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M. thermoresistible (build 8) TH_0255 (-)

annotation: acetyl-CoA acetyltransferase
coordinates: 559628 - 560773
length: 382

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0255--100% (382)acetyl-CoA acetyltransferase
M. thermoresistible (build 8)TH_0166fadA6e-10752.32% (388) PROBABLE ACETYL-CoA ACETYLTRANSFERASE FADA6
M. thermoresistible (build 8)TH_2071fadA64e-9948.96% (386) PROBABLE ACETYL-CoA ACETYLTRANSFERASE FADA6

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3586cfadA61e-10551.80% (388) acetyl-CoA acetyltransferase
M. gilvum PYR-GCKMflv_2445-0.083.80% (389) acetyl-CoA acetyltransferase
M. tuberculosis H37RvRv3556cfadA61e-10551.80% (388) acetyl-CoA acetyltransferase
M. leprae Br4923MLBr_02162fadA6e-7744.14% (401) acetyl-CoA acetyltransferase
M. abscessus ATCC 19977MAB_3455c-1e-11255.92% (397) putative acyl-CoA thiolase
M. marinum MMMAR_4740fadA6_20.085.83% (381) acetyl-CoA acetyltransferase FadA6_2
M. avium 104MAV_0909-0.084.38% (384) acetyl-CoA acetyltransferase
M. smegmatis MC2 155MSMEG_4833-0.083.20% (381) putative acyl-CoA dehydrogenase
M. ulcerans Agy99MUL_0971fadA6_31e-14265.97% (382) acetyl-CoA acetyltransferase FadA6_3
M. vanbaalenii PYR-1Mvan_4206-0.085.00% (380) acetyl-CoA acetyltransferases

CLUSTAL 2.0.9 multiple sequence alignment


Mb3586c|M.bovis_AF2122/97           ----MTEAYVIDAVRTAVGKR--GGALAGIHPVDLGALAWRGLLDR-TDI
Rv3556c|M.tuberculosis_H37Rv        ----MTEAYVIDAVRTAVGKR--GGALAGIHPVDLGALAWRGLLDR-TDI
Mflv_2445|M.gilvum_PYR-GCK          ----MRETVIVGAVRTPVGKR--NGGLSEQHAADLSAVVLNEVVER-TGV
Mvan_4206|M.vanbaalenii_PYR-1       ----MRETVIVGAVRTPVGKR--NGGLSEQHAADLSAVVLNELVER-TGV
MMAR_4740|M.marinum_M               MGGTGRETVIVEAVRTAVGKR--NGGLSGMHAADLSAVVLNELLER-AGV
MAV_0909|M.avium_104                ----MRETVIVEAVRTPVGKR--NGALSGMHAADLSAIVLNELVER-TGI
MSMEG_4833|M.smegmatis_MC2_155      ----MRETVIVEAVRTPVGKR--NGGLSGMHAADLSGLVLNALVEK-AGI
TH_0255|M.thermoresistible__bu      ----MRETVIVEAVRTAVGKR--NGALADVHAADLSAVVLSELVER-AGI
MUL_0971|M.ulcerans_Agy99           ----MAEAVIVEAVRSPVGKR--NGALSGVHPADLSAQVLNGLADK-AGI
MAB_3455c|M.abscessus_ATCC_199      ----MRDAVIIDAVRTPVGKGKPGGSLSGVHPVDLHAHAIRELVER-AGI
MLBr_02162|M.leprae_Br4923          ---MSEEAFIYEAIRTPRGKQK-NGSLHEVKPVSLVVGLVEELRKRNPDL
                                          :: :  *:*:. **   .*.*   :...*       : .: ..:

