For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_0173 ()

annotation: CONSERVED HYPOTHETICAL PROTEIN
coordinates: 381744 - 382919
length: 392

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0173-100% (392)CONSERVED HYPOTHETICAL PROTEIN
M. thermoresistible (build 8)TH_2804-6e-0661.76% (34) PUTATIVE -
M. thermoresistible (build 8)TH_0177-4e-0531.82% (88) CONSERVED HYPOTHETICAL PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0383c-1e-16876.94% (386) hypothetical protein Mb0383c
M. gilvum PYR-GCKMflv_1574-1e-16176.16% (365) hypothetical protein Mflv_1574
M. tuberculosis H37RvRv0376c-1e-16876.94% (386) hypothetical protein Rv0376c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2924c-3e-8948.25% (371) hypothetical protein MAB_2924c
M. marinum MMMAR_0654-1e-17078.98% (371) hypothetical protein MMAR_0654
M. avium 104-----
M. smegmatis MC2 155MSMEG_0743-1e-17481.99% (372) xanthine dehydrogenase
M. ulcerans Agy99MUL_0114-7e-1629.59% (267) hypothetical protein MUL_0114
M. vanbaalenii PYR-1Mvan_5182-1e-15975.00% (372) hypothetical protein Mvan_5182

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1574|M.gilvum_PYR-GCK          --------------MWEAGGTAGLSTVVRTMKSAPRPPGAAMVVSPDGTV
Mvan_5182|M.vanbaalenii_PYR-1       ----MRDVLDELLAVWRSGETAGLSTVVRTMQSAPRPPGAAMVVGPDGAV
Mb0383c|M.bovis_AF2122/97           ------------MAIWAAGDTAGVATVVRTLRSAPRPPGAAMVVAPDGSV
Rv0376c|M.tuberculosis_H37Rv        ------------MAIWAAGDTAGVATVVRTLRSAPRPPGAAMVVAPDGSV
MMAR_0654|M.marinum_M               ----MRDVLTDLITIWRAGDTAGLATVVRTLRSAPRPPGASMVVAPDGSV
TH_0173|M.thermoresistible__bu      -------VLDGLLPVWRSGDTAGLATVVRTFRSAPRLPGAAMVVAPDGTV
MSMEG_0743|M.smegmatis_MC2_155      MLGGVRDVLGTLSAVWESGGTAGVGTVVRTFRSAPRPAGASMVVAPDGTV
MAB_2924c|M.abscessus_ATCC_199      ----MKDILRDLIAVLEGGGTAALARVVEVSGAVPREPGAAMIVPADGPV
MUL_0114|M.ulcerans_Agy99           ---MQMTISERAAQLLAARTPFVHATVVRAQPPTSAYPGDEAILLPDGTI
                                                  :  .  .   . **..  ...  .*   :: .**.:

Mflv_1574|M.gilvum_PYR-GCK          AGSVSGGCVEGAVYETANEVITGGAPHLQRYGVSDDDAFSVGLTCGGIID
Mvan_5182|M.vanbaalenii_PYR-1       AGSVSGGCVEAAVYEVANDVVASGVPELQRYGISDDDAFTVGLTCGGTID
Mb0383c|M.bovis_AF2122/97           SGSVSGGCVEGAVYELAAEVAQTGIPRLEHYGVSDDTAFAVGLTCGGIID
Rv0376c|M.tuberculosis_H37Rv        SGSVSGGCVEGAVYELAAEVAQTGIPRLEHYGVSDDTAFAVGLTCGGIID
MMAR_0654|M.marinum_M               SGSVSGGCVEGAVYESAGEVTRTGIPRLERYGVSDDDAFAVGLTCGGIID
TH_0173|M.thermoresistible__bu      SGSVSGGCVEGAVYELATEVIQTGRPRLQRYGVSDDDAFSVGLTCGGTLD
MSMEG_0743|M.smegmatis_MC2_155      SGSVSGGCVEGAVYDLATEVVATGTPVLQRYGVSDDDAFEVGLTCGGILD
MAB_2924c|M.abscessus_ATCC_199      VGSLSGGCVEAAVIETAREVLAIGLCVSERFGIDDG--IAPGLTCGGEIE
MUL_0114|M.ulcerans_Agy99           EGFVGGQCAQNSVRKAALGVLQAGESVLLRVLPDGDVHFPEAPGACVVVN
                                     * :.* *.: :* . *  *   *     :   ...  :  .  .   ::

