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M. thermoresistible (build 8) TH_0166 (fadA6)

annotation: PROBABLE ACETYL-CoA ACETYLTRANSFERASE FADA6 (ACETOACETYL-CoA THIOLASE)
coordinates: 359445 - 360602
length: 386

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_0166 fadA6 - 100% (386) PROBABLE ACETYL-CoA ACETYLTRANSFERASE FADA6 (ACETOACETYL-CoA THIOLASE)
M. thermoresistible (build 8) TH_2071 fadA6 e-146 65.30% (389) PROBABLE ACETYL-CoA ACETYLTRANSFERASE FADA6
M. thermoresistible (build 8) TH_0255 - e-107 52.32% (388) acetyl-CoA acetyltransferase

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3586c fadA6 1e-144 66.41% (387) acetyl-CoA acetyltransferase
M. gilvum PYR-GCK Mflv_1484 - 1e-145 66.84% (386) acetyl-CoA acetyltransferase
M. tuberculosis H37Rv Rv3556c fadA6 1e-144 66.41% (387) acetyl-CoA acetyltransferase
M. leprae Br4923 MLBr_02162 fadA 2e-73 41.16% (413) acetyl-CoA acetyltransferase
M. abscessus ATCC 19977 MAB_0600 - 1e-144 66.84% (383) acetyl-CoA acetyltransferase
M. marinum M MMAR_5045 fadA6_1 1e-144 66.93% (387) acetyl-CoA acetyltransferase FadA6_1
M. avium 104 MAV_5069 - 0.0 87.21% (383) acetyl-CoA acetyltransferase
M. smegmatis MC2 155 MSMEG_6008 - 1e-150 67.62% (383) acetyl-CoA acetyltransferase
M. ulcerans Agy99 MUL_4119 fadA6_1 1e-144 66.67% (387) acetyl-CoA acetyltransferase
M. vanbaalenii PYR-1 Mvan_5282 - 1e-146 67.36% (383) acetyl-CoA acetyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


TH_0166|M.thermoresistible__bu      -MAMTEAYIVDAVRTPVGK-RNGGLSGAHPADMAAHVIKTLVGRH-DFDP
MAV_5069|M.avium_104                ---MTEAYIVDAVRTAVGK-RGGGLAGVHPADMAAHVIKTLVGRH-DIDP
Mb3586c|M.bovis_AF2122/97           ---MTEAYVIDAVRTAVGK-RGGALAGIHPVDLGALAWRGLLDRT-DIDP
Rv3556c|M.tuberculosis_H37Rv        ---MTEAYVIDAVRTAVGK-RGGALAGIHPVDLGALAWRGLLDRT-DIDP
MMAR_5045|M.marinum_M               ---MPEAYVIDAVRTAVGK-RGGALAGVHPVDLGALGWRGLLDRV-DVDP
MUL_4119|M.ulcerans_Agy99           ---MPEAYVIDAVRTAVGK-RGGALAGVHPVDLGALGWRGLLDRV-DVDP
Mflv_1484|M.gilvum_PYR-GCK          MAVASEAYVIDAVRTAVGK-RNGSLAGVHPVDLGAAAWRGLFERN-DVDP
Mvan_5282|M.vanbaalenii_PYR-1       ---MAEAYVIDAVRTAIGK-RNGSLAGMHPVDLGAAGWRGLFARN-DVDP
MSMEG_6008|M.smegmatis_MC2_155      ---MPEAYIIDAVRTPVGK-KNGSLAQVHPIDLGVHVFRSIFDRV-DVDP
MAB_0600|M.abscessus_ATCC_1997      ---MSEAYIIDAVRTAVGK-RNGALSKVHPLDLGAATFKGLFDRV-DVDP
MLBr_02162|M.leprae_Br4923          --MSEEAFIYEAIRTPRGKQKNGSLHEVKPVSLVVGLVEELRKRNPDLDE
                                         **:: :*:**. ** :.*.*   :* .: .   . :  *  *.* 