Mb3586c|M.bovis_AF2122/97           DPAAVDDVIAGCVDAIGGQAGNIARLSWLAAGYPEEVPGVTVDRQCGSSQ
Rv3556c|M.tuberculosis_H37Rv        DPAAVDDVIAGCVDAIGGQAGNIARLSWLAAGYPEEVPGVTVDRQCGSSQ
Mflv_2445|M.gilvum_PYR-GCK          DPDLVDDVVWGCVSQVGDQSSNIGRYAVLAAGWPEHIPGTTVNRACGSSQ
Mvan_4206|M.vanbaalenii_PYR-1       DTDVIDDVIWGCVSQVGDQSSNIGRYSVLAAGWPEHIPGTTVNRACGSSQ
MMAR_4740|M.marinum_M               GPEIVDDVIWGCVSQVGDQSSNIGRYAVLAAGWPETIPGTTVNRACGSSQ
MAV_0909|M.avium_104                GPELIDDVVWGCVSQVGDQSSNIGRYAVLAAGWPESIPGTTVNRACGSSQ
MSMEG_4833|M.smegmatis_MC2_155      GPDIIDDVIWGCVSQVGDQSSNIGRFAVLAAGWPEHIPGTTVNRACGSSQ
TH_0255|M.thermoresistible__bu      DPELIDDVIWGCVSQVGDQSSNIGRYAVLAAGWPETIPGTTVNRACGSSQ
MUL_0971|M.ulcerans_Agy99           DPEIVDDVIWGCVMQAGEQALDIARTSLLTAGWPETVPGVTVDRQCGSSQ
MAB_3455c|M.abscessus_ATCC_199      DPALIDDVISGAVGQVGEQSSNTARWAALAAGLPETVPAVTVDRQCGSSQ
MLBr_02162|M.leprae_Br4923          DENLISDVILGCVSPVGDQGGDIARATVLAAGLPVTAGGVQLNRFCASGL
                                    .   :.**: *.*   * *. : .* : *:** *    .. ::* *.*. 

Mb3586c|M.bovis_AF2122/97           QAISFGAQAIMSGTADVIVAGGVQNMSQIPISSAMTVGEQFGFTSPTNES
Rv3556c|M.tuberculosis_H37Rv        QAISFGAQAIMSGTADVIVAGGVQNMSQIPISSAMTVGEQFGFTSPTNES
Mflv_2445|M.gilvum_PYR-GCK          QALDFAVQAVMSGQQDVVVAGGVEVMSRVPLGSARSTG--------MPYG
Mvan_4206|M.vanbaalenii_PYR-1       QALDFAVQAVMSGQQDVVVAGGVEVMSRVPLGAARATG--------MPYG
MMAR_4740|M.marinum_M               QALDFAVQAVMSGQQDVVVAGGVEVMSRVPLGAARATG--------MPYG
MAV_0909|M.avium_104                QALDFAVQAVMSGQQDVVVAGGVEVMSRVPLGAARATG--------TPYG
MSMEG_4833|M.smegmatis_MC2_155      QALDFAVQAVMSGQQDVVVAGGVEVMSRVPLGAARATG--------MPYG
TH_0255|M.thermoresistible__bu      QALDFAVHAVMSGQQDVVVAGGVEVMSRVPLGAARATG--------MPYG
MUL_0971|M.ulcerans_Agy99           QSVHFAAAGVVAGHYDVVVAGGVESMSRTPMGSSLANGG-------RPYS
MAB_3455c|M.abscessus_ATCC_199      QAIHFAAQGVIAGAYDVVIASGIESMSRVPMGSQ-SLG-------KDFFG
MLBr_02162|M.leprae_Br4923          EAVNTAAQKVRSGWDDLVLAGGVESMSRVPMGSDG-----------GAMG
                                    :::  ..  : :*  *:::*.*:: **: *:.:                .

Mb3586c|M.bovis_AF2122/97           KQWLHRYGDQEISQFRGSELIAEKWNLSREEMERYSLTSHERAFAAIRAG
Rv3556c|M.tuberculosis_H37Rv        KQWLHRYGDQEISQFRGSELIAEKWNLSREEMERYSLTSHERAFAAIRAG
Mflv_2445|M.gilvum_PYR-GCK          PKVLARYDDFSFNQGISAEMISAQWGLSRTRLDEYSAQSHERAAAAQDAG
Mvan_4206|M.vanbaalenii_PYR-1       PKVFARYDDFSFNQGISAEMISQKWGFSRTQLDEYSALSHERAAAAQDAG
MMAR_4740|M.marinum_M               PKVLARYDNFSFNQGLSAELIAKKWGFSRDRLDEYSALSHQRAAAAQDRG
MAV_0909|M.avium_104                PKVLARYDDFSFNQGLSAEMIAKKWGFSRTQLDEYSVRSHERAAAAQDAG
MSMEG_4833|M.smegmatis_MC2_155      PKVIDRYRDFSFNQGISAEMIAQKWGFTRTQLDEYSVASHERAAAAQDSG
TH_0255|M.thermoresistible__bu      PKVLERYDNFGFNQGISAELIAERWNLSRTRLDEYSAQSHERAAAAQSSG
MUL_0971|M.ulcerans_Agy99           QTFLERYDGRIPNQGLGAEMIAEQWGLSRTMLDEFSLMSHEKAAAAQDSG
MAB_3455c|M.abscessus_ATCC_199      SEVARRYPEGLVPQGISAELIAAKWNLSREQLDTFAAESHRRAAQAWSEG
MLBr_02162|M.leprae_Br4923          LDPATNYDVMFVPQGIGADLIATIEGFSRDDVDVYALRSQEKAAAAWSGG
                                         .*      *  .:::*:   .::*  :: ::  *:.:*  *   *