Mflv_1574|M.gilvum_PYR-GCK          IFTEPVSRNTFPQLRDVATAIAEHRAVAVATVIAHPDPARVGRRIIVGTD
Mvan_5182|M.vanbaalenii_PYR-1       VFTEPVSRETFPQLQQVADDIAAHRPVAVATVIVHPDPKRVGLRLVVGRD
Mb0383c|M.bovis_AF2122/97           VFVEPVSRATFPELGELADDIGAQRPVAIATVIAHPDERRVGRRLVIRPD
Rv0376c|M.tuberculosis_H37Rv        VFVEPVSRATFPELGELADDIGAQRPVAIATVIAHPDERRVGRRLVIRPD
MMAR_0654|M.marinum_M               IFIEAVSPATFPELVAVAEDIAAHVPVAVATVIAHPDPQWVGRRLVVRTD
TH_0173|M.thermoresistible__bu      VFVEAVSQNSFPELADLVGDIEAHRPVATATVIAHSDPGWVGRRLVLRPD
MSMEG_0743|M.smegmatis_MC2_155      VFVEPVSQKTFPQLGAIRDDIEAQRPVAVATVITHPDAQWIGRRLVVHTD
MAB_2924c|M.abscessus_ATCC_199      VVTEHIGAERFPLLRELRSALVAGEPMGLVSTLSG-----IPDWALVR--
MUL_0114|M.ulcerans_Agy99           PCLS----------------------------------------------
                                       .                                              

Mflv_1574|M.gilvum_PYR-GCK          SR----QGSVGSPRADDAVADDARGLLLAGRSAVLSYGPDGQRQDAGMEV
Mvan_5182|M.vanbaalenii_PYR-1       SR----HGSLGSSRTDDAVTDDARGLLLAGRSGVLTYGADGQRQESGMEV
Mb0383c|M.bovis_AF2122/97           TK-SPVTGSLGSARADAAVIDDARGLLAVGRSEILEYGPDGQRRGEGMEV
Rv0376c|M.tuberculosis_H37Rv        TK-SPVTGSLGSARADAAVIDDARGLLAVGRSEILEYGPDGQRRGEGMEV
MMAR_0654|M.marinum_M               PS-RPTAGSLGSVRADAAVTDDARGLLALGRSEILKYGPDGQRRGEGMEI
TH_0173|M.thermoresistible__bu      HEDAPVSGSLGSPRADAAVTDDARGLLAAGRTEVLTYGPDGQRRGEGMEV
MSMEG_0743|M.smegmatis_MC2_155      ----EVAGSLGSSRADAAVTDDARGLLAAGRSEVLTYGPDGQRRGEGMEV
MAB_2924c|M.abscessus_ATCC_199      ---------AGEPAPWPQIEGDIVSLIRAGRSAVAGADRCEPDQSDLPRV
MUL_0114|M.ulcerans_Agy99           --------------------------------------------GGSLEI
                                                                                    .:

Mflv_1574|M.gilvum_PYR-GCK          FVSSYAPRPRMLVFGAIDFAAALAHQAAFLGYRVTVCDARPVFATEARFP
Mvan_5182|M.vanbaalenii_PYR-1       FVCSHAPRPKMLVFGAIDFASALARQATFLGYRVTVCDARPVFATAARFP
Mb0383c|M.bovis_AF2122/97           FVSSHAPRPRMLVFGAIDFAAALARQGSFLGYRVTVCDARAVFATPARFP
Rv0376c|M.tuberculosis_H37Rv        FVSSHAPRPRMLVFGAIDFAAALARQGSFLGYRVTVCDARAVFATPARFP
MMAR_0654|M.marinum_M               FVSSFAPRPRMLVFGAIDFAAALARQGSFLGYRVTVCDARAVFATRARFP
TH_0173|M.thermoresistible__bu      FVASYAPRPRMLVFGAIDFAAAVAQQASFLGYRVTVCDARAVFATPARFP
MSMEG_0743|M.smegmatis_MC2_155      FVSSYAPRPRMLVFGAIDFAAAVAQQGAFLGYRVTVCDARPVFATTARFP
MAB_2924c|M.abscessus_ATCC_199      FVQAFAAPPRMILAGANAFVRALSRTGSQLGYRVTVVDAREVFATPAHFP
MUL_0114|M.ulcerans_Agy99           FLTPQLPAPLVRIYGATPIAEALIEVCGVLGY-----DARRDSDPVGAAA
                                    *: .  . * : : **  :. *: .    ***     ***    . .  .