TH_0166|M.thermoresistible__bu      AAIDDVIFGCLDNIGSQAGDIARTAALAAGLPESVPGVTIDRQCGSAQQA
MAV_5069|M.avium_104                AAIDDVILGCLDNIGSQAGDIARTAALAAGLPESVPGVTVDRQCGSAQQA
Mb3586c|M.bovis_AF2122/97           AAVDDVIAGCVDAIGGQAGNIARLSWLAAGYPEEVPGVTVDRQCGSSQQA
Rv3556c|M.tuberculosis_H37Rv        AAVDDVIAGCVDAIGGQAGNIARLSWLAAGYPEEVPGVTVDRQCGSSQQA
MMAR_5045|M.marinum_M               AAVDDVIAGCVDAIGGQAGNIARLSWLAAGYPEEVPGVTVDRQCGSSQQA
MUL_4119|M.ulcerans_Agy99           AAVDDVIAGCVDAIGGQAGNIARLSWLAAGYPEEVPGVTVDRQCGSSQQA
Mflv_1484|M.gilvum_PYR-GCK          GAVDDVIAGCVDAIGPQAGNIARLSWLAAGFPEEVPGVTVDRQCGSSQQA
Mvan_5282|M.vanbaalenii_PYR-1       GAVDDVIAGCVDAIGPQAGNIARLSWLAAGYPEEVPGVTVDRQCGSSQQA
MSMEG_6008|M.smegmatis_MC2_155      GAVDDVIVGCVDAIGGQAGNIGRNAWLAAGYPEEVPGVTVDRQCGSSQQA
MAB_0600|M.abscessus_ATCC_1997      DAIDDVYMGVLDAIGGQAGNAGRLAWLAGGYPEEVPGATVDRQCGSSQQA
MLBr_02162|M.leprae_Br4923          NLISDVILGCVSPVGDQGGDIARATVLAAGLPVTAGGVQLNRFCASGLEA
                                      :.**  * :. :* *.*: .* : **.* *  . *. ::* *.*. :*

TH_0166|M.thermoresistible__bu      VHFAAQGVMSGTVDLIVAGGVQKMSQFPILSAFAAGEPYGATDPWTGCEG
MAV_5069|M.avium_104                VHFAAQAVMSGTCDLIVAGGVQKMSQFPILCAFEAGEPFGSSDPWTGCEG
Mb3586c|M.bovis_AF2122/97           ISFGAQAIMSGTADVIVAGGVQNMSQIPISSAMTVGEQFGFTSPTNESKQ
Rv3556c|M.tuberculosis_H37Rv        ISFGAQAIMSGTADVIVAGGVQNMSQIPISSAMTVGEQFGFTSPTNESKQ
MMAR_5045|M.marinum_M               ISFGAQAIMSGTADLIVAGGMQNMSQIPISSAMIVGEQFGFSSPTNESKQ
MUL_4119|M.ulcerans_Agy99           ISFGAQAIMSGTADLIVAGGMQNMSQIPISSAMIVGEQFGFSSPTNESKQ
Mflv_1484|M.gilvum_PYR-GCK          ISFGAQAIMSGTADLIVAGGMQNMSQIPISSAMTVAEQFGFTSPTNESKS
Mvan_5282|M.vanbaalenii_PYR-1       ISFGAQAILSGTADLIVAGGMQNMSQIPISSAMIVGEQFGFTSPTNESKS
MSMEG_6008|M.smegmatis_MC2_155      ISFGAQAIMSGTADIILAGGMQNMSWVPISSAMIVGKELGFSTPTAESEY
MAB_0600|M.abscessus_ATCC_1997      ISFAAQAVMSGTADLIVAGGFQNMSQIPISAAMLVGKEYGFTSPTAESEG
MLBr_02162|M.leprae_Br4923          VNTAAQKVRSGWDDLVLAGGVESMSRVPMGSD---GGAMGLDPATN----
                                    :  .** : **  *:::***.:.** .*: .    .   *   .      

TH_0166|M.thermoresistible__bu      WQARYGDQEISQFRGAEMIAEHWKLSREDNEKFALESHRRAVAAIEAGYF
MAV_5069|M.avium_104                WQARYGDQEISQFRGAEMIASQWNLSREDNERFALASHQRAVTAISEGRF
Mb3586c|M.bovis_AF2122/97           WLHRYGDQEISQFRGSELIAEKWNLSREEMERYSLTSHERAFAAIRAGHF
Rv3556c|M.tuberculosis_H37Rv        WLHRYGDQEISQFRGSELIAEKWNLSREEMERYSLTSHERAFAAIRAGHF
MMAR_5045|M.marinum_M               WLHRYGDQEISQFRGSEMIAEKWNLSREEMEQYALTSHARAFAAIRGGRF
MUL_4119|M.ulcerans_Agy99           WLHRYGDQEISQFRGSEMIAEKWNLSREEMEQYALTSHARAFAAIRGGRF
Mflv_1484|M.gilvum_PYR-GCK          WLHRYGDQEISQFRGSELIAEKWNLSREEMEQYALMSHHRAQAAIRAGHF
Mvan_5282|M.vanbaalenii_PYR-1       WLHRYGDQEISQFRGAEMIAEKWDISREDMEQFALTSNQRAQAAIRAGHF
MSMEG_6008|M.smegmatis_MC2_155      WRHRYGDQEISQFRGSELIAERWDISREEMEQFALSSHQRAFAAIRAGHF
MAB_0600|M.abscessus_ATCC_1997      WLHRYGDQEISQFRGAEMIAEKWDISREEMERFALSSHEKAFAAIRNGHF
MLBr_02162|M.leprae_Br4923          ----YDVMFVPQGIGADLIATIEGFSRDDVDVYALRSQEKAAAAWSGGYF
                                        *.   :.*  *:::**    :**:: : ::* *: :* :*   * *