Mb3586c|M.bovis_AF2122/97           HFENEIITVETESGP---------FRVDEGPRE-SSLEKMAGLQP-LVEG
Rv3556c|M.tuberculosis_H37Rv        HFENEIITVETESGP---------FRVDEGPRE-SSLEKMAGLQP-LVEG
Mflv_2445|M.gilvum_PYR-GCK          AFKDQIVPVFTEAADARSNSGGSVVTDDEGIRRGTTAEKLSGLKPAFTED
Mvan_4206|M.vanbaalenii_PYR-1       AFKDQIVPVFTD---------GGIVTDDEGIRRGTTVEKLAGLKPAFTED
MMAR_4740|M.marinum_M               AFTDQIVPVFPAAAT--------VVDTDEGVRRGTTVEKLAGLKPAFVED
MAV_0909|M.avium_104                AFTDQIVPVFVEDAEN------KVVAADEGVRRGSSVEKLAALKPAFAED
MSMEG_4833|M.smegmatis_MC2_155      AFETQMITVFPDDGDP--------VVADEGVRRGTTVDKLANLKPAFKDD
TH_0255|M.thermoresistible__bu      AFKDQIVPVFTDDA---------VVTEDEGIRRGTTVEKLATLKPAFTEN
MUL_0971|M.ulcerans_Agy99           AFDDQIVGIKDQDGNP--------VLKDEGIRRGTPMEKMAALKPAFKED
MAB_3455c|M.abscessus_ATCC_199      RFARDVVPIKAPDVNG----DLVEVSTDESVRPSTTVEVLAGLKPAFRNE
MLBr_02162|M.leprae_Br4923          YFAKSVVPVRDQNGLL-------ILDHDEHMRPDTSKEGLAKLKPAFEGL
                                     *  .:: :               .  **  *  :. : :: *:* :   

Mb3586c|M.bovis_AF2122/97           G---------------------RLTAAMASQISDGASAVLLASERAVKDH
Rv3556c|M.tuberculosis_H37Rv        G---------------------RLTAAMASQISDGASAVLLASERAVKDH
Mflv_2445|M.gilvum_PYR-GCK          G---------------------VIHAGNSSQISDGAAALLVMTAENAVNL
Mvan_4206|M.vanbaalenii_PYR-1       G---------------------VIHAGNSSQISDGAAALLVTTMENAVNL
MMAR_4740|M.marinum_M               G---------------------LIHAGNSSQISDGSAALLVTTSEMALEL
MAV_0909|M.avium_104                G---------------------VIHAGNSSQISDGAAALLVTTAEMAVEL
MSMEG_4833|M.smegmatis_MC2_155      G---------------------VIHAGNSSQISDGAAALLVMTAENAVAM
TH_0255|M.thermoresistible__bu      G---------------------VIHAGNSSQISDGAAALLVMTAETAVTL
MUL_0971|M.ulcerans_Agy99           G---------------------VIHAGNSSQISDGSAALLFMSAEKAKSL
MAB_3455c|M.abscessus_ATCC_199      LWQ-----------QRFPGLDWKVTAGNSSPINDGASAVLITSSETAHRL
MLBr_02162|M.leprae_Br4923          AAMGGFDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVMIGSEAVGKSQ
                                                             .. :* * **:: ::. :       