Mflv_1574|M.gilvum_PYR-GCK          AAEEVVVDWPHRYLAAQADLGLIDARTAICVLTHDPKFDVPVLEVALRLP
Mvan_5182|M.vanbaalenii_PYR-1       AAEEVVVDWPDRYLRAQAEQGEIDSRTAVCVLTHDPKFDVPVLEVALRLP
Mb0383c|M.bovis_AF2122/97           TADDVVVAWPHRYLAAQAEAGGIDERTVICVLTHDPKFDVPVLEVALRLG
Rv0376c|M.tuberculosis_H37Rv        TADDVVVAWPHRYLAAQAEAGGIDERTVICVLTHDPKFDVPVLEVALRLG
MMAR_0654|M.marinum_M               TADEVVVEWPSRYLAAEVQAGAIDERTVICVLTHDPKFDVPVLEVALRLP
TH_0173|M.thermoresistible__bu      TADEVVVEWPHRYLAAQAEAGAVDSRTAICVLTHDPKFDVPLLEVALRLP
MSMEG_0743|M.smegmatis_MC2_155      TADEVVVDWPHRYLAAQAEAGAIDARTVVCVLTHDPKFDVPLLEVALRLP
MAB_2924c|M.abscessus_ATCC_199      YADEVVVDWPHRYLRAEAAGGRVDARTVVCVLTHDPKFDVPMLAAALTVA
MUL_0114|M.ulcerans_Agy99           LPTAVVIAS----------HGGPEAENIRAALDNG---------------
                                     .  **:             *  : ..  ..* :.               

Mflv_1574|M.gilvum_PYR-GCK          DAGYIGVMGSRRTHEDRMSRLREAGLTETELARLASPIGLDLGARTPEET
Mvan_5182|M.vanbaalenii_PYR-1       ELDYIGVMGSRRTHHDRVRRLREAGLTDKELARLSSPIGLDLGARTPEET
Mb0383c|M.bovis_AF2122/97           -VGYVGAMGSRKTHDDRMDRLRAAGLTDAELSRLSSPIGLDLGARTPEET
Rv0376c|M.tuberculosis_H37Rv        -VGYVGAMGSRKTHDDRMDRLRAAGLTDAELSRLSSPIGLDLGARTPEET
MMAR_0654|M.marinum_M               RIGYVGAMGSRQTHDDRMSRLRAAGLTDAELSQLSSPIGLDLGARTPEET
TH_0173|M.thermoresistible__bu      EVGYIGAMGSRRTHEDRLERLRQAGLTDVELSRLSSPIGLDLGGRTPEET
MSMEG_0743|M.smegmatis_MC2_155      DIAYIGAMGSRRTHEDRLARLREAGLTEEELARLSSPIGLDLGGRTPEET
MAB_2924c|M.abscessus_ATCC_199      PVAFVGALGSRRTHTDRMARLREQGVTDDQLGRLRSPLGLDLNARTPEET
MUL_0114|M.ulcerans_Agy99           -VGYIGLVASKVRGAAVLDSLG---LSATERARIRTPVGLAIGAKTPAEI
                                       ::* :.*:      :  *    ::  : .:: :*:** :..:** * 

Mflv_1574|M.gilvum_PYR-GCK          AVSIAAEIIARRWGGGGRPLTETDGRIHHEA-----------------
Mvan_5182|M.vanbaalenii_PYR-1       AVSIAAEIIARRWGGDGRPLSQTDGRIHHPA-----------------
Mb0383c|M.bovis_AF2122/97           AVSIAADIIARRWGGGGRPLADIAGRIHHDAQVAGEFKDYLTRH----
Rv0376c|M.tuberculosis_H37Rv        AVSIAADIIARRWGGGGRPLADIAGRIHHDAQVAGEFKDYLTRH----
MMAR_0654|M.marinum_M               AVSIAADIIARRWGGGGRPLAETSGRIHRDLQVADDFEASAG------
TH_0173|M.thermoresistible__bu      AVSIAAEIIARQWGGTGRPLSETGGRIHHGGDPMKDHTSELSDPLSRY
MSMEG_0743|M.smegmatis_MC2_155      AVSIAAEIIAKRWGGEGRPLAETGGRIHH---ELGEHESAPAS-----
MAB_2924c|M.abscessus_ATCC_199      AISIAAQIIAETSGGSGRPLSDIDGPIHR-------------------
MUL_0114|M.ulcerans_Agy99           AVAIAAEIIAAVRAGGGAGPRRWMRLPPRRWTRCAG------------
                                    *::***:***   .* *           :