TH_0166|M.thermoresistible__bu      DKEITPYA----DATVD--EGPRPDTSLEKMASLPTLIEG----------
MAV_5069|M.avium_104                TREIIPFA----GVSVD--EGPRANTSLEKMAGLPTLVEG----------
Mb3586c|M.bovis_AF2122/97           ENEIITVETESGPFRVD--EGPR-ESSLEKMAGLQPLVEG----------
Rv3556c|M.tuberculosis_H37Rv        ENEIITVETESGPFRVD--EGPR-ESSLEKMAGLQPLVEG----------
MMAR_5045|M.marinum_M               DNEILSVETESGPFRVD--EGPR-ESSLEKMAGLKTLVEG----------
MUL_4119|M.ulcerans_Agy99           DNEILSVETESGPFRVD--EGPR-ESSLEKMAGLKTLVEG----------
Mflv_1484|M.gilvum_PYR-GCK          ENEIIPVQTDGAGFATD--EGPR-DTSLEKMAGLKTLVEG----------
Mvan_5282|M.vanbaalenii_PYR-1       ENEIIDVD----GFRVD--ECPR-ETTLEKMAGLKTLVDG----------
MSMEG_6008|M.smegmatis_MC2_155      DNEIVPVG----DFGVD--EGPR-ETTLEKMAALQPLVEG----------
MAB_0600|M.abscessus_ATCC_1997      DNEIIPVG----DFRVD--EGPR-ESTLEKLASLNPLVEG----------
MLBr_02162|M.leprae_Br4923          AKSVVPVRDQNGLLILDHDEHMRPDTSKEGLAKLKPAFEGLAAMGGFDDV
                                     ..:            *  *  * ::: * :* * . .:*          

TH_0166|M.thermoresistible__bu      ------------GVLTAAVASQISDGAAALLVASKDAVDRFNLTPRARIH
MAV_5069|M.avium_104                ------------GVLTAAVASQISDGAAALLIASQDAVDRFGLNPRARVH
Mb3586c|M.bovis_AF2122/97           ------------GRLTAAMASQISDGASAVLLASERAVKDHGLRPRARIH
Rv3556c|M.tuberculosis_H37Rv        ------------GRLTAAMASQISDGASAVLLASERAVKDHGLRPRARIH
MMAR_5045|M.marinum_M               ------------GRLTAAMASQISDGASAVLLASEQAVKDHGLTPRARIH
MUL_4119|M.ulcerans_Agy99           ------------GRLTAAMASQISDGASAVLLASEQAVKDHGLTPRARIH
Mflv_1484|M.gilvum_PYR-GCK          ------------GRLTAAMASQISDGASAVLLASEDAVKAHGLKPRARIH
Mvan_5282|M.vanbaalenii_PYR-1       ------------GRLTAAMASQISDGASAVLLASENAVKVHNLKPRARIH
MSMEG_6008|M.smegmatis_MC2_155      ------------GRLTAALASQISDGASAVLLASEQAVKEHNLKPRARIH
MAB_0600|M.abscessus_ATCC_1997      ------------GRLTAALASQISDGGSATLVASERAVKAHGLTPRARVH
MLBr_02162|M.leprae_Br4923          ALQKYHWVEKINHVHTGGNSSGIVDGAALVMIGSEAVGKSQGLTPRARMV
                                                   *.. :* * **.:  ::.*: . .  .* ****: 

TH_0166|M.thermoresistible__bu      HMSVRGADPVMMLTAPIPATQHALKRAGMSIDDIDAVEINEAFAPVVLAW
MAV_5069|M.avium_104                HMSVRGSDPVMMLTAPIPATQHALKRTGLSIDDIDTVEINEAFAPVVLAW
Mb3586c|M.bovis_AF2122/97           HISARAADPVFMLTGPIPATRYALDKTGLAIDDIDTVEINEAFAPVVMAW
Rv3556c|M.tuberculosis_H37Rv        HISARAADPVFMLTGPIPATRYALDKTGLAIDDIDTVEINEAFAPVVMAW
MMAR_5045|M.marinum_M               HISARAADPVFMLTGPIPATRHALEKTGLSIDDIATVEINEAFAPVVLAW
MUL_4119|M.ulcerans_Agy99           HISARAADPVFMLTGPIPATRHALEKTGLSIDDIATVEINEAFAPVVLAW
Mflv_1484|M.gilvum_PYR-GCK          HISARGADPVFMLTGPIPATRYALDKTGLTIDDIDTVEINEAFAPVVQAW
Mvan_5282|M.vanbaalenii_PYR-1       HISARGADPVFMLTGPIPATQYALDRAGLTIEDIDTVEINEAFAPVVQAW
MSMEG_6008|M.smegmatis_MC2_155      HISARGADPVMMLTGPIPATEYALKKTGLSIDDIDTVEINEAFAPVVLAW
MAB_0600|M.abscessus_ATCC_1997      HISARGDDPVFMLTGPIPATRYALEKTGLTMDDIDVVEINEAFAPVVLAW
MLBr_02162|M.leprae_Br4923          ATATSGADPVIMLTGPTPATRKVLDRAGLTVDDIDLFELNEAFASVVLKF
                                      :. . ***:***.* ***. .*.::*::::**  .*:*****.**  :

TH_0166|M.thermoresistible__bu      LAELGADPARVNPNGGAIALGHPIGCTGARLMTSLLHHLERTGGRYGLQT
MAV_5069|M.avium_104                LAELGADPVKVNPNGGAIALGHPIGCTGARLMTSMLHELERTGGRFGLQT
Mb3586c|M.bovis_AF2122/97           LKEIKADPAKVNPNGGAIALGHPLGATGAKLFTTMLGELERIGGRYGLQT
Rv3556c|M.tuberculosis_H37Rv        LKEIKADPAKVNPNGGAIALGHPLGATGAKLFTTMLGELERIGGRYGLQT
MMAR_5045|M.marinum_M               LKEIKADPEKVNPNGGAIALGHPLGATGAKLFTTMLNELDRVGGRYGLQT
MUL_4119|M.ulcerans_Agy99           LKEIKADPEKVNPNGGAIALGHPLGATGAKLFTTMLNELDRVGGRYGLHT
Mflv_1484|M.gilvum_PYR-GCK          LKETKADPEKVNPSGGAIALGHPLGATGAKLFATMLNTLERTGGRYGLQT
Mvan_5282|M.vanbaalenii_PYR-1       LKETKADPEKVNPNGGAIALGHPLGATGAKLFATMLNTLERTGGRYGLQT
MSMEG_6008|M.smegmatis_MC2_155      IKDLKADPEKVNPNGGAIALGHPLGATGAKLFATMLNTLERTGGRYGLQT
MAB_0600|M.abscessus_ATCC_1997      AKELDVDLKKVNPNGGAMALGHPLGATGAKLFATMLNELERTGGRYGLQT
MLBr_02162|M.leprae_Br4923          QKDLNIPDEKLNVNGGAIAMGHPLGATGAMILGTMVDELERCNARRALVT
                                      :      ::* .***:*:***:*.*** :: :::  *:* ..* .* *

TH_0166|M.thermoresistible__bu      MCEGGGQANVTIIERL-
MAV_5069|M.avium_104                MCEGGGQANVTIIERL-
Mb3586c|M.bovis_AF2122/97           MCEGGGTANVTIIERL-
Rv3556c|M.tuberculosis_H37Rv        MCEGGGTANVTIIERL-
MMAR_5045|M.marinum_M               MCEGGGTANVTIIERL-
MUL_4119|M.ulcerans_Agy99           MCEGGGTANVTIIERL-
Mflv_1484|M.gilvum_PYR-GCK          MCEGGGTANVTIIERLS
Mvan_5282|M.vanbaalenii_PYR-1       MCEGGGTANVTIIERL-
MSMEG_6008|M.smegmatis_MC2_155      MCEGGGTANVTIIERL-
MAB_0600|M.abscessus_ATCC_1997      MCEGGGTANVTIIERL-
MLBr_02162|M.leprae_Br4923          LCIGAGMGVATIIERV-
                                    :* *.* . .*****:

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_0166	fadA6	-	100% (386)	PROBABLE ACETYL-CoA ACETYLTRANSFERASE FADA6 (ACETOACETYL-CoA THIOLASE)
M. thermoresistible (build 8)	TH_2071	fadA6	e-146	65.30% (389)	PROBABLE ACETYL-CoA ACETYLTRANSFERASE FADA6
M. thermoresistible (build 8)	TH_0255	-	e-107	52.32% (388)	acetyl-CoA acetyltransferase