Mb3586c|M.bovis_AF2122/97           GLRPRARIHHISARAADPVFMLTGPIPATRYALDKTGLAIDDIDTVEINE
Rv3556c|M.tuberculosis_H37Rv        GLRPRARIHHISARAADPVFMLTGPIPATRYALDKTGLAIDDIDTVEINE
Mflv_2445|M.gilvum_PYR-GCK          GLTPLVRYRAGAVTGADPKLMLTGPIPATAKVLHKAGVTLDEVGVYEVNE
Mvan_4206|M.vanbaalenii_PYR-1       GLTPLVRYRAGAVTGADPRLMLTGPIPATEKVLHKAGVTLDEVGVYEVNE
MMAR_4740|M.marinum_M               GLTPIVRYRAGAVTGADPVLMLTGPIPATEKVLGKSGVSLDEVGVFEVNE
MAV_0909|M.avium_104                GLTPIVRYVAGAVTGADPVLMLTGPIPATEKVLKKAGVALSDVGVFEVNE
MSMEG_4833|M.smegmatis_MC2_155      GLSPIVRYRAGAVAGADPVLMLTGPIPATEKVLHKAGVRLDEIGVFEVNE
TH_0255|M.thermoresistible__bu      GLTPIVRYRAGAVTGADPVLMLTGPIPATEKVLRKTGLNIDDIGVFEVNE
MUL_0971|M.ulcerans_Agy99           GMKPIAKVHTAVLAGADPVIMLTAPIPATQKVLKRSGLSIGDIGAYEVNE
MAB_3455c|M.abscessus_ATCC_199      GLTPRARVHSVAVVGDDPLYMLTGIIPATAKVLDRAGLSLADIDAFEVNE
MLBr_02162|M.leprae_Br4923          GLTPRARMVATATSGADPVIMLTGPTPATRKVLDRAGLTVDDIDLFELNE
                                    *: * .:       . **  ***.  ***  .* ::*: : ::.  *:**

Mb3586c|M.bovis_AF2122/97           AFAPVVMAWLKEIKADPAKVNPNGGAIALGHPLGATGAKLFTTMLGELER
Rv3556c|M.tuberculosis_H37Rv        AFAPVVMAWLKEIKADPAKVNPNGGAIALGHPLGATGAKLFTTMLGELER
Mflv_2445|M.gilvum_PYR-GCK          AFAPVPLAWLADTGADEAKLNPLGGAIALGHPLGASGAVLMTRMIHHMRD
Mvan_4206|M.vanbaalenii_PYR-1       AFAPVPLAWLADTGADAAKLNPLGGAIALGHPLGASGAVLMTRMIHHMRD
MMAR_4740|M.marinum_M               AFAPVPLAWLAETGADPGRLNPLGGAIALGHPLGASGAVLMTRMVHHMRD
MAV_0909|M.avium_104                AFAPVPLAWLAETGADAARTNPLGGAIALGHPLGASGAVLMTRMAHHMRD
MSMEG_4833|M.smegmatis_MC2_155      AFAPVPLAWQAETGADPAKLNPLGGAIALGHPLGASGAVLMTRMINHMRD
TH_0255|M.thermoresistible__bu      AFAPVPLAWQAETGADPAKLNPLGGAIALGHPLGASGAVLMTRMVHHMRA
MUL_0971|M.ulcerans_Agy99           AFAPVPLAWLCDIGADENRLNPNGGAIALGHPLGGSGARVMTTLLYHMRD
MAB_3455c|M.abscessus_ATCC_199      AFASVVLAWQAETGADLSKVNVNGGATAIGHPLGASGGRLMTTLVSVLEQ
MLBr_02162|M.leprae_Br4923          AFASVVLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAMILGTMVDELER
                                    ***.* : :  :      : *  *** *:*****.:*. ::  :   :. 

Mb3586c|M.bovis_AF2122/97           IGGRYGLQTMCEGGGTANVTIIERL-
Rv3556c|M.tuberculosis_H37Rv        IGGRYGLQTMCEGGGTANVTIIERL-
Mflv_2445|M.gilvum_PYR-GCK          NGIRYGLQTMCEGGGTANATLVELVK
Mvan_4206|M.vanbaalenii_PYR-1       NGIRYGLQTMCEGGGTANATLIELVK
MMAR_4740|M.marinum_M               NGIRYGLQTMCEGGGTANATLVELLS
MAV_0909|M.avium_104                NGIRYGLQTMCEGGGTANATLVELVS
MSMEG_4833|M.smegmatis_MC2_155      NGIQYGLQTMCEGGGTANATIVELLG
TH_0255|M.thermoresistible__bu      NGIRYGLQTMCEGGGTANATVVELLA
MUL_0971|M.ulcerans_Agy99           NGIRYGLQTMCEGGGQANATVLELL-
MAB_3455c|M.abscessus_ATCC_199      GGGRYGLQTMCEAGGLANATILERL-
MLBr_02162|M.leprae_Br4923          CNARRALVTLCIGAGMGVATIIERV-
                                     . : .* *:* ..* . .*::* :