYLVTHLSRAGWLRWSDKLAAAPLKPG
MSMEG_5545|M.smegmatis_MC2_155      STVTAAHRWGKYLGMEVESGGAPLHLITHLSRAGWLRWSDKLAPTPLKPG
Mb0969|M.bovis_AF2122/97            --------------------------------------------------
Rv0944|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_1066|M.avium_104                QTVVGAERWGKYLGLRTE----GLFLIAHLSRAGWLRWSDRLTAAPLRPG
MMAR_4559|M.marinum_M               QTVTGAGRWGKYLGVQAG----PLWLIAHLSRAGWLRWSDKLAAAPLRPG
MUL_4418|M.ulcerans_Agy99           QTVTGAGRWGKYLGVQAG----PLWLIAHLSRAGWLRWSDKLAAAPLPPG
TH_2321|M.thermoresistible__bu      RTVTDVHRWGKYLGVRCA----ELHLVTHLSRAGWLRWSDKLSTTPLRPG
MLBr_01658|M.leprae_Br4923          TRINGIDRRGKYLWFLLDT---DIALVVHLGMSGQMLLGTVPRVDHVR--
                                                                                      

Mflv_1852|M.gilvum_PYR-GCK          KGPIALRVHLGTPGEAPG----------YDLTEAGTQKRLAVWLVTDPLA
Mvan_4883|M.vanbaalenii_PYR-1       KGPIALRVHLGPPGESPGPNVAAGAAPGFDLTEAGTQKRLAVWLVTDPMA
MAB_1038|M.abscessus_ATCC_1997      KGPIALRVHLGTPGDAPG----------FDLTEAGTQKRLAVWVVRDPAA
MSMEG_5545|M.smegmatis_MC2_155      KGPIALRVHLG---DSQG----------FDLTEAGTQKRLAVWVVRDPMD
Mb0969|M.bovis_AF2122/97            --------------------------------MAGTPQ------------
Rv0944|M.tuberculosis_H37Rv         --------------------------------MAGTPQ------------
MAV_1066|M.avium_104                KGPIALRVHLGSPGAAPG----------FDLTEAGTQKRLAVWLVDDPAR
MMAR_4559|M.marinum_M               KGPIALRVHLGTPGVAPG----------FDLTEAGTQKRLAVWLVEDPRQ
MUL_4418|M.ulcerans_Agy99           KGPIALRVHLGTLGVAPG----------FDLTEAGTQKRLAVWLVEDPRQ
TH_2321|M.thermoresistible__bu      KGPIALRVHVGDGAEPAG--------IGFDLTEAGTQKRLAVWVVDDPAQ
MLBr_01658|M.leprae_Br4923          ---ISALFDDGTVLNFTD------------QRTLGGWLLADLMTVDGSVL
                                                                      *               

Mflv_1852|M.gilvum_PYR-GCK          VPQIASLGPDALS--LTLPAFTEMLSGESGRIKTVITDQKVISGIGNAYS
Mvan_4883|M.vanbaalenii_PYR-1       VPQIASLGPDALS--LTGQALAEVLGGQSGRIKTVITDQKVIAGIGNAYS
MAB_1038|M.abscessus_ATCC_1997      VPQIASLGPDALS--LTADGLADILAGTTARLKNVITDQRVISGIGNAYS
MSMEG_5545|M.smegmatis_MC2_155      VPQIASLGPDALS--LDSTALAGVLAGNSGRIKTVITDQKVMAGIGNAYS
Mb0969|M.bovis_AF2122/97            -P--RALGPDALD--VSTDDLAGLLAGNTGRIKTVITDQKVIAGIGNAYS
Rv0944|M.tuberculosis_H37Rv         -P--RALGPDALD--VSTDDLAGLLAGNTGRIKTVITDQKVIAGIGNAYS
MAV_1066|M.avium_104                VPGIAALGPDALD--LDVDALADLLAGNTGRIKTVITDQKVIAGIGNAYS
MMAR_4559|M.marinum_M               VPGIATLGPDALE--LGPEELAGVLGPHTGRIKTVITDQKVIAGIGNAYS
MUL_4418|M.ulcerans_Agy99           VPGIATLGPDALE--LGPEELAGVLGPHTGRIKTVMTDQKVIAGIGNAYS
TH_2321|M.thermoresistible__bu      VPGIAALGPDALD--VDRDTLAELLGRSTGRIKTVLTDQKVIAGIGNAYS
MLBr_01658|M.leprae_Br4923          PVPVAHLARDPFDPRFDVEAVVKVLRCKHSELKRQLLDQQTVSGIGNIYA
                                          *. *.:.  .    .. :*    ..:*  : **:.::**** *:

Mflv_1852|M.gilvum_PYR-GCK          DEILHVARLSPFATANKLTEAQRADLYDAMITVLTDAVTR---SVGQQAA
Mvan_4883|M.vanbaalenii_PYR-1       DEILHVAKLSPFATANKLTPSQLVTLHDAMISVLTDAVTR---SVGQQAA
MAB_1038|M.abscessus_ATCC_1997      DEILHVAKLSPFASGKTLSEGQLTALYEAMQSVLTDAVER---SVGQQAA
MSMEG_5545|M.smegmatis_MC2_155      DEILHVAKLSPFTTAGKLTDAQLGALHDAMITVLTDAVSR---SVGQQAA
Mb0969|M.bovis_AF2122/97            DEILHVAKISPFATAGKLSGAQLTCLHEAMASVLSDAVRR---SVGQGAA
Rv0944|M.tuberculosis_H37Rv         DEILHVAKISPFATAGKLSGAQLTCLHEAMASVLSDAVRR---SVGQGAA
MAV_1066|M.avium_104                DEILHVAKISPFATAGKLSDKQLATLHDAMVTVLTDAVSR---SVGQGAA
MMAR_4559|M.marinum_M               DEILHVAKISPFATAAKLSEEQLAALHDAVVSVLTDAVSR---SVGQGAA
MUL_4418|M.ulcerans_Agy99           DEILHVAKISPFATAAKLSEEQLAALHDAVVSVLTDAVSR---SVGQGAA
TH_2321|M.thermoresistible__bu      DEILHTARLSPFATANRLTAPQLDALHEAMIGVLTDAVQR---SVGQQAA
MLBr_01658|M.leprae_Br4923          DEALWRAEVHGARIAATLTRRQLAAVLDAAADVMRDSLAKGGTSFDSLYV
                                    ** *  *.:     .  *:  *   : :*   *: *:: :   *...  .

Mflv_1852|M.gilvum_PYR-GCK          TLKGEK---RSGLRVHARTGLPCPVCVDTVREVSFADKSFQYCATCQTGG
Mvan_4883|M.vanbaalenii_PYR-1       TLKGEK---RSGLRVHARTGLPCPVCGDTVREVSFADKSFQYCPTCQTGG
MAB_1038|M.abscessus_ATCC_1997      TLKGEK---RSGLRVHARAGMPCPVCGDVVREVSFADKSFQYCPTCQTGG
MSMEG_5545|M.smegmatis_MC2_155      TLKGEK---RSGLRVHARTGLPCPVCGDTVREVSFADKSFQYCPTCQTGG
Mb0969|M.bovis_AF2122/97            MLKGEK---RSGLRVHARTGLPCPVCGDTVREVSFADKSFQYCPTCQTGG
Rv0944|M.tuberculosis_H37Rv         MLKGEK---RSGLRVHARTGLPCPVCGDTVREVSFADKSFQYCPTCQTGG
MAV_1066|M.avium_104                MLKGEK---RSGLRVHARTGLPCPVCGDTVREVSFADKSFQYCPTCQTGG
MMAR_4559|M.marinum_M               TLKGEK---RSGLRVHARTGLPCPVCGDTVREVSFADKSFQYCATCQTGG
MUL_4418|M.ulcerans_Agy99           TLKGEK---RSGLRVHARTGLPCPVCGDTVREVSFADKSFQYCATCQTGG
TH_2321|M.thermoresistible__bu      TLKGEK---RAGLRVHGRTGLPCPVCGDSVREVSFADKSFQYCPTCQTGG
MLBr_01658|M.leprae_Br4923          NVNGESGYFDRSLDAYGREGEGCRRCGAVMHREKFMNRSSFYCPRCQPRP
                                     ::**.     .* .:.* *  *  *   ::. .* ::*  **. **.  

Mflv_1852|M.gilvum_PYR-GCK          KVLADRRMSRLLK
Mvan_4883|M.vanbaalenii_PYR-1       KVLADRRMSRLLK
MAB_1038|M.abscessus_ATCC_1997      KVLADRRLSRLLK
MSMEG_5545|M.smegmatis_MC2_155      KVLADRRMSRLLK
Mb0969|M.bovis_AF2122/97            KALADRRMSRLLK
Rv0944|M.tuberculosis_H37Rv         KALADRRMSRLLK
MAV_1066|M.avium_104                KILADRRMSRLLK
MMAR_4559|M.marinum_M               KVLADRRMSRLLK
MUL_4418|M.ulcerans_Agy99           KVLPHRRMSRLLK
TH_2321|M.thermoresistible__bu      RILADRRMSKLLK
MLBr_01658|M.leprae_Br4923          RR-----------
                                